Clinical trials: Femoral Hip Fracture
Proximal Femoral Fracture
Proximal Femoral Fractures - Patient Population, Risk Factors, Surgical Performance and Outcome
Proximal femoral fractures are a typical pathology in elderly patients after a low-energy trauma. This study analyses preexisting risk factors for proximal femoral fractures as well as for failing to reach the previous functional…
- Trial name
- ProFi (NCT03768622)
- Testing
- surgery for pertrochanteric femoral fracture, surgery for femoral neck fracture
- Where
- Switzerland
- Volunteers
- 2,906 people
- Sponsor
- University Hospital, Basel, Switzerland
Hip Fractures, Anesthesia
Validation of Nexfin Cardiac Output in Elderly Patients With Hip Fracture
Measurement of how much blood the heart pumps may be useful in guiding how much intravenous fluid to give patients during surgery.
- Trial name
- NCT01474824
- Where
- 2 sites in United Kingdom
- Volunteers
- 6 people
- Sponsor
- University of Nottingham
Femoral Neck Fracture
Perioperative Analgesia by Femoral Perineural Catheter for Femoral Neck Fracture - Study KTcol
Therapeutic essay of phase IV, monocentric, prospective, randomized, in double-blind during 48 hours(then simple-blind),controlled by placebo.
- Trial name
- KTcol (NCT01052974)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Bone Neoplasm of Hip (Diagnosis), Orthopedic Disorder
Evaluation of the Ability of CT-based Finite Element Analysis (CTFEA) to Predict Fractures in Patients With Metastases: a Randomized Controlled Study.
Patients with metastases to proximal femur, who are evaluated fr the risk of pathologic fracture in order to decide on preventive fixation vs follow-up constitute the study population. The patients will be randomized in two arms.
- Conditions
- Bone Neoplasm of Hip (Diagnosis), Orthopedic Disorder, Bone Metastases, Proximal Femoral Metaphyseal Abnormality
- Trial name
- ZYCTFEA (NCT03453905)
- Testing
- CTFEA, Conventional decision algorithm
- Volunteers
- 162 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Hip Fracture, Hip Fracture Surgeries
External Validation of Ten Prediction Models for 30-day Mortality Following Hip Fracture
This study aims to externally validate ten existing prediction models with a low risk of bias for 30-day mortality following hip fracture.
- Trial name
- PROTECT (NCT06961253)
- Where
- Netherlands
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- JointResearch
Osteoporotic Fracture of Femur, Osteoarthritis, Hip
Study of Parameters of Osteosarcopenia in Patients With Hip Fracture
The study aims to assess the adequacy of a set of clinical and laboratory investigations for identifying the osteosarcopenia status in patients undergoing a hip replacement for a fragility fracture of the femoral neck.
- Trial name
- NCT04730622
- Testing
- SARC-F questionnaire, Bone tissue histology, Muscle tissue histology
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Ortopedico Rizzoli
Minimum Effective Dose of Local Anaesthetic With Fentanyl
Minimum Effective Intrathecal Dose of Local Anaesthetic With Fentanyl for Fractured Neck of Femur(Dose Finding Study).
Fractured neck of femur (FNF) is a common cause of admission to hospital in elderly patients with multiple comorbidities. Anaesthetic management of this patient group is extremely challenging.Neuraxial anaesthesia with minimum…
- Trial name
- NCT01922622
- Where
- Ireland
- Volunteers
- 33 people
- Sponsor
- Cork University Hospital
Slipped Capital Femoral Epiphysis
Management of Slipped Capital Femoral Epiphysis (SCFE) on Top of Fixed Fracture Neck of Femur Case Report.
Slipped Capital Femoral Epiphysis (SCFE) on Top of Fixed Fracture Neck of Femur managed by subtrochanteric valgus osteotomy
- Trial name
- SCFE (NCT05758051)
- Testing
- subtrochanteric valgus osteotomy
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Assiut University
Fractured Neck of Femur, Postoperative Pain
Postoperative Analgesia for Fractured Neck of Femur With Periarticular Infiltration of Local Anaesthetic
The purpose of this study is to determine that periarticular levobupivacaine infiltration after surgical fixation of fractured neck of femur will improve the early postoperative pain sensation.
- Trial name
- NCT02057601
- Testing
- Levobupivacaine infiltration group
- Where
- Ireland
- Volunteers
- 37 people
- Sponsor
- Cork University Hospital
Hip Fracture
Fascia Iliaca Compartment Blockade as Analgesia for Hip Fractures in the Acute Phase
To evaluate the analgesic potential of an neural blockade (Fascia iliaca compartment) with local anaesthetics in patients with hip fracture immediately after arrival in the emergency department.
- Trial name
- NCT00162630
- Testing
- Fascia Iliaca Compartment Blockade
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Postoperative Delirium, Hip Fractures
The Southeast and East Asian Post-Operative Delirium (SEAPOD) Study
The specific aim of the study will be to investigate the incidences and risk factors for postoperative delirium (POD) after hip fracture surgery in elderly patients aged ≥ 65 years in five different Southeast and East Asian…
- Trial name
- NCT04999891
- Testing
- Neurocognitive tests
- Where
- 13 sites in Japan, Malaysia and 3 more
- Volunteers
- 1,000 people
- Sponsor
- National University Hospital, Singapore
Femoral Neck Fractures, Postoperative Complications
Postoperative Recovery in Elderly Patients Undergoing Hip Hemi-arthroplasty
Hip fractures incidence grows rapidly with the aging of the population. After indicated surgical treatment, hip fracture patients experience high rates of postoperative complications, postoperative delirium (PD), postoperative…
- Conditions
- Femoral Neck Fractures, Postoperative Complications, Inflammatory Response, Postoperative Delirium
- Trial name
- NCT01934049
- Testing
- hip arthroplasty, Total Intravenous Anesthesia and Peripheral nerve blocks
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Femoral Neck Fracture
Topical Application of Tranexamic Acid and Postoperative Blood Loss in Femoral Neck Fractures
Tranexamic acid (TA) is a synthetic antifibrinolytic agent. It prevents degradation of fibrin and delays the breakdown of hemostatic clots.
- Trial name
- NCT01727843
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Dr. Jeff Yach
Osteopenic Women, Proximal Femur Fracture
Copley II: Long-term Outcome Follow-up Study of Osteoporotic Women Who Underwent a Local Osteo-Enhancement Procedure (LOEP) in the Proximal Femur
To evaluate longer-term (5-7 years) outcomes of the twelve (12) subjects treated with AGN1 Femoral LOEP in the clinical study "A Prospective Pilot Evaluation of Percutaneous Osteo-supplementation in the Proximal Femur of…
- Trial name
- NCT06799143
- Volunteers
- 12 people
- Sponsor
- AgNovos Healthcare, LLC
Bleeding, Hip Fracture
How Bleeding Affects Delirium in Older Patients With Hip Fractures: The IMPROVE-HIP Study
The goal of this clinical trial is to investigate whether early detection of bleeding and prompt blood transfusions can help prevent delirium in patients aged 75 and older who are admitted to the hospital with hip fractures.
- Conditions
- Bleeding, Hip Fracture, Delirium - Postoperative
- Trial name
- NCT06938789
- Testing
- Blood Transfusion, Standard care
- Where
- 2 sites in Denmark
- Volunteers
- 198 people
- Sponsor
- University of Aarhus
Femoral Neck Fracture
Ropivacaine Hypobaric Spinal Anaesthesia in Traumatic Hip Surgery
This is a prospective, monocentric, randomized study, comparing the effectiveness and tolerance of four different dosages of hypobaric ropivacaine for unilateral spinal anaesthesia during traumatic femoral neck surgery in the…
- Trial name
- NCT01005550
- Testing
- 6 mg of ropivacaine, 8 mg of ropivacaine, 10 mg of ropivacaine
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Hip Fracture, Malnutrition
GNRI and Rectus Femoris Muscle Thickness in Older Patients Undergoing Hip Fracture Surgery
This prospective observational study will evaluate whether nutritional risk and reduced muscle mass are associated with postoperative outcomes in adults aged 65 years or older undergoing surgery for hip fracture.
- Conditions
- Hip Fracture, Malnutrition, Sarcopenia, Postoperative Complications
- Trial name
- NCT07751692
- Testing
- Geriatric Nutritional Risk Index Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Hip Fractures
Cluster-randomized Study of 394 Patients Operated With Direct Anterolateral Approach.
394 participants were cluster-randomized during 2010-2014. Depending on which ward the participants admitted to, they were allotted to free rehabilitation (non-precaution group, NPG, n=226) or our conventional regime with…
- Trial name
- NCT03468192
- Testing
- Non-precaution group
- Volunteers
- 394 people
- Sponsor
- Lund University
Hip Fracture, Testosterone Deficiency
Testosterone Therapy After Hip Fracture in Elderly Women
The purpose of this study is to determine the feasibility of testosterone replacement therapy in frail elderly female hip fracture patients who have testosterone deficiency, and to obtain preliminary information about the effects…
- Conditions
- Hip Fracture, Testosterone Deficiency, Muscle Weakness
- Trial name
- NCT00280267
- Testing
- Testosterone gel
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Washington University School of Medicine
Pertrochanteric Fracture of Femur, Intertrochanteric Fracture of Femur
Retrospective Study Chimaera Long Nail in Adult Patient
The CHIMERA study intends to evaluate the clinical benefits of the study medical device in the standard clinical practice.
- Conditions
- Pertrochanteric Fracture of Femur, Intertrochanteric Fracture of Femur, Subtrochanteric Fracture of Femur
- Trial name
- NCT06285981
- Testing
- Chimaera Long Nail
- Where
- 2 sites in Italy
- Volunteers
- 44 people
- Sponsor
- Orthofix s.r.l.
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