Clinical trials: Fetal Growth
Fetal Growth Retardation
EVERREST Developing a Therapy for Fetal Growth Restriction
Fetal Growth Restriction (FGR) is a major obstetric problem, affecting 1.46 million fetuses worldwide each year and contributing to 50% of stillbirths.
- Trial name
- EVERREST (NCT02097667)
- Where
- 4 sites in Germany, Spain and 2 more
- Volunteers
- 142 people
- Sponsor
- University College, London
Growth Disorders, Intrauterine Growth Retardation
Genotropin Treatment in Short Prepubertal Children With Intra-Uterine Growth Retardation
To evaluate the effect of continuous and intermittent administration of Genotonorm on stature in short prepubertal children with intra-uterine growth retardation
- Trial name
- NCT01073605
- Testing
- Genotonorm
- Where
- 31 sites in France
- Volunteers
- 208 people
- Sponsor
- Pfizer
Pre-Eclampsia, Fetal Growth Retardation
Doppler and Biological Second Trimester Placental Insufficiency Screening
To assess the role of uterine artery and maternal serum leptin and lipids and their combination in screening for pre-eclampsia and small-for-gestational-age (SGA) fetuses at 20-24 weeks of gestation
- Conditions
- Pre-Eclampsia, Fetal Growth Retardation, Placental Insufficiency
- Trial name
- ARTULEP (NCT00465634)
- Where
- France
- Volunteers
- 235 people
- Sponsor
- University Hospital, Tours
Fetal Growth Retardation
Doppler at the Diagnosis in Predicting Perinatal Outcomes in Early and Late-onset Fetal Growth Restriction
When a FGR is diagnose, the challenge in his monitoring is to assess the benefit-risk balance between continuing the pregnancy in order to limit complications related to prematurity and birth in order to minimize any risk of…
- Trial name
- NCT05696223
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Central Hospital, Nancy, France
Type 2 Diabetes, Pregnancy
Motivational Interviewing With Focus on Diet and Weight Gain in Pregnant Women With Type 2 Diabetes
The primary goal of this case control study is to investigate the effect of implementation of motivational interviewing with focus on diet and weight gain in addition to the routine treatment on prevention of excessive…
- Trial name
- NCT02883127
- Testing
- Motivational interviewing
- Where
- Denmark
- Volunteers
- 189 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pregnancy, Pregnancy Complications
AI-POCUS for Maternal and Neonatal Health in Ethiopia
Maternal and neonatal health remains one of the most pressing global health challenges, particularly in low- and middle-income countries (LMICs).
- Conditions
- Pregnancy, Pregnancy Complications, Preterm Birth, Fetal Growth Restriction
- Trial name
- AIM-ETH (NCT07171086)
- Testing
- AI-POCUS (BabyChecker, Delft Imaging), AI-POCUS (Edan, China)
- Where
- Ethiopia
- Volunteers
- 1,059 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
Fetal Growth Restriction (FGR), Placental Insufficiency
Placental Imaging Techniques
The goal of this proof-of-concept, case-control, clinical trial is to evaluate the efficacy of using two newer ultrasound technologies, quantitative ultrasound (QUS) and ultrafast power Doppler imaging (uPDI), to evaluate the…
- Conditions
- Fetal Growth Restriction (FGR), Placental Insufficiency, Preeclampsia, Still Births
- Trial name
- NCT06861309
- Testing
- ultrafast power Doppler imaging (uPDI) / quantitative ultrasound (QUS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Carilion Clinic
Congenital Heart Disease, Pregnancy Complications
Fetal Growth and Pregnancy Complications Among Women With Heart Disease
An increasing proportion of women with heart disease now go through pregnancy and childbirth. More knowledge about the risk of complications and adverse outcomes for the mother and the baby is needed to guide clinical care in…
- Conditions
- Congenital Heart Disease, Pregnancy Complications, Arrhythmias, Cardiac, Hypertension in Pregnancy
- Trial name
- PreCor (NCT03657823)
- Where
- Norway
- Volunteers
- 800 people
- Sponsor
- Oslo University Hospital
Inflammation, Obesity
Omega-3 Supplementation Decreases Inflammation and Fetal Obesity in Pregnancy
Randomized, double-blind placebo controlled trial of fish oil to decrease inflammation in pregnancy.
- Conditions
- Inflammation, Obesity, Pregnancy, Fetal Growth
- Trial name
- NCT00957476
- Testing
- Omega-3 Fish Oil
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Hypoglycemia Non-Diabetic, Gastric Bypass Status Complicating Pregnancy, Birth, or Puerperium
Bariatric Surgery and Consequences for Mother and Baby in Pregnancy
Background Roux-en-Y gastric bypass (RYGB) is a well-established treatment of obesity, most often performed in women during their reproductive years. Adverse events related to RYGB include hypoglycemia.
- Trial name
- BAMBI (NCT03713060)
- Testing
- Mixed meal test
- Where
- 2 sites in Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Fetal Growth Restriction (FGR)
Observational Study on Fetal Growth Restriction Complicated by Early Flowmetric Alterations
The goal of this observational study is to to understand whether the presence of flowmetric alterations in association with early growth retardation (i.e., before 22 weeks gestational age) is associated with worse neonatal and…
- Trial name
- ARDEF (NCT06717555)
- Where
- Italy
- Volunteers
- 63 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Fetal Growth Retardation, Low Birth Weight
BEP Supplementation Research in Bangladesh (JiVitA-BEP-IR)
The primary aim of the study is to evaluate the effect of fortified balanced energy and protein (BEP) supplementation vs. control (multiple micronutrient supplement, MMS) without targeting and with targeting (either by low…
- Conditions
- Fetal Growth Retardation, Low Birth Weight, Preterm Birth, Gestational Weight Gain
- Trial name
- Target-BEP (NCT05576207)
- Testing
- Balanced energy and protein supplement for pregnant women, Multiple Micronutrient Supplement for pregnant women
- Where
- Bangladesh
- Volunteers
- 3,390 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Low Birth Weight Infants
Alkaline Phosphatase Level in Pregnancy and Its Association With Birth Weight
Alkaline phosphatase is known to be produced by syncytiotrophoblasts in the placenta and its levels are normally increased in pregnancy.
- Trial name
- NCT03187938
- Testing
- Testing of Alkaline Phosphatase Levels
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Preterm Birth, Pregnancy
Fetal Anatomy by Three-Dimensional Ultrasound
A major goal of perinatal care is to accurately diagnose fetal anomalies prior to birth. This capability allows clinicians to make prudent decisions regarding antepartum care, delivery site, and postnatal therapy.
- Conditions
- Preterm Birth, Pregnancy, Fetal Growth Abnormalities
- Trial name
- NCT00340002
- Where
- 2 sites in United States
- Volunteers
- 3,650 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Fetal Growth Retardation
Prediction of Placental Fetal Growth Restriction in High Risk Population (PoPFGR)
This study intends to prospectively enroll high-risk pregnant women to establish a multicenter cohort. By combining maternal basic characteristics, medical history, early pregnancy ultrasound, and biological markers, we aim to…
- Trial name
- NCT06096805
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Premature Birth, Premature Infant
Growing Little PEAPODS Study
The goal of this clinical trial is to learn more about how the food and nutrition babies receive while in the Neonatal Intensive Care Unit (NICU) influences their ability to gain weight and fat-free mass, and their future growth…
- Conditions
- Premature Birth, Premature Infant, Premature, Intrauterine Growth Restriction
- Trial name
- NCT06226051
- Testing
- PEAPOD Infant Body Composition measuring device
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Wisconsin, Madison
Hypertension, Pregnancy-Induced, HELLP Syndrome
PROTECT-Africa: Biomarker Validation for Preeclampsia Triage
Preeclampsia is a serious high blood pressure condition that can develop during pregnancy. It is one of the leading causes of death and illness for mothers and babies in Africa.
- Conditions
- Hypertension, Pregnancy-Induced, HELLP Syndrome, Eclampsia, Fetal Growth Retardation
- Trial name
- PROTECT-Africa (NCT07810439)
- Where
- Zimbabwe
- Volunteers
- 1,106 people
- Sponsor
- Africa Clinical Research Network (ACRN)
Anemia, Intrauterine Growth Retardation
Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child Outcomes
The study evaluates the efficacy of providing weekly iron-folate (IFA) supplements or Multiple Micronutrient (MM) supplements before pregnancy in increasing birth weight and duration of gestation as well as maternal and infant…
- Conditions
- Anemia, Intrauterine Growth Retardation, Preterm Delivery, Iron Deficiency
- Trial name
- NCT01665378
- Testing
- Multiple Micronutrient, Iron and Folic Acid, Folic Acid
- Where
- Vietnam
- Volunteers
- 5,011 people, healthy volunteers welcome
- Sponsor
- Emory University
Umbilical Cord Issue, Intrauterine Growth Restriction
Three-dimensional Umbilical Cord Coiling Index
Previous studies have shown that abnormal coiling of the umbilical cord is associated with adverse perinatal outcome. For example, an umbilical cord that is non-coiled increases the chance of fetal morbidity and mortality…
- Conditions
- Umbilical Cord Issue, Intrauterine Growth Restriction, Fetal Distress
- Trial name
- NCT05727241
- Testing
- Ultrasound
- Where
- Israel
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Fetal Growth Retardation
Non-invasive Placental Chromosome Exploration of Intrauterine Growth Restriction
The objective of this project is the non-invasive prenatal detection of placenta-limited aneuploidies, in patients whose fetuses have a intrauterine growth restriction below 3rd percentile, in parallel with an amniocentesis.
- Trial name
- DPNI-RCIU (NCT05023161)
- Testing
- Blood samples
- Where
- 3 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bordeaux