Clinical trials: Fertility
Infertility
The Impact of Personalized Prognostic Counseling on IVF Patient's Experience and Treatment Utilization
This study will be conducted in two phases. In the first phase, research subjects will be assigned to receive standard counseling. In the second phase, research subjects will receive Univfy counseling.
- Trial name
- NCT06319573
- Testing
- Counseling Supported by Univfy® Report, Standard Counseling
- Where
- 2 sites in Spain
- Volunteers
- 366 people
- Sponsor
- Ginefiv
Childhood Cancer, Fertility Disorders
Female Fertility Preservation Using Ovarian Tissue Cryopreservation Before Highly Gonadotoxic Cancer Treatment
Background: Due to the remarkable improvement in treatments these last decades, long term survival can be expected in more than 80% of childhood cancer patients.
- Trial name
- NCT03180827
- Testing
- ovarian tissue biopsy
- Where
- 2 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- Gumy-Pause Fabienne
Cancer, Cancer-Related Condition
Testicular Tissue Cryopreservation in Children
This protocol is being designed to offer testicular tissue cryopreservation to male pediatric patients (0-17 years of age) with fertility threatening medical diagnoses or facing surgery, chemotherapy or radiation therapy that may…
- Conditions
- Cancer, Cancer-Related Condition, Infertility
- Trial name
- NCT02872532
- Testing
- Testicular tissue cryopreservation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Fertility Sparing
Medroxyprogesterone Acetate vs LNG-IUS in Early-stage Endometrioid Carcinoma and Atypical Hyperplasia Patients
In modern society, endometrial cancer (EC) and atypical hyperplasia is the most frequent desease which can affect the fertility of young patients. For young patients, there is a growing need to treat tumors and fertility sparing.
- Trial name
- NCT05565573
- Testing
- Medroxyprogesterone Acetate 500 MG Oral Tablet, Levonorgestrel-Releasing Intrauterine System
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Hua Li
Healthy
Contraception in Normal and Subnormal Men
Volunteers with normal and subnormal semen parameters receive a hormonal male contraceptive in order to investigate whether there are differences between normal and subnormal men in terms of suppressibility, rate of azoospermia…
- Trial name
- NCT00167141
- Testing
- injection of hormonal male contraceptive
- Where
- Germany
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
INFERTILITY, Fertility Preservation
Evolutive Potential of Embryos Obtained From Oocytes After Luteal Phase Ovarian Stimulation
The purpose of this study is to evaluate the clinical pregnancy rate per embryo transfer in oocytes recipients obtained after ovarian stimulation during the luteal phase of oocytes donors .
- Conditions
- INFERTILITY, Fertility Preservation, Ovulation Induction, Vitrification
- Trial name
- NCT01645241
- Testing
- gonadotropins plus GnRH antagonists, ganirelix
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Fundacion Dexeus
Breast Cancer
Oocyte Recovery During Tamoxifen Adjuvant Therapy
Survival in young patients with cancer has increased and also have increased the adverse long-term side effects of chemotherapy, there is a large number of women who experience loss of ovarian function without accomplishing their…
- Trial name
- TAMOXIFERT (NCT02355600)
- Testing
- Oocyte retrieval
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Gonadal Dysfunction, Gonadal Failure
Fertility Enhancement Through Regenerative Treatment in Ovaries and Testes
This study investigates the safety and efficacy of stem cell or stem cell-derived exosome therapy for gonadal failure, including testicular failure, hypogonadism, ovarian insufficiency, and premature ovarian failure (POF).
- Conditions
- Gonadal Dysfunction, Gonadal Failure, Azoospermia, Testosterone Deficiency
- Trial name
- FERTILE (NCT06841328)
- Testing
- Stem cells
- Where
- United Arab Emirates
- Volunteers
- 60 people
- Sponsor
- Jumeirah American Clinic
Infertility, Female
The Potential Effects of Inofolic Plus on Abnormal Ovarian Reserve Parameters in Subfertile Women
Dr. Roseff and his colleagues are conducting a study to evaluate the effectiveness of a novel substance (Inofolic Plus®) in improving oocyte (egg) parameters in subfertile female patients, as measured through Anti-Mullerian…
- Trial name
- NCT01290432
- Testing
- Inofolic Plus
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Palm Beach Center for Reproductive Medicine
Fertility Issues
Follicular FSH Serum Level as a Predictor of an Oocyte Yield and Quality in Fertility Preservation Cycles for Women With a Compromised Ovarian Reserve
The incorporation of ovarian reserve tests in IVF management started after initial publications indicating a potential role for basal FSH in predicting pregnancy outcome after IVF and in counseling patients (1,2).
- Trial name
- NCT05536999
- Testing
- Blood sample taking , like to measure hormonal level like LH, FSH, Perlakan ,in a follicular fluid after the oocyte retrival
- Where
- Israel
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Genetic Disorder, Fertility Disorders
Retrospective Study on Clinical Results of Preimplantation Genetic Screening at Different Embryo Stage
Preimplantational genetic screen (PGS) is tool for diagnosis of embryo chromosome abnormality before transfer. Under this tool, patients with a family history of genetic disease or special genetic disease could avoid to produce…
- Conditions
- Genetic Disorder, Fertility Disorders, Reproductive Disorder
- Trial name
- NCT03065114
- Testing
- PGS
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yeh
Willingness-to-pay, Patient-centredness
Willingness to Pay for Patient-centred Care
The purpose of this study is to evaluate the monetary value of patient-centrednes in health care by determining a willingness-to-pay for more patient-centredness care for both patients and health insurers
- Trial name
- NCT01834313
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- A.G. Huppelschoten
Endometriosis, Infertility
Infertility and Endometriosis Cohort
Nowadays, one in six couples consults for fertility problems. If the standard examination and tests do not reveal any cause of infertility, the woman may undergo a laparoscopic exploration which reveals endometriosis in more than…
- Trial name
- EndoFertil (NCT01833013)
- Testing
- live birth date and quality of life assessment
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Male Subfertility, Oligospermia
7 NUTS Study. Diet Modification and Male Fertility.
Setting. Outpatient fertility clinic. Aim. Investigate if a modification in nutritional habits may improve in the short term the qualities of human sperm, testing two hypothesis: i) that adding to the diet a natural whole food…
- Conditions
- Male Subfertility, Oligospermia, Asthenospermia, Teratospermia
- Trial name
- NCT02063256
- Testing
- 7 nuts a day, Diet modification
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Male Infertility, Male Hypogonadism
Relationship of the Microenvironment and Male Fertility
Although much is known about the microenvironment of the gut and the vagina, very little has been published on the microenvironment of the seminal plasma.
- Trial name
- NCT04704141
- Testing
- Hormone replacement therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Illinois at Chicago
Infertility, Female
Ovarian Tissue Cryopreservation
Ovarian Tissue Freezing For Fertility Preservation In Girls Facing A Fertility Threatening Medical Diagnosis Or Treatment Regimen
- Trial name
- OTC (NCT06710769)
- Testing
- Ovarian tissue removal will be performed laparoscopically
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Phoenix Children's Hospital
Infertility
Follicle Activation by Inhibition of the Hippo Pathway
The aim of this project is to activate recruitment and growth of resting primordial follicles in the ovaries of women with diminished ovarian reserve, in attempt to increase the chance to become pregnant, either naturally or…
- Trial name
- NCT02792569
- Testing
- Biopsy of ovarian cortical tissue
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Anders Nyboe Andersen
Young Womenwith Breast Cancer
Multidisciplinary Shared Decision Making of Fertility Preservation in Young Women With Breast Cancer
Multidisciplinary shared decision making of fertility preservation in Young womenwith Breast Cancer (MYBC): A Pragmatic stepped wedge cluster randomised trial
- Trial name
- MYBC (NCT05139641)
- Testing
- Counseling to preserve fertility
- Where
- South Korea
- Volunteers
- 4,100 people
- Sponsor
- MedicalExcellence
Fertility Agents, Female
hCG Supplementation in Frozen-Thawed Embryo Transfer Cycle
The implantation rate after frozen-thawed embryo transfer cycles depends mostly on the receptivity of the endometrium and the embryo quality.The effects of human chorionic gonadotropins (hCG) on the endometrium have been…
- Trial name
- NCT00398229
- Testing
- s.c. human chorionic gonadotropin (Ovitrelle)
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
Varicocele, Pain
"Outcome of Varicocelectomy on Normal Semen in Patients Complaining of Orchialgia
varicoclelectomy is done for subfertiltiy and varicocele induced orchialgia. The effect of varicocelectomy on semen analysis is controversial. Many articles report favorable outcomes and others do not.
- Conditions
- Varicocele, Pain, Fertility Issues
- Trial name
- NCT04509869
- Testing
- varicocelectomy
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University