Clinical trials: Female Sexual Dysfunction
Sexual Dysfunction, Postmenopausal Symptoms
Examination of the Effects of Pelvic Floor Exercises on Vaginal and Sexual Health in Postmenopausal Women.
The purpose of this study; To investigate the effects of pelvic floor muscle exercises on vaginal and sexual health in postmenopausal women.
- Conditions
- Sexual Dysfunction, Postmenopausal Symptoms, Pelvic Floor Muscle Weakness
- Trial name
- NCT06294197
- Testing
- Pelvic Floor Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hatice Gulsah Kurne
Dyspareunia
Fractional CO2 Laser Therapy Versus 4% Topical Lidocaine Gel for Dyspareunia in Breast Cancer Survivors
This trial seeks to determine if therapy with a CO2 laser to the vagina is more effective than lidocaine to the opening of the vagina before intercourse to reduce painful intercourse in women who are breast cancer survivors.
- Trial name
- BCLS (NCT03257670)
- Testing
- 4% Topical Lidocaine Gel, CO2RE fractional laser therapy
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Dyspareunia
Trigger Point Injections and Pelvic Rehabilitation for the Treatment of Pelvic Floor Myalgia and Sexual Pain
The purpose of this study is to evaluate which treatment option for pelvic floor pain allows for improved sexual function.
- Trial name
- NCT02022722
- Testing
- Trigger Point Injections Triamcinolone Acetonide, Bupivacaine Hydrochloride, Pelvic Rehabilitation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Cincinnati
Pain, Dyspareunia
Randomized Trial of Interrupted Versus Continuous Vaginal Closure of Anterior Repair With Mesh
Vaginal prolapse is a common condition that is treated with surgical correction. Recently surgeons have been using mesh to augment the repair of vaginal prolapse.
- Conditions
- Pain, Dyspareunia, Surgical Mesh
- Trial name
- NCT00676000
- Testing
- Interrupted vaginal closure, Continuous vaginal closure
- Volunteers
- 350 people
- Sponsor
- Brigham and Women's Hospital
Polycystic Ovary, Depression
The Effect of Polycystic Ovary Syndrome Phenotypes on Quality of Life and Sexual Function
This study was planned to examine whether different phenotypes of PCOS have an effect on quality of life, depression inventory and sexual function.
- Conditions
- Polycystic Ovary, Depression, Sexual Dysfunction
- Trial name
- PCOS (NCT06428786)
- Testing
- Female Sexual Function Index
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Dyspareunia, Pain
Effects of Myofascial Release With and Without Thiele Massage
Dysperunia is caused by chronic discomfort during sexual intercourse causing pain during vaginal intercourse.Sexual pain causes relationship decreasing quality of life following anxiety and depression.Myofascial techniques with…
- Conditions
- Dyspareunia, Pain, Quality of Life
- Trial name
- NCT05834088
- Testing
- Myofascial release techniques, Thiele massage
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Stroke, Spinal Cord Diseases
Use of tDCS Stimulation in Neurological and Gynaecological Conditions
The aim of the study is to test the effect of tDCS stimulation on upper and lower limb function in neurological patients and to reduce pain in gynaecological patients.
- Conditions
- Stroke, Spinal Cord Diseases, Nerve Root Disorder, Endometriosis
- Trial name
- tDCS (NCT06891690)
- Testing
- tDSC stimulation
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Endometriosis
SPIRIT EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Endometriosis-Associated Pain
The purpose of this study is to evaluate the long-term efficacy and safety of relugolix 40 milligram (mg) once daily co-administered with low-dose estradiol (E2) and norethindrone acetate (NETA) for up to 104 weeks on…
- Trial name
- NCT03654274
- Testing
- Relugolix, Estradiol/norethindrone acetate
- Where
- 169 sites in United States, Argentina and 18 more
- Volunteers
- 802 people
- Sponsor
- Myovant Sciences GmbH
Dyspareunia; Female
Physiotherapy Treatment With Capacitive Resistive Monopolar Radiofrecuency in Young Women With Dyspareunia
The hypothesis of this study is that capacitive-resistive monopolar radiofrecuency (CRMRF) with vaginal manual physiotherapy improves sexual health in young women suffering from dyspareunia (pain during sexual intercourse).
- Trial name
- [CRMRF] (NCT05844189)
- Testing
- Physical therapy modalities on pelvic floor (manual therapy), CRMRF
- Where
- Spain
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Escoles Universitaries Gimbernat
Menopause, Metabolic Syndrome
Low Sexual Desire and Metabolic Syndrome
Objective: To evaluate the prevalence of hypoactive sexual desire disorder (HSDD) in postmenopausal women diagnosed with metabolic syndrome (MS) and to compare it to that of a control group without MS.
- Conditions
- Menopause, Metabolic Syndrome, Hypoactive Sexual Desire Disorder, Obesity
- Trial name
- NCT02430987
- Testing
- Female sexual function index questionnaire, Evaluation of presence of metabolic syndrome, Evaluation of the body mass index
- Where
- Brazil
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Cervical Cancer, Female Sexual Dysfunction (FSD)
Biofeedback-Assisted Pelvic Floor Rehabilitation for Radiation-Induced Sexual Dysfunction in Cervical Cancer Survivors
This randomized controlled trial aims to evaluate the efficacy of biofeedback-assisted pelvic floor muscle training on radiation-induced sexual dysfunction in cervical cancer survivors following pelvic radiotherapy.
- Conditions
- Cervical Cancer, Female Sexual Dysfunction (FSD), Radiation Induced Pelvic Floor Muscle Dysfunction
- Trial name
- NCT07597083
- Testing
- Biofeedback-Assisted Pelvic Floor Muscle Rehabilitation, Conventional Pelvic Floor Muscle Training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Rectal Neoplasms, Sexual Dysfunction
Robotic Versus Laparoscopic Low Anterior Resection for Rectal Cancer
Prospective randomized trial comparing robotic versus laparoscopic Low anterior resection for rectal cancer. Primary endpoint: Compare urinary dysfunction between robotic and laparoscopic approach.
- Conditions
- Rectal Neoplasms, Sexual Dysfunction, Urinary Incontinence, Quality of Life
- Trial name
- RAR (NCT03209076)
- Testing
- Robotic, Laparoscopic
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Perimenopause, Perimenopause-Related Depression
Intra Ovarian Muse Cell Injection for Perimenopause Symptom Relief and Ovarian Function Restoration (MUSE-OVARY)
This observational study examines the safety and effects of injecting Muse cells (a type of naturally occurring stem like cells found in adult tissues such as fat or bone marrow) directly into the ovaries of women aged 28 to 70…
- Conditions
- Perimenopause, Perimenopause-Related Depression, Premature Ovarian Insufficiency, Premature Ovarian Failure (POF)
- Trial name
- MUSE-OVARY (NCT07511660)
- Where
- Mexico
- Volunteers
- 12 people
- Sponsor
- Healing Hope International
Prostate Cancer
IONM During Radical Prostatectomy
At present, the preferred treatment for patients with prostate cancer is still radical prostatectomy. Postoperative patients often face some complications, the most common complications include urinary incontinence and erectile…
- Trial name
- NCT06950216
- Testing
- IONM
- Volunteers
- 40 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Primary Sjögren Syndrome, Vaginitis Candida
Sjögren and Gynecologic Considerations
Sjögren's syndrome is an autoimmune disorder characterized by glandular and extra-glandular manifestations. It is called primary Sjögren's syndrome (pSS) in absence of another connective tissue disease.
- Conditions
- Primary Sjögren Syndrome, Vaginitis Candida, Vaginitis, Sexual Dysfunction
- Trial name
- NCT05670535
- Testing
- Visual analogue scale (VAS) for dyspareunia, Visual analogue scale (VAS) for vaginal dryness, The European League Against Rheumatism Sjögren's Syndrome Disease Activity Index (ESSDAI)
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Ankara City Hospital Bilkent
Sexual Dysfunction
Efficacy of Exercise for Sexual Side Effects of Antidepressants
The major aim of the this study is to replicate findings of previous research that examined the effects of acute exercise on sexual arousal in women in a novel population, namely, women taking antidepressants of the selective…
- Trial name
- NCT01189825
- Testing
- Exercise
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Texas at Austin
Dyspareunia
Effectiveness of Radiofrequency Combined With Ultrasound for the Treatment of Postpartum Dyspareunia
The objective of this community-based, non-randomized, quasi-experimental study is to assess the effectiveness of BTL EXILIS technology-based on combined radiofrequency and ultrasound-in women of childbearing age from an…
- Trial name
- NCT07504991
- Testing
- Combining radiofrequency and ultrasound. BTL Exilis
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Lower Urinary Tract Symptoms
Bladder Wall Blood Perfusion Pattern and Sexual Dysfunction in Female Patients With Lower Urinary Tract Symptoms, and the Association of That Perfusion Pattern and Therapeutic Efficacy of Antimuscarincs for Female Overactive Bladder Syndrome.
Overactive bladder syndrome (OAB) affects around 17 % of female population. However, the etiology of OAB is complicated and unclear in many aspects.
- Trial name
- NCT01282840
- Testing
- Tolterodine SR
- Where
- Taiwan
- Volunteers
- 676 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Endometriosis
Endometriosis Pelvic Pain Interdisciplinary Cohort Data Registry
The purpose of this data registry is to prospectively collect data from patients referred to an interdisciplinary clinic for pelvic pain and endometriosis to investigate long-term patient outcomes, prognosis, predictors, causes…
- Trial name
- EPPIC (NCT02911090)
- Testing
- Data Registry
- Where
- Canada
- Volunteers
- 5,000 people
- Sponsor
- BC Women's Hospital & Health Centre
Female Sexual Dysfunction (FSD), Pelvic Floor Muscle Training
Effects of Extracorporeal Shockwave Therapy Versus Pulsed Electromagnetic Field Therapy in Females With Sexual Dysfunction.
This is a prospective, three-arm, parallel-group, assessor-blinded randomized controlled trial designed to compare the effectiveness of extracorporeal shockwave therapy (ESWT) combined with pelvic floor muscle training (PFMT)…
- Conditions
- Female Sexual Dysfunction (FSD), Pelvic Floor Muscle Training, Shock Wave, Pulsed Electromagnetic Therapy
- Trial name
- NCT07584174
- Testing
- low-intensity extracorporeal shockwave therapy, Pulsed electromagnetic field stimulation, Pelvic floor muscle training
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University