Clinical trials: Fentanyl
Dysphagia, GERD
Does Use of Topical Lidocaine in EGD Reduce Amount of IV Midazolam and Fentanyl Required and Shorten Recovery Time
Patients will be randomized to a placebo or study group who will receive topical lidocaine prior to EGD. Amount of medication used, recovery time, patient/endoscopist satisfaction will then be assessed.
- Conditions
- Dysphagia, GERD, Abdominal Pain
- Trial name
- NCT02620501
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Brooke Army Medical Center
Gastric Cancer
Comparison of the Analgesic Effect Between Intrathecal Morphine and IV-fentanyl Patient Controlled Analgesia (ITM-IVPCA) and Epidural PCA (PCEA) in Patients Undergoing Gastrectomy -Randomized Allocation Study-
The present study was designed to assess analgesic capacity of intrathecal administration of morphine combined with intravenous fentanyl patient-controlled analgesia (ITM-PCA) compared to patient controlled epidural analgesia…
- Trial name
- NCT01234272
- Testing
- morphine, Ropivacaine
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Yonsei University
Coronary Artery Disease
The Platelet Aggregation After tiCagrelor Inhibition and FentanYl Trial (PACIFY)
With potent analgesic properties, perceived hemodynamic benefits and limited alternatives, opiates are the analgesic mainstay for acute coronary syndrome (ACS) patients reporting peri-procedural pain or nitrate-resistant chest…
- Trial name
- PACIFY (NCT02683707)
- Testing
- Removal of Fentanyl from peri-procedural analgesia, Fentanyl, Lidocaine
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- Johns Hopkins University
Analgesia, Emergencies
Nebulized Fentanyl in Healthy Volunteers
Pain constitutes the predominant motive prompting individuals to seek emergency medical attention, accounting for 80% of admissions to emergency departments.
- Trial name
- AEROfen (NCT06281951)
- Testing
- Fentanyl - Inhalation by facial nebulization, Fentanyl - Nebulisation
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Multiple Trauma, Pain, Acute
Intranasal Ketamine Versus Intranasal Fentanyl
Abstract Background: Given the inadequate control of pain in patients with injury that refer to the emergency departments, the rapid onset of action of intranasal administration in pain management, and the avoidance of…
- Trial name
- NCT04414800
- Testing
- Ketamine, Fentanyl
- Where
- Iran
- Volunteers
- 125 people
- Sponsor
- Isfahan University of Medical Sciences
Pharmacokinetics and Pharmacodynamics
Fentanyl Sublingual Spray and Fentanyl Citrate Intravenous (IV) in Opioid Naive Subjects
The primary objective of this study is to determine the pharmacokinetic and pharmacodynamic relationship of a single dose of fentanyl sublingual spray in opioid naive subjects.
- Trial name
- NCT02576353
- Testing
- Fentanyl, Fentanyl Citrate
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- INSYS Therapeutics Inc
Advanced Cancers, Dyspnea
Breakthrough Dyspnea Fentanyl Study in Cancer Patients
The goal of this clinical research study is to learn if fentanyl given under the skin can reduce shortness of breath in cancer patients. Researchers also want to learn if it can help to improve your physical function.
- Trial name
- NCT01515566
- Testing
- Fentanyl, Walking Tests, Questionnaires
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- M.D. Anderson Cancer Center
Fracture of Proximal End of Femur
Comparison of Analgesic Effectiveness of Intravenous Ketamine and Fentanyl for Spinal Anesthesia is Sitting Position in Patients With Proximal Femur Fracture
This is a prospective comparative study which will be conducted in patients with proximal femur fracture undergoing operative interventions under subarachnoid block in sitting position.
- Trial name
- NCT04418674
- Testing
- Ketamine, Fentanyl
- Where
- 2 sites in Nepal
- Volunteers
- 52 people
- Sponsor
- Jenny Bajracharya
Acute Pain Due to Trauma
Sublingual Versus Endovenous Fentanyl for the Prehospital Analgesia in Patients With Limb Trauma on the Slope
The purpose of this study is to determine the non-inferiority of the efficacy for prehospital analgesia of sublingual administered fentanyl versus endovenous administered fentanyl for patients with limb trauma on the slope
- Trial name
- NCT03080350
- Testing
- Fentanyl sublingual, Fentanyl ev
- Where
- Italy
- Volunteers
- 108 people
- Sponsor
- Azienda Sanitaria dell'Alto Adige
Postoperative Pain
Dexmedetomidine Versus Fentanyl for Sedation of Postoperative Mechanically Ventilated Neonates
Newborn infants experience pain after surgical procedures,prevention and management of pain in neonates is important due to its deleterious consequences.
- Trial name
- NCT05324891
- Testing
- Dexmedetomidine, Fentanyl
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Fentanyl Overdose, Fentanyl Poisoning
A Phase 2 Safety, Tolerability, PK, and Efficacy Study of CS-1103 Following Fentanyl Challenge With Naloxone Blockade
The purpose of the study is to evaluate the safety, tolerability, pharmacokinetics, and efficacy of CS-1103 (1,000 mg), given by intravenous (IV) infusion in healthy participants in the presence of a clinically relevant dose of…
- Trial name
- NCT07459166
- Testing
- Naloxone Hydrochloride, Fentanyl, Sterile Saline
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Clear Scientific, Inc.
Analgesia, Burns
Analgesic Effect of Esketamine in DCSB in Adultscontrolled Study
Patients with severe and above degree burns are often complicated with inhalation injury and systemic infection. During debridement and dressing change in such patients, doctors will be more cautious in using analgesics.
- Trial name
- NCT05603975
- Testing
- Esketamine 0.1mg/kg intravenous injection, Normal saline
- Volunteers
- 52 people
- Sponsor
- Shenzhen Second People's Hospital
Anesthesia
Comparison of 3 Different Density Levobupivacaine Solutions + Fentanyl for Spinal Anaesthesia for Caesarean Delivery.
The investigator's aim is to compare the efficacy of 3 levobupivacaine solutions with different density on spinal anesthesia for caesarean delivery.
- Trial name
- NCT03956303
- Testing
- Chirocaine %0.5, Chirocaine Heavy 40, Chirocaine Heavy 60
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Chronic Pain
Efficacy and Safety Study of Fentanyl Transdermal Patch for Treatment of Chronic Pain
The purpose of this study is to confirm effectiveness and safety of fentanyl transdermal patch Durogesic® D-Trans for treatment of chronic pain in participants with chronic non-cancer pain.
- Trial name
- NCT01902524
- Testing
- Fentanyl-TTS
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Janssen Korea, Ltd., Korea
Pain, Postoperative, Pain Management
Bilateral Serratus Intercostal Plane Block for Myocardial Revascularization (SERRINT)
Two-parallel arm, double-blind, individually randomized controlled trial. Primary endpoint: Fentanyl consumption in the first 48 postoperative hours.
- Conditions
- Pain, Postoperative, Pain Management, Analgesia, Patient-Controlled, Nerve Block
- Trial name
- SERRINT (NCT03813225)
- Testing
- Bilateral serratus Intercostal plane Block
- Where
- Colombia
- Volunteers
- 44 people
- Sponsor
- Fundación Cardiovascular de Colombia
Patients Undergoing Major Abdominal Surgery, Postoperative Confusion
Effect of Remifentanil on Postoperative Cognition Function in Patients Undergoing Major Abdominal Surgery
The purpose of this study is to investigate the effects of two different analgesic methods (Fentanyl vs Remifentanil) during major abdominal surgery on postoperative cognitive status of patients.
- Trial name
- NCT01627873
- Testing
- Remifentanil, Fentanyl
- Where
- Italy
- Volunteers
- 622 people
- Sponsor
- Catholic University of the Sacred Heart
Terminal Cancer
Nasal Fentanyl and Buccal Midazolam for Dying Patients
When patients are dying they become unable to take oral medication and if they develop symptoms (e.g. pain or agitation) they need to be given a subcutaneous injection of medication.
- Trial name
- NCT02009306
- Testing
- PecFent and Epistatus, Standard subcutaneous medication, Epistatus Alone
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Anesthesia
Total Intravenous Anesthesia in Patients Undergoing Craniotomy
Craniotomy presents true anesthetic challenges, mainly due to the need to optimize cerebral perfusion, facilitate brain relaxation, achieve rapid emergence for neurologic assessment, and minimize perioperative complications.
- Trial name
- NCT07105618
- Testing
- Dexmedetomidine, Fentanyl, Magnesium
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Zagazig University
Postoperative Pain
Erector Spinae Plane Block For Postoperative Analgesia in Patients Undergoing Total Abdominal Hysterectomy
The aim of this study was to assess the efficacy of bilateral ESPB on postoperative analgesia in patients undergoing total abdominal hysterectomy under general anesthesia.
- Trial name
- Erector Spinae (NCT03741348)
- Testing
- Erector Spinae Plane Block, control
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Labor Pain
Spinal or Epidural Fentanyl or Sufentanil for Labour Pain in Early Phase of the Labour
In this study the analgesic effect of two different opioids (fentanyl and sufentanil) will be compared when given either intrathecally or epidurally in primiparous parturients during early phase of the labour.
- Trial name
- NCT02885350
- Testing
- Spinal analgesia for labour pain, Epidural analgesia for labour pain
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Helsinki University Central Hospital