Clinical trials: Female Breast Neoplasms
Hormone Receptor Positive Breast Cancer
A Global Study to Compare the Effects of Fulvestrant and Arimidex in a Subset of Patients With Breast Cancer.
The purpose of the study is to compare how treatment with Fulvestrant (FASLODEX) or Anastrozole (ARIMIDEX) effects disease progression for women with locally advanced or metastatic breast cancer who have not had prior hormonal…
- Trial name
- FALCON (NCT01602380)
- Testing
- faslodex 500mg, arimidex 1mg, faslodex dummy
- Where
- 118 sites in United States, Argentina and 18 more
- Volunteers
- 462 people
- Sponsor
- AstraZeneca
Breast Cancer Screening and Diagnosis
Contrast Enhancement Mammography vs MRI for the Surveillance of Women at High Risk of Breast Cancer: Con-trust Randomized Controlled Trial
Women at high risk of breast cancer (BC) should undergo annual magnetic resonance imaging (MRI) and digital mammography (DM) from at least ages 35 to 60.
- Trial name
- CEM (NCT06629896)
- Testing
- Contrast Enhancement Mammography, magnetic resonance imaging (MRI) and digital mammography (DM)
- Where
- Italy
- Volunteers
- 2,200 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Breast Neoplasms, Tamoxifen
The Clinical and Economic Impact of Pharmacogenomic Testing for Tamoxifen Metabolism in Postmenopausal Women Receiving Tamoxifen for Prevention of Recurrent Breast Cancer
This study will assess the impact of CYP450 2D6 genotype pharmacogenetic testing and the corresponding prescribing impact for postmenopausal women using tamoxifen in a patient care setting for prevention of recurrent breast…
- Trial name
- MHSLabCorp1 (NCT00830973)
- Testing
- Poor Metabolism Status Follow Up Therapy Considerations, CYP2D6 Inhibiting Drugs
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Medco Health Solutions, Inc.
Advanced Breast Cancer, Metastatic Breast Cancer
A Clinical Trial to Compare Efficacy and Tolerability of Fulvestrant 250mg, 250mg Plus 250mg Loading Regimen and 500mg
This study will assess the relationship between fulvestrant dose and efficacy in postmenopausal women with oestrogen receptor positive advanced breast cancer.
- Trial name
- FINDER II (NCT00313170)
- Testing
- Fulvestrant
- Where
- 34 sites in Belgium, Canada and 6 more
- Volunteers
- 144 people
- Sponsor
- AstraZeneca
Breast Cancer, Health Behavior
Effect of Planned Education on Health Beliefs and Fatalism in Women at High Risk of Breast Cancer
Purpose: This project aims to examine the effects of planned education on health beliefs and fatalism in women at high risk of breast cancer.
- Conditions
- Breast Cancer, Health Behavior, Breast Self-Examination
- Trial name
- NCT06690320
- Testing
- IMPLEMENTATION OF A PLANNED EDUCATION PROGRAM ON HEALTH BELIEF MODEL AND FATUALIST TENDENCIES IN WOMEN AT HIGH RISK OF BREAST CANCER
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ege University
Breast Cancer
The Effect of Dexmedetomidine of the Immune System
The goal of this research study is to learn about how dexmedetomidine (a standard of care sedative) affects your immune system (your defenses against cancer) by measuring your white blood cell levels before and after surgery.
- Trial name
- NCT01692210
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- M.D. Anderson Cancer Center
Breast Cancer, Breast - Female
The Effect of Health Education Conducted Using Two Different Methods on Women's Knowledge of Breast Cancer, Health Beliefs, Mammography Self-Efficacy, and Participation in Screening Programs
Breast cancer is the most common cancer among women worldwide and can be deadly if not found early. Screening tests like mammograms help find breast cancer early, which improves the chances of successful treatment.
- Trial name
- NCT07083310
- Testing
- Health Education, Motivational Interviewing
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Breast Cancer
Evaluation of Homeopathic Treatment for Hot Flashes in Non Metastatic Breast Cancer
The purpose of this study is to evaluate the efficacy of a homeopathic treatment (BRN01) in reducing hot flash scores after 4 weeks of treatment.
- Trial name
- HBC (NCT01246427)
- Testing
- BRN01
- Where
- 9 sites in France
- Volunteers
- 138 people
- Sponsor
- Centre Leon Berard
Breast Cancer
Identification of Biomarkers in Women at High Risk or Average Risk of Breast Cancer
RATIONALE: Collecting and storing samples of blood and studying them in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00897416
- Testing
- laboratory biomarker analysis
- Volunteers
- 1,452 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Female Breast Carcinoma, Healthy Subject
Technology and Health Communication in Improving Health Outcomes in Patients Scheduled for Mammography
This pilot clinical trial studies how well technology and health communication works in improving health outcomes in patients scheduled for mammography screening.
- Trial name
- NCT04290585
- Testing
- Questionnaire Administration, Telephone-Based Intervention
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Metastatic
NR in Chemo-induced Peripheral Neuropathy
The purpose of this single-arm phase II trial is to determine whether nicotinamide riboside (NIAGEN®) prevents the progression of peripheral sensory neuropathy in patients receiving infusions of paclitaxel or nab-paclitaxel for…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Metastatic, Platinum-resistant Recurrent Ovarian Cancer, Head and Neck Cancer Stage IV
- Trial name
- NCT03642990
- Testing
- Nicotinamide Riboside
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Donna Hammond, PhD
Postoperative Nausea and Vomiting, Breast Cancer Female
Ramosetron on Late PONV (Postoperative Nausea and Vomiting)
The purpose of this study was to evaluate the effectiveness of additional ramosetron injection for controlling late postoperative nausea and vomiting (PONV) after breast surgery in high risk PONV patients.
- Trial name
- NCT05326360
- Testing
- Ramosetron Hydrochloride
- Where
- South Korea
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
Breast Cancer Female, Alopecia
Hair-Safe Study: Scalp Cooling for Hair Saving in Women Undergoing Chemotherapy
Chemotherapy (CT) is a frequent and well established treatment in women with breast and gynecological tumors. Alopecia is one of the most common side effects of CT seriously impairing patient quality of life and body image.
- Trial name
- NCT04117815
- Testing
- Paxman Scalp Cooling System, Alopecia Assessments
- Where
- Austria
- Volunteers
- 128 people
- Sponsor
- Medical University Innsbruck
Malignancy, Non-hodgkin Lymphoma
A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors
This clinical trial is an interventional, active-treatment, open-label, multi-center, Phase 1/2 study. The study objectives are to assess the safety, tolerability and pharmacokinetics (PK) of CYT-0851 in patients with…
- Conditions
- Malignancy, Non-hodgkin Lymphoma, Multiple Myeloma, Breast Cancer
- Trial name
- NCT03997968
- Testing
- CYT-0851, CYT-0851 in combination with gemcitabine, CYT-0851 in combination with capecitabine
- Where
- 16 sites in United States
- Volunteers
- 169 people
- Sponsor
- Cyteir Therapeutics, Inc.
Breast Lesions, Breast Cyst
Survey of Optical Values of the Breast Using Radiation-Free Pressure-Free Optical Scanning
The purposes of this study is to establish normal optical values of breast tissue in the general population. This will allow for establishing normals for breast composition, and is expected to be useful in the classification of…
- Conditions
- Breast Lesions, Breast Cyst, Early-Stage Breast Cancer, Benign Growth, Breast
- Trial name
- NCT00671385
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Spectros Corporation
Breast Cancer Female
High Intensity Focused Ultrasound Treatment of Breast Tumors. BRIFU Study
Monocentric prospective study evaluating the efficacy of High intensity focused ultrasound (HIFU) in breast tumors.
- Trial name
- BRIFU (NCT03342625)
- Testing
- High Instensity Focused Ultrasound
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Institut Bergonié
Female Breast Cancer
PrefeRences And ChemoTherapy In Breast Cancer patiEnts
The aim of the present study is to ask women treated with adjuvant or neoadjuvant chemotherapy for breast cancer what survival benefit would justify the treatment.
- Trial name
- PRACTICE (NCT06332976)
- Testing
- Completion of questionnaires
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- European Institute of Oncology
Breast Neoplasms
SAKK - a Trial to Evaluate Antitumor Efficacy of Faslodex® After Aromatase Inhibitor Failure in Advanced Breast Cancer
The primary objective of the study is to assess the activity of fulvestrant in postmenopausal women with advanced breast cancer failing treatment with non-steroidal or steroidal aromatase inhibitors by estimating the Clinical…
- Trial name
- NCT00272740
- Testing
- Fulvestrant
- Where
- 8 sites in Belgium, Switzerland
- Volunteers
- 93 people
- Sponsor
- AstraZeneca
Breast Cancer, Advanced Breast Cancer
A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer
The reason for this study is to see if the study drug LY3484356 alone or in combination with other anticancer therapies is safe and effective in participants with advanced or metastatic breast cancer or endometrial cancer.
- Conditions
- Breast Cancer, Advanced Breast Cancer, Metastatic Breast Cancer, Endometrial Cancer
- Trial name
- EMBER (NCT04188548)
- Testing
- LY3484356, Abemaciclib, Everolimus
- Where
- 74 sites in United States, Australia and 6 more
- Volunteers
- 379 people
- Sponsor
- Eli Lilly and Company
Breast Cancer, Breast Cancer in Young Women
Interventions to Increase Screening by Breast Cancer Survivors and Their High Risk Female Relatives
The University of Michigan (UM) Schools of Nursing, Public Health, and Medicine, the Michigan Department of Community Health (MDCH) and the Michigan Cancer Consortium (MCC) are conducting a multidisciplinary academic/practice…
- Conditions
- Breast Cancer, Breast Cancer in Young Women, Breast Cancer in Women With a Strong Family History
- Trial name
- NCT01612338
- Testing
- Targeted, Enhanced Tailored
- Where
- 2 sites in United States
- Volunteers
- 1,290 people
- Sponsor
- University of Michigan
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