Clinical trials: Female Genital Disease
Polycystic Ovary Syndrome
The Effect of Therapy Combination in PCOS With Dlbs 3233
The effect of combination therapy dlbs 3233 and clomifen citrate vs clomifen citrate on homa ir, maturation follicle, and menstrual cycle in PCOS cases at Muhammadiyah Asri Medical Center Hospital
- Trial name
- NCT07403201
- Testing
- dlbs 3233 , clomifen citrat
- Where
- Indonesia
- Volunteers
- 90 people
- Sponsor
- Inlacinpenelitian
Ovarian Cancer, Recurrent Cancer
A Study to Evaluate the Efficacy and Safety of CYH33 in Patients With Recurrent/Persistent Ovary Clear Cell Carcinoma
The purpose of this study is to determine the treatment efficacy of CYH33 monotherapy in patients with recurrent or persistent ovarian, fallopian tube or primary peritoneal clear cell carcinoma harboring PIK3CA hotspot mutation…
- Trial name
- NCT05043922
- Testing
- CYH33
- Where
- 36 sites in China, Japan
- Volunteers
- 93 people
- Sponsor
- Haihe Biopharma Co., Ltd.
Epithelial Ovarian Carcinoma
Study of Paclitaxel, Carboplatin and Oral Metformin in the Treatment of Advanced Stage Ovarian Carcinoma
Initially, the prospect of metformin as a neoplastic treatment was considered for malignancies of the prostate, colon and pancreas.
- Trial name
- NCT02437812
- Testing
- Metformin, Paclitaxel, Carboplatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Gynecologic Oncology Associates
Breast Cancer, Drug/Agent Toxicity by Tissue/Organ
Amifostine Followed by High Dose Chemotherapy in Treating Patients With Hematologic Cancer or Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs such as amifostine may protect normal cells from the side effects of chemotherapy.
- Conditions
- Breast Cancer, Drug/Agent Toxicity by Tissue/Organ, Lung Cancer, Lymphoma
- Trial name
- NCT00003269
- Testing
- sargramostim, amifostine trihydrate, cisplatin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Scripps Health
Ovarian Cancer
Innovative Ovarian Cancer Biomarker Assays
Ovarian cancer is often diagnosed at a later stage because early symptoms can be mild or non-specific. Earlier detection of ovarian cancer could improve treatment options and outcomes.
- Trial name
- DISARM CSB (NCT07693894)
- Testing
- Investigational ovarian cancer biomarker assays
- Where
- 7 sites in Czechia, Greece and 3 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Cervical Cancer
AK104 in Neoadjuvant Treatment of Cervical Cancer
Phase II open label study to evaluate the safety and efficacy of AK104 (anti-PD-1 and CTLA-4 bispecific antibody) in neoadjuvant treatment of cervical cancer.
- Trial name
- NCT05227651
- Testing
- AK104
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Akeso
Endometrial Cancer
Endometrial Cancer International Database
This project aims to determining prognostic factors and individualizing management decision per patient characteristics and endometrial cancer features.
- Trial name
- ECID (NCT04787159)
- Volunteers
- 1,000 people
- Sponsor
- Assiut University
Pancreatic Cancer, Metastatic Castration-resistant Prostate Cancer
Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy
Study of NGM120 in subjects with advanced solid tumors and pancreatic cancer (Part 1 and 2) and metastatic castration resistant prostate cancer (Part 3).
- Conditions
- Pancreatic Cancer, Metastatic Castration-resistant Prostate Cancer, Bladder Cancer, Melanoma
- Trial name
- NCT04068896
- Testing
- NGM120 30mg, NGM120 100mg, NGM120 30mg with Gemcitabine and Abraxane
- Where
- 20 sites in United States
- Volunteers
- 89 people
- Sponsor
- NGM Biopharmaceuticals, Inc
Polycystic Ovary Syndrome
Serum Anti-Mullerian Hormone (AMH) Levels in Overweight and Obese Adolescent Girls With Polycystic Ovaries
In this study the investigators aimed to investigate whether there is a relation between body weight and serum anti mullerian hormone levels in adults with polycystic ovary syndrome.
- Trial name
- NCT01856894
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Genital Warts, Human Papilloma Virus
Typing of Human Papilloma Virus (HPV) From Female Genital Warts
This is a longitudinal observational study of women presenting to Groote Schuur Hospital with genital warts. The study will evaluate the socio-demographic characteristics of the women using a structured questionnaire.
- Trial name
- NCT01192282
- Testing
- Medical / Surgical Treatment
- Where
- South Africa
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Solid Tumors
Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of escalating doses of RMC-4630 monotherapy in adult participants with relapsed/refractory solid tumors…
- Trial name
- NCT03634982
- Testing
- RMC-4630
- Where
- 12 sites in United States
- Volunteers
- 133 people
- Sponsor
- Revolution Medicines, Inc.
Missed Abortion
Oxytocin Effectiveness in First Trimester Dilatation and Curettage
The aim of this study is to investigate the impact of oxytocin on perioperative blood loss during the D\&C procedure, as well as to assess early and late complications associated with it's use.
- Trial name
- NCT06469203
- Testing
- Oxytocin, Sodium Chloride 0.9% Inj
- Volunteers
- 160 people
- Sponsor
- Assuta Ashdod Hospital
Genito Urinary Cancer, Bladder Cancer
Reconstitution of a Human Immune System in a Patient Derived Xenograft (PDX) Model of Genitourinary (GU) Cancers
The objective of this study is to obtain human blood CD34+ hematopoietic stem/progenitor cells (HSPCs) to reconstitute a match human immune system in our PDX model.
- Conditions
- Genito Urinary Cancer, Bladder Cancer, Kidney Cancer, Prostate Cancer
- Trial name
- Immune PDX (NCT03134027)
- Testing
- Bone marrow biopsy, Tumor biopsy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Duke University
Breast Cancer, Malignant Female Reproductive System Neoplasm
Effect of Yoga in Reducing Chemotherapy Induced Nausea and Vomiting
This randomized controlled three arm study compares the effects of a yoga intervention with jacobsons progressive muscle relaxation training and only standard of care in chemotherapy naive cancer patients.
- Conditions
- Breast Cancer, Malignant Female Reproductive System Neoplasm, Lymphomas, Chemotherapy-induced Nausea and Vomiting
- Trial name
- NCT01387841
- Testing
- yoga, Jacobsons PMRT group
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bharath Charitable Cancer Hospital and Institute
Pre-Eclampsia
Impact of Antichlamydial Treatment on the Rate of Preeclampsia
This randomized, double blinded controlled trial included 1200 healthy primigravidae who attended an outpatient clinic at 16-20weeks of pregnancy.
- Trial name
- NCT03233880
- Testing
- Azithromycin 1gm
- Where
- Egypt
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Polycystic Ovary Syndrome
The Effect of Cipralex on Quality of Life, Adrenal Activity Glucose Metabolism, Physical and Mental Health in PCOS
Objectives: To investigate the effect of Cipralex versus placebo on stress hormones, glucose metabolism, physical and mental health and quality of life in polycystic ovary syndrome(PCOS). Treatment: 2x20 women for 12 weeks.
- Trial name
- NCT01961180
- Testing
- Cipralex
- Where
- Denmark
- Volunteers
- 42 people
- Sponsor
- Odense University Hospital
Cervical Cancer, HPV Infection
HPV DNA Self-sampling in a General Practitioner's Office.
One of the limitations of organized cervical screening in the Czech Republic is the lack of participation in preventive gynecological examinations.
- Conditions
- Cervical Cancer, HPV Infection, Precancerous Lesion
- Trial name
- ASTRA (NCT06253169)
- Testing
- HPV DNA self-test
- Where
- 2 sites in Czechia
- Volunteers
- 2,000 people
- Sponsor
- Patient Organization Veronica
Endometriosis
Fertility Preservation in Case of Endometriosis
Fertility Preservation is now considered as crucial for the well-being of women battling cancer. However, others indications have more recently emerged.
- Trial name
- PREFENDO (NCT03744754)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Head and Neck Cancer, Cervical Cancer
A Study of ILB2109 and Toripalimab in Patients With Advanced Solid Malignancies
This is a multicenter, open-label, phase Ib/IIa study. The first part of the study will evaluate the safety, tolerability and preliminary efficacy of ILB2109 and Toripalimab in patients with locally advanced or metastatic solid…
- Conditions
- Head and Neck Cancer, Cervical Cancer, Endometrial Cancer, Triple Negative Breast Cancer
- Trial name
- NCT05955105
- Testing
- ILB-2109, Toripalimab
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Innolake Biopharm
HIV Infections, Sexually Transmitted Diseases
A Peer-Oriented HIV Prevention Outreach Program for Individuals at High Risk for HIV and Other STIs
This study will determine the effectiveness of a peer outreach intervention in preventing HIV infection in adults at high risk for contracting HIV and other sexually transmitted diseases (STDs).
- Trial name
- NCT00183456
- Testing
- Peer-oriented intervention, Group cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
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