Clinical trials: Femur Fractures
Pelvic Fracture
A Prospective Study of Early Mechanical Stabilization and Bleeding in Disruption of the Pelvic Ring
The objective of this study is to evaluate the effect of earlier placement of Circumferential Pelvic Compression (CPC) on resuscitative measures required for life-threatening pelvic ring injuries and to guide the development of…
- Trial name
- EMS-BIND (NCT03977168)
- Testing
- Application of circumferential pelvic compression (CPC) device
- Where
- 11 sites in United States
- Volunteers
- 600 people
- Sponsor
- Major Extremity Trauma Research Consortium
Hip Fracture
A Proof-of-Concept Study Investigating the Safety and Efficacy of ZT-031 on Hip Fracture Healing in Men and Postmenopausal Women
The purpose of this research study is to test if an experimental drug called ZT-031 can help men over 30 years or post-menopausal women over 55 years of age with certain types of hip fracture to heal better or faster following…
- Trial name
- SHIFT (NCT00787358)
- Testing
- ZT-031
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Zelos Therapeutics
Hip Fractures, Delirium
ED Ultrasonographic Regional Anesthesia to Prevent Incident Delirium in Hip Fracture Patients
Hip fractures are common, costly and affect older people - Canadians spend 1 billion dollars to treat hip fractures each year. Unfortunately, as many as two-thirds of hip fracture cases suffer a complication known as delirium, or…
- Trial name
- EDU-RAPID (NCT02892968)
- Testing
- Fascia-Iliaca Block(FIB), Femoral Nerve Block(FNB)
- Where
- Canada
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Hemorrhage, Pelvic Fracture
Pre-hospital Advanced Therapies for Control of Hemorrhage - Pelvis
The purpose of this study is to determine whether the use of pelvic binders in the ambulance setting improves outcomes including mortality in patients with pelvic fractures.
- Trial name
- PATCH (NCT02855060)
- Testing
- Pelvic Binder
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Intertrochanteric Femur Fracture, Hip Fracture Surgeries
Inflammatory Indices, Early Mortality, and ICU Stay in Geriatric PFN Patients
This retrospective observational cohort study aims to evaluate the association between preoperative and postoperative inflammatory indices and early postoperative outcomes in geriatric patients undergoing proximal femoral nailing…
- Conditions
- Intertrochanteric Femur Fracture, Hip Fracture Surgeries, Geriatric Anesthesia
- Trial name
- PFN-RAR (NCT07607886)
- Where
- Turkey (Türkiye)
- Volunteers
- 233 people
- Sponsor
- Saglik Bilimleri Universitesi
Hip Fractures
Radiologic and Clinical Outcomes of Augmentation in Fragility Intertrochanteric Hip Fracture Treatment
Randomized clinical trial to assess if the use of augmentation in the treatment of fragility intertrochanteric hip fractures improves radiologic and clinical outcomes in patients aged 65 years or older 1 year after surgery
- Trial name
- AFIF (NCT02631824)
- Testing
- open reduction and internal fixation, TFNA, Augmentation (Cement)
- Where
- 2 sites in Colombia
- Volunteers
- 90 people
- Sponsor
- Hospital Infantil Universitario de San Jose
Femoral Fracture, Fragility Fracture
Essential Amino Acid Supplementation for Femoral Fragility Fractures
This trial will evaluate the impact of 4 weeks of postoperative essential amino acid (EAA)-based supplementation on muscle morphology after femoral fragility fracture.
- Conditions
- Femoral Fracture, Fragility Fracture, Muscle Atrophy
- Trial name
- NCT06050668
- Testing
- Essential Amino Acid Supplementation
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Michael C Willey
Hip Fractures
Stroke Volume Optimisation in Patients With Hip Fracture
The aim of this study is to assess whether intra-operative fluid supplementation (to improve tissue perfusion) can reduce the incidence of postoperative complications in elderly patients with hip fracture.
- Trial name
- FRACTALE (NCT00444262)
- Testing
- hemodynamic optimisation guided using esophageal Doppler, VOLUVEN and others solute
- Where
- 19 sites in France
- Volunteers
- 215 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Femur Fractures, Frailty
Predicting of Frailty
This study aims to evaluate the frailty status of elderly patients undergoing surgery for hip fractures (femur trochanteric fractures).
- Conditions
- Femur Fractures, Frailty, Sarcopenia
- Trial name
- PRE-FRAIL (NCT07332052)
- Testing
- Clinical and Functional Assessment, Rectus femoris thickness measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- ali ihsan uysal
Femoral Neck Fractures
Cemented Versus Uncemented Stems in Total Hip Arthroplasty in Patients With Femoral Neck Fractures
The purpose of this prospective randomized study is to compare the quality of treatment between cemented versus uncemented hydroxyapatite coated femoral stems in Total Hip Arthroplasty (THA) in patients who suffers from…
- Trial name
- NCT01578408
- Testing
- Total Hip Arthroplasty, Cemented Lubinus SPII stem (control arm), Uncemented HA Coated Corail stem
- Where
- Sweden
- Volunteers
- 109 people
- Sponsor
- Sahlgrenska University Hospital
Pelvic Fracture
Pelvic Fractures in the Elderly
The aim of the project is to predict the patient under conservative therapy as a function of the patient Classification of Rommens and Hofmann and other potential prognostic factors.
- Trial name
- PelvFx (NCT03476824)
- Where
- Switzerland
- Volunteers
- 400 people
- Sponsor
- University Hospital, Basel, Switzerland
Hip Fracture, Femoral Neck Fracture
Validity and Reliability of Thai Version of Barthel Index for Hip Fracture Patients
Since an increasing in population age, there was an increasing in geriatric patients. Most of elderly patients needed rehabilitation programs to regain their quality of life during their medical treatments.
- Conditions
- Hip Fracture, Femoral Neck Fracture, Intertrochanteric Fracture
- Trial name
- NCT02512094
- Where
- Thailand
- Volunteers
- 53 people
- Sponsor
- Mahidol University
Pseudoarthrosis of Bone, Implant Breakage
Corticalisation After Femoral Nail Dynamization in Hypertrophic Non-unions
In 12 patients with corticalization and hypertrophic pseudarthrosis were present after dynamization, the old nail was removed and nail exchange was performed with a longer and larger diameter nail to pass the region formed in the…
- Trial name
- NCT05423561
- Testing
- exchange nailing with larger, thicker nail crossing corticalization
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Hip Fracture, Femoral Neck Fracture
The Hip Fracture Surgical Approach Trial
The HIFSAT study will compare the standard direct lateral approach to hemiarthroplasty to a new muscle sparing approach (SPAIRE) in femoral neck fracture patients.
- Trial name
- HIFSAT (NCT06146205)
- Testing
- Direct lateral approach, SPAIRE
- Where
- Norway
- Volunteers
- 476 people
- Sponsor
- Diakonhjemmet Hospital
Hip Fracture
Better Hips- Better Function
The focus of this project are elderly people who have experienced hip fracture and need at least two weeks rehabilitation after discharge from hospital.
- Trial name
- NCT02815254
- Testing
- High intensity functional exercise, Low intensity functional exercise
- Where
- Norway
- Volunteers
- 105 people
- Sponsor
- Oslo Metropolitan University
Hip Fracture, Anemia
IV Iron in Association With Tranexamic Acid for Hip Fracture
It is a prospective randomized controlled study aiming to test if tranexamic acid combined to intravenous iron before and after surgery for hip fracture in elderly can decrease peri-operative red cell transfusion.
- Trial name
- NCT02428868
- Testing
- tranexamic acid (Exacyl®), intravenous iron (Ferroven®), Saline
- Where
- Tunisia
- Volunteers
- 150 people
- Sponsor
- Institut Kassab d'Orthopédie
Acute Kidney Injury
PREdicting RENAL Injury In Patient After Hip Fracture Surgery
To determine whether MALDI, a type of Mass-Spectometry, can use protein pattern detection within urine to predict postoperative (after an operation) kidney damage in adults who have undergone emergency hip fracture surgery?
- Trial name
- PRE-RENAL (NCT03049150)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Hip Fractures
Effect of Leg Strengthening Exercise After Hip Fracture
The purpose of this trial was to examine the effectiveness of a short-term leg strengthening exercise program compared to attention control on improving leg strength, walking speed and endurance, physical performance, and…
- Trial name
- NCT00997776
- Testing
- progressive resistance exercise, TENS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Arcadia University
Apoplexy, Femoral Neck Fracture
Epidemiology of Aeromedical Evacuation
Increasing air travel has resulted in a significant increase in aeromedical evacuation over the past decade. However there is only a small amount of epidemiological data available on the diagnosis, costs and transport…
- Conditions
- Apoplexy, Femoral Neck Fracture, Myocardial Infarction, Subarachnoid Hemorrhage
- Trial name
- NCT01071382
- Volunteers
- 504 people
- Sponsor
- Ruhr University of Bochum
Osteoarthritis, Hip, Femur Head Necrosis
Prophylaxis of Deep Vein Thrombosis Following Total Hip Arthroplasty
This prospective study compares an oral direct factor Xa inhibitor with LMWH for thromboprophylaxis in the patients undergoing THA.
- Conditions
- Osteoarthritis, Hip, Femur Head Necrosis, Femoral Neck Fractures
- Trial name
- NCT02379663
- Testing
- Rivaroxaban, Enoxaparin, Normal saline
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center