Clinical trials: Fertility
Endometriosis
Laparoscopic Surgical Management of Endometriosis on Fertility
The aim of the investigators study is to know the results of the endometriosis surgery and particularly to highlight a benefit of this surgery on fertility.
- Trial name
- NCT02481739
- Testing
- retrospective study
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Fertility
Creation of a Biobank of Fertile Men
Collection and conservation of human biological material from fertile subjects, i.e. men with previous parenthood (normospermic men, natural fathers).
- Trial name
- NCT06189677
- Testing
- Observation of biological characteristics of fertile men
- Where
- 2 sites in Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS San Raffaele
Endometrial Cancer, Endometrial Intraepithelial Neoplasia
A Multi-center Prospective Study on the Oncological and Reproductive Outcomes and Quality of Life in Young Woman After Fertility-sparing Treatment of Endometrial Cancer and Endometrial Intraepithelial Hyperplasia
We will investigate the safety and efficiency of fertility-sapring treatment in ypung women witg endometrial cancer and endometrial intraepithelial hyperplasia
- Conditions
- Endometrial Cancer, Endometrial Intraepithelial Neoplasia, Fertility-sparing Surgery
- Trial name
- PreFerEC/EIN (NCT06745427)
- Volunteers
- 100 people
- Sponsor
- Region Stockholm
Breast Cancer
The Young Women's Breast Cancer Study
The investigators are conducting a longitudinal cohort study of young women with breast cancer. The investigators identify women age 40 and younger with newly-diagnosed breast cancer from academic and community healthcare…
- Trial name
- HOHO (NCT01468246)
- Where
- 13 sites in United States, Canada
- Volunteers
- 1,302 people
- Sponsor
- Dana-Farber Cancer Institute
Fertility Issues, Breast Cancer
Effects of Naturalistic Decision-Making Model-based Oncofertility Care Education
his study examined the effects of an oncofertility education program on decisional conflict in nurses caring for breast cancer patients and patients with breast cancer. Other predictors of decisional conflict were also examined.
- Conditions
- Fertility Issues, Breast Cancer, Education
- Trial name
- NCT04600869
- Testing
- Naturalistic Decision-Making Model-based Oncofertility Care Education
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Mackay Medical College
Fertility Issues
The Combination of Sperm Selection by IMSI and Hyaluronic Acid Binding Assay May Improve ICSI Outcome.
In this prospective randomized sibling-oocytes blinded study, investigators examine the combination of two sperm selection methods that logically seem to complete each other, and potentially may improve ICSI outcomes.
- Trial name
- NCT06156722
- Testing
- Sperm selection by IMSI, Sperm selection by IMSI and spermslow
- Where
- Israel
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Cancer
The Impact of CAR-T Cell Therapy on Fertility; A Patient Survey
As there is limited knowledge regarding the impact of CAR-T Cell therapy on fertility, LLS has designed a Patient Survey to learn more about the impact on fertility in patients who have received/are receiving CAR-T Cell…
- Trial name
- NCT07173322
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Blood Cancer United
Ovarian Cancer
Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation
The "Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation" study is open to a subset of patients with disorders of sex development (DSD) which is associated with the risk of malignancy and a high risk of…
- Trial name
- NCT06518746
- Testing
- Cryopreservation of gonadal tissue
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Hypertension, Pulmonary
The Effect of Tracleer® on Male Fertility
The objective of the study is to evaluate the effects of chronic TRACLEER® treatment on testicular function via semen analysis in male patients with primary pulmonary arterial hypertension (PAH).
- Trial name
- NCT00082186
- Testing
- bosentan
- Volunteers
- 22 people
- Sponsor
- Actelion
Fertility Disorders
The Circadian Variability of Serum Progesterone During the Day of a Frozen Embryo Transfer
Serum progesterone levels will be evaluated at four different time points during the day of an artificially prepared frozen embryo transfer cycle (HRT FET cycle) and a modified natural cycle frozen embryo transfer cycle (mNC FET…
- Trial name
- CIRCAPRO (NCT05511272)
- Testing
- blood test
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- Universitair Ziekenhuis Brussel
Morbid Obesity
Bariatric Surgery Outcomes
The UCLA Metabolic and Bariatric Surgery Program (adult program) and the UCLA Fit for Healthy Weight Program (adolescent program) are committed to the care of morbidly obese patients. This study is observational.
- Trial name
- NCT01057784
- Testing
- Bariatric surgery.
- Where
- 2 sites in United States
- Sponsor
- University of California, Los Angeles
Reproductive Performance Following Ovarian Transplantation
Transplantation of Frozen Thawed Ovarian Tissue High Reproductive Performance
Design: prospective cohort study. Setting: Tertiary university-affiliated ART and oncology centers. Patients: 20 cancer survivors who underwent ovarian transplantation of frozen-thawed ovarian tissue, with the aim to conceive.
- Trial name
- NCT02659592
- Testing
- transplantation of ovarian tissue
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Endometrium Cancer, Physical Activity
Effect of Physical Activity Intervention on Overweight and Obese Patients With Endometrial Cancer
This study evaluated the clinical outcome of exercise management on patients with endometrial cancer treated with fertility preservation, including the effect of complete response rate, complete response time, recurrence rate…
- Conditions
- Endometrium Cancer, Physical Activity, Weight Management
- Trial name
- NCT06312917
- Testing
- Physical activity
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Peking University People's Hospital
Sub Fertility, Female, Fertility Disorders
Effects of Fasting on Success Rates of Assisted Reproductive Techologies
This exploratory study investigates fasting as a potential supportive therapy for infertility treatment in women undergoing in-vitro-fertilization (IVF) / intracystoplamsatic sperm injection (ICSI)
- Conditions
- Sub Fertility, Female, Fertility Disorders, Fertility Issues, Sub-fertility
- Trial name
- KiWuC (NCT04998591)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Charite University, Berlin, Germany
Obesity, Overweight
Mazdutide Plus LNG-IUS for Fertility-Sparing Treatment of AEH or Early Endometrial Cancer
This is a prospective, multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial designed to evaluate the efficacy and safety of mazdutide combined with a levonorgestrel-releasing intrauterine…
- Conditions
- Obesity, Overweight, Atypical Endometrial Hyperplasia, Endometrial Carcinoma Stage I
- Trial name
- MELIA (NCT07781150)
- Testing
- Mazdutide(Dual GLP-1R/GCGR Agonist), Levonorgestrel-releasing intrauterine system
- Where
- 6 sites in China
- Volunteers
- 128 people
- Sponsor
- Tongji Hospital
Infertility
Diafert for Embryo Selection and Fertility Improvement (DESTINy)
Prospective, single-center, single-blind, randomized, controlled, two-arm, interventional study.
- Trial name
- DESTINy (NCT02593513)
- Testing
- Daifert, Control Group
- Where
- Hungary
- Volunteers
- 108 people
- Sponsor
- Forest Laboratories
Endometriosis
Role of Medical Treatment in Endometriosis Patients Undergoing ICSI
The aim of this study to assess the effect of medical treatment prior to stimulation on fertility (ICSI) outcome in cases with endometriosis associated infertility.
- Trial name
- NCT06577974
- Testing
- Combined contraceptive pills (Yasmin)
- Where
- 2 sites in Egypt
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fertility Disorders
Comparison Between Testosterone and Estradiol Over the Homogenization of Follicular Cohort
In vitro fertilization(IVF) with Gonadotropin-releasing hormone (GnRH) antagonist is one of the most used protocol for the treatment of infertile couples nowadays.
- Trial name
- NCT03238092
- Testing
- Testosterone, Estradiol
- Volunteers
- 26 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cancer, Fertility Preservation
Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients
The purpose of this study is to evaluate the effectiveness of a multi-component intervention to improve young cancer survivors' engagement in goal-concordant oncofertility care, concurrently with observing and gathering…
- Trial name
- NCT05443737
- Testing
- Multi-component oncofertility care intervention
- Where
- 4 sites in United States
- Volunteers
- 2,800 people
- Sponsor
- University of California, San Diego
CAH - 21-Hydroxylase Deficiency
Parenting and CAH - 21-hydroxylase Deficiency
Congenital adrenal hyperplasia (CAH) is a genetic disease with autosomal recessive transmission, which is defined by a deficiency of one of the steroidogenesis enzymes.
- Trial name
- PARENT-HCS (NCT06900153)
- Testing
- phone questionnaire
- Where
- 7 sites in France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris