Clinical trials: Ferric Carboxymaltose
Postoperative Anemia, Knee Osteoarthritis
Effect of Preoperative Ferric Carboxymaltose After Simultaneous Bilateral Total Knee Arthroplasty
The primary purpose of this study is to evaluate the safety and efficacy of preoperative intravenous ferric carboxymaltose in patients with anemia undergoing Simultaneous Bilateral Total knee replacement in terms of Quality of…
- Conditions
- Postoperative Anemia, Knee Osteoarthritis, Total Knee Arthroplasty
- Trial name
- NCT03561506
- Testing
- Ferric carboxymaltose, 0.9% Normal Saline
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Iron Deficiency
Ferric Carboxymaltose Treatment to Improve Fatigue Symptoms in Iron-deficient Non-anaemic Women of Child Bearing Age
research study of Ferric carboxymaltose to treat fatigue/exhaustion symptoms, believed to be due to iron deficiency.
- Trial name
- Prefer (NCT01110356)
- Testing
- Ferinject, Saline
- Where
- Austria
- Volunteers
- 294 people
- Sponsor
- Vifor Pharma
Anemia
Safety and Tolerability of Ferric Carboxymaltose (FCM) Versus Iron Dextran in Treating Iron Deficiency Anemia
The objective of this study is to evaluate the safety of FCM in patients with anemia who are not dialysis dependent.
- Trial name
- NCT00704028
- Testing
- Ferric Carboxymaltose, Iron Dextran
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- American Regent, Inc.
Metastatic Colorectal Cancer
Intravenous Ferric Carboxymaltose vs. Oral Iron Substitution in Patients With Metastatic Colorectal Cancer (CRC) and Iron Deficiency Anemia: a Randomized Multicenter Treatment Optimization Study.
Iron deficiency has a high prevalence in colorectal cancer patients ranging at ca. 60%. About 70% of these patients suffer from iron deficiency anemia (IDA) which adds both physical and cognitive impediments to an already…
- Trial name
- NCT02469480
- Testing
- FerInject, Ferro sanol
- Where
- 18 sites in Germany
- Volunteers
- 64 people
- Sponsor
- Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
Anaemia
Preoperative Intravenous Iron to Treat Anaemia in Major Surgery
Anaemia is a common problem in patients undergoing surgery. About half of patients undergoing a major operation have anaemia, often a consequence of the disease requiring surgery. Anaemia causes patients to feel tired and unwell.
- Trial name
- PREVENTT (NCT01692418)
- Testing
- Ferric carboxymaltose, Normal saline
- Where
- 28 sites in United Kingdom
- Volunteers
- 487 people
- Sponsor
- University College, London
Iron Deficiency, Anaemia
Safety, Tolerability, PK and PD of Intravenous Ferric Carboxymaltose in Infants With Iron Deficiency Anemia
An Open-Label, Multi-Center Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous Ferric Carboxymaltose (FCM) in Infants (0-1 year) with Iron Deficiency Anemia.
- Trial name
- NCT04968379
- Testing
- Ferric carboxymaltose
- Where
- 4 sites in United States
- Sponsor
- American Regent, Inc.
Iron-deficiency
Ferric Carboxymaltose to Improve Skeletal Muscle Metabolism in Heart Failure Patients With Functional Iron Deficiency
The purpose of this study is to better understand how body levels of iron affect the ability to exercise in patients with heart failure (HF).
- Trial name
- NCT03218384
- Testing
- Ferric Carboxymaltose, 31P MRS/MRI
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
ICU Anemia, Functional Iron Deficiency
Randomized Study Comparing Ferric Carboxymaltose to Iron Sucrose to Treat Fe Deficiency in the Surgically Critically Ill
Critically ill surgical patients are observed to have a functional iron deficiency which contributes to anemia, iron-deficient erythropoiesis, and an increased red blood cell transfusion requirement.
- Trial name
- NCT02009943
- Testing
- Ferric carboxymaltose, Iron sucrose
- Where
- United States
- Sponsor
- Denver Health and Hospital Authority
Anemia, Orthopedic Surgery
Intravenous Ferric Carboxymaltose (Ferinject) in Patients Undergoing Orthopaedic Surgery
The primary purpose of this study is to evaluate the safety and efficacy of preoperative intravenous ferric carboxymaltose in patients with anemia undergoing hip or knee replacement
- Conditions
- Anemia, Orthopedic Surgery, High Risk of Blood Loss
- Trial name
- PRIVIRON (NCT01345968)
- Testing
- Ferinject 50 mg/ml, NaCl 0.9%
- Where
- 2 sites in Germany
- Volunteers
- 3 people
- Sponsor
- University Hospital Muenster
Anemia, Anemia, Postpartum
Comparative Analysis of Oral Iron With Injectable Ferric Carboxymaltose for Post Partum Iron Deficiency Anaemia
The aim of this open label, interventional, randomized controlled clinical trial is to compare the efficacy and safety of ferric carboxymaltose injection with oral iron in treatment of postpartum iron deficiency anaemia in…
- Conditions
- Anemia, Anemia, Postpartum, Iron Deficiency Anemia of Pregnancy, Iron Deficiency Anemia Treatment
- Trial name
- NCT07648628
- Testing
- Ferric Carboxymaltose (FCM)
- Where
- India
- Volunteers
- 200 people
- Sponsor
- ESI-PGIMSR, Basaidarapur
Cardiac Surgery, Transfusion
Transfusion Savings in Heart Surgery: Impact of Individual Strategy by Erythropoietin and Metabolic Adjustment (ScvO2)
Preoperative anemia, bleeding and transfusions have been recognized as a "Deadly triad" in cardiac surgery associated with an increased morbidity,mortality, and costs related.
- Conditions
- Cardiac Surgery, Transfusion, Perioperative Anemia
- Trial name
- BLOOCOST (NCT04141631)
- Testing
- EPO (600UI/Kg, sub-cutaneous) and Ferric Carboxymaltose (FCM) (20 mg/kg in 250 mL of saline solution 0.9% over 15 min)
- Where
- France
- Volunteers
- 128 people
- Sponsor
- University Hospital, Montpellier
Inflammatory Bowel Disease, Anemia
FERINJECT for Correction of Anaemia in IBD Patients, FER-IBD-COR
The purpose of this study is to determine how safe, tolerable and effective the new standardised dosage regimen of FERINJECT® infusions is, compared with a well established intravenous iron treatment.
- Conditions
- Inflammatory Bowel Disease, Anemia, Iron Deficiency, Iron-Deficiency Anemia
- Trial name
- FER-IBD-COR (NCT00810030)
- Testing
- Ferric carboxymaltose, Iron Sucrose
- Where
- Austria
- Volunteers
- 484 people
- Sponsor
- Vifor Pharma
Iron Deficiency Anaemia, Iron Deficiency Anemia
Incidence of Hypophosphatemia After Treatment With Iron Isomaltoside/Ferric Derisomaltose vs Ferric Carboxymaltose in Subjects With Iron Deficiency Anaemia
The trial was designed to evaluate the incidence of unintended hypophosphatemia (low level of phosphate in the blood) in subjects with iron deficiency anaemia (IDA).
- Trial name
- NCT03238911
- Testing
- Iron isomaltoside/ferric derisomaltose, Ferric carboxymaltose
- Where
- 16 sites in United States
- Volunteers
- 123 people
- Sponsor
- Pharmacosmos A/S
Iron Deficiency Anemia in Pregnancy
Comparing Two Intravenous Iron Treatments for Anemia in Kurdish Pregnant Women
The goal of this clinical trial is to compare two types of intravenous (IV) iron-Ferric Carboxymaltose (FCM) and Iron Sucrose (IS)-to learn which one works better to treat iron deficiency anemia in pregnant women who have a clear…
- Trial name
- NCT07721519
- Testing
- Intravenous Ferric Carboxymaltose (FCM), Iron Sucrose (IS) Infusion
- Volunteers
- 400 people
- Sponsor
- Hawler Medical University
Iron Deficiency Anemia
A Phase III Safety Study of Ferumoxytol Compared to Ferric Carboxymaltose for the Treatment of Iron Deficiency Anemia (IDA)
To evaluate the safety of 1.020 grams (g) of intravenous (IV) ferumoxytol compared to 1.500 g of IV ferric carboxymaltose (FCM).
- Trial name
- NCT02694978
- Testing
- Ferumoxytol, FCM
- Where
- 127 sites in United States, Canada and 5 more
- Volunteers
- 2,014 people
- Sponsor
- AMAG Pharmaceuticals, Inc.
Iron Deficiency Anemia
Polyglucoferron Compared to i.v. Ferric Carboxymaltose and Oral Iron Substitution in Preoperative Treatment of Iron Deficiency Anaemia in Patients
Patients with IDA and for whom fast replenishment of iron stores is necessary, e.g. if its not appropriated to postpone surgery, will be identified within 28 to 42 days before surgery.
- Trial name
- IDA-I (NCT04087993)
- Testing
- Polyglucoferron, Ferric carboxymaltose, Ferrous Sulfate
- Where
- Germany
- Sponsor
- Dr. Frank Behrens
Heart Failure, Anemia
Pilot Study of Ferric Carboxymaltose to Treat Iron Deficiency in Asians With Heart Failure
Heart failure (HF) is a major global public health issue which also affects Asia. Data from the National Registry of Disease in Singapore shows a 9.4% rise in HF admissions in public hospitals from 2008 to 2009 (4140 to 4530).
- Conditions
- Heart Failure, Anemia, Iron Deficiency
- Trial name
- PRACTICEASIAHF (NCT01922479)
- Testing
- Ferric Carboxymaltose
- Where
- 2 sites in Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Coronary Artery Disease
Effect of Intravenous Ferric Carboxymaltose on Hemoglobin Response and Transfusion in Patients With Iron Deficiency Anemia After Off-Pump Coronary Artery Bypass Grafting
In this prospective open-label randomized tral, 100 patients with elective off-pump coronary artery bypass (OPCAB) or minimal invasive direct coronary bypass (MIDCAB) surgery were enrolled.
- Trial name
- NCT04898569
- Testing
- Ferinject, Normal Saline Flush
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Pulmonary Disease, Chronic Obstructive
Effect of Intravenous Iron (Ferinject®) on Exercise Capacity and Quality of Life of Stable COPD Patients
Disordered iron metabolism characterizes an important determinant of impaired exercise tolerance and work capacity. Iron-deficiency anemia commonly features impaired aerobic capacity caused by decreased oxygen carrying capacity…
- Trial name
- NCT02416778
- Testing
- Ferric carboxymaltose, Ferinject® 50mg Iron/ml Solution for Injection / Infusion
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Georg-Christian Funk
Iron Deficiency Anemia Associated With Non-Dialysis Dependent Chronic Kidney Disease
Efficacy of Ferric Carboxymaltose Versus Iron Sucrose in Non-dialysis Dependent Chronic Kidney Disease Patients
The goal of this clinical trial is to learn if Ferric Carboxymaltose is a safe efficacious alternative to Iron Sucrose for treatment of Iron deficiency anemia in non-dialysis dependent chronic kidney disease patients.
- Trial name
- NCT06994065
- Testing
- Ferric Carboxymaltose (FCM), Iron Sucrose injection
- Where
- Pakistan
- Volunteers
- 128 people
- Sponsor
- Sindh Institute of Urology and Transplantation