Clinical trials: Female Fertility
Contraception
Transdermal Contraceptive Patch - Endometrial Effects Study
The aim of the present study is to investigate the effects of the transdermal patch on the endometrium in healthy women who require contraception.
- Trial name
- NCT00896571
- Testing
- Ethinylestradiol/Gestogene (BAY86-5016)
- Where
- Germany
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Bayer
Ovulation Induction
A Prospective, Multi-centric Observational Study to Determine the Mono-bifollicular Development in Infertile Women Subjected to Ovulation Induction With Follitropin α
This is a prospective and multicentric observational study to determine the real mono-bifollicular development rate that is obtained under normal care conditions following ovulation induction (OI) treatment with follitropin-alpha…
- Trial name
- P450 (NCT01111084)
- Testing
- Follitropin alpha (r-FSH)
- Where
- Spain
- Volunteers
- 410 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Women With Fertility Disorder
Effect of Glucagon on Uterine Contractility at the Time of Embryo Transfer in in Vitro Fertilization
The success of in vitro fertilization is based mainly on uterine implantation embryo. An excessive uterine contractility may interfere with implantation by a movement of the embryo in the uterus.
- Trial name
- NCT01674283
- Testing
- Glucagon
- Where
- Canada
- Sponsor
- Clinique Ovo
Fertility Disorders
Performance of CHLOE Algorithm on the Prediction of Blastocyst Formation
This is an observational, prospective, single-arm, multi-center, clinical study to evaluate the performance of CHLOE, an Artificial Intelligence (AI)-based software application, as adjunct information to support identifying…
- Trial name
- CHLOE (NCT05455281)
- Testing
- CHLOE
- Where
- 3 sites in United States, Israel
- Volunteers
- 55 people
- Sponsor
- Fairtility
Fertility
Measuring Core Body Temperature Using TempuRing
This study evaluates the safety and usability of a continuous temperature sensor for women. Data will compare the date of ovulation identified by the continuous temperature sensor to that of transvaginal ultrasound and serum…
- Trial name
- NCT02462278
- Testing
- TempuRing
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Prima-Temp, Inc
Polycystic Ovarian Syndrome, Infertility
Evaluation of the Mixture Myoinositol:D-chiro-inositol 3.6:1 in Women With Polycystic Ovary Syndrome
The aim of the present study is to evaluate the effect of increasing the proportion of D-chiro-inositol (DCI) in a combination with myo-inositol (MYO) in improving fertility in women with polycystic ovarian syndrome (PCOS).
- Trial name
- NCT03201601
- Testing
- D-chiro-inositol, Myoinositol
- Volunteers
- 60 people
- Sponsor
- Biosearch S.A.
Tolerability
Study to Investigate Single Ascending Oral Doses of AZD5213 in Healthy Male and Non Fertile Female Subjects
1. The main purpose of this study is to assess the safety and tolerability of AZD5213 after single oral doses. 2. Another purpose of this study is to evaluate the pharmacokinetics (also called PK - how the study drug enters and…
- Trial name
- NCT01121302
- Testing
- AZD5213
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Multifollicular Stimulation
An Observational Study to Compare the Dose of Gonal-fTM FbM Prescribed by the Doctor With the Recommendation of the Dose Calculator Consort and to Evaluate the Ease of Use of Pre-filled Pen of Gonal-fTM FbM Pen
This is a prospective, observational and multicentric study to compare the Gonal-f FbM (filled by mass) dose prescribed by the doctor with the Gonal-f FbM dose determined by the CONSORT (Consistency in r-FSH Starting doses for…
- Trial name
- NCT01080729
- Testing
- Recombinant-follicle stimulating hormone (r-FSH)
- Where
- Belgium
- Volunteers
- 25 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Fertility
An Exploratory Study to Investigate the Effect of FE 999302 When Given Together With Follitropin Delta During Controlled Ovarian Stimulation
This is a phase 1b clinical trial with Choriogonadotropin beta (FE999302) and Follitropin delta (Rekovelle). The trial is multicentre, randomized, partially double-blind, placebo-controlled, parallel-group investigating the…
- Trial name
- Celestial-1 (NCT06466486)
- Testing
- Follitropin delta, FE999302
- Where
- 15 sites in Belgium, Czechia and 3 more
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Infertility, Fertility
A Trial to Compare the Efficacy and Safety of Ovarian Stimulation With GONAL-f® and Luveris® Starting on Day 1 Versus Day 6 in Women Undergoing Assisted Reproductive Technique
This is a phase IIIb, interventional, multicenter, multinational, randomised, open-label, comparative trial which primary objective is to generate data on the ovarian stimulation profile obtained when Luveris® is started either…
- Conditions
- Infertility, Fertility, Follicle Stimulating Hormone Deficiency
- Trial name
- NCT01497197
- Testing
- GONAL-f®, Luveris®, Recombinant human chorionic gonadotropin (r-hCG)
- Where
- United Arab Emirates
- Volunteers
- 174 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Healthy
Positron Emission Tomography (PET) Study
The primary purpose is to study the occupancy at the α4β2 neuronal nicotinic receptor's (NNRs) and to determine the relation between plasma concentration of AZD1446 and the occupancy at α4β2 NNRs.
- Trial name
- NCT00886067
- Testing
- AZD1446, 2-[18F]-F-A85380
- Where
- Sweden
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Endometriosis, Adhesive
Prevention of Adhesions During Celioscopy for Endometriosis. Impact of the Use of Anti-adhesion Treatment on Clinical Signs and Fertility at One Year
Thus is a longitudinal, prospective, multicentric observational study performed in mainland France, among a sample of gynaecology surgeons practising at endometriosis "expert" centres.
- Trial name
- ENDHY (NCT02612818)
- Testing
- Coelioscopy
- Where
- France
- Volunteers
- 364 people
- Sponsor
- Nordic Pharma SAS
Contraception, Bleeding Pattern
Assessment of a Vaginal Ring With Meloxicam on Ovarian Cycle in Fertile Women
In this study, the investigators propose to assess if a non-hormonal agent is absorbed by a local route (vaginal) and to observe the effect on follicular development.
- Trial name
- NCT01839643
- Testing
- Meloxicam 2.4 g, Meloxicam 3.0 g
- Where
- Chile
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Laboratorios Andromaco S.A.
Endometriosis
Pilot Study on a Dietary Supplement With EndoGen™ as Adjunct Therapy in Women With Endometriosis
Current treatments for endometriosis, such as NSAIDs and hormone therapies, are meant for long-term use but often cause side effects, including stomach, liver, heart, and kidney issues; allergies; and hormonal problems like…
- Trial name
- NCT07228975
- Testing
- MetrioFen Gocce
- Where
- 7 sites in Italy
- Volunteers
- 36 people
- Sponsor
- Endok s.r.l.
Healthy Volunteer
AZD2423 Single Ascending Dose Study in Healthy Japanese Subjects
This is a Phase I, single centre, randomised, double-blind, placebo-controlled, parallel group study to assess the safety, tolerability and pharmacokinetics of AZD2423 following single ascending dose administration to healthy…
- Trial name
- JSAD (NCT00970775)
- Testing
- AZD2423
- Where
- 2 sites in United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Amenorrhea, Fertility
A Study to Measure Pharmacokinetic (PK) Concentrations of Gonadotropin-Releasing Hormone Delivered by the OmniPod Pump
One of the Causes of Amenorrhea is hypothalamic amenorrhea, which is a deficiency in the amplitude and/or frequency of endogenous Gonadotropin-releasing hormone (GnRH) Pulses.
- Conditions
- Amenorrhea, Fertility, Infertility
- Trial name
- NCT07152730
- Testing
- Lutrepulse
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Infertility, Vaginal Flora Imbalance
Evaluate the Use of a New Probiotic Strain in Couples With Fertility Problems and Dysbiosis.
Pilot study to evaluate the effect of the strain Lactobacillus PS11610 on the microbiota of the female and male genital tract in couples with fertility problems.
- Conditions
- Infertility, Vaginal Flora Imbalance, Genital Disorder
- Trial name
- PROFEC (NCT03701893)
- Testing
- Lactobacillus PS11610
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Healthy Japanese Young and Elderly Male and Non-fertile Female Volunteers
A Two-part Single and Multiple Dose Study to Assess the Safety , Pharmacokinetics and Effects of AZD3293 in Healthy Japanese Young and Elderly Volunteers
This study consists of two parts, ie, single dose part with young healthy subjects (Part 1) and single and multiple dose part with elderly healthy subjects (Part 2), to assess the safety, tolerability, pharmacokinetics and…
- Trial name
- NCT02005211
- Testing
- AZD3293
- Where
- Japan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Fertility Disorders
Effect of a Probiotic on the Female Genital Tract Microbiota of Participants With Fertility Disorders.
In the last decades, numerous publications have broken the old paradigm that considered the urogenital tracts as sterile, demonstrating that microorganisms present in the urogenital tract represent the 9% of the whole human…
- Trial name
- PROFEC II (NCT06122207)
- Testing
- Probiotic
- Where
- 2 sites in Portugal, Spain
- Volunteers
- 120 people
- Sponsor
- ProbiSearch SL
Healthy
A Study to Compare Two Different Tablet Formulations of AZD8931 in Healthy Males and Females
A study to compare two different tablet formulations of AZD8931 in healthy males and females.
- Trial name
- NCT01330758
- Testing
- AZD8931
- Where
- United Kingdom
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- AstraZeneca