Clinical trials: Female Breast Neoplasms
Mastectomy, Segmental, Breast Neoplasm Malignant Female
Safety and Performance of REGENERA Breast Implant in Women Affected by Malignant Breast Lesion Treated by Lumpectomy
The goals of this clinical trial are: demonstrate the safety of REGENERA breast implant in patients undergoing lumpectomy of malignant breast lesions demonstrate the safety and performance of REGENERA in terms of investigator's…
- Trial name
- NCT05941299
- Testing
- REGENERA breast implant implantation
- Where
- 9 sites in Italy, Spain
- Volunteers
- 92 people
- Sponsor
- Tensive SRL
Breast Neoplasm, Colon Neoplasm
A Study of MLN8054 in Patients With Advanced Solid Tumors
The purpose of this study is to determine (1) The side effects or toxicities of MLN8054;(2) The highest dose where side effects or toxicities are not too severe; (3) How MLN8054 is absorbed into the general blood circulation and…
- Conditions
- Breast Neoplasm, Colon Neoplasm, Pancreatic Neoplasm, Bladder Neoplasm
- Trial name
- NCT00249301
- Testing
- MLN8054
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Breast Cancer, Non-small Cell Lung Cancer
Integrated Molecular Profiling in Advanced Cancers Trial
Substantial progress has been made in the treatment of cancer through the use of targeted therapies, but what works for one patient might not work for another patient.
- Conditions
- Breast Cancer, Non-small Cell Lung Cancer, Colorectal Cancer, Genitourinary Cancer
- Trial name
- IMPACT (NCT01505400)
- Where
- Canada
- Volunteers
- 3,026 people
- Sponsor
- University Health Network, Toronto
BRCA1 Mutation, Breast Cancer
Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation
This phase III trial compares denosumab to placebo for the prevention of breast cancer in women with a BRCA1 germline mutation. A germline mutation is an inherited gene change which, in the BRCA1 gene, is associated with an…
- Conditions
- BRCA1 Mutation, Breast Cancer, Breast Diseases, Breast Neoplasms
- Trial name
- BRCA-P (NCT04711109)
- Testing
- Denosumab, Quality-of-Life Assessment
- Where
- 47 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Metastatic Malignant Neoplasm
A Study of NPX267 for Subjects With Solid Tumors Known to Express HHLA2/B7-H7
NPX267 is an antibody drug targeting the inhibitory receptor for B7-H7 (HHLA2) which may control evasion of the immune response in tumors.
- Trial name
- NCT05958199
- Testing
- NPX267
- Where
- 7 sites in United States
- Volunteers
- 131 people
- Sponsor
- NextPoint Therapeutics, Inc.
Breast Cancer, Gestational Trophoblastic Tumor
Interleukin-11 Plus Filgrastim Prior to Peripheral Stem Cell Transplantation in Patients With Non-Hodgkin's Lymphoma, Hodgkin's Disease, Breast Cancer, or Other Solid Tumors
RATIONALE: Interleukin-11 and filgrastim stimulate the production of blood cells. Giving these drugs to stimulate peripheral stem cells that can be collected for peripheral stem cell transplantation may result in fewer side…
- Conditions
- Breast Cancer, Gestational Trophoblastic Tumor, Kidney Cancer, Lymphoma
- Trial name
- NCT00004157
- Testing
- filgrastim, recombinant interleukin-11
- Where
- United States
- Sponsor
- Fred Hutchinson Cancer Center
Breast Cancer
Individualized Risk-Based Education in Promoting Breast Cancer Screening in Healthy Women
RATIONALE: Education, based on a patient's risk factors, may help promote breast cancer screening in healthy women. PURPOSE: This randomized clinical trial is studying individualized risk-based education to see how well it…
- Trial name
- NCT00416975
- Testing
- counseling intervention, educational intervention, evaluation of cancer risk factors
- Volunteers
- 899 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Breast Cancer
Compliance to a Hormone Therapy Regimen in Breast Cancer
RATIONALE: Understanding how well patients comply with their treatment regimen may help doctors plan the best treatment and ongoing care.
- Trial name
- NCT00666822
- Testing
- compliance monitoring, medical chart review, questionnaire administration
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer
Effect of Audiovisual Education on Breast Cancer
This study was conducted as a double-blind randomised controlled trial to determine the effect of education using audio-visual methods and simulation techniques on breast cancer screening and breast cancer fears in illiterate…
- Trial name
- NCT06898229
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Quality of Life, Breast Neoplasm Female
QOL of Women With HR-Positive Metastatic BC Treated in the First-line Setting: Comparison Between Public and Private Institutions.
Assess the quality of life in patients with hormone receptor positive, human epidermal growth factor receptor-type 2 negative metastatic breast cancer treated in first line (patients with new metastasis or recurrence during…
- Trial name
- BRAVE (NCT05287139)
- Testing
- Quality of Life
- Where
- Brazil
- Volunteers
- 202 people
- Sponsor
- Beneficência Portuguesa de São Paulo
Breast Cancer Female
Analysis of Circulating Epithelial Tumor Cells in Peripheral Blood in Patients With Primary Non-metastatic Breast Cancer Under Adjuvant Radiotherapy
The aim of this study was to investigate the systemic effect of radiotherapy on patients with primary non-metastatic breast cancer using CETC and to analyze possible changes in CETC quantity under adjuvant radiotherapy.
- Trial name
- NCT03935802
- Testing
- radiation
- Where
- Germany
- Volunteers
- 161 people
- Sponsor
- University of Jena
Breast Cancer
Longitudinal Evaluation of Taxane Induced Neuropathy in Early Stage Breast Cancer
Longitudinal Evaluation of Taxane induced neuropathy in early stage breast cancer.
- Trial name
- NCT02125019
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Cancer, Depression
Healing Touch in Treating Fatigue in Women Undergoing Radiation Therapy for Breast Cancer
RATIONALE: Healing touch therapy may be effective in lessening fatigue in women with breast cancer who are undergoing radiation therapy.
- Conditions
- Breast Cancer, Depression, Fatigue
- Trial name
- NCT00574145
- Testing
- Bio-field energy therapy, fatigue assessment and management, psychosocial assessment and care
- Where
- 3 sites in United States
- Volunteers
- 44 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Breast Cancer Prevention
Adherence to the Mediterranean Diet Among Women Attending Mammographic Screening
The PREVCAR study is a cross-sectional investigation aimed at evaluating dietary habits among women undergoing breast cancer screening.
- Trial name
- PREVCAR (NCT07016711)
- Testing
- Lifestyle and Nutrition Promotion
- Volunteers
- 35,000 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Breast Cancer
Raloxifene in Preventing Breast Cancer in Premenopausal Women
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of raloxifene may be an effective way to prevent breast cancer in premenopausal women.
- Trial name
- NCT00019500
- Testing
- raloxifene, evaluation of cancer risk factors
- Where
- United States
- Sponsor
- National Cancer Institute (NCI)
Breast Cancer, Ovarian Cancer
Efficacy of Paxman Scalp Cooling to Prevent Chemo Induced Alopecia in Black Patients With Breast or GYN Cancers
This study will measure the efficacy of scalp cooling with the Paxman Scalp Cooling (PSC) device in a diverse patient population with success measured as prevention of more than 50% hair loss during chemotherapy.
- Conditions
- Breast Cancer, Ovarian Cancer, Gynecologic Neoplasm, Endometrial Cancer
- Trial name
- NCT04626895
- Testing
- Paxman Scalp Cooling Device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medstar Health Research Institute
Breast Cancer
Study of Ribociclib With Everolimus + Exemestane in HR+ HER2- Locally Advanced/Metastatic Breast Cancer Post Progression on CDK 4/6 Inhibitor.
The purpose of this study is determine if the triplet combination of ribociclib, everolimus and exemastane is safe and effective in the treatment of locally advanced/metastatic breast cancer following treatment with a CDK 4/6…
- Trial name
- TRINITI-1 (NCT02732119)
- Testing
- Ribociclib, Everolimus, Exemestane
- Where
- 25 sites in United States
- Volunteers
- 104 people
- Sponsor
- Novartis Pharmaceuticals
Triple Negative Breast Cancer, TNBC - Triple-Negative Breast Cancer
A Study to Investigate LYL797 in Adults With Solid Tumors
This study will evaluate the safety and tolerability of LYL797, a ROR1-targeted CAR T-cell therapy, in patients with ROR1+ relapsed or refractory triple negative breast cancer (TNBC), non-small cell lung cancer (NSCLC)…
- Conditions
- Triple Negative Breast Cancer, TNBC - Triple-Negative Breast Cancer, Non-small Cell Lung Cancer, Non Small Cell Lung Cancer
- Trial name
- NCT05274451
- Testing
- LYL797
- Where
- 18 sites in United States
- Volunteers
- 57 people
- Sponsor
- Lyell Immunopharma, Inc.
Breast Cancer Female
Accelerated Partial Breast Irradiation Study
Breast cancer patients at Sentara RMH Hahn Cancer Center who are treated with accelerated partial breast irradiation will be monitored over a period of 10 years.
- Trial name
- APBI (NCT03437395)
- Testing
- Balloon Brachytherapy, 3D Conformal External Beam Irradiation
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Sentara Norfolk General Hospital
Patient Reported Outcome, Oncological Safety
Patient Report Outcome and Oncological Safety -Oncoplastic and Conventional BCS Cohort
Breast-conserving surgery (BCS) is the traditional surgical treatment for early-stage breast cancer patients. There are evidences indicating that oncoplastic BCS could improve cosmetic outcomes and/or quality of life, and has…
- Conditions
- Patient Reported Outcome, Oncological Safety, Breast-conserving Surgery, Breast Cancer Female
- Trial name
- NCT05054777
- Testing
- oncoplastic breast-conserving surgery, conventional breast-conserving surgery
- Volunteers
- 5,000 people
- Sponsor
- Shandong Cancer Hospital and Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.