Clinical trials: Female Osteoporosis
Low Bone Mass, Low Bone Mineral Density
A Transiliac Crest Bone Histology and Histomorphometry Study in Postmenopausal Women With Low Bone Mass or Osteoporosis Previously Treated With Denosumab
To characterize the effects of discontinuation of denosumab therapy on variables of bone histology in postmenopausal women with low bone mass or osteoporosis.
- Conditions
- Low Bone Mass, Low Bone Mineral Density, Osteoporosis, Postmenopausal Osteoporosis
- Trial name
- NCT00887965
- Testing
- Previous denosumab
- Volunteers
- 15 people
- Sponsor
- Amgen
Postmenopausal Osteoporosis
Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis
A 12-month study to compare the efficacy and safety of abaloparatide-solid microstructured transdermal system (sMTS) with abaloparatide-subcutaneous (SC).
- Trial name
- NCT04064411
- Testing
- abaloparatide, abaloparatide solid microstructured transdermal system
- Where
- 97 sites in United States, Denmark and 3 more
- Volunteers
- 511 people
- Sponsor
- Radius Health, Inc.
Osteoporosis, Atypical Femoral Fracture
Fracture (FX) Improvement With Teriparatide: FiX-IT Study
This open label comparison study examines the hypothesis that teriparatide given immediately following repair of an atypical subtrochanteric or diaphyseal femoral shaft fracture will enhance healing and improve bone mineral…
- Trial name
- FiX-IT (NCT01705587)
- Testing
- teriparatide
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Susan L. Greenspan
Osteoporosis
Effectiveness of Smart-Video Based Game Therapy and Otago-Based Structured Exercises in Women With Osteoporosis
In this project, researchers evaluated the effects and differences of smart-video based game therapy and Otago-based structured exercises in women with osteoporosis; aimed to evaluate their applicability in women with…
- Trial name
- NCT06506409
- Testing
- Smart-Video Based Game Therapy, Otago Based Structured Exercise, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Medipol University
Postmenopausal Osteoporosis, Low Bone Mass
Study of TST002 Injection in Postmenopausal Women With Osteoporosis or Low Bone Mass
This is a randomized, double-blind, placebo- and active-controlled Phase II study evaluating the efficacy and safety of TST002 injection (a humanized monoclonal antibody) in postmenopausal women with osteoporosis or low bone…
- Trial name
- NCT07806331
- Testing
- Denosumab
- Volunteers
- 110 people
- Sponsor
- Transcenta Therapeutics (Hangzhou) Co., Ltd.
Bone Loss, Osteoporosis
Single Ascending-Dose Study to Characterize the Safety, Pharmacokinetics, and Pharmacodynamics of CEP-37251 in Healthy Postmenopausal Women
Study to Characterize the Safety, Pharmacokinetics, and Pharmacodynamics of CEP-37251 in Healthy Postmenopausal Women.
- Trial name
- NCT01159873
- Testing
- CEP-37251
- Where
- Australia
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cephalon
Osteoporosis, Postmenopausal Osteoporosis
Study to Evaluate the Safety and Efficacy of BA058 (Abaloparatide) for Prevention of Fracture in Postmenopausal Women
The purpose of this study is to determine whether BA058 (abaloparatide), a parathyroid hormone-related peptide, is effective in preventing fractures in postmenopausal women with severe osteoporosis who are at risk of fractures.
- Trial name
- ACTIVE (NCT01343004)
- Testing
- BA058 80 mcg, teriparatide
- Where
- 28 sites in United States, Argentina and 8 more
- Volunteers
- 2,463 people
- Sponsor
- Radius Health, Inc.
Osteoporosis, Postmenopausal
The Prevalence of Osteoporotic Vertebral Compression Fractures (OVCF) in Korean Post Menopausal Women
This is an observational study to investigate the prevalence of osteoporotic fractures in post menopausal patients. Post menopausal patients who visit OS(orthopedic surgery) including GHs(general hospitals) and clinics will be…
- Trial name
- TOP (NCT01381588)
- Testing
- Fracture evaluation
- Where
- South Korea
- Volunteers
- 1,136 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Postmenopausal Osteoporosis
A Study to Evaluate the Safety and Tolerability of MK0217 in Women (0217-219)
This study is to assess the safety and tolerability of MK0217 being evaluated to treat women with postmenopausal osteoporosis.
- Trial name
- NCT00092027
- Testing
- MK0217, alendronate sodium/Duration of Treatment: 6 months
- Volunteers
- 454 people
- Sponsor
- Organon and Co
Metabolic Syndrome, Fall Risk
Physical Activity and Disability Prevention in Postmenopausal Women
The aim of this clinical study is to examine the impact of physical activity on the physical and mental health of postmenopausal women, with a particular focus on the development of disability.
- Conditions
- Metabolic Syndrome, Fall Risk, Sarcopenia in Elderly, Osteopenia, Osteoporosis
- Trial name
- PADP-Women (NCT06781541)
- Testing
- Nordic walking, Strength training, Bungy Pump Exercises
- Where
- Poland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Osteoporosis
Efficacy of Cone Beam Computed Tomography in Diagnosing Osteoporosis
SUMMARY TITLE: "Efficacy of Cone Beam Computed Tomography derived radiomorphometric indices in screening of postmenopausal females for osteoporosis." RATIONALE: Osteoporosis is a disease of altered bone architecture affecting…
- Trial name
- NCT04365504
- Testing
- Dual energy X ray absorbtiometry
- Where
- India
- Volunteers
- 48 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Osteoporosis
Study of Multiple Oral Doses of Odanacatib (MK0822) in Healthy Adults (0822-002)
This study will assess the safety, tolerability, pharmacokinetics, and pharmacodynamics of once-daily multiple-dose administration of odanacatib (MK0822).
- Trial name
- NCT00769418
- Testing
- odanacatib
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Osteoporosis
Program to Prevent Osteoporosis in Girls
Osteoporosis is a condition defined by decreased bone mass. Osteoporosis generally affects older women and can lead to bone fractures. One way to prevent osteoporosis is to build strong, healthy bones during childhood.
- Trial name
- NCT00063024
- Testing
- Increased calcium intake, Weight-bearing physical activity
- Where
- United States
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Osteoporosis
Symbiotic Yogurt, Calcium Absorption and Bone Health in Young Adult Women
Prebiotics have been linked to increased calcium absorption in animal and human studies (particularly in adolescents and in premenopausal women).
- Trial name
- NCT03420716
- Testing
- yogurt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidad de la Republica
Female Infertility, NF-κB Ligand
Clinical Relevance of Modifying RANKL Signaling During Folliculogenesis
Female infertility presents a significant societal challenge that will be aggravated in the future due to delayed parenthood. Our translational research suggests that receptor activator of NF-κB ligand (RANKL) is a novel…
- Conditions
- Female Infertility, NF-κB Ligand, RANKL, Osteoporosis
- Trial name
- NCT07546552
- Testing
- Denosumab, PBS
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Osteoporosis
Compliance and Persistence With Osteoporosis Treatment and Attitude Towards Future Therapy Among Post-menopausal Israeli Women During Drug Treatment or Drug Holiday
The purpose of the study is to provide information about the rate of response and persistence to drug therapies for osteoporosis.
- Trial name
- CONTINUITY (NCT01854086)
- Testing
- Questionnaires about compliance and persistence with bisphosphonates treatment
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Meir Medical Center
Osteopenia, Sarcopenia
Effect of Electromyostimulation on Bone
Although there is some evidence that whole body electromyostimulation(WB-EMS) affect bone via its acute and longitudinal effects on muscle mass and strength, the corresponding impact on bone density and falls in older adults has…
- Conditions
- Osteopenia, Sarcopenia, Falls
- Trial name
- NCT01296776
- Testing
- wellness control group., whole-body electromyostimulation
- Where
- Germany
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Osteoporosis, Postmenopausal
A Study of Blosozumab (LY2541546) in Postmenopausal Female Participants
The purpose(s) of this study is to measure how much of the study drug gets into the blood stream and how long it takes the body to get rid of it when given in multiple doses, subcutaneously (SC) (by inserting a needle just under…
- Trial name
- NCT02109042
- Testing
- Blosozumab
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Postmenopausal Osteoporosis
Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effect of PTH134 at Increasing Doses in Healthy Postmenopausal Subjects
This study is designed to investigate the safety and tolerability of PTH134 in healthy subjects and to assess the exposure from PTH134.
- Trial name
- NCT00676312
- Testing
- PTH134
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- Novartis
Osteoporosis, Osteopenia
Isoflavones for Promoting Calcium Absorption and Preventing Bone Loss in Post Menopausal Women
Estrogen is a hormone that helps prevent calcium loss and bone breakdown. During menopause, estrogen levels decrease. Insufficient amounts of estrogen may lead to bone loss and possibly osteoporosis.
- Trial name
- NCT00244907
- Testing
- Genistein vs Risedronate
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Purdue University