Clinical trials: Fertility Disorders
Breast Neoplasm Female, Fertility Preservation
Web-based Oncofertility Support Tool for Reproductive-age Women With Breast Cancer
The aim of this study was to develop electronic systems (e-systems) for oncofertility support, and to examine the comprehensibility, feasibility, usability, and effects on social support and preparation for decision-making.
- Trial name
- NCT05100498
- Testing
- Web-based oncofertility support tool
- Where
- Taiwan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mackay Medical College
Acute Leukemia
Gynecological Impact of Allogeneic Hematopoietic Stem Cell Transplantation in Adults
Gynecological impact and infertility are major issues for women after allogeneic hematopoietic stem cell transplantation. The aim of the present study is to investigate the prevalence of gynecological complications after…
- Trial name
- GYNEGRAFT (NCT07048730)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Bordeaux
IVF Outcomes
HELIOS: Human Embryo Illumination to Enhance Development
Embryos need a lot of energy to grow, but as women get older, the "power plants" of the cells (called mitochondria) don't work as well. This makes it harder for embryos to develop normally.
- Trial name
- HELIOS (NCT07311928)
- Testing
- Photobiomodulation
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Columbia University
Infertility
Diafert for Embryo Selection and Fertility Improvement
Prospective, single-center, single-blind, randomized, controlled, two-arm, interventional study.
- Trial name
- DESTINy (NCT02586272)
- Testing
- Daifert, Control Group
- Where
- Belgium
- Volunteers
- 61 people
- Sponsor
- Forest Laboratories
Infertility, Female
Preservation of Women's Fertility: Evaluation of Innovative Methods for Ovarian Tissue Cryopreservation
The recent innovations in cancer diagnosis and therapy have improved the five-year survival for patients. However, anticancer treatments may impair patient fertility; therefore fertility preservation is recommended before therapy…
- Trial name
- FERTIOVO (NCT06724471)
- Testing
- Human ovarian tissue cryopreservation using thermosoldered or screwed cryovials
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Clermont-Ferrand
Breast Cancer, Lymphoma
Longitudinal Sexual and Reproductive Health Study of Women With Breast Cancer and Lymphoma
The purpose of this study is to see how cancer treatment affects sexual and reproductive function. The patient will also be asked to participate in blood draws to see if and how cancer treatment affects the ovaries and the…
- Conditions
- Breast Cancer, Lymphoma, Hodgkin's Lymphoma
- Trial name
- NCT01788839
- Testing
- surveys, Blood draw, Transvaginal ultrasounds
- Where
- 7 sites in United States
- Volunteers
- 475 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Endometriosis
Laparoscopic Surgical Management of Endometriosis on Fertility
The aim of the investigators study is to know the results of the endometriosis surgery and particularly to highlight a benefit of this surgery on fertility.
- Trial name
- NCT02481739
- Testing
- retrospective study
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Endometrial Cancer, Endometrial Intraepithelial Neoplasia
A Multi-center Prospective Study on the Oncological and Reproductive Outcomes and Quality of Life in Young Woman After Fertility-sparing Treatment of Endometrial Cancer and Endometrial Intraepithelial Hyperplasia
We will investigate the safety and efficiency of fertility-sapring treatment in ypung women witg endometrial cancer and endometrial intraepithelial hyperplasia
- Conditions
- Endometrial Cancer, Endometrial Intraepithelial Neoplasia, Fertility-sparing Surgery
- Trial name
- PreFerEC/EIN (NCT06745427)
- Volunteers
- 100 people
- Sponsor
- Region Stockholm
Breast Cancer
The Young Women's Breast Cancer Study
The investigators are conducting a longitudinal cohort study of young women with breast cancer. The investigators identify women age 40 and younger with newly-diagnosed breast cancer from academic and community healthcare…
- Trial name
- HOHO (NCT01468246)
- Where
- 13 sites in United States, Canada
- Volunteers
- 1,302 people
- Sponsor
- Dana-Farber Cancer Institute
Fertility Issues, Breast Cancer
Effects of Naturalistic Decision-Making Model-based Oncofertility Care Education
his study examined the effects of an oncofertility education program on decisional conflict in nurses caring for breast cancer patients and patients with breast cancer. Other predictors of decisional conflict were also examined.
- Conditions
- Fertility Issues, Breast Cancer, Education
- Trial name
- NCT04600869
- Testing
- Naturalistic Decision-Making Model-based Oncofertility Care Education
- Where
- Taiwan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Mackay Medical College
Fertility Issues
The Combination of Sperm Selection by IMSI and Hyaluronic Acid Binding Assay May Improve ICSI Outcome.
In this prospective randomized sibling-oocytes blinded study, investigators examine the combination of two sperm selection methods that logically seem to complete each other, and potentially may improve ICSI outcomes.
- Trial name
- NCT06156722
- Testing
- Sperm selection by IMSI, Sperm selection by IMSI and spermslow
- Where
- Israel
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Ovarian Cancer
Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation
The "Gonadal Dysgenesis Tissue Cryopreservation for Fertility Preservation" study is open to a subset of patients with disorders of sex development (DSD) which is associated with the risk of malignancy and a high risk of…
- Trial name
- NCT06518746
- Testing
- Cryopreservation of gonadal tissue
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Colorado, Denver
Hypertension, Pulmonary
The Effect of Tracleer® on Male Fertility
The objective of the study is to evaluate the effects of chronic TRACLEER® treatment on testicular function via semen analysis in male patients with primary pulmonary arterial hypertension (PAH).
- Trial name
- NCT00082186
- Testing
- bosentan
- Volunteers
- 22 people
- Sponsor
- Actelion
Fertility Disorders
The Circadian Variability of Serum Progesterone During the Day of a Frozen Embryo Transfer
Serum progesterone levels will be evaluated at four different time points during the day of an artificially prepared frozen embryo transfer cycle (HRT FET cycle) and a modified natural cycle frozen embryo transfer cycle (mNC FET…
- Trial name
- CIRCAPRO (NCT05511272)
- Testing
- blood test
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- Universitair Ziekenhuis Brussel
Morbid Obesity
Bariatric Surgery Outcomes
The UCLA Metabolic and Bariatric Surgery Program (adult program) and the UCLA Fit for Healthy Weight Program (adolescent program) are committed to the care of morbidly obese patients. This study is observational.
- Trial name
- NCT01057784
- Testing
- Bariatric surgery.
- Where
- 2 sites in United States
- Sponsor
- University of California, Los Angeles
Endometrium Cancer, Physical Activity
Effect of Physical Activity Intervention on Overweight and Obese Patients With Endometrial Cancer
This study evaluated the clinical outcome of exercise management on patients with endometrial cancer treated with fertility preservation, including the effect of complete response rate, complete response time, recurrence rate…
- Conditions
- Endometrium Cancer, Physical Activity, Weight Management
- Trial name
- NCT06312917
- Testing
- Physical activity
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Peking University People's Hospital
Sub Fertility, Female, Fertility Disorders
Effects of Fasting on Success Rates of Assisted Reproductive Techologies
This exploratory study investigates fasting as a potential supportive therapy for infertility treatment in women undergoing in-vitro-fertilization (IVF) / intracystoplamsatic sperm injection (ICSI)
- Conditions
- Sub Fertility, Female, Fertility Disorders, Fertility Issues, Sub-fertility
- Trial name
- KiWuC (NCT04998591)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Charite University, Berlin, Germany
Obesity, Overweight
Mazdutide Plus LNG-IUS for Fertility-Sparing Treatment of AEH or Early Endometrial Cancer
This is a prospective, multicenter, randomized, double-blind, placebo-controlled, parallel-group clinical trial designed to evaluate the efficacy and safety of mazdutide combined with a levonorgestrel-releasing intrauterine…
- Conditions
- Obesity, Overweight, Atypical Endometrial Hyperplasia, Endometrial Carcinoma Stage I
- Trial name
- MELIA (NCT07781150)
- Testing
- Mazdutide(Dual GLP-1R/GCGR Agonist), Levonorgestrel-releasing intrauterine system
- Where
- 6 sites in China
- Volunteers
- 128 people
- Sponsor
- Tongji Hospital
Infertility
Diafert for Embryo Selection and Fertility Improvement (DESTINy)
Prospective, single-center, single-blind, randomized, controlled, two-arm, interventional study.
- Trial name
- DESTINy (NCT02593513)
- Testing
- Daifert, Control Group
- Where
- Hungary
- Volunteers
- 108 people
- Sponsor
- Forest Laboratories
Endometriosis
Role of Medical Treatment in Endometriosis Patients Undergoing ICSI
The aim of this study to assess the effect of medical treatment prior to stimulation on fertility (ICSI) outcome in cases with endometriosis associated infertility.
- Trial name
- NCT06577974
- Testing
- Combined contraceptive pills (Yasmin)
- Where
- 2 sites in Egypt
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Cairo University