Clinical trials: Femoral Hip Fracture
Hip Fracture
Effects of Bisphosphonates and Nutritional Supplementation After a Hip Fracture
The study hypothesis is that nutritional supplementation together with bisphosphonates have a better preserving effect on bone mineral density (BMD) after hip fracture than bisphosphonates alone and that nutritional…
- Trial name
- NCT01950169
- Testing
- Risedronate, Nutritional supplement, Calcium and vitamin D3
- Where
- Sweden
- Volunteers
- 79 people
- Sponsor
- Karolinska Institutet
Hip Fractures, Anesthesia
Does Optimized General Anesthesia Care Reduce Postoperative Delirium?
Postoperative delirium occurs in up to 65% of elders undergoing surgery for repair of a hip fracture and this complication is independently associated with increased morbidity, mortality, length of hospital stay, and placement in…
- Conditions
- Hip Fractures, Anesthesia, Delirium
- Trial name
- OPCare (NCT02604459)
- Testing
- cerebral oximeter (Fore-Sight), depth of anesthesia monitor (BIS), BP management
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- University of Missouri-Columbia
Muscle Wasting (Atrophy) After Hip Fracture Surgery
Study of Efficacy and Safety of Bimagrumab in Patients After Hip Fracture Surgery
The purpose of this study was to assess if bimagrumab is safe and effective in patients with muscle wasting (atrophy) after hip fracture surgery.
- Trial name
- NCT02152761
- Testing
- bimagrumab
- Where
- 53 sites in United States, Argentina and 17 more
- Volunteers
- 251 people
- Sponsor
- Novartis Pharmaceuticals
Delirium
Supporting the Health of Adults Undergoing Orthopedic Surgery During the Recovery Period
Delirium (acute confusion) is a highly prevalent condition among hospitalized elders with substantial morbidity within the hospital and beyond.
- Trial name
- SHARP (NCT00586196)
- Testing
- donepezil
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hip Fracture
PUSH Plus Protein Pilot for Hip Fracture Patients
Hip fracture is a common problem among older individuals. The goal of current standard of care after hip fracture is to achieve independent, household ambulation 2-3 months after surgery, yet decreased functional ability…
- Trial name
- NCT03410823
- Testing
- PUSH, Protein, Nutrition
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Femoral Neck Fractures, Hip Fractures
Ultrasound-guided Femoral Nerve Blocks in Elderly Patients With Hip Fractures
The purpose of this study is to determine if ultrasound guided femoral nerve blocks (localized anesthesia in the upper thigh) provide effective pain relief in adult patients with hip fractures in the emergency department and to…
- Trial name
- FNB (NCT01701414)
- Testing
- Femoral nerve block: 25 mL of 0.5% bupivacaine
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Rhode Island Hospital
Hip Fractures, Delirium
Post-Operative Delirium in Elderly Surgical Patients
This research is being done to see what effects sedative drugs during surgery have on peoples' thinking processes after they wake up.
- Trial name
- STRIDE (NCT00590707)
- Testing
- Deeper sedation, Moderate sedation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Johns Hopkins University
Femoral Fracture (Proximal)
DePuy Trochanteric (ATN) Nailing Clinical Outcomes Trial
The purpose of this study is to monitor trochanteric fracture healing and review the performance of the ATN system.
- Trial name
- ATN (NCT00546429)
- Testing
- Intramedullary nailing
- Where
- 4 sites in United States
- Volunteers
- 62 people
- Sponsor
- DePuy Orthopaedics
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Hip Fractures
Computer-Assisted Fixation of Trochanteric Femur Fractures
The purpose of this study is to assess whether the Stryker© ADAPT™ augmented-reality platform can assist surgeons in optimizing placement of the lag screw component of the Stryker© Gamma™ cephalomedullary nail.
- Trial name
- NCT04528459
- Testing
- Stryker© ADAPT™ platform, Traditional fluoroscopy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Columbia University
Osteoporosis, Osteopenia
A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.
The purpose of this study is to determine whether in postmenopausal women with low bone mineral density, the mean percent change in total hip BMD in subjects receiving denosumab is not less than that observed in subjects…
- Trial name
- NCT00330460
- Testing
- Alendronate, Denosumab
- Volunteers
- 1,189 people
- Sponsor
- Amgen
Hip Fractures, Blood Loss
Safety and Efficacy of Oral TXA in Reducing Blood Loss and Transfusion in Hip Fractures
The primary objective of this study is to assess the safety and efficacy of Tranexamic acid (TXA) in reducing blood loss and transfusion requirements for patients with osteoporotic hip fractures.
- Trial name
- NCT02908516
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Yale University
Hip Fracture
Ultrasound Guided Pain Control Versus Standard Treatment in Emergency Department HIP Fracture Patients
Hip Fracture (HFx) is a painful injury that is often treated in the Emergency Department (ED) with intravenous opiates. However, this class of medications may cause deleterious side effects.
- Trial name
- NCT01904071
- Testing
- UFNB (Ultrasound guided femoral nerve block), UFIB (Ultrasound Guided Fascia Iliaca Compartment Block), IVMS (IV Morphine)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Antonios Likourezos
Femoral Neck Fractures
Using Alternative Implants for the Surgical Treatment of Hip Fractures (The FAITH Study)
Each year, hip fracture, an injury that can impair independence and quality of life, occurs in about 280,000 Americans and 36,000 Canadians.
- Trial name
- NCT00761813
- Testing
- Open reduction internal fixation (ORIF) with single sliding hip screw, ORIF with multiple cancellous screws
- Where
- 32 sites in United States
- Volunteers
- 1,108 people
- Sponsor
- University of Minnesota
Femur Neck Fracture
Effect of Teriparatide on Hip Fracture Healing
The purpose of this study is to see whether teriparatide, given for 6 months versus placebo, will improve the healing of hip (femoral neck) fractures that are repaired during surgery using certain types of orthopedic screws.
- Trial name
- NCT01473589
- Testing
- Teriparatide, Calcium supplementation, Vitamin D supplementation
- Where
- 92 sites in United States, Australia and 17 more
- Volunteers
- 122 people
- Sponsor
- Eli Lilly and Company
Hip Fractures, Hip Arthropathy
Optimizing Cerebral Autoregulation During Surgery
The purpose of this study is to conduct a pilot trial to determine the feasibility, safety, and potential efficacy of targeting mean arterial blood pressure (MAP) within the limits of cerebral autoregulation during surgery…
- Conditions
- Hip Fractures, Hip Arthropathy, Surgery, Delirium
- Trial name
- NCT05308290
- Testing
- Blood pressure management according to cerebral autoregulation, Blood pressure management according to usual care
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Johns Hopkins University
Osteoarthritis, Traumatic Arthritis
Actis Total Hip System 2 Year Follow-up
Two-year (2 year) information regarding the performance of the commercially available Actis™ Total Hip System in order to obtain and evaluate the clinical outcomes on a series of cementless primary total hip arthroplasty (THA)…
- Conditions
- Osteoarthritis, Traumatic Arthritis, Rheumatoid Arthritis, Congenital Hip Dysplasia
- Trial name
- Actis14014 (NCT02783274)
- Testing
- Actis Total Hip System
- Where
- 9 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- DePuy Orthopaedics
Hip Fractures
Evaluation of TXA Prior to Surgery in the Geriatric Hip Fracture Population
The overall design of the study is a prospective, double-blinded, randomized study in the geriatric hip fracture population comparing those who receive intravenous tranexamic acid prior to incision to those who receive a placebo.
- Trial name
- TAHFT (NCT03923959)
- Testing
- Tranexamic Acid Injectable Solution
- Where
- United States
- Volunteers
- 283 people
- Sponsor
- Lancaster General Hospital
Intracapsular Fracture of Femur, Femoral Neck Fractures
Hip Fracture Exparel Administration Trial Capsule During Hemiarthroplasty
This study will examine the efficacy of Liposomal Bupivacaine (Exparel) in hip fracture patients undergoing hip hemiarthroplasty for femoral neck fractures through a posterior approach.
- Conditions
- Intracapsular Fracture of Femur, Femoral Neck Fractures, Hip Hemiarthroplasty
- Trial name
- HEAT (NCT03502018)
- Testing
- Bupivacaine liposome, Saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Maimonides Medical Center
Hip Fracture, Pressure Ulcer
Polyurethane Foam on the Sacrum for Prevention
The aim of the present study is to assess whether the application of a new hydrocellular polyurethane foam multilayer dressing shaped for the sacral area (MSP) in addition to standard care reduces the rate of pressure sores (PU)…
- Trial name
- NCT02692482
- Testing
- hydrocellular polyurethane foam multilayer dressing, standard care
- Where
- Italy
- Volunteers
- 359 people
- Sponsor
- Istituto Ortopedico Rizzoli