Clinical trials: Feeding and Eating Disorders
Eating Disorder
Monoamine Contributions to Neurocircuitry in Eating Disorders
This study will use brain imaging technologies to measure several neurotransmitters (serotonin and dopamine) that contribute to our abilities to respond to reward or inhibit our impulses, and which are known to be altered in the…
- Trial name
- NCT02020408
- Testing
- [11C]raclopride, [11C]DASB, amphetamine
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Premature Birth, Feeding and Eating Disorders of Childhood
Evaluation of an Interdisciplinary Decision Guide for Infant Feeding Assessment
Preterm infants are at risk for feeding problems which can persist through early childhood. These feeding problems may include oral motor, sensory, digestive, nutritional, respiratory, and/or behavioral components.
- Trial name
- NCT04850794
- Testing
- Decision Support Tool
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Anorexia Nervosa, Atypical Anorexia Nervosa
Optimizing Provider Training in Eating Disorders (OPTED)
This is a randomized controlled trial for mental health clinicians comparing two methods of training in family-based treatment (FBT) for restrictive eating disorders.
- Trial name
- OPTED (NCT05389657)
- Testing
- Web-based training, Live training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Binge-Eating Disorder
Binge Eating Liraglutide Intervention
The study is a 17-week, single-center, double-blind, parallel-group, randomized placebo controlled trial that will test the efficacy of liraglutide 3.0 mg/d as compared to placebo in reducing the number of binge episodes per…
- Trial name
- BELIEVE (NCT03279731)
- Testing
- Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Kelly Allison
Bulimia Nervosa, Eating Disorders
Effectiveness of Antibiotic Treatment for Reducing Binge Eating and Improving Digestive Function in Bulimia Nervosa
This study will determine the effectiveness of the antibiotic erythromycin in enhancing gastrointestinal function and decreasing the frequency of binge eating in people with bulimia nervosa.
- Trial name
- NCT00304187
- Testing
- Erythromycin
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Obesity, Cardiovascular Risk Factor
The Pitt Retiree Study: A Diabetes Prevention Program for Medicare Eligible Older Adults
The Pitt Retiree Study (PRS) disseminates a novel, yet practical, diabetes prevention program among Medicare eligible adults in Western Pennsylvania.
- Conditions
- Obesity, Cardiovascular Risk Factor, Eating Behavior, Diet Modification
- Trial name
- PRS (NCT03192475)
- Testing
- GLB plus phone contacts, GLB plus newsletter contacts
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Eating Disorders
Treatment Uptake Chatbot for Eating Disorders
Eating disorders (EDs) are serious mental illnesses associated with high morbidity and mortality, clinical impairment, and comorbid psychopathology.
- Trial name
- NCT04806165
- Testing
- Repeated Administration, Personalized Recommendation, Motivational Interviewing
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Washington University School of Medicine
Obesity, Weight Loss
Behavioral Mechanism of Energy Compensation With Exercise
Over 70% of Americans are either overweight or obese, putting them at risk for many chronic diseases including diabetes. Exercise is commonly used as a weight loss and weight loss maintenance strategy.
- Conditions
- Obesity, Weight Loss, Eating Behavior
- Trial name
- NCT04651218
- Testing
- exericse
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kyle Flack
Binge-Eating Disorder, Obesity
Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Specialist Treatment
This study will test the effectiveness of cognitive-behavioral therapy as a specialist treatment for binge eating disorder (BED) in patients with obesity.
- Trial name
- NCT03063606
- Testing
- Cognitive-Behavioral Therapy (CBT), NB Medication (on-going from acute treatment)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Yale University
Major Depressive Disorder
A Personalized Approach to Effects of Affective Bias Modification on Symptom Change and Rumination
This study evaluates the effect of a computerized intervention for depressive symptoms called Affective Bias Modification (ABM).
- Trial name
- NCT04137367
- Testing
- Affective bias modification
- Where
- Norway
- Volunteers
- 108 people
- Sponsor
- University of Oslo
Binge-Eating Disorder
Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating Disorder
This study will test the efficacy of naltrexone HCI and bupropion HCI (NB) versus placebo in patients with binge-eating disorder (BED), with or without obesity.
- Trial name
- NCT03539900
- Testing
- Bupropion Hydrochloride, Naltrexone Hydrochoride Drug Combination
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Yale University
Food Neophobia, Picky Eating
Weighted Blanket to Treat Anxiety Related to Trying New Foods the Pediatric Population
This small experimental pilot study addresses the knowledge gap related to the use of weighted blankets for children with anxiety related to food and eating.
- Conditions
- Food Neophobia, Picky Eating, Avoidant Restrictive Food Intake Disorder, Anxiety State
- Trial name
- Food Anxiety (NCT06420232)
- Testing
- weighted blanket
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Binge-Eating Disorder, Obesity
Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Maintenance Therapy
This study will test the effectiveness and relative efficacy of naltrexone/bupropion medication as a maintenance therapy for the treatment of binge eating disorder (BED) in patients with obesity.
- Trial name
- NCT03047005
- Testing
- NB medication (Naltrexone Bupropion combination)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Yale University
Anxiety Disorders, Depressive Disorder
Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations
The prevalence of mental health problems among college populations has risen steadily in recent decades, with one third of today's students struggling with anxiety, depression, or an eating disorder (ED).
- Conditions
- Anxiety Disorders, Depressive Disorder, Eating Disorders
- Trial name
- iAIM EDU (NCT04162847)
- Testing
- SilverCloud Health Intervention
- Where
- 4 sites in United States
- Volunteers
- 6,205 people
- Sponsor
- Washington University School of Medicine
Anorexia Nervosa, Osteopenia
IGF-1 and Bone Loss in Women With Anorexia Nervosa
Anorexia nervosa is an eating disorder that can cause thinning of the bones (a decrease in bone density). A significant decrease in bone density is called osteopenia or osteoporosis.
- Conditions
- Anorexia Nervosa, Osteopenia, Osteoporosis
- Trial name
- NCT01406444
- Testing
- rhIGF-1, Risedronate
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Massachusetts General Hospital
Bulimia Nervosa
Self-Control in Bulimia Nervosa
This study examines the influence of acute fasting and eating on self-control in adult females with and without bulimia nervosa (BN).
- Trial name
- NCT04409457
- Testing
- fasting state, fed state, magnetic resonance imaging
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Anorexia Nervosa, Bulimia Nervosa
App-Based Mindfulness Training for Individuals With Anorexia Nervosa and Bulimia Nervosa
We will evaluate the acceptability and feasibility of a 8-week long digital mindfulness-based intervention for anorexia nervosa and bulimia nervosa.
- Conditions
- Anorexia Nervosa, Bulimia Nervosa, Anorexia Nervosa, Atypical, Bulimia; Atypical
- Trial name
- NCT05753410
- Testing
- Mindful Courage
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Yeshiva University
Anorexia Nervosa
Dopamine Receptor Contributions to Prediction Error and Reversal Learning in Anorexia Nervosa
Anorexia nervosa (AN) is an eating disorder associated with intense fear of weight gain, food refusal, and severe weight loss. AN has the highest mortality rate among the psychiatric disorders; however, little is known about…
- Trial name
- NCT04128683
- Testing
- amisulpride, bromocriptine
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Binge-Eating Disorder, Obesity
Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Acute Treatment
Brief Summary: This study will compare the effectiveness of cognitive behavioral therapy (CBT), lisdexamfetamine (LDX), and the combination of CBT and LDX for the treatment of binge-eating disorder in patients with obesity.
- Trial name
- NCT03924193
- Testing
- Lisdexamfetamine Dimesylate, Cognitive-Behavioral Therapy, Combination LDX and Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Yale University
Obesity
Time Restricted Eating for Weight Loss Maintenance
The aim of this pilot feasibility and acceptability, randomized clinical trial will be to examine the effects of two-time restricted eating (TRE) interventions on weight loss maintenance (WLM).
- Trial name
- TWIST (NCT05742165)
- Testing
- Time Restricted Eating (TRE)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- NYU Langone Health