Clinical trials: Fertility
Fertility Disorders
Timing Frozen Embryo Transfer by Following Two Different Methods
This proof of concept study is designed to determine the practicality of using home ovulation tests to enable optimum timing for transfer of frozen embryos in a natural menstrual cycle in comparison to the standard ultrasound and…
- Trial name
- NCT03156374
- Testing
- Test use
- Where
- Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Healthy Japanese Young and Elderly Male and Non-fertile Female Volunteers
A Two-part Single and Multiple Dose Study to Assess the Safety , Pharmacokinetics and Effects of AZD3293 in Healthy Japanese Young and Elderly Volunteers
This study consists of two parts, ie, single dose part with young healthy subjects (Part 1) and single and multiple dose part with elderly healthy subjects (Part 2), to assess the safety, tolerability, pharmacokinetics and…
- Trial name
- NCT02005211
- Testing
- AZD3293
- Where
- Japan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Fertility Disorders
Data Collection and Professional Simulated Use Study to Develop an Embryo Quality Artificial Intelligence (AI) Model
This protocol supports the reliable development and improvement of Artificial Intelligence (AI)-based applications by enabling training, verification, and validation using high-quality real clinical data.
- Trial name
- NCT07017972
- Testing
- AI evaluation of embryos
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Fairtility
Trying to Conceive
Integration of the Oura Ring and Maven Clinic Among Women Who Are Trying to Conceive
This study aims to characterize Oura Ring users who are trying to conceive. It also evaluates the feasibility and clinical outcomes of integrating Oura data with Maven's clinical support platform.
- Trial name
- NCT07862829
- Where
- United States
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- Ouraring Inc.
Healthy
Study to Assess Safety, Tolerability and Pharmacokinetics After Single Doses of AZD1446 to Healthy Volunteers
The primary purpose of this study is to assess the safety and tolerability of AZD1446 following single dose administration.
- Trial name
- SAD (NCT00803855)
- Testing
- AZD1446
- Where
- Sweden
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Fertility Risk
Anti-Mullerian Hormone - At My Home
The AMH^2 (Anti-Mullerian Hormone - At My Home) study is a head-to-head-to-head validation study aiming to evaluate the concordance of AMH levels found in blood collected via three different routes: collected at-home using the…
- Trial name
- AMH^2 (NCT04784325)
- Testing
- Blood draw through TAP II, Blood draw through ADx cardT, Blood draw through standard venipuncture
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Turtle Health, Inc.
Healthy Volunteers
AZD6088 Single Ascending Dose Study
The aims of the study are to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of AZD6088 following single ascending dose administration in healthy male and non-fertile females.
- Trial name
- NCT00931541
- Testing
- AZD6088
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Pregnancy
Clearblue Advanced Fertility Monitor Consumer Three Cycle at Home Study
This study will assess the use of the new Clearblue Advanced Fertility Monitor in a home setting for three menstrual cycles or until pregnancy is achieved (whichever comes first) by female volunteers seeking to get pregnant.
- Trial name
- NCT02535260
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Amenorrhea, Fertility
A Study to Measure Pharmacokinetic (PK) Concentrations of Gonadotropin-Releasing Hormone Delivered by the OmniPod Pump
One of the Causes of Amenorrhea is hypothalamic amenorrhea, which is a deficiency in the amplitude and/or frequency of endogenous Gonadotropin-releasing hormone (GnRH) Pulses.
- Conditions
- Amenorrhea, Fertility, Infertility
- Trial name
- NCT07152730
- Testing
- Lutrepulse
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Contraception
Transdermal Contraceptive Patch - Endometrial Effects Study
The aim of the present study is to investigate the effects of the transdermal patch on the endometrium in healthy women who require contraception.
- Trial name
- NCT00896571
- Testing
- Ethinylestradiol/Gestogene (BAY86-5016)
- Where
- Germany
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Bayer
Fertility
An Ethno-bridging Study of Pergoveris in Healthy Premenopausal Participants of Japanese or Caucasian Origin
The purpose of this study is to assess the Pharmacokinetic (PK) of Recombinant human follicle-stimulating hormone (follitropin alfa) (r-hFSH) and Recombinant human luteinizing hormone (lutropin alfa) (r-hLH) following a single…
- Trial name
- NCT07269327
- Testing
- Desogestrel and ethinylestradiol fixed dose combination, Follitropin alfa/lutropin alfa
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany
Contraception, Bleeding Pattern
Assessment of a Vaginal Ring With Meloxicam on Ovarian Cycle in Fertile Women
In this study, the investigators propose to assess if a non-hormonal agent is absorbed by a local route (vaginal) and to observe the effect on follicular development.
- Trial name
- NCT01839643
- Testing
- Meloxicam 2.4 g, Meloxicam 3.0 g
- Where
- Chile
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Laboratorios Andromaco S.A.
Healthy Volunteers
Assess Safety, Tolerability and Pharmacokinetic (PK) of AZD1704 in Healthy Japanese Male and Non-Fertile Female Volunteers
The primary objective of this study is to investigate the safety and tolerability of AZD1704 following single ascending doses in healthy Japanese male and non-fertile female volunteers by assessment of adverse events (AEs), vital…
- Trial name
- NCT00736788
- Testing
- AZD1704
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Infertility, Vaginal Flora Imbalance
Evaluate the Use of a New Probiotic Strain in Couples With Fertility Problems and Dysbiosis.
Pilot study to evaluate the effect of the strain Lactobacillus PS11610 on the microbiota of the female and male genital tract in couples with fertility problems.
- Conditions
- Infertility, Vaginal Flora Imbalance, Genital Disorder
- Trial name
- PROFEC (NCT03701893)
- Testing
- Lactobacillus PS11610
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Pregnancy, Fertility
Home Ovulation Test One Cycle at Home Study
This study will assess the usability of a Home Ovulation Test when used at home by lay-users seeking to conceive.
- Trial name
- NCT04667858
- Testing
- Home Ovulation Test
- Where
- United Kingdom
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Part A Healthy Young Males and Non-fertile Female Volunteers Aged 20 to 45 Years., Part B Healthy Young Males and Non-fertile Female Volunteers Aged 20 to 45 and Elderly Volunteers Aged 60 to 80
To Investigate the Safety, Tolerability and Pharmacokinetics of AZD2516 After Multiple Dosing in Healthy Volunteers
AZD2516 is being developed for the oral treatment of chronic neuropathic pain. This study is split in to two parts. Part A will measure the effect of food and a new formulation of the drug in the blood and see how well it is…
- Trial name
- NCT01148095
- Testing
- AZD2516
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Tolerability
Study to Investigate Single Ascending Oral Doses of AZD5213 in Healthy Male and Non Fertile Female Subjects
1. The main purpose of this study is to assess the safety and tolerability of AZD5213 after single oral doses. 2. Another purpose of this study is to evaluate the pharmacokinetics (also called PK - how the study drug enters and…
- Trial name
- NCT01121302
- Testing
- AZD5213
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Sperm Parameters in Fertile and Infertile Men
Evaluation of New Semen Collection & Transportation Kit
Examine the effect of overnight transport conditions on sperm parameters on semen samples collected and mailed to Cleveland Clinic Andrology center.
- Trial name
- NCT04536545
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Turtle Health, Inc.
Fertility
Fertility in Healthy Premenopausal Women
The study objectives are described below: 1. Obtain serum specimens collected for one ovulatory cycle or a maximum of 33 days, but not to exceed a total of 550 ml of whole blood per subject from a minimum of 60 healthy…
- Trial name
- NCT02772848
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fujirebio Diagnostics, Inc.
Healthy
Assessment of Relative Bioavailability of NKTR-118 in Three Formulations in Healthy Subjects
The is an assessment of Relative Bioavailability of NKTR-118 in Three Formulations in Healthy Subjects.
- Trial name
- NCT01365000
- Testing
- NKTR118 Formulation 1, NKTR118 Formulation 2, NKTR118 Formulation 3
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- AstraZeneca