Clinical trials: Female Reproductive Cancer
Cervical Carcinoma, Ovarian Carcinoma
Peer-to-Peer Support Program in Improving Quality of Life Outcomes in Patients With Gynecologic Cancer and Their Caregivers
This pilot clinical trial studies a peer-to-peer support program in improving quality of life outcomes in patients with gynecologic cancer and their caregivers.
- Conditions
- Cervical Carcinoma, Ovarian Carcinoma, Uterine Corpus Cancer, Vaginal Carcinoma
- Trial name
- NCT02412124
- Testing
- Supportive Care, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Polycystic Ovarian Syndrome, Infertility
Healthy Eating for Reproductive Health (HERHealth)
This study will be a 6-month intervention that is examining how different dietary approached may be useful for women with Polycystic Ovarian Syndrome (PCOS) who are attempting pregnancy, particularly by measuring changes in…
- Conditions
- Polycystic Ovarian Syndrome, Infertility, Obesity, Overweight
- Trial name
- HERHealth (NCT01509066)
- Testing
- Diet
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Cervical Cancer, Endometrial Cancer
Development and Management of Registry in Patients With Gynecologic Cancer in Korea
The goal of this observational study is to identify and analyze the characteristics, treatment trends, prognostic factors and survival prognosis of Korean gynecologic cancer patients.
- Conditions
- Cervical Cancer, Endometrial Cancer, Ovarian Cancer, Fallopian Tube Cancer
- Trial name
- NCT05912972
- Testing
- Patient registry
- Where
- South Korea
- Volunteers
- 13,500 people
- Sponsor
- Asan Medical Center
Gynecologic Cancer
3DUS Imaging of Needles in Gynecological Brachytherapy
Brachytherapy treatment in gynecological cancers is an essential component to delivering adequate doses of radiation to a tumour while sparing normal tissue.
- Trial name
- NCT04705467
- Testing
- Gynecological brachytherapy
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Western University, Canada
Endometrial Cancer Stage, Gynecologic Cancer
The Compatibility of Preoperative Endometrial Biopsies With Postoperative Final Pathology in Endometrial Cancer
Although there are many studies comparing preoperative and postoperative histological diagnoses in the literature, there are no studies evaluating the compatibility of preoperative histological diagnoses obtained from different…
- Trial name
- NCT04917341
- Testing
- re-evaluation of endometrial biopsy samples by a gynecopathologist working at a university hospital
- Volunteers
- 960 people
- Sponsor
- Batman Training and Research Hospital
Gynecologic Cancer, Surgery
GO SOAR1: Post-Operative Morbidity and Mortality Following Gynaecological Oncology Surgery
The Global Gynaecological Oncology Surgical Outcomes Collaborative (GO SOAR) will develop a network of gynaecological oncology surgeons, surgical departments and other interested parties that will have the long-term ability to…
- Conditions
- Gynecologic Cancer, Surgery, Surgery--Complications
- Trial name
- GO SOAR1 (NCT04579861)
- Testing
- Prospective data collection following gynaecological oncology surgery
- Where
- United Kingdom
- Volunteers
- 1,100 people
- Sponsor
- Faiza Gaba
Malignant Female Reproductive System Neoplasm, Recurrent Malignant Female Reproductive System Neoplasm
Self-Hypnosis for the Enhanced Recovery After Surgery in Patients With Gynecologic Cancer
This trial studies how well self-hypnosis works in enhancing recovery after surgery in patients with gynecologic cancer. A guided relaxation method called self-hypnosis may help affect how patients feel pain and symptoms after…
- Conditions
- Malignant Female Reproductive System Neoplasm, Recurrent Malignant Female Reproductive System Neoplasm, Metastatic Cervical Cancer
- Trial name
- NCT04266886
- Testing
- Best Practice, Hypnotherapy, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- M.D. Anderson Cancer Center
Polycystic Ovary Syndrome, Reproductive Medicine
Interest of Myo-inositol Supplementation in Women With Polycystic Ovarian Syndrome
The main objective will be to check if MyoInositol (MYO) reduces the total resistance rate to Clomiphene Citrate (CC). For this, our study will be controlled, randomized and double blinded.
- Trial name
- MYOPK (NCT03059173)
- Testing
- Myo-Inositol + Levomefolic acid, Clomiphene Citrate
- Where
- France
- Volunteers
- 276 people
- Sponsor
- University Hospital, Lille
Endometrial Serous Adenocarcinoma, Fallopian Tube Carcinoma
Comprehensive Patient Questionnaires in Predicting Complications in Older Patients With Gynecologic Cancer Undergoing Surgery
This research trial studies comprehensive patient questionnaires in predicting complications in older patients with gynecologic cancer undergoing surgery.
- Conditions
- Endometrial Serous Adenocarcinoma, Fallopian Tube Carcinoma, Malignant Female Reproductive System Neoplasm, Ovarian Carcinoma
- Trial name
- NCT02315469
- Testing
- Comprehensive Geriatric Assessment, Questionnaire Administration
- Where
- 393 sites in United States, Canada
- Volunteers
- 190 people
- Sponsor
- NRG Oncology
Head and Neck Cancer, Prostate Cancer
Improving Evidence-Based Care for Cancer Patients
The purpose of this study is to improve cancer care and the delivery of cancer care. Researchers are interested in studying patient reported information and examining how different factors may impact cancer care.
- Conditions
- Head and Neck Cancer, Prostate Cancer, Breast Cancer, Lung Cancer
- Trial name
- NCT03207594
- Testing
- Survey, Saliva sample, Smoking Status questions
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Medical University of South Carolina
PCOS- Polycystic Ovary Syndrome
The Synbiotics Effects in Polycystic Ovary Syndrome: A Randomized Controlled Trial
The goal of this clinical trial is to compare the effect of synbiotics and placebo in Thai women with polycystic ovary syndrome.
- Trial name
- PCOS (NCT06169566)
- Testing
- synbiotics
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maharaj Nakorn Chiang Mai Hospital
Frailty, Neuromuscular Blockade
Incidence of Residual Neuromuscular Blockade in Fraility in OncoGynae Surgery
Frailty among patients undergoing surgery is strongly associated with an elevated risk of adverse perioperative outcomes, heightened incidence of postoperative complications, increased mortality rates, and prolonged hospital…
- Conditions
- Frailty, Neuromuscular Blockade, General Anesthetic Drug Adverse Reaction, Gynecologic Cancer
- Trial name
- FIGO (NCT06216002)
- Testing
- Train of four nerve stimulator
- Where
- Thailand
- Volunteers
- 356 people
- Sponsor
- Mahidol University
Ovarian Cancer, Endometrial Cancer
Proactive Immune Tolerance Induction in Chemotherapy for Gynecologic Cancer
The goal of this clinical trial is to evaluate the efficacy of proactive immune tolerance induction of chemotherapy (paclitaxel and carboplatin) for patients with gynecologic cancer.
- Conditions
- Ovarian Cancer, Endometrial Cancer, Cervical Cancer
- Trial name
- NCT06977594
- Testing
- Proactive immune tolerance induction, Standard Treatment, Paclitaxel and carboplatin
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Seoul National University Hospital
Polycystic Ovary Syndrome, Metformin
Effects of Metformin on Metabolic and Reproductive Outcomes in Chinese PCOS Patients
Polycystic ovary syndrome (PCOS) is a reproductive endocrine disease characterized by reproductive and metabolic abnormalities, which is a crucial cause of female infertility and an essential risk factor for type 2 diabetes.
- Trial name
- NCT05463627
- Testing
- Metformin
- Where
- China
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Polycystic Ovary Syndrome, Assisted Reproduction
Mitochondrial DNA in Fresh Versus Frozen Embryo Culture Media of PCOS Women Undergoing In Vitro Fertilization
Ninety women with PCOS candidate for ICSI were randomized to 2 groups:Group A: fresh samples of PCOS patients undergoing IVF (no= 45) and Group B: frozen samples of PCOS patients undergoing IVF (no= 45).
- Trial name
- NCT03820167
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Colorectal Cancer, Hepatobiliary Cancer
Exercise Preconditioning with Cancer Surgeries
Studies have shown that people who are more physically fit prior to surgery do better after surgery. For this reason, it may be helpful for people who are going to have abdominal surgery for cancer to exercise before surgery to…
- Conditions
- Colorectal Cancer, Hepatobiliary Cancer, Gynecologic Cancer
- Trial name
- ExPre 01 (NCT04923672)
- Testing
- Moderate continuous exercise, High intensity interval exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Metastatic
Evaluating Efficacy and Tolerability of Anticancer Drug Therapies for the Treatment of Gynecologic and Breast Cancers
retrospective/prospective observational study. Objective of the study is to evaluate the effect of drugs in terms of objective responses, disease-free survival (DFS), progression-free survival (PFS), overall survival (OS), and…
- Conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3), Breast Cancer Metastatic, Ovarian Cancer, Cervical Carcinoma
- Trial name
- NCT06800612
- Testing
- Oncologic drugs administered for treatment of breast cancer, Oncologic drug administered for treatment of gynecologic cancer
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Cervical Cancers, Vaginal Cancers
Quality of Life and Sexuality After Pelvic Exenteration for Gynecologic Cancer
Pelvic exenteration is an exceptionally extensive and very rare surgical procedure, most commonly used in the treatment of locally recurrent cervical cancer among gynecological malignancies.
- Conditions
- Cervical Cancers, Vaginal Cancers, Vulvar Cancers, Endometrial Cancer
- Trial name
- NCT07594327
- Where
- Finland
- Volunteers
- 21 people
- Sponsor
- Tampere University Hospital
Gynecologic Cancer, Ovarian Cancer
Gyn Onc Prehab Study
Patients will be randomized to a unimodal or trimodal prehabilitation program prior to surgery for known or suspected gynecologic cancer.
- Conditions
- Gynecologic Cancer, Ovarian Cancer, Endometrial Cancer, Cervical Cancer
- Trial name
- NCT04298827
- Testing
- Unimodal, Trimodal
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Breast Cancer, Solid Tumors, Adult
First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors
Study STX-478-101 (LY4064809) is a multipart, open-label, phase 1/2 study evaluating the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of STX-478 (LY4064809) in participants with advanced solid…
- Trial name
- PIKALO-1 (NCT05768139)
- Testing
- STX-478, Fulvestrant, Ribociclib
- Where
- 65 sites in United States, Belgium and 7 more
- Volunteers
- 880 people
- Sponsor
- Eli Lilly and Company