Clinical trials: Fertility Issues
Azoospermia
GnRHa Combined With hCG and hMG for Treatment of Patients With Non-obstructive Azoospermia
Preliminary reports showed that hormonal treatment may improve the chance of retrieving viable testicular sperm from men with NOA.
- Trial name
- NCT02544191
- Testing
- GnRHa/ hCG/ hMG
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jinling Hospital, China
Infertility, Ovulation Induction
SJ-0021 (Gonalef®) Versus Purified Pituitary Gonadotropin (Fertinorm-P®) for Ovulation Induction in Japanese Infertile Women
Efficacy and safety studies in the past have suggested that a starting dose of 75 International Unit (IU) of SJ-0021, and an increase in the dose by 37.5 IU every 7 days, are safe for treatment of subjects with ovulatory…
- Trial name
- NCT01185782
- Testing
- Gonalef® (Follitropin alfa), Purified pituitary gonadotropin (Fertinorm-P®)
- Where
- Japan
- Volunteers
- 300 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Sterility, Postpartum
Effect of Simethicone on Reducing Bowel Interference During Tubal Resection
Tubal ligation is an everyday procedure for permanent female sterilization. It is usually performed after a vaginal delivery. Minilaparotomy is generally performed by doing small incision at infraumbilical area.
- Trial name
- NCT03429621
- Testing
- Simethicone 80 MG
- Where
- Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chiang Mai University
Peripheral Arterial Disease
Supervised Treadmill Exercise and Ranolazine for Intermittent Claudication of Lower Extremities
The goal of this study is to evaluate whether supervised treadmill exercise combined with ranolazine 1000 mg twice daily provides an incremental benefit in absolute walking distance over supervised exercise alone in patients with…
- Trial name
- STERILE (NCT00914316)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Corewell Health East
STERILITY
Assessment of the Effectiveness and Tolerability of Ovarian Hyperstimulation
The aim of the study is to assess the effectiveness of 5 mixed protocols of ovarian hyperstimulation with urinary gonadotrophins to achieve clinical pregnancy in females undergoing assisted reproductive techniques (IVF/ICSI)…
- Trial name
- DESCARTES (NCT01331720)
- Testing
- hMG-HP
- Where
- 14 sites in Spain
- Volunteers
- 279 people
- Sponsor
- Ferring Pharmaceuticals
Hystrolaparoscopic Findings in Infertile Women With Previous Uterine Surgeries
Hystrolaparoscopic Findings in Infertile Women With Previous Uterine Surgery
1. to determine the rate and pattern of abnormal laparoscopic finding among the infertile women with history of previous uterine surgery. 2.
- Trial name
- NCT06759220
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Polycystic Ovary Syndrome (PCOS)
Blood Vessel Function in Adolescents and Women With Polycystic Ovary Syndrome
The purpose of this study is to determine if changes in blood vessel health lead to the menstrual irregularities that women with PCOS experience.
- Trial name
- NCT01615562
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Infertility
Investigating Micro-Manipulation Procedures for Assisted Hatching Timing
This study aims to assess the clinical significance of cleavage stage (Day 3) assisted hatching compared to assisted hatching at the blastocyst stage (Day 5,6,7) of embryo development at the time of trophectoderm (TE) biopsy for…
- Trial name
- IMPACT (NCT06377917)
- Testing
- Laser Assisted Hatching
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility, Weight Loss
Weight Loss on IVF Outcomes in Overweight and Obese Infertile Women
The aim of this study is to determine whether weight loss prior to in vitro fertilization (IVF) improves live birth outcomes in overweight and obese infertile women.
- Conditions
- Infertility, Weight Loss, Obesity, IVF
- Trial name
- NCT07174817
- Testing
- weight loss
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Peking University People's Hospital
Fertility Disorders, Fertility Issues
Fertility After Uterine Artery Embolization
Uterine leiomyomas (or fibroids) are a common disease (30% of women over 35 years of age) in women of childbearing age and can cause various symptoms such as menometrorrhagia, dysmenorrhoea, pelvic pain and heaviness, and…
- Conditions
- Fertility Disorders, Fertility Issues, Myoma;Uterus, Uterine Artery Embolisation
- Trial name
- FERTI-EMBOL (NCT05271981)
- Testing
- Retrospective data collection, Phone interview
- Where
- France
- Volunteers
- 46 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility
Endometrial Curettage Before Embryo Transfer
Studies have shown that endometrial sampling in the month prior to embryo transfer may increase pregnancy rates. We wish to test this hypothesis by performing a hysteroscopy and curettage in the month proceeding embryo transfer…
- Trial name
- NCT00367367
- Testing
- Hysteroscopy and Curettage
- Where
- Israel
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Unexplained Infertility
Possible Action of Resveratrol in Improving the Outcomes of IVF/ICSI in Couples With Unexplained Infertility
Based on available evidence and given the potential beneficial effects of resveratrol in folliculogenesis and in oocyte development, the investigators designed a randomized, controlled, double-blind, single-center trial, whose…
- Trial name
- RECOS (NCT06481696)
- Testing
- Resveratrol-based multivitamin supplement, Folic acid, IVF/ICSI
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Andros Day Surgery Clinic
Infertility
SU Versus GD for Sperm Preparation in IUI
Intrauterine insemination (IUI) is the first-line treatment for couples with unexplained and mild male factor infertility. The result of IUI depends on many factors including the sperm preparation techniques.
- Trial name
- NCT04477356
- Testing
- SU, DG
- Where
- Vietnam
- Volunteers
- 912 people
- Sponsor
- Mỹ Đức Hospital
Infertility
Progesterone Versus Progesterone Plus Dydrogesterone in FET
Frozen embryo transfer (FET) has been increasing important in IVF. Progesterone is essential for the endometrial secretory transformation, establishment and maintenance of pregnancy.
- Trial name
- MiDRONE (NCT03998761)
- Testing
- Micronized Progesterone, Micronized progesterone plus dydrogesterone
- Where
- Vietnam
- Volunteers
- 1,364 people
- Sponsor
- Mỹ Đức Hospital
Women Infertility
"Magnetic Resonance Imaging Hysterosalpingography for the Integral Evaluation of the Infertile Patient."
Abstract: Recent advances in reproductive medicine have generated a demand for more accurate imaging methods for identifying the specific cause of female infertility and other gynecologic disorders.
- Trial name
- HSG-RM (NCT02398630)
- Testing
- TC Virtual Hysterosalpingography, MRI Virtual Hysterosalpingography, Antimullerian Hormone dosing
- Where
- Argentina
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Diagnostico Maipu
Infertility
Clinical Research Study to Learn About the Effect and Safety of Different Doses of FE 999302 When Given as a Single Dose for Final Development of the Eggs After Ovarian Stimulation
The primary purpose of this trial is to compare three different doses of FE 999302 with 250 µg OVITRELLE and 10,000 IU NOVAREL on oocyte maturity when administered as a single dose for final development of the oocytes in women…
- Trial name
- TIFFANY (NCT05571111)
- Testing
- FE 999302, Ovitrelle, Novarel
- Where
- 3 sites in Spain
- Sponsor
- Ferring Pharmaceuticals
Brain and Central Nervous System Tumors, Chemotherapeutic Agent Toxicity
Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors
RATIONALE: Learning whether temozolomide changes semen or sperm in patients with brain tumors may help doctors learn about the long-term effects of treatment and plan the best treatment.
- Conditions
- Brain and Central Nervous System Tumors, Chemotherapeutic Agent Toxicity, Infertility
- Trial name
- NCT00499798
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Wake Forest University Health Sciences
Primary or Secondary Infertility
Impact of Local Biopsy to the Endometrium Prior to Controlled Ovarian Stimulation on Clinical Pregnancy
In vitro fertilization (IVF) is the only available solution for many couples with various forms of infertility. The embryo implantation step in the IVF procedure is a complex multistage process and represents the majority of the…
- Trial name
- NIDABRECHE (NCT01064193)
- Testing
- biopsy, IVF
- Where
- 3 sites in France
- Volunteers
- 190 people
- Sponsor
- University Hospital, Bordeaux
Anesthesia, Infertility
Sevoflurane Versus Propofol; Neuro Endocrine Response in Patients of Oociyt Pick up
Patients in the study will be grouped as 1st group Propofol, 2nd Group Sevofluran.Preoperative blood will be taken from the patients and cortisol, acth, glucagon, aldosterone, PGE2, CRH will be studied.
- Conditions
- Anesthesia, Infertility, Pain, Postoperative, Stress, Psychological
- Trial name
- NCT03507621
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yavuz Orak
Trapeziometacarpal Osteoarthritis
Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of Trapeziometacarpal Osteoarthritis
The objective of this clinical trial is to evaluate whether a human umbilical cord amniotic membrane allograft can serve as an interposition implant in the surgical treatment of trapeziometacarpal osteoarthritis.
- Trial name
- NCT07435571
- Testing
- with SclerFIX
- Where
- 4 sites in France
- Volunteers
- 22 people
- Sponsor
- TBF Genie Tissulaire