Clinical trials: Fetal Growth
Fetal Growth Retardation
Cook´s Balloon Versus Dinoprostone for Labor Induction of Term Pregnancies With Fetal Growth Restriction
The goal of this clinical trial is to compare how two methods for cervical ripening work in a population of singleton pregnancies with late-onset fetal growth restriction (FGR) at term.
- Trial name
- COLIGROW (NCT05774236)
- Testing
- Cook´s balloon, Vaginal dinoprostone
- Where
- 5 sites in Spain
- Volunteers
- 172 people
- Sponsor
- Hospital Universitario 12 de Octubre
Gestational Diabetes
Oral Antidiabetic Agents in Pregnancy
The aim of this study is to determine the efficacy of oral treatment with glyburide and metformin controlling excessive fetal growth in women with gestational diabetes, using insulin as a ransom on no response to oral treatment .
- Trial name
- NCT02091336
- Testing
- Metformin, Glyburide
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Fetal Growth Retardation
Fetal Genome Profiling Via Trophoblast Cells
The objective of this study is to utilize trophoblast cells accumulating in the endocervical canal at the beginning of pregnancy for non-invasive prenatal testing.
- Trial name
- NCT03832634
- Testing
- Fetal Genome Profiling.
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pregnancy, Fetal Growth
The National Standard for Normal Fetal Growth
Normal fetal growth is a critical component of a healthy pregnancy and the long-term health of the offspring. Pivotal to understanding the dynamics of human fetal growth and to defining normal and abnormal fetal growth is the…
- Trial name
- NCT00912132
- Where
- 11 sites in United States
- Volunteers
- 2,802 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Normal Pregnancies
The Impact of Placental Factors on Fetal Intrauterine Growth and in Intrauterine Programming of the Metabolic Syndrome
Genetic and environmental factors are believed to play a major role in intrauterine growth and intrauterine programming. We intend to study genetic factors such as Telomere homeostasis, senescence, genomic instability and the…
- Trial name
- NCT01883154
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Meir Medical Center
Pediatric Health, Growth & Development
Ewha Birth and Growth Study (Birth Cohort)
The Ewha Birth and Growth Study is a prospective birth cohort established at Ewha Womans University Mokdong Hospital in Seoul, Republic of Korea.
- Conditions
- Pediatric Health, Growth & Development, Cardiometabolic Health
- Trial name
- NCT03351595
- Where
- South Korea
- Volunteers
- 940 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Twin Pregnancy
Twins With Specific vs. Traditional Fetal Growth Charts
This study aims to compare how well two different types of fetal growth charts work in tracking the growth of twins during pregnancy. These charts help doctors decide if a fetus is growing normally.
- Trial name
- TWiST (NCT07164001)
- Testing
- Twin-Specific Growth Chart Interpretation, Singleton-Based Growth Chart Interpretation
- Volunteers
- 150 people
- Sponsor
- Indiana University
Intrauterine Growth Restriction, Preeclampsia
Low Dose Aspirin for Preventing Intrauterine Growth Restriction and Preeclampsia in Sickle Cell Pregnancy (PIPSICKLE)
Pregnancy in sickle cell disease (SCD) is fraught with many complications including preeclampsia (PE) and intrauterine growth restriction (IUGR).
- Conditions
- Intrauterine Growth Restriction, Preeclampsia, Sickle Cell Disease, Pregnancy Complications
- Trial name
- PIPSICKLE (NCT05253781)
- Testing
- Low-dose aspirin
- Where
- 16 sites in Nigeria
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- University of Lagos, Nigeria
Fetal Growth Restriction
A Randomized Air Filter Intervention Study of Air Pollution and Fetal Growth in a Highly Polluted Community
The purpose of this study is to use an air filter intervention to evaluate the relationship between particulate matter air pollution exposure during pregnancy and fetal growth.
- Trial name
- NCT01741051
- Testing
- HEPA Filter
- Where
- Mongolia
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Pregnancy
Fetal Growth Evaluation by Three-Dimensional Ultrasound
Fetal growth abnormalities, such as macrosomia and intrauterine growth retardation, are an important cause for increased perinatal mortality in the United States.
- Trial name
- NCT00340171
- Where
- 2 sites in United States
- Volunteers
- 1,919 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Infant Malnutrition, Light-For-Dates With Signs of Fetal Malnutrition
Early DHA/ARA Supplementation in Growth-restricted Very Preterm Infants: A Randomized Clinical Trial
Growth-restricted very preterm infants (VPT) are born without adequate fat mass (FM) deposits and low docosahexaenoic acid (DHA) concentrations.
- Conditions
- Infant Malnutrition, Light-For-Dates With Signs of Fetal Malnutrition, Premature, Nutrition Disorder, Infant
- Trial name
- NCT06207071
- Testing
- DHA
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Intrauterine Growth Retardation (IUGR)
Reproducibility of the Measurement of the Right Portal Vein Diameter
Although routine ultrasound is offered during the third trimester of pregnancy, less than a quarter of newborns with intrauterine growth retardation (IUGR) are suspected antenatally.
- Trial name
- PORTALGROWTH1 (NCT04617964)
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Intrauterine Growth Restriction
The Effect of Oral Isosorbide Mononitrate Therapy on Umbilical Artery Doppler Resistance Index in Pregnancies With Intrauterine Growth Restriction: Prospective Randomized Control Trial
Will follow up umblical artery Doppler indices for pregnancies with iugr taking placebo and oral isosorbide mononitrate to study its efficacy on the intrauterine growth restricted fetuses
- Trial name
- NCT05800938
- Testing
- Isosorbid mononitrate
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Fetal Growth Retardation
Doppler and AFV for Outcome Prediction ın FGR
The investigator contrived a prospective study of AUCR to compare its association to adverse perinatal outcomes with other established doppler parameters, such as CPR and UCR within a population of suspected FGR fetuses at term.
- Trial name
- NCT05295667
- Testing
- Doppler measurement in combination with amniotic fluid volume
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Bakirkoy Maternity and Children Diseases Hospital
Fetal Growth Retardation
Low-molecular-weight Heparin in Constituted Vascular Intrauterine Growth Restriction
Intrauterine growth restriction (IUGR) is correlated to an abnormal placenta development, with an alteration of the maternal-fetal circulation, coagulation troubles, and apparition of placental infarcts.
- Trial name
- GROWTH (NCT02672566)
- Testing
- Enoxaparin, Usual care
- Where
- 8 sites in France
- Volunteers
- 82 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pre-eclampsia, Gestational Diabetes Mellitus (GDM)
Placental Biology in Health and Disease
Pre-eclampsia (PET) is a condition characterised by high blood pressure and damage to other organs, and is a leading cause of maternal and fetal complications such as fetal growth restriction (FGR).
- Conditions
- Pre-eclampsia, Gestational Diabetes Mellitus (GDM), Fetal Growth Restriction (FGR), Pregnancy Induced Hypertension (PIH)
- Trial name
- NCT07470320
- Testing
- There are no interventions for this study
- Where
- United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Obstetric Complication, Ultrasound
The Utility of Customised Growth Charts for Identifying Macrosomia and the Effect of Intervention
Best management of suspected large for gestational age (LGA) fetuses is unclear. In some hospitals women with an LGA fetus by customised growth charts are are offered earlier induction.
- Conditions
- Obstetric Complication, Ultrasound, Induction of Labor Affected Fetus / Newborn, Fetal Growth Complications
- Trial name
- NCT04536753
- Testing
- Induction of labour
- Where
- United Kingdom
- Volunteers
- 845 people
- Sponsor
- Newcastle University
Umbilical Artery Doppler, Fetal Heart Rate Tracing
Mobile Phone Effects on Umbilical Artery Doppler and Heart Rate Tracing
Women were instructed not to use the mobile phones for 24 hours before carrying out the initial CTG trace and Doppler ultrasound.
- Trial name
- NCT02445261
- Testing
- mobile phone
- Where
- 2 sites in Egypt
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Cairo University
Isolated Intrauterine Growth Restriction (IUGR)
Assessment of Invasive Genetic Testing in Fetuses With Isolated Intrauterine Growth Restriction Diagnosed After 28 Weeks of Gestation at Strasbourg University Hospitals (2016-2023)
This study evaluates the diagnostic yield of invasive genetic testing in fetuses with isolated intrauterine growth restriction diagnosed after 28 weeks of gestation, in order to better define indications for invasive procedures…
- Trial name
- RCIU (NCT07864272)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Obesity, Pregnancy
Sleep Apnea, Obesity and Pregnancy
Main objective: Determine the prevalence of obstructive sleep apnea syndrome (OSA) in late pregnancy in a population of obese patients .
- Trial name
- GOS (NCT02029859)
- Testing
- Polygraphic examination
- Where
- 4 sites in France
- Volunteers
- 205 people
- Sponsor
- University Hospital, Rouen