Clinical trials: Female Urinary Incontinence
Urgency Urinary Incontinence
Investigation of Brain Mechanisms Involved in the Urinary Continence Mechanism Associated With Aging
Urge urinary incontinence (UUI) is a common problem in older people which vastly reduces quality of life, yet the cause and mechanism of disease are not well understood.
- Trial name
- NCT04599088
- Testing
- Brain functional MRI with simplified urodynamics
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Postoperative Urinary Tract Infection, Pelvic Organ Prolapse
Gentamicin Intravesical Efficacy for Infection of Urinary Tract
Urinary tract infection (UTI) is a common problem after surgery for pelvic organ prolapse and stress urinary incontinence. This prospective, randomized, single-masked (subject), two-parallel armed study aims to determine the…
- Conditions
- Postoperative Urinary Tract Infection, Pelvic Organ Prolapse, Stress Urinary Incontinence
- Trial name
- GIVEIT (NCT04246996)
- Testing
- gentamicin sulfate, Catheter clamping only
- Where
- 2 sites in United States
- Volunteers
- 370 people
- Sponsor
- Kaiser Permanente
Urinary Incontinence
Assessment of Two Postoperative Techniques Used to Predict Voiding Efficiency After Gynecologic Surgery
After gynecologic surgery, it may be difficult to void (urinate). This problem is usually short-term with normal function returning within a few days to a few weeks.
- Trial name
- NCT00392210
- Testing
- Voiding Trial
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Urinary Incontinence
A Pilot Clinical Trial of TENA Identifi in the Nursing Home Setting
The purpose of this study is to prospectively compare a standard of care manual toileting protocol (e.g., "check and change" strategy) to toileting patterns recorded by the TENA Identifi system in identifying incontinence…
- Trial name
- NCT03209570
- Testing
- Care planning using TENA Identifi sensor wear data, Care planning without using TENA Identifi sensor wear data
- Where
- 5 sites in United States
- Volunteers
- 49 people
- Sponsor
- Insight Therapeutics, LLC
Female Stress Incontinence
Continence Pessary Versus Disposable Intravaginal Device Trial
This is a multi-centered randomized controlled trial of women with stress urinary incontinence or stress predominant mixed urinary incontinence who desire non-surgical therapy.
- Trial name
- NCT03174431
- Testing
- Continence Pessary, Poise Impressa (Disposable Intravaginal Device)
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Ohio State University
Urinary Incontinence
Consumer Evaluation of Intermittent Catheter Product Modifications
This study aims to collect feedback from hydrophilic intermittent catheter end-users to assess user acceptance of the test hydrophilic intermittent catheter and generate evidence to support commercial marketing objectives.
- Trial name
- NCT04619992
- Testing
- Currently marketed Hydrophillic Intermittent Catheter, Test Hydrophilic Intermittent Catheter
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Hollister Incorporated
Metrorrhagia, Urinary Incontinence
Controlled Trial of Tele-Support and Education for Womens Health Care in CBOCs
VA community-based outpatient clinics (CBOCs) typically serve only a small number of women Veterans, and generally do not have the women's health care resources that are available in larger settings.
- Conditions
- Metrorrhagia, Urinary Incontinence, Remote Consultation, Videoconferencing
- Trial name
- WH CREATE P4 (NCT01918072)
- Testing
- Clinical innovation
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- VA Office of Research and Development
Mixed Urinary Incontinence, Stress Urinary Incontinence
The SLIM Study: Sling and Botox® Injection for Mixed Urinary Incontinence
This double-blind randomized controlled trial seeks to find a better treatment for women with mixed urinary incontinence (both stress and urgency incontinence).
- Conditions
- Mixed Urinary Incontinence, Stress Urinary Incontinence, Urgency Incontinence
- Trial name
- NCT02678377
- Testing
- OnabotulinumtoxinA (Botox ®) Injections, Saline Injections
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Northwestern University
Stress Urinary Incontinence
Study to Assess Enobosarm (GTx-024) in Postmenopausal Women With Stress Urinary Incontinence
GTx-024 is an orally bioavailable and tissue-selective nonsteroidal selective androgen receptor modulator (SARM) that has demonstrated androgenic and anabolic activity and is currently being evaluated as a potential treatment for…
- Trial name
- ASTRID (NCT03241342)
- Testing
- GTx 024
- Where
- 62 sites in United States
- Volunteers
- 491 people
- Sponsor
- GTx
Stress Urinary Incontinence
Effect of Peri-Urethral Stimulation on Intra-Urethral Pressure
The purpose of this early feasibility prospective study is to gain initial understanding of the effect of acute peri-urethral neurostimulation on the perineal nerves on intra-urethral pressure.
- Trial name
- NCT05900570
- Testing
- Urodynamic testing with and without pudendal nerve stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Corewell Health East
Stress Urinary Incontinence
Artificial Urinary Sphincter Clinical Outcomes
To evaluate the AMS 800 Artificial Urinary Sphincter (AUS) in men with primary stress urinary incontinence as measured by pad weight tests.
- Trial name
- AUSCO (NCT04088331)
- Testing
- AMS 800 Artificial Urinary Sphincter
- Where
- 18 sites in United States, Australia
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Erectile Dysfunction, Overactive Bladder
Mirabegron For Erectile Dysfunction
The only class of oral erectile dysfunction (ED) medication on the market are the phosphodiesterase Type 5 inhibitors (PDE5i). This pilot study is being done to evaluate the effect of Mirabegron, an oral beta-3 adrenergic…
- Conditions
- Erectile Dysfunction, Overactive Bladder, Urinary Incontinence
- Trial name
- NCT02916693
- Testing
- Mirabegron
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Urinary Incontinence, Prostate Cancer
Perioperative Post-Prostatectomy Incontinence Home Telehealth Program
Many men develop urine leakage after prostate cancer surgery. Usually it is temporary, but pelvic floor muscle training and exercise (including urine control strategies) have been shown to reduce the time to regaining urine…
- Trial name
- ProsTel (NCT01960998)
- Testing
- Pelvic Floor Muscle Training, Perioperative Care and Wetness Management
- Where
- 3 sites in United States
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Urinary Incontinence
A Multi-Center Trial of Botox for Severe Urge Urinary Incontinence
The purpose of the study is to determine how effective Botox is in reducing the amount of urine leaked and which dose of Botox is more effective and safe in those who have urinary urge incontinence.
- Trial name
- NCT00345332
- Testing
- Botox
- Where
- 3 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Overactive Bladder
Safety and Effectiveness of a Non-invasive Neuromodulation Device on Urgency Urinary Incontinence in Overactive Bladder
The purpose of this study is to evaluate the change from baseline between the active and sham treatment groups in the treatment of urgency (urinary) incontinence episodes (leaks).
- Trial name
- Beacon (NCT01369485)
- Testing
- (VERV™ System)
- Where
- 14 sites in United States
- Volunteers
- 163 people
- Sponsor
- Ethicon Endo-Surgery
Overactive Bladder, Urge Incontinence
Pivotal Study of eCoin for Overactive Bladder With Urgency Urinary Incontinence
This trial is a prospective, multicenter, single-arm study of the safety and effectiveness of eCoinTM tibial nerve stimulation in subjects having overactive bladder (OAB) with urgency urinary incontinence (UUI).
- Conditions
- Overactive Bladder, Urge Incontinence, Incontinence, Urinary, Urinary Urge Incontinence
- Trial name
- NCT03556891
- Testing
- eCoin Tibial Nerve Stimulation
- Where
- 15 sites in United States
- Volunteers
- 133 people
- Sponsor
- Valencia Technologies Corporation
Female Stress Urinary Incontinence
Treatment of Stress Urinary Incontinence Via Smartphone
The purpose of this study is to determine whether treatment of stress urinary incontinence (SUI) via smartphone is effective.
- Trial name
- NCT01848938
- Testing
- Smartphone treatment with PFMT
- Where
- Sweden
- Volunteers
- 123 people
- Sponsor
- Umeå University
Stress Urinary Incontinence
The Altis® Single Incision Sling System for Female Stress Urinary Incontinence Study
An international, multi-center, single arm, prospective clinical study designed to assess the safety and efficacy of the Coloplast Altis single incision sling system for females with stress urinary incontinence (SUI).
- Trial name
- NCT01272284
- Testing
- Altis® Single Incision Sling System (SIS)
- Where
- 17 sites in United States, Canada
- Volunteers
- 113 people
- Sponsor
- Coloplast A/S
Urinary Incontinence, Stress
Trans-obturator Mid-urethral Sling and the Single-incision Sling in Women With Stress Urinary Incontinence
Mid-urethral slings (MUS) now represent a gold standard in the treatment of female stress urinary incontinence (SUI). Second generation trans-obturator slings (TOT) have proven to be as effective as retropubic tension-free…
- Trial name
- NCT02506309
- Testing
- TOT - inside-out trans-obturator tape/sling, SIS - Innovative fixation single incision sling
- Volunteers
- 168 people
- Sponsor
- Brno University Hospital
Stress Urinary Incontinence
Time Interval Between TVT and First Void (TIBT) Study
The primary aim of this study is to compare, in women undergoing tension-free vaginal tape (TVT) insertion under sedation and local anaesthetic infiltration, the time interval of first void following surgery between a group of…
- Trial name
- TIBT (NCT02443987)
- Testing
- Intravenous fluid
- Where
- 2 sites in United Kingdom
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust