Clinical trials: Female Sexual Dysfunction
Female Sexual Dysfunction
PK Study of Testosterone Nasal Gel (TBS-2) in Healthy Premenopausal Women
The purpose of this study was to assess the bioavailability of total testosterone through pharmacokinetic profiles obtained following (a) single administration of three doses of TBS-2 b) multiple administration TBS-2.
- Trial name
- NCT01364623
- Testing
- Low dose testosterone nasal gel, single dose, Medium dose testosterone nasal gel, single dose, High dose testosterone nasal gel, single dose
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Acerus Pharmaceuticals Corporation
Hysterectomy, Ovariectomy
TDSM- Testosterone Dose Response in Surgically Menopausal Women
TDSM will study the physiology of testosterone in women ages 21-60 who have had surgical menopause (uterus and both ovaries removed).
- Conditions
- Hysterectomy, Ovariectomy, Menopause, Testosterone Deficiency
- Trial name
- NCT00494208
- Testing
- Testosterone
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pelvic Floor Disorders, Urinary Incontinence
Effects of Epi-no Device on Pelvic Floor Dysfunctions
Perineal injury is the most common maternal obstetric complication associated with vaginal delivery. Perineal traumas are associated with maternal morbidity, including pain, urinary and fecal incontinence, genital prolapses…
- Conditions
- Pelvic Floor Disorders, Urinary Incontinence, Dyspareunia, Lacerations Perineal
- Trial name
- NCT04955418
- Testing
- Epi-No®, Evaluation
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Ehlers-Danlos Syndrome (EDS)
Impact of Ehlers-Danlos Syndrome on Gynaecological Health
Dysmenorrhea is a common problem in gynaecology, significantly impacting patients' quality of life. Ehlers-Danlos syndrome (EDS) is associated with joint hypermobility, tissue fragility and chronic pain.
- Trial name
- GYNESED (NCT07151274)
- Where
- France
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Endometriosis, Quality of Life
Quality of Life in Endometriosis - a Case Control Study
Endometriosis, one of the most common diseases of women during their reproductive period., may present a chronic disabling disease with major impact on women's life.
- Conditions
- Endometriosis, Quality of Life, Pain, Sexuality
- Trial name
- NCT02511626
- Where
- Switzerland
- Volunteers
- 1,267 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Chronic Urogenital Pain
Life-Stress Interview for Women With Chronic Urogenital Pain Conditions
The goal of this study is to test the efficacy, feasibility, and acceptability of providing an experiential assessment interview that targets health, and emotional and stressful experiences in a tertiary care setting specializing…
- Trial name
- NCT02286115
- Testing
- Life-Stress Interview
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Corewell Health East
Female Sexual Dysfunction, Multiple Sclerosis
Effects of Spinal Cord Injury on Female Sexual Response
The long term aims of this project are to 1) Understand the effect of varying degrees and levels of SCI and dysfunction(SCI/D)on females sexual response: 2) Identify the specific neuronal pathways involved in female sexual…
- Conditions
- Female Sexual Dysfunction, Multiple Sclerosis, Spinal Cord Injury
- Trial name
- NCT00142714
- Testing
- Sympathetic manipulation on sexual arousal in women
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pelvic Organ Prolapse
Effects of Pelvic Floor Muscle Training With & Without Hypopressive Exercises
Pelvic Organ Prolapse (POP) is a prevalent condition affecting women's quality of life due to the descent of pelvic organs caused by weak pelvic floor muscles (PFMs).
- Trial name
- NCT07440875
- Testing
- hypopressive excercises, pelvic training excercises
- Where
- Pakistan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Female Sexual Arousal Disorder
Examining Caffeine as a Treatment for Antidepressant-induced Arousal Dysfunction in Women
Antidepressants have negative effects on genital arousal function that hinder quality of life and jeopardize medication adherence.
- Trial name
- NCT05685407
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
Women's Health: Neoplasm of Breast, Menopause, Premature
Nurse-led Mind-body Intervention on Sexual Health for Breast Cancer Survivors
The goal of this clinical trial is to test the efficacy of a nurse-led psychoeducational sexual health intervention for young women breast cancer survivors. The main questions it aims to answer are: 1.
- Conditions
- Women's Health: Neoplasm of Breast, Menopause, Premature, Body Image, Sexual Dysfunction
- Trial name
- NCT06307470
- Testing
- EMBRACE (Empowerment through Mind and Body Reclamation After Cancer Experience)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Arkansas
Premature Ejaculation
A Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment of Premature Ejaculation
A phase I, single-center, double-blind, randomized, placebo-controlled, safety and pharmacokinetic study to evaluate systemic and local vaginal exposure to lidocaine and prilocaine and the metabolites, 2,6-dimethylaniline…
- Trial name
- NCT01184105
- Testing
- Intervention A, Intervention B
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plethora Solutions Ltd
Sexual Dysfunction
Efficiency of Tadalafil for Management of Female Sexual Dysfunction
comparative study between tadalafil versus placebo effect for the management of circumsized female
- Trial name
- NCT05266651
- Testing
- Tadalafil 5mg
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Kasr El Aini Hospital
HIV Infections, Mild Cognitive Impairment
Feasibility of the Mindfulness-Based Stress Reduction Intervention for Black Women Living With HIV Supplement
In our Supplement Aim we will conduct a two-arm randomized pilot test of the adapted intervention compared to a usual care control group among 30 African American/Black women with HIV (15/arm) to assess the feasibility and…
- Trial name
- NCT04984681
- Testing
- Mindfulness, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Alabama at Birmingham
Vulvodynia, Provoked Vestibulodynia
Biomodulation and Rehabilitation Interventions to tarGet Pelvic Health
This trial will provide evidence for the effective management of pain and pain-related domains among those who experience provoked vestibulodynia (PVD) using photobiomodulation (PBM) and multimodal physiotherapy (mPT) in a…
- Conditions
- Vulvodynia, Provoked Vestibulodynia, Dyspareunia
- Trial name
- BRIGHT (NCT06660212)
- Testing
- Photobiomodulation, Multimodal physiotherapy
- Where
- 2 sites in Canada
- Volunteers
- 240 people
- Sponsor
- University of Ottawa
Hypertension, Female Sexual Dysfunction
Comparative Effects of Nebivolol and Metoprolol on Female Sexual Function
Beta-blockers (BB) are an important treatment for high blood pressure and heart disease. However beta-blockers can cause sexual dysfunction (SD) and this common side effect limits successful use of this class of medications.
- Trial name
- NCT00995072
- Testing
- nebivolol and metoprolol succinate, metoprolol succinate and nebivolol
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- East Coast Institute for Research
Hypoactive Sexual Desire Disorder (HSDD), Low Libido
Acupuncture for Sexual Dysfunction
Female Sexual Dysfunction (FSD) affects up to 43% of women in the United States and Hypoactive Sexual Desire Disorder (HSDD) is the most common form. There is no standardized treatment for this condition.
- Conditions
- Hypoactive Sexual Desire Disorder (HSDD), Low Libido, Female Sexual Dysfunction (FSD)
- Trial name
- NCT02070029
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- TriHealth Inc.
Urinary Incontinence, Quality of Life
Effect of HIFEM® Treatment of Urinary Incontinence in Women in Primary Care. A Randomized Controlled Trial
Urinary incontinence (UI) is a condition with involuntary leakage of urine. UI has a significant impact on health related quality of life, poorer sleep quality and sexual function, reduced participation in social and physical…
- Conditions
- Urinary Incontinence, Quality of Life, Menopause, Mental Health Issue
- Trial name
- NCT06485167
- Testing
- HIFEM- chair
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Urologic Diseases, Patient Satisfaction
Developing a PROM for Recurrent Urinary Tract Infection
This study aims to develop and validate the first set of patient-reported outcome measures for recurrent urinary tract infection (UTI): the Recurrent UTI Symptom Scale and the Recurrent UTI Impact Questionnaire.
- Conditions
- Urologic Diseases, Patient Satisfaction, Pain, Chronic, Sexual Dysfunction
- Trial name
- NCT05086900
- Testing
- Non-interventional Cross-sectional Patient Reported Outcome Measure Development
- Where
- United Kingdom
- Volunteers
- 283 people
- Sponsor
- University of Reading
Premature (Early) Ejaculation
Comparative Evaluation of Safety and Efficacy of Dapoxetine, Silodosin, and Citalopram in the Management of Premature Ejaculation
This randomized controlled trial evaluated the comparative effectiveness and safety of four pharmacological treatments-Citalopram 20mg, Silodosin 4 mg, Dapoxetine 30 mg on demand, and Dapoxetine 30 mg daily-in men with premature…
- Trial name
- NCT07113145
- Testing
- Oral intake of medication
- Where
- Egypt
- Volunteers
- 450 people
- Sponsor
- Beni-Suef University
Lower Urinary Tract Dysfunction, Overactive Bladder Syndrome
Correlations of 3D Urethral and Paraurethral Sonographic Findings With Urodynamic Studies, Lower Urinary Tract Symptoms & Sexual Dysfunction in Female Patients With Lower Urinary Tract Symptoms.
The main purpose of this study is to get the urethra and pelvic sonographic imaging by 4D ultrasound examinations, and to correlate the sonographic findings with urodynamic variables, pad weights and LUTS.
- Trial name
- NCT01884753
- Where
- Taiwan
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital