Clinical trials: Fertility Preservation
Amenorrhea, Premature Ovarian Failure
GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients
Primary Objectives: To determine the effectiveness of the 3-month depot leuprolide in inducing and maintaining secondary amenorrhea in patients undergo hematopoietic stem cell transplantation.
- Conditions
- Amenorrhea, Premature Ovarian Failure, Ovarian Function Insufficiency
- Trial name
- NCT00429494
- Testing
- Leuprolide Acetate, Questionnaire, Hematopoietic Stem Cell Transplantation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Fertility Preservation, Breast Cancer
Evaluation of Priming Before in Vitro Maturation for Fertility Preservation in Breast Cancer Patients
Oocyte vitrification after in vitro maturation (IVM) is one of the main techniques for preserving female fertility before chemotherapy for breast cancer.
- Trial name
- PRIMIV (NCT03954197)
- Testing
- No hormone, hCG, GnRH a
- Where
- France
- Volunteers
- 204 people
- Sponsor
- Hôpital Jean Verdier
Fertility Preservation
Oocyte Vitrification for In Vitro Fertilization (IVF) Patients and Women With Fertility Threatening Conditions
Vitrification is a method of cryopreserving tissue for future use. It is widely used to preserve extra, good quality embryos generated from infertility treatments.
- Trial name
- NCT01448460
- Volunteers
- 8 people
- Sponsor
- University of Louisville
Infertility, Female
Physical Activity and Fertility Care Study
Randomized control trial to determine if performing the US Health and Human Services recommended amount of weekly physical activity during ovarian stimulation will differentially affect mental health or clinical outcomes of…
- Trial name
- PACE (NCT04002414)
- Testing
- Sufficient physical activity, Insufficient physical activity
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Endometriosis
Fertility Preservation in Case of Endometriosis
Fertility Preservation is now considered as crucial for the well-being of women battling cancer. However, others indications have more recently emerged.
- Trial name
- PREFENDO (NCT03744754)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endometrial Cancer, Mobile Applications
Application-Assisted Weight Management in Endometrial Cancer Fertility Preservation
This study is a single-center, prospective, randomized controlled trial targeting endometrial cancer (EC) patients undergoing fertility-sparing treatment at Peking University People's Hospital from March 2025 to March 2027.
- Conditions
- Endometrial Cancer, Mobile Applications, Weight Management
- Trial name
- NCT06901778
- Testing
- DEAR weight management, Standardized discharge care plan and follow-up schedule, Implementation of the weight management mobile health application
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Peking University People's Hospital
Ovarian Endometrioma, Endometriosis
Selective Removal of Endometriotic Lesions Using CUSA Clarity in Ovarian Endometriomas
This study aims to evaluate the feasibility and tissue selectivity of a novel surgical technology, the Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity, in the management of ovarian endometriomas.
- Trial name
- CUSA-ENDO (NCT07215130)
- Testing
- Cavitron Ultrasonic Surgical Aspirator (CUSA) Clarity
- Where
- Japan
- Volunteers
- 10 people
- Sponsor
- Kanazawa University
Cervical Cancer
Research on Laparoscopic Fertility-Sparing Surgery in Early-Stage Cervical Cancer
Purpose: To evaluate the oncological and obstetrical outcomes of women with early-stage cervical cancer who underwent laparoscopic-assisted vaginal radical trachelectomy (LAVRT).
- Trial name
- NCT06489171
- Testing
- Received laparoscopic-assisted vaginal radical trachelectomy
- Volunteers
- 132 people
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
Goserelin Acetate Study for Ovarian Function in Patients With Primary Breast Cancer
Primary Objective: To determine the effectiveness of goserelin acetate (Zoladex) in preserving ovarian function in premenopausal women undergoing neoadjuvant and/or adjuvant chemotherapy for primary invasive breast cancer by…
- Trial name
- NCT00429403
- Testing
- Goserelin
- Where
- 2 sites in United States, Japan
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Fertility Preservation
FSH and LH Versus FSH Alone for Ovarian Stimulation in Non-hormone Sensitive Onco-fertility Patients
Fertility preservation has been performed before the initiation of cancer therapy as cancer therapy is known to be toxic for ovarian function.
- Trial name
- NCT06227949
- Testing
- Luveris
- Volunteers
- 140 people
- Sponsor
- Ellen Greenblatt
Fertility Preservation, Alkylating Agents
Efficiency of Gonadotropin-releasing Hormone (GnRH) Agonist in Preventing Chemotherapy Induced Ovarian Failure
Chemotherapy drugs like alkylating agents are frequently used in various combined regimens to treat neoplastic and benign diseases.
- Conditions
- Fertility Preservation, Alkylating Agents, Lymphoma
- Trial name
- Erasme-POF (NCT01160315)
- Testing
- Triptorelin, Norethisterone acetate
- Where
- 15 sites in Belgium, France and 1 more
- Volunteers
- 118 people
- Sponsor
- Erasme University Hospital