Clinical trials: Female Adolescents
Menstrual Cycle Abnormal
The Impact of Whole-Body Vibration and Relaxation Techniques on Adolescent Athlete Girls With Triad Syndrome"
This study aims to explore the effects of Whole-Body Vibration (WBV) exercises and relaxation techniques on adolescent female athletes who are experiencing Female Athlete Triad Syndrome - a condition that may include low bone…
- Trial name
- WBV for triad (NCT07587346)
- Testing
- whole body vibration device, relaxation training
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- MTI University
Breast Cancer
Long-Term Effect of Adolescent Diet on Hormones and Breast Cancer Risk in Women Previously Enrolled in the Dietary Intervention Study in Children
RATIONALE: The amount and type of fat in the diet may affect hormone levels, bone mineral density, and breast density later in life. This may affect the risk of developing breast cancer.
- Trial name
- NCT00458588
- Testing
- physiologic testing, questionnaire administration, breast imaging study
- Where
- 10 sites in United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Chlamydia Infection
Chlamydia Trachomatis Persistence in the Female Gastrointestinal Tract
The purpose of this study is to determine if Chlamydial infections persist in the rectum of females who have had a sexually transmitted infection of Chlamydia.
- Trial name
- NCT00578188
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Body Image, Eating Disorder Symptom
Evaluating the Impact of Body Image Edutainment on Adolescent Girls' Body Image
Body image is one of the leading concerns for young people. These concerns may can have serious consequences, including anxiety, depression, risk taking behaviours, eating disorders and suicidal ideation.
- Trial name
- NCT04587726
- Testing
- Girl's room video, Control video - Chicken Girls
- Where
- United Kingdom
- Volunteers
- 686 people
- Sponsor
- University of the West of England
Depression
Effect of Virtual Reality on Depression in Adolescent Females
The purpose of this study is to investigate the effect of virtual reality on depression in adolescent females.
- Trial name
- NCT07452341
- Testing
- Virtual reality headset, Selective serotonin reuptake inhibitors(SSRIs)
- Volunteers
- 48 people
- Sponsor
- Cairo University
Sickle Cell Disease Vaso-occlusive Crisis
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents With Sickle Cell Disease During Vaso-Occlusive Crisis
This is a phase 2, randomized, multiple-dose, placebo-controlled study designed to evaluate the safety, efficacy, and pharmacokinetics (PK) of CSL889 (human hemopexin) when given intravenously (IV) to adults and adolescents with…
- Trial name
- NCT06699849
- Testing
- CSL889
- Where
- 30 sites in United States, Turkey (Türkiye) and 1 more
- Volunteers
- 70 people
- Sponsor
- CSL Behring
HIV Infections, Contraception
Pharmacokinetic Study of Long-acting Antiretrovirals and Contraceptives in HIV
This study is being done to understand how long-acting injectable cabotegravir (CAB-LA) used for HIV pre-exposure prophylaxis (PrEP) and hormonal contraceptive methods affect each other when used at the same time.
- Conditions
- HIV Infections, Contraception, Drug-drug Interaction, PrEP
- Trial name
- PHARAOH (NCT07516548)
- Testing
- Long-acting injectable cabotegravir (CAB-LA), No PrEP
- Where
- Botswana
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Phenylketonuria
The Effect of Supplemental Docosahexaenoic Acid (DHA) on Neurocognitive Outcomes in Teen and Adult Women With Phenylketonuria(PKU)
The purpose of this study is to determine if taking supplemental DHA improves measures of processing speed and executive function in teen and adult women with PKU.
- Trial name
- PKU&DHA (NCT00892554)
- Testing
- Docosahexaenoic Acid, Corn/soy oil
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Emory University
Exercise
A Multi-component Physical Activity Intervention for Adolescent Girls
A four-arm randomised pilot trial involving: 1. Physical activity programme only - live exercise sessions, social support, standardised text messages 2.
- Trial name
- NCT04766372
- Testing
- Behaviour change
- Where
- 3 sites in Ireland, United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Obesity
Effect of Recombinant Human Growth Hormone (rhGH) on Abdominal Fat and Cardiovascular Risk in Obese Girls
Teenagers and adults who are overweight or obese have an increase in fat in the abdomen, which increases their risk for diabetes and heart disease.
- Trial name
- NCT01169103
- Testing
- recombinant human growth hormone (rhGH)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Massachusetts General Hospital
Infections, Cytomegalovirus
A Study in Adolescent Females to Explore Cytomegalovirus Infection
The purpose of this study is to estimate the incidence of Cytomegalovirus (CMV) secondary infections (re-infections/re-activations) and the incidence of CMV primary infections in adolescent females.
- Trial name
- NCT01691820
- Testing
- Blood collection, Urine collection, Saliva collection
- Where
- 5 sites in United States, Finland and 1 more
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Adolescent Behavior, Borderline Personality Disorder
Connectivity and Social Cognition in Adolescent Girls With Borderline Personality Disorder, a Pilot Study
The disruption of social cognition associated with borderline personality disorder (BPD), and more specifically categorization of facial emotions, remains largely under-studied, despite the high frequency of this pathology in the…
- Trial name
- EEG-NIRS (NCT03139825)
- Testing
- Exploring the feasibility of learning during cognitive tasks (EEG-NIRS)
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Polycystic Ovary Syndrome, PCOS
Insulin Differences Between African-American and Caucasian Female Adolescents With Polycystic Ovary Syndrome (PCOS)
The purpose of this research study is to see if there are differences between African-American and Caucasian girls with Polycystic Ovary Syndrome (PCOS) in how their bodies respond to a type of sugar, called glucose, the body's…
- Trial name
- NCT02052479
- Testing
- Frequently Sampled Intravenous Glucose Tolerance Test (FSIVGTT)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Nationwide Children's Hospital
Vitamin D Deficiency
The Effect of Vitamin D on Bone Accretion and Turn-Over in Young Girls
Objectives To evaluate the effect of increased vitamin D intake on vitamin D status, bone mass and bone turnover in young girls aged 12-13.
- Trial name
- NCT00267540
- Testing
- cholecalciferol (D3) (vitamin)
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Type 2 Diabetes Mellitus, Diabetic Kidney Disease
Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)
Early diabetic kidney disease (DKD) occurs in 50-70% of youth with type 2 diabetes (T2D) and confers high lifetime risk of dialysis and premature death.
- Conditions
- Type 2 Diabetes Mellitus, Diabetic Kidney Disease, Adolescent Obesity, Pre Diabetes
- Trial name
- NCT05008276
- Testing
- Aminohippurate Sodium Inj 20%, Iohexol Inj 300 MG/ML, Dextran 40
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Petter Bjornstad
Mental Health Issue, Substance Use Disorders
Comparing the Effect of Adding a Remote Self-reporting Tool for Distress and Fit-for-purpose Mental Health & Addictions Service to Usual Case Management on Dropout Rates in a Vocational Training Program
Youth unemployment is a chronic problem in most societies. Some young adults are neither in employment, education or training (NEET), and are at high risk of chronic unemployment, social disengagement and poor quality of life.
- Conditions
- Mental Health Issue, Substance Use Disorders, Distress, Emotional
- Trial name
- TeachMeToBuild (NCT05626374)
- Testing
- Basic Case Management, Basic Case Management plus Distress Tool, Basic Case Management plus rapid mental health & addictions healthcare access
- Where
- Canada
- Volunteers
- 400 people
- Sponsor
- Royal Victoria Hospital, Canada
Respiratory Syncytial Virus Infections
A Study on the Safety and Immune Response to an Unadjuvanted RSV Maternal Vaccine, in High Risk Pregnant Women Aged 15 to 49 Years and Infants Born to the Vaccinated Mothers
The purpose of this study was to evaluate the safety, reactogenicity and immune response of a single intramuscular dose of the respiratory syncytial virus (RSV) maternal vaccine compared to placebo, when administered in the…
- Trial name
- NCT04980391
- Testing
- RSV MAT
- Where
- 35 sites in United States, Brazil and 7 more
- Volunteers
- 384 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Obesity
New Moves - Obesity Prevention Among Adolescent Girls
The New Moves study will evaluate the impact of a school based program for inactive high school girls who are overweight or at risk for being overweight due to low levels of physical activity.
- Trial name
- NCT00250497
- Testing
- New Moves
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Amenorrhea, Oligomenorrhea
Ovarian Morphology in Girls
Establishment of regular menstrual cycles is a key component of reproductive maturation and a recognized vital sign for health and well-being.
- Conditions
- Amenorrhea, Oligomenorrhea, Puberty
- Trial name
- OMG (NCT04424576)
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cornell University
IUCD Complication
Vaginal Isonicotinic Acid Hydrazide Administration Prior to Intrauterine Device Insertion
To investigate whether vaginal isonicotinic acid hydrazide administered before the levonorgestrel-releasing intrauterine system insertion reduces IUD insertion pain and difficulty in insertion in adolescents and young women.
- Trial name
- NCT04500015
- Testing
- INH
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Aswan University Hospital