Clinical trials: Fetal Growth
Preterm Labor, Maternal Psychological Distress
Fetal Brain Growth - Pilot Study
The goal of this observational prospective study is to explore the feasibility of measuring fetal and neonatal brain growth using 2D and 3D ultrasound in fetuses exposed to threatened preterm labor (TPTL) and antenatal…
- Trial name
- NCT05994443
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Fetal Growth Retardation
Placental Lesions in Fetal Growth Restrictions
The purpose of this research study is to develop imaging methods to diagnose placental injury in pregnancies diagnosed with fetal growth restriction (FGR).
- Trial name
- NCT04839185
- Testing
- Ferumoxytol infusion, MRI scan
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Wisconsin, Madison
Pre-eclampsia, Oocyte Donation
PRIOR Study (Pre-eclampsia Risk In Oocyte Recipients)
The aim of this prospective observational cohort study is to investigate the pathophysiological mechanisms behind and risk of pre-eclampsia in women pregnant after fertility treatment with oocyte donation.
- Conditions
- Pre-eclampsia, Oocyte Donation, Pre-Eclampsia; Complicating Pregnancy, Pre-Eclampsia; Mild
- Trial name
- PRIOR (NCT07263490)
- Where
- 6 sites in Denmark
- Volunteers
- 462 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Pregnancy Related
Effects of Snakehead Fish on IUGR and LBW Among Second and Third Trimester Women
This study uses a Randomized Controlled Trial (RCT) design, conducted on pregnant women in Yogyakarta Province, Indonesia. This study aims to observe the effects of snakehead fish prepared-meal intervention on fetal growth…
- Trial name
- NCT07005609
- Testing
- Snakehead fish meal
- Where
- Indonesia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gadjah Mada University
Fetal Growth Restriction
Prostaglandins Versus Trans-cervical Balloon for Induction of Labor in Fetal Growth Restriction (PROBIN)
The goal of this randomized trial is to compare two methods of induction in a fetal growth restriction population. The main question it aims to answer is: Is trans-cervical balloon superior to prostaglandins in reducing the…
- Trial name
- PROBIN (NCT05674487)
- Testing
- Trans-cervical balloon, Misoprostol
- Where
- France
- Volunteers
- 774 people
- Sponsor
- University Hospital, Bordeaux
Preterm Labor, Preterm Birth
MIRACLE of LIFE Study
The goal of this observational study is to develop and validate cell-free RNA-based biomarkers for predicting a variety of adverse pregnancy outcomes in a pregnant person population. The main question it aims to answer are: 1.
- Conditions
- Preterm Labor, Preterm Birth, Preterm Birth Complication, Preterm Premature Rupture of Membrane
- Trial name
- MoL (NCT06074601)
- Testing
- Mirvie Predictive Test for Adverse Pregnancy Outcomes
- Where
- 10 sites in United States
- Volunteers
- 10,000 people
- Sponsor
- Mirvie
Hydrops Fetalis, Fetal Growth Retardation
Amniotic Fluid Tandem Mass Spectrometry for Pregnancies Complicated by NIH and Severe Symmetrical IUGR
The objective of this pilot study is to prospectively evaluate amniotic fluid of pregnancies complicated by non-immune hydrops and severe symmetrical intrauterine growth restriction by tandem mass spectrometry for inborn errors…
- Trial name
- TandemMS (NCT00143039)
- Testing
- Tandem MS test for inborn errors of metabolism
- Where
- 11 sites in United States
- Volunteers
- 48 people
- Sponsor
- Obstetrix Medical Group
Healthy
Fetal Aortic Pulsewave Velocity: A Novel Doppler Ultrasound Method of Measuring the Biophysical Properties of the Fetal Aorta
We are interested in determining if we can measure the blood flow in the descending aorta (large blood vessel in the abdomen) of healthy fetuses and fetuses with growth restriction. An increasing number of adult diseases (e.g.
- Trial name
- NCT00359034
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Intra Uterine Growth Retardation
The Relationship Between Second Trimester Placental Growth Factor Level and Fetal Growth Restriction
Type of the study: A prospective observational study Study settings: The study will be conducted at Ain Shams University Maternity Hospital, Obstetrics and Gynecology Department, Faculty of medicine over a period of six month…
- Trial name
- NCT03350399
- Testing
- placenta growth factor
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- amera mohamed
Pregnancy Complications
Measuring sVAP-1 as a Predictor of Pregnancy Problems
Pre-eclampsia is a common pregnancy disorder defined as high blood pressure and protein in the urine after 20 weeks of pregnancy.
- Trial name
- NCT04891315
- Testing
- Blood test for soluble VAP-1 (sVAP-1).
- Where
- United Kingdom
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Leicester
Fetal Macrosomia, Congenital Abnormality
Fish Oil Supplementation in Women With Gestational Diabetes
Gestational diabetes is the development of diabetes during pregnancy. Left untreated, gestational diabetes and preeclampsia can lead to serious -- or even fatal -- complications for both mother and child.
- Conditions
- Fetal Macrosomia, Congenital Abnormality, Other Respiratory Problems After Birth
- Trial name
- NCT02371343
- Testing
- Fish oil, Ocean plus, Sunflower Oil
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dr. Sami Ulus Children's Hospital
COVID-19, COVID-19 Pneumonia
Effect of Covid 19 Infection on Fetomaternal Outcome
The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was discovered for the first time in December 2019 in Wuhan (China) and the disease it causes is called coronavirus disease 2019…
- Conditions
- COVID-19, COVID-19 Pneumonia, Fetal Growth Retardation
- Trial name
- NCT05160649
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University
Uncomplicated Pregnancy, Abnormal Fetal Growth or Fluid
Determination of Abnormal Fetal Growth or Amniotic Fluid With Third Trimester Ultrasounds in Uncomplicated Pregnancies: A Randomized Trial
The purpose of this study is to see whether women at a gestational age of 30 weeks or more without comorbidities, does performance of serial 3rd trimester growth ultrasounds increase the frequency of identifying abnormalities in…
- Trial name
- UP (NCT02702999)
- Testing
- Clinically-indicated ultrasound, Serial third trimester ultrasound
- Where
- 2 sites in United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Fetal Growth Retardation
Can Low Molecular Weight Heparin During Pregnancy With Intrauterine Growth Restriction Increase Birth Weight?
The purpose of the study is to investigate if treatment with an anticoagulant drug increases birth weight in pregnancies complicated by fetal growth restriction.
- Trial name
- IUGR (NCT01390051)
- Testing
- Innohep (Tinzaparin), tinzaparin
- Where
- 3 sites in Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Preterm Birth, Low Birth Weight
Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in Newborns
This study focuses on understanding the conditions that affect newborn health and survival from pregnancy to the first weeks of life at the Isidro Ayora Hospital.
- Conditions
- Preterm Birth, Low Birth Weight, Intrauterine Growth Restriction (IUGR), Perinatal Asphyxia
- Trial name
- UCE (NCT06653374)
- Testing
- Infant, Premature
- Where
- Ecuador
- Volunteers
- 26,000 people
- Sponsor
- HOSPITAL GINECO OBSTETRICO ISIDRO AYORA
Intrauterine Growth Restriction (IUGR)
Determination of Clinical Phenotypes of Intrauterine Growth Restriction in Term Infants Based on Body Composition
Intrauterine growth restriction (IUGR) is defined as the inability of the fetus to fulfill its genetic growth potential. "Small for gestational age" (SGA) is the most commonly used indicator for diagnosing IUGR.
- Trial name
- Restrigrowth (NCT07483424)
- Testing
- Small for gestational age (SGA) infants, Adequate for gestational age (AGA) infants
- Where
- Portugal
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar de Lisboa Central
Obstructive Sleep Apnea, Pregnancy
Auto-PAP Therapy For Improved Fetal Growth
The purpose of this study is to see whether the presence of night-time breathing disturbances ("sleep-disordered breathing") in pregnant women is related to fetal growth patterns.
- Trial name
- NCT03318003
- Testing
- Auto-PAP
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Michigan
Infant Malnutrition, Fetal Growth Retardation
DEUX OEUFs: Cracking the Potential of Eggs to Improve Child Growth and Development
This proposed randomized controlled trial aims to investigate the effect of maternal egg consumption during pregnancy on birth length.
- Trial name
- NCT06405360
- Testing
- Egg consumption
- Where
- Rwanda
- Volunteers
- 464 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pregnancy, Fetal Macrosomia
Correlation Between Placental Thickness in the Second and Third Trimester and Fetal Weight
The aim of this prospective longitudinal study was to investigate the relationship between placental thickness during the second and third trimesters and placental and birth weights.
- Conditions
- Pregnancy, Fetal Macrosomia, Intrauterine Growth Restriction
- Trial name
- NCT02473991
- Testing
- ultrasound
- Where
- Egypt
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Pre-Eclampsia, Pre-Term
Vascular Inflammation and Anti-inflammatory Supplements After Adverse Pregnancy Outcomes
Women who had an adverse pregnancy outcome (APO), such as preeclampsia, preterm birth, or gestational diabetes, have a higher risk for heart disease.
- Conditions
- Pre-Eclampsia, Pre-Term, Intrauterine Growth Restriction, Hypertension in Pregnancy
- Trial name
- VIA (NCT04633551)
- Testing
- Anti-inflammatory supplement
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of South Carolina