Clinical trials: Fetal Development
Chromosome Disorders
Noninvasive Prenatal Diagnosis: Using Fetal Cells From Maternal Blood
This purpose of this study is to develop noninvasive methods of prenatal diagnosis. Fetal cells can be found in maternal blood. This study is designed to isolate these fetal cells from a sample of the pregnant woman's blood and…
- Trial name
- NCT00064597
- Where
- 5 sites in United States
- Volunteers
- 3,500 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pregnancy, Malaria
L-ArGinine to pRevent advErse prEgnancy Outcomes (AGREE)
There are few safe, effective, and affordable interventions to improve pregnancy outcomes in low resource settings where the highest rates of poor birth outcomes occur.
- Conditions
- Pregnancy, Malaria, Nutrition, Placental Development
- Trial name
- AGREE (NCT05934318)
- Testing
- L-citrulline
- Where
- Kenya
- Volunteers
- 2,960 people, healthy volunteers welcome
- Sponsor
- Liverpool School of Tropical Medicine
Pregnancy; Disorder, Blood
Mineral Status in Pregnant Women
Ensuring an adequate supply of nutrients, which include trace elements, is particularly important in pregnancy. Both deficiency and excess of trace elements in the body can interfere with conception and maintaining a healthy…
- Trial name
- PREDISH (NCT03598361)
- Where
- Poland
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Infant Developmental Assessment
The Relationship Between Finger Ratio and Development in Infants
One of the most prominent indicators of prenatal androgen exposure is considered to be the ratio of second and fourth finger lengths (2D:4D).
- Trial name
- NCT07525726
- Testing
- Digit Ratio, Motor development, Sensory processing functions
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Diabetes, Gestational, Insulin Resistance
Metformin in Gestational Diabetes Mellitus
Gestational diabetes (GDM) is a condition that manifests as high blood sugar levels (hyperglycemia) during pregnancy in previously healthy women.
- Trial name
- MetGDM (NCT00681460)
- Testing
- human recombined insulin, metformin
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- K. Marcinkowski University of Medical Sciences
Premature, Orogastric Tube
Development and Efficiency of Atraumatic Orogastric Tube Insertion Protocol with Combination of Wrapping, Fetal Position, Breastmilk, and Sucrose
This study aimed to reduce the pain and increase comfort during the orogastric tube insertion (OGT) procedure, which is routinely applied to feed these babies at 32-34 weeks of age, in preterm newborns with a sucking reflex.In…
- Conditions
- Premature, Orogastric Tube, Oral Sucrose
- Trial name
- OGT (NCT05180058)
- Testing
- Wrapping + Breastmilk Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ayse Sonay Turkmen, Prof.Dr
Telemedicine, Digital Health
Development of an International Remote Digital Care System for Accessible, Inclusive and Sustainable Pregnancy Care
Pregnancy care is under increasing pressure due to a rising number of women needing medical care, a shortage of obstetric healthcare professionals, and growing healthcare costs.
- Conditions
- Telemedicine, Digital Health, Pregnancy Complications
- Trial name
- PregnaDigit EU (NCT07191236)
- Where
- 4 sites in Netherlands, Spain and 1 more
- Volunteers
- 450 people
- Sponsor
- UMC Utrecht
Opioid-Related Disorders
Fetal Neurobehavioral Development in Methadone Maintained Pregnancies
The purpose of this study is to examine differences in fetal neurobehavior at peak (2 hours after oral dose) vs. trough (2 hours before oral dose) maternal plasma methadone levels.
- Trial name
- NCT00067184
- Testing
- Toitu 320/325
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Johns Hopkins University
Educational Problems
Teaching Fetal Development With Virtual Reality
In this study, it was aimed to design virtual pregnancy for pregnancy formation, fetal and placental development in the virtual reality environment and to evaluate the effectiveness of the designed virtual pregnancy on midwifery…
- Trial name
- NCT04444258
- Testing
- Application of computer aided virtual reality glasses, Teaching fetal development theoretically
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Pregnancy Related
Prenatal Analysis of Cell-free Circulating Fetal DNA
In criminal cases involving sexual assault, victims may later discover they are pregnant, creating profound uncertainty about the paternity of the fetus.
- Trial name
- APAFLC (NCT06864806)
- Testing
- Genetic profile
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Fetal Alcohol Spectrum Disorders
Development of an Epigenetic Biomarker for Prediction of Fetal Alcohol Spectrum Disorder
The objective of the study is to validate epigenetic changes as biomarkers in a prospective sampling of newborn blood samples collected at birth (umbilical cord blood) and during routine screening (heel stick blood) in newborns…
- Trial name
- NCT03494738
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- CAMC Health System
Pregnancy
Prenatal Music Exposure to Enhance Postnatal Language Development
The goal of this randomized controlled study is to evaluate the effect of prenatal music exposure on infants through two years of age.
- Trial name
- NCT07699536
- Testing
- High dose music Exposure, Education, Low dose music exposure
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Child Development, Prenatal Stress
Choline Supplementation During Pregnancy: Impact on Attention and Social Withdrawal
The goal is to determine if providing a nutritional supplement, phosphatidylcholine, to pregnant women improves early brain development with improved brain-related development during the first four years of life.
- Trial name
- NCT03028857
- Testing
- Choline
- Where
- 2 sites in United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Medical Termination of Pregnancy, Voluntary Termination of Pregnancy
Mechanisms and Factors Responsible for the Inhibition of Transposons During Fetal Gonad Development in Humans
This is a single-centre study over 36 months for the inclusion of 30 patients. The selection and inclusion of patients will take place according to the criterion of Medical Termination of Pregnancy at 4 different gestational ages…
- Trial name
- NCT02171845
- Testing
- surgical biopsies
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development
Maternal Adversity, Vulnerability and Neurodevelopment
Maternal Adversity Vulnerability and Neurodevelopment (MAVAN) project is a prospective community-based, pregnancy and birth cohort of Canadian mother-child dyads.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Infant Development, Infant Behavior
- Trial name
- MAVAN (NCT03434457)
- Where
- Canada
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Douglas Mental Health University Institute