Clinical trials: Female Sexual Arousal Disorder
Female Sexual Arousal Disorder
Multi-Center Study to Evaluate the Efficacy and Safety of Sildenafil Cream (3.6%) in Premenopausal Patients With Female Sexual Arousal Disorder
This study is looking to minimize side effects, while maintaining and potentially improving the therapeutic benefit to patients suffering from Female Sexual Arousal Disorder by providing a topical preparation of Sildenafil…
- Trial name
- RESPOND (NCT04948151)
- Testing
- Sildenafil
- Where
- 51 sites in United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Strategic Science & Technologies, LLC
Female Sexual Arousal Disorder
Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
Antidepressants have negative effects on genital arousal function that hinder quality of life and jeopardize medication adherence.
- Trial name
- NCT05685407
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
Hypoactive Sexual Desire Disorder, Vulvovaginal Disease
Effect of Testosterone Treatment on Clitoral Arteries' Hemodynamic Parameters.
The regulation of clitoral vascularization by sex steroids is still under-investigated. We aimed to explore the effects of 6 months transdermal Testosterone (T) therapy on clitoral color Doppler ultrasound (CDU) parameters in…
- Conditions
- Hypoactive Sexual Desire Disorder, Vulvovaginal Disease, Menopause Related Conditions, Dyspareunia (Female Excluding Psychogenic)
- Trial name
- TESTOFSD (NCT04336891)
- Testing
- Testosterone gel, Estradiol ovules, Moisturizer
- Where
- Italy
- Volunteers
- 81 people
- Sponsor
- University of Florence
Female Sexual Arousal Disorder, Hypoactive Sexual Desire Disorder
Bremelanotide in Premenopausal Women With Female Sexual Arousal Disorder and/or Hypoactive Sexual Desire Disorder
This trial is designed to evaluate the efficacy and safety of 3 fixed dose levels of bremelanotide, administered subcutaneously on an as-needed basis under conditions of home use, for the treatment of female sexual arousal…
- Trial name
- NCT01382719
- Testing
- bremelanotide
- Where
- 68 sites in United States, Canada
- Volunteers
- 612 people
- Sponsor
- Palatin Technologies, Inc
Hypoactive Sexual Desire Disorder
A Phase 3, Bridging, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Trial to Evaluate the Efficacy and Safety of Subcutaneously Administered Bremelanotide in Premenopausal Women With Hypoactive Sexual Desire Disorder (With or Without Decreased Arousal)
The purpose of this study is to Evaluate the Efficacy and Safety of Subcutaneously Administered Bremelanotide in Premenopausal Women with Hypoactive Sexual Desire Disorder(with or without Decreased Arousal).
- Trial name
- NCT04943068
- Testing
- Bremelanotide
- Where
- South Korea
- Volunteers
- 193 people
- Sponsor
- Kwang Dong Pharmaceutical co., ltd.
Hypoactive Sexual Desire Disorder (DSM-IV-TR Defined), Sexual Interest/Arousal Disorder (DSM-5 Defined)
Phase 1b/2a Unblinded Study of Responses in Premenopausal Women With HSDD to Lorexys Evaluating Efficacy and Safety
The purpose of this study is to investigate whether Lorexys is effective and safe to treat premenopausal women who have lost their sexual desire to a distressing degree.
- Trial name
- PURPLE (NCT01857596)
- Testing
- bupropion, Lorexys low-dose, Lorexys moderate-dose
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- S1 Biopharma, Inc.
Sexual Arousal Disorder
Using Thermography to Assess the Affects of Sildenafil Cream, 3.6%
The goal of this clinical trial is to compare thermography images in normal healthy premenopausal women after the application of Sildenafil Cream, 3.6%, L-arginine cream, and placebo cream.
- Trial name
- NCT05765487
- Testing
- Sildenafil, Vehicle
- Where
- Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Daré Bioscience, Inc.
Female Sexual Interest/Arousal Disorder
Study to Evaluate the Effectiveness and Safety of Libicare® in Women With Low Arousal and Sexual Desire Levels
The purpose of this study is to evaluate the effectiveness of Libicare® in the sexual desire and arousal at 12 weeks in peri or postmenopausal women aged between 40 and 60 years old with low sexual desire and arousal compared…
- Trial name
- VITAL (NCT04188600)
- Testing
- Libicare, active control
- Where
- Spain
- Sponsor
- Procare Health Iberia S.L.
Sexual Arousal Disorder
Evaluate the Safety and Efficacy of Bremelanotide in Women With Female Sexual Arousal Disorder (FSAD)
This 8 week at home study is designed to explore efficacy endpoints and evaluate the safety of intranasal Bremelanotide in women with Female Sexual Arousal Disorder. Efficacy will be assessed vs. a parallel placebo group.
- Trial name
- NCT00425256
- Testing
- Bremelanotide
- Where
- 20 sites in United States
- Sponsor
- Palatin Technologies, Inc
Sexual Dysfunction, Sexual Arousal Disorder
Clitoral Therapy Device in Alleviating Sexual Dysfunction After Genital Mutilation.
The aim of this study to determine the effect of clitoral therapy device EROS device/ on sexual dysfunction after genital mutilation.
- Trial name
- NCT05039775
- Testing
- EROS device, Psychosexual support
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Badr University
Sexual Dysfunction, Psychological
Zestra in Women With Mixed Sexual Dysfunction
The objective of this study is to evaluate the clinical efficacy and safety of Zestra(TM) in women with acquired mixed desire/interest/arousal/orgasm disorders under conditions of home usage.
- Trial name
- NCT00118495
- Testing
- Non-prescription Zestra(TM): patented formulation
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- QualiLife Pharmaceuticals
Menopause, Sexual Dysfunction
Transdermal Testosterone Gel for Female Sexual Interest and Arousal Disorder in Peri- and Post Menopause
Hypoactive sexual desire disorder (HSDD) is described as the most common form of female sexual dysfunction, particularly affecting peri- and postmenopausal women and is associated with significant distress and reduced quality of…
- Conditions
- Menopause, Sexual Dysfunction, Libido Disorder, Testosterone Deficiency
- Trial name
- TESTA MIND (NCT07408440)
- Testing
- Transdermal testosterone gel
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Female Sexual Dysfunction
the Ameliorating Effects of Antioxidant Gel on Female Arousal Disorder and Sexual Dysfunction
The aim of this study is to evaluate the quality of sexual life of females with sexual interest or arousal disorder before and after accurate application of a formulated emulgel made from natural ingredients, including kaempferol…
- Trial name
- NCT06060691
- Testing
- Kaempferol
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Deraya University
Sexual Dysfunction
Efficacy of Tibolone Versus Transdermal E2/NETA on Sexual Function in Naturally Postmenopausal Women (P06089)
Tibolone has been registered for treatment of menopausal symptoms. It is, however, not known what the effects are of tibolone in postmenopausal women diagnosed with sexual dysfunction.
- Trial name
- NCT00413764
- Testing
- tibolone, estradiol-norethisterone
- Volunteers
- 358 people
- Sponsor
- Organon and Co
Female Sexual Dysfunction
Cognitive-Behavioural & Mindfulness-Based Online Programs for Female Sexual Dysfunction
Female sexual dysfunction (FSD) affects approximately one-third of women worldwide and is linked to negative physical, psychological, and interpersonal outcomes.
- Trial name
- NCT05168371
- Testing
- Cognitive-Behavioural Therapy - Online (CBT-O), Mindfulness-Based Therapy - Online (MBT-O)
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- University of British Columbia
Female Sexual Arousal Disorder
Study to Investigate Effect of Sildenafil on Clitoral Engorgement as Measured by Magnetic Resonance Imaging (MRI) in Pre-menopausal Women With Female Sexual Arousal Disorder
The purpose of this study is to investigate the effect of 100 mg sildenafil on clitoral engorgement in pre-menopausal women, as well as examining the safety and toleration of the drug.
- Trial name
- NCT00640458
- Testing
- Sildenafil 100 mg
- Where
- 3 sites in United States, Australia
- Volunteers
- 20 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause
Effects of Ospemifene on Brain Activation Patterns in Women With Sexual Interest-arousal Disorders
Ospemifene is the first oral and non-hormonal treatment for moderate or severe vulvo-vaginal atrophy (VVA) in postmenopausal women who are not candidates to treatment with local oestrogens.
- Conditions
- Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause, Sexual; Disorder, Arousal, Female
- Trial name
- EROS (NCT04677491)
- Testing
- Ospemifene 60 mg, fMRI experiments
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital Clinic of Barcelona
Female Sexual Arousal Disorder
Heart Rate Variability Biofeedback for Female Sexual Arousal Disorder
Low resting heart rate variability (HRV) has been associated with sexual arousal problems and overall sexual dysfunction in women.
- Trial name
- NCT02958176
- Testing
- HRV Biofeedback, Autogenic Training
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Texas at Austin
Sexual Dysfunctions, Psychological
Group Psychoeducational Treatment for Women With Sexual Arousal Difficulties
The purpose of this study is to pilot test and determine the feasibility of a psychoeducational intervention (PED) we recently developed in a group format for women with acquired sexual arousal disorder (FSAD).
- Trial name
- NCT00175539
- Testing
- psychoeducational intervention
- Where
- 2 sites in Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sexual Dysfunctions, Psychological
Study of Pharmacological Treatment in Women With Female Sexual Interest/Arousal Disorder (FSIAD).
This clinical trial is a prospective, randomized, double-blind Phase III study with two arms to determine the efficacy and safety of the use of an IPDE in women with FSIAD.
- Trial name
- FSIAD (NCT04433559)
- Testing
- Tadalafil 1,5 mg oral tablets
- Volunteers
- 80 people
- Sponsor
- Lidia Larrañaga