Clinical trials: Female Sexual Dysfunction
Endometriosis, Dyspareunia
Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.
Dyspareunia is defined as pain with penetrative sexual intercourse. Women with endometriosis have a nine-fold increased risk of dyspareunia, when compared to the general female population.
- Conditions
- Endometriosis, Dyspareunia, Pelvic Pain
- Trial name
- NCT05540353
- Testing
- Transvaginal photobiomodulation
- Where
- 6 sites in United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Genito-Pelvic Pain/Penetration Disorder
Graded Motor Imagery in Women Diagnosed With Genito-Pelvic Pain Penetration Disorder
The goal of this clinical trial is to assess the effects of a Graded Motor Imagery (GMI) programme in women diagnosed with Genito-Pelvic Pain Penetration (GPPD) Disorder.
- Trial name
- NCT05637502
- Testing
- Graded Motor Imagery
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- University of Valencia
Vaginal Atrophy, Breast Cancer Female
Histological Modifications of Postmenopausal Vaginal Mucosa After Repeated Carbon Dioxide (CO2) Laser Treatment
To assess the long-term histological and clinical efficacy of MonaLisa Touch procedure for the management of the Genitourinary Syndrome of Menopause (GSM) in postmenopausal female patients.
- Conditions
- Vaginal Atrophy, Breast Cancer Female, Dyspareunia
- Trial name
- REPLAMOD (NCT04868812)
- Testing
- SmartXide 2 V 2 LR, MonaLisa Touch, DEKA, Florence, Italy
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS San Raffaele
Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8
Carbon Dioxide Fractional Laser in Treating Participants With Stage 0-III Hormone Receptor-Positive Breast Cancer With Vulvovaginal Atrophy
This phase II trial studies how well carbon dioxide fractional (CO2RE) laser works in treating participants with stage 0-III hormone receptor-positive breast cancer with vulvovaginal atrophy associated with dryness, inflammation…
- Conditions
- Anatomic Stage 0 Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8
- Trial name
- NCT03666819
- Testing
- Carbon Dioxide Fractional Laser, Questionnaire Administration
- Sponsor
- Mayo Clinic
Sexual Interest/Arousal Disorder
Cognitive-Behavioural Couple Therapy for Sexual Interest/Arousal Disorder
Sexual health is a fundamental aspect of quality of life; a satisfying sexual relationship is linked to better physical, psychological, and relationship health and well-being.
- Trial name
- CBCT for SIAD (NCT06777277)
- Testing
- Cognitive-behavioral therapy
- Where
- 3 sites in Canada
- Volunteers
- 170 people
- Sponsor
- Dalhousie University
Left Sided Heart Failure
Effect of Left Ventricle Diastolic Dysfunction on Outcomes in Female Cardiac Surgery Patients
The aim of this study is to evaluate the differences between males and females with LVDD, undergoing cardiac surgery. The investigators will look at perioperative factors such as body weight, body surface area, previous medical…
- Trial name
- EDISON (NCT05972356)
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Dysmenorrhea, Dyspareunia
Study Evaluating the Safety and Efficacy of ERB-041 on Reduction of Symptoms Associated With Endometriosis in Reproductive-Aged Women
The purpose of the study is to evaluate the efficacy and safety of two doses of ERB-041 (75 mg and 150 mg) relative to placebo on the relief of endometriosis-related symptoms (dysmenorrhea, pelvic pain, and deep dyspareunia) in…
- Conditions
- Dysmenorrhea, Dyspareunia, Endometriosis, Pelvic Pain
- Trial name
- NCT00318500
- Testing
- ERB-041
- Where
- 70 sites in United States, Australia and 5 more
- Volunteers
- 150 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Vulvar Atrophy, Vulvovaginal Signs and Symptoms
Retrospective Cohort Study of Symptoms and Quality of Life in Women With Genitourinary Syndrome of Menopause.
The goal of this clinical trial is to retrospectively identify the most prevalent symptoms of genitourinary syndrome of menopause (GSM) among postmenopausal women and to evaluate their impact on quality of life.
- Conditions
- Vulvar Atrophy, Vulvovaginal Signs and Symptoms, Genitourinary Syndrome of Menopause (GSM), Quality of Life
- Trial name
- NCT07737782
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Mucosa Innovations, S.L.
Female Sexual Dysfunction
Effect of Vaginal Electrical Stimulation on Female Sexual Dysfunction
vaginal electrical stimulation improves female sexual dysfunction
- Trial name
- EVESOFS (NCT02220946)
- Testing
- Vaginal Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Female Sexual Arousal Disorder
Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
Antidepressants have negative effects on genital arousal function that hinder quality of life and jeopardize medication adherence.
- Trial name
- NCT05685407
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
Female Sexual Dysfunction
Effect of Pelvic Organ Prolapse Surgeries on Female Sexual Function in Egyptian Women
study on female sexual function after different prolapse surgeries
- Trial name
- NCT03498443
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Beni-Suef University
Gynecological; Surgery (Previous), Causing Obstructed Labor
Impact of Early Physiotherapy on Pain, Quality of Life, Pelvic Floor Function, and Sexual Health Post-Episiotomy
Surgical incision of the perineum and the posterior vaginal wall during a vaginal delivery (episiotomy) is among the most common surgical procedures performed in obstetrics.
- Trial name
- NCT06568406
- Testing
- Physiotherapy, Urogynaecology
- Where
- Czechia
- Volunteers
- 250 people
- Sponsor
- Brno University Hospital
Menopause Related Conditions, Atrophic Vaginitis
Vaginal Hyaluronic Acid, Arginine and Liposome Gel Versus Vaginal Lubricant in Postmenopausal Women With Genitourinary Syndrome of Menopause
The goal of this interventional study is to compare the efficacy and safety of vaginal hyaluronic acid, arginine and liposome gel versus vaginal lubricant in the treatment of genitourinary syndrome of menopause in postmenopausal…
- Conditions
- Menopause Related Conditions, Atrophic Vaginitis, Genitourinary Syndrome of Menopause, Sexual Dysfunction
- Trial name
- VHAL (NCT06176820)
- Testing
- Vaginal Gel, Vaginal lubricant
- Volunteers
- 52 people
- Sponsor
- Sarawak General Hospital
Hypertension
Sexual Dysfunction in Hypertensive Women
Several studies describe the existence of an association between sexual dysfunction and high blood pressure (hypertension), most often characterized by a decrease in the number of orgasms and the existence of dyspareunia.
- Trial name
- DYSFHO (NCT05156385)
- Testing
- Blood sample for the determination of antihypertensives or their metabolites., Questionnaire on sexual activity, Scale on hospital anxiety and depression
- Where
- France
- Volunteers
- 348 people
- Sponsor
- University Hospital, Toulouse
Systemic Sclerosis, Vulvovaginal Signs and Symptoms
Effects of Fractional CO2 Laser Treatment on Vaginal Symptoms and Sexual Dysfunction in Women With Systemic Sclerosis
Women affected by Systemic Sclerosis and Vulvovaginal Atrophy will be submitted to a cycle composed of five vaginal CO2 laser treatment (SmartXide2 V2LR, Monalisa Touch, DEKA, Florence, Italy - Hi Scan V2LR con sonda vaginale a…
- Conditions
- Systemic Sclerosis, Vulvovaginal Signs and Symptoms, Sexual Function Disturbances
- Trial name
- SCLERDERMCO2 (NCT06231433)
- Testing
- CO2 Vaginal Laser
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- IRCCS San Raffaele
Hysterectomy, Ovariectomy
TDSM- Testosterone Dose Response in Surgically Menopausal Women
TDSM will study the physiology of testosterone in women ages 21-60 who have had surgical menopause (uterus and both ovaries removed).
- Conditions
- Hysterectomy, Ovariectomy, Menopause, Testosterone Deficiency
- Trial name
- NCT00494208
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Leukemia, Long-term Effects Secondary to Cancer Therapy in Adults
Ovarian Damage in Young Premenopausal Women Undergoing Chemotherapy for Cancer
RATIONALE: Comparing results of diagnostic procedures, such as ultrasound, done before, during, and after chemotherapy may help doctors learn about the side effects of chemotherapy and help plan the best treatment.
- Conditions
- Leukemia, Long-term Effects Secondary to Cancer Therapy in Adults, Long-term Effects Secondary to Cancer Therapy in Children, Lymphoma
- Trial name
- NCT00402935
- Testing
- laboratory biomarker analysis, fertility assessment and management, management of therapy complications
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Premature Ejaculation
A Safety and Tolerability Study of Administration of PSD502
A Phase I, Single-Centre, Double-Blind, Randomised, Placebo-Controlled, Parallel Group, Pharmacokinetic and Safety Study to Evaluate Systemic Exposure and Local Vaginal Exposure to Lidocaine and Prilocaine and the Metabolites 2,6…
- Trial name
- NCT01183208
- Testing
- Intervention A, Intervention B, Intervention C
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Plethora Solutions Ltd
Hydrocelectomy, Erectile Dysfunction
Assessment of Sexual Function in Male Patients Undergoing Hydrocelectomy and Their Partners
This study aimed to assess changes in sexual function in men undergoing hydrocelectomy and their partners. Male patients who underwent hydrocelectomy in our clinic between 2020 and 2024 were included in the study This study was…
- Conditions
- Hydrocelectomy, Erectile Dysfunction, Sexual Dysfunction Male, Sexual Dysfunction Female
- Trial name
- NCT07069985
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
Prostate Cancer (Adenocarcinoma), Radical Prostatectomy
Evaluation of Pelvic Floor Function and Psychosocial Sequelae Following Radical Prostatectomy for Prostate Cancer
This observational cross-sectional study aims to evaluate the effects of radical prostatectomy for prostate cancer on pelvic floor function and psychosocial well-being.
- Conditions
- Prostate Cancer (Adenocarcinoma), Radical Prostatectomy, Urinary Incontinence (UI), Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- NCT07693647
- Testing
- No Interventions
- Where
- Spain
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Valencia