Clinical trials: Femoral Hip Fracture
Delirium - Postoperative
Effects of PNB Timing on Postoperative Delirium for Hip Fracture
Hip fracture is a common cause of hospitalization in older adults and is associated with substantial pain and a high risk of delirium.
- Trial name
- NCT07856108
- Testing
- Peripheral Nerve Block for Hip Fracture
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Rheumatoid Arthritis, Osteoarthritis
G7 BiSpherical Acetabular Shell PMCF Study
The primary objective of this study is to obtain implant survivorship and clinical outcomes data for the commercially available G7 BiSpherical Acetabular Shell.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Noninflammatory Degenerative Joint Disease, Avascular Necrosis
- Trial name
- NCT03266874
- Where
- 5 sites in France, Germany and 2 more
- Volunteers
- 160 people
- Sponsor
- Zimmer Biomet
Hip Fracture
Ultrasound Guided Femoral Nerve Block
The goal of the study is to evaluate whether pain control achieved by Ultrasound Guided Femoral Nerve Blockade (USFNB) is equal in efficacy to standard pain management practice of parenteral injection of opioid pain medication in…
- Trial name
- NCT02381717
- Testing
- ultra-sound guide, bupivacaine, morphine
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Beth Israel Deaconess Medical Center
Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck
Z1 Hip System: Post-Market Clinical Follow Up Study
The objectives of this study are to confirm the early to mid- term safety, performance, and clinical benefits of the Z1 Femoral Hip System in hemi- and primary total hip arthroplasty.
- Conditions
- Hip Osteoarthritis, Acute Traumatic Fracture of the Femoral Head or Neck, Avascular Necrosis of the Femoral Head
- Trial name
- NCT07104279
- Testing
- Z1 Femoral Hip System
- Where
- 5 sites in United States
- Volunteers
- 300 people
- Sponsor
- Zimmer Biomet
Hip Fractures, Undisplaced Intracapsular Hip Fracture
Fixation Versus Arthroplasty for Undisplaced Intracapsular Fractures
In England each year over 70,000 people fracture their hip. Most of these patients are elderly females with the fracture occurring after a simple trip or stumble.
- Trial name
- NCT02996383
- Testing
- Internal fixation, Cemented Hemiarthroplasty
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Peterborough and Stamford Hospitals NHS Foundation Trust
Hip Fractures
Nutritional Optimization and Bone Health Management for Older Adults Undergoing Hip Fracture Surgery
The overall objective of this pilot study is to test a comprehensive nutritional intervention in elderly patients diagnosed with hip fracture, which the study team believe will reduce functional decline, morbidity and mortality.
- Trial name
- NCT05971173
- Testing
- Juven, Centrum Silver 50+
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Hip Osteoarthritis, Hip Arthropathy
Post Market Clinical Follow-up of EUROSTEM Femoral Stem
EUROSSTEM is intended for use in primary and revision total hip replacement surgery. Hip replacement is intended to provide increased patient mobility and reduce pain by replacing the damages hip joint articulation in patients…
- Conditions
- Hip Osteoarthritis, Hip Arthropathy, Hip Arthritis, Hip Necrosis
- Trial name
- NCT04995822
- Testing
- hip arthroplasty
- Where
- 9 sites in France
- Volunteers
- 131 people
- Sponsor
- EUROS
Intertrochanteric Femoral Fracture
Risk Factors for Intertrochanteric Femoral Fractures With Concomitant Lateral Wall Involvement in Elderly Women
This study aims to better understand the factors that increase the risk of a special type of hip fracture in older women, known as intertrochanteric femoral fractures with lateral wall involvement.
- Trial name
- Fracture (NCT07196982)
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 49 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Postoperative Cognitive Dysfunction, Hip Fractures
The Comparison of Cognition, Depression and Anxiety, and Quality of Life After Hip Fracture Surgery Under General or Regional Anesthesia
Postoperative cognitive dysfunction is a relatively common in elderly patients after hip surgery, but exact mechanism of its onset is still unclear as well as contributing factors.
- Conditions
- Postoperative Cognitive Dysfunction, Hip Fractures, Depression, Anxiety, Quality of Life
- Trial name
- NCT04518839
- Volunteers
- 140 people
- Sponsor
- University of Zagreb
Femoral Neck Fracture
Allogeneic Mesenchymal Stromal Cells in Elderly Patients With Hip Fracture
Prospective, unicenter, randomized, open-label, single-dose, two-arms blinded assessor pilot study. Thirty-two (32) elderly patients with hip fracture will be randomized to one of the two treatment-arms (Xcel-MT-osteo-beta or…
- Trial name
- NCT02630836
- Testing
- XCEL-MT-OSTEO-BETA, Surgical treatment
- Sponsor
- Banc de Sang i Teixits
Osteoarthritis, Avascular Necrosis
Post-market Surveillance Study With the HYPERION Hip Endoprosthesis System in Defect Reconstruction
The study is a multi-center, prospective, non-controlled, consecutive cohort post market surveillance study. The objective of this study is to obtain survival and clinical outcome data on the Hyperion® system in primary and…
- Conditions
- Osteoarthritis, Avascular Necrosis, Rheumatoid Arthritis, Functional Deformities
- Trial name
- NCT03382665
- Where
- 3 sites in Germany
- Volunteers
- 70 people
- Sponsor
- Zimmer Biomet
Hip Fracture
Better Hips- Better Function
The focus of this project are elderly people who have experienced hip fracture and need at least two weeks rehabilitation after discharge from hospital.
- Trial name
- NCT02815254
- Testing
- High intensity functional exercise, Low intensity functional exercise
- Where
- Norway
- Volunteers
- 105 people
- Sponsor
- Oslo Metropolitan University
Intertrochanteric Fractures, Hip Fractures
Liposomal Bupivacaine Fascia Iliaca Block for Perioperative Sleep Quality in Elderly Patients With Intertrochanteric Fracture
Older adults with hip fracture often experience severe pain before and after surgery. This pain can cause anxiety and poor sleep, and may increase the risk of postoperative delirium (sudden confusion after surgery).
- Conditions
- Intertrochanteric Fractures, Hip Fractures, Sleep Disturbance, Postoperative Delirium
- Trial name
- NCT07892859
- Testing
- Liposomal Bupivicaine, Saline Solution (NaCl 0,9%)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Li Xiaoyuan
Inguinal Hernia, Pelvic Fracture
Corona Mortis in Patients Undergoing TEP for Inguinal Hernia
This study aim to describe the presence, type and size of Corona mortis (CMOR) in patients undergoing total extraperitoneal (TEP) inguinal hernia repair procedures.
- Conditions
- Inguinal Hernia, Pelvic Fracture, Acetabular Fracture, Bleeding
- Trial name
- NCT04303442
- Testing
- TEP
- Where
- Bulgaria
- Volunteers
- 300 people
- Sponsor
- Sofia Med Hospital
Hip Fracture
Comparison of Intraoperative- Postoperative Effects of Pericapsular Nerve Block and Fascia Iliaca Block in Hip Fracture
The aim of this study is to apply pericapsular nerve group (PENG) block or fascia iliaca plan block using ultrasonography to patients who will undergo hip fracture surgery, while giving sitting position before spinal anaesthesia…
- Trial name
- NCT06001996
- Testing
- Pericapsular nerve group (PENG) block, Suprainguinal fascia iliaca plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Hip Fracture, Postoperative Recovery
Total Intravenous Versus Inhalational Anesthesia in Patients Undergoing Hip Fracture Surgery
This prospective observational study aims to compare total intravenous anesthesia (TIVA) with sevoflurane-based inhalational anesthesia in patients aged 65 years and older undergoing hip fracture surgery under general anesthesia.
- Trial name
- NCT07860996
- Testing
- Propofol-based Total Intravenous Anesthesia, Sevoflurane-based Inhalational Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Hip Fracture , Postoperative Mortality
Clinical Data-Driven AI Model for Mortality Prediction After Hip Fracture
Hip fractures are a major cause of morbidity and mortality, particularly in elderly patients. Accurate prediction of postoperative mortality is critical for risk stratification and clinical decision-making.
- Trial name
- NCT07495527
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Hip Fractures
'Rehabilitation for Life'
Despite implementing hospital quality programs after hip fracture surgery older adults often experience a decline in the level of physical function, reduced quality of life; and the mortality and readmission rates are high.
- Trial name
- NCT04424186
- Testing
- 'Rehabilitation for Life', Usual care and rehabilitation
- Where
- Denmark
- Volunteers
- 339 people
- Sponsor
- Kolding Sygehus
Hip Fractures, Analgesia
Comparison of the Efficiency of Femur Nerve Block and Intravenous Analgesia Treatment in Hip Fracture Patients
It is well-established that hip fractures impose a significant medical, socioeconomic, and financial burden. In the elderly population, the associated mortality and morbidity are particularly pronounced: within one year following…
- Conditions
- Hip Fractures, Analgesia, Femoral Nerve
- Trial name
- NCT06862154
- Testing
- IV Analgesia- Fentanyl, Femoral Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Marmara University
Intertrochanteric Fractures
Internal Fixation or Joint Replacement Therapy for Aged Hip Fracture Patients
To evaluate the efficacy and safety of internal fixation or arthroplasty for hip fracture patients over 75 years of age with multiple medical complications through the operation time, intraoperative bleeding, time to start weight…
- Trial name
- NCT03407131
- Testing
- Joint replacement surgery, Intramedullary nail fixation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
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