Clinical trials: Fetal Outcomes
Prevention of Vitamin Deficiency During and/or Before Pregnancy
A Study to Gather Information About the Progress and Outcomes of Pregnancy in Women Using Various Vitamin Support Plans Before and During Pregnancy
This is an observational study in which data from the participants who will be taking different vitamin supplementation regimes before and during pregnancy.
- Trial name
- NCT05062044
- Testing
- Multivitamins (Elevit, BAY987808), Multivitamins (Elevit, BAY2906300), Multivitamins (Elevit, BAY987386)
- Where
- 3 sites in Kazakhstan, Russia and 1 more
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Bayer
Preeclampsia
Fetal Renal Artery Doppler in Patients With Preeclampsia
Preeclampsia is a major devastating disorder affects 2:10% of pregnancies worldwide. preeclampsia may be associated with placental insufficiency which may cause fetal blood redistribution to essential organs like brain, heart…
- Trial name
- NCT06395974
- Testing
- fetal ultrasound
- Where
- Egypt
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Assiut University
Fetal Infection, Fetal Inflammatory Response Syndrome
IL-6 and Lactates in Cord Blood and Neonatal Outcomes
The goal of this observational study or clinical trial is to evaluate interleukin-6 (IL-6) and lactate levels in maternal and cord blood to identify early signs of fetal inflammation or infection.
- Conditions
- Fetal Infection, Fetal Inflammatory Response Syndrome, Chorioamnionitis, Chorioamnionitis Affecting Fetus or Newborn
- Trial name
- ECCO-IL6 (NCT07211503)
- Testing
- blood sampling
- Where
- Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Labor Complication
Uterine Artery Pulsatility Index and Materno Fetal Outcomes
High Uterine artery index pulsatility (PI) is associated with small for gestationnal age but also with stillbirth and distress during labor.
- Trial name
- UADLAB (NCT02853058)
- Testing
- normal PI, pathological PI
- Where
- Tunisia
- Volunteers
- 600 people
- Sponsor
- University Tunis El Manar
Opioid-use Disorder, Pregnancy Related
STEPuP: Prenatal Provider Education and Training to Improve Medication-assisted Treatment Use During Pregnancy
This research will test the effectiveness of a prenatal provider education and training program designed to facilitate provider adoption of evidence-based practices for the treatment of OUD during pregnancy.
- Trial name
- STEPuP (NCT04527926)
- Testing
- STEPuP Intervention, Usual Care
- Where
- United States
- Volunteers
- 1,022 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Nutrition During Pregnancy
PREnatal Choline and Infant Outcomes Study
Less than 10% of pregnant women consume adequate levels of choline, an essential nutrient for maternal lipid metabolism, placental efficiency, and fetal development.
- Trial name
- PRECIOUS (NCT07525193)
- Testing
- Choline nutrition education (CNE)
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Amniocentesis Affecting Fetus
Outcomes of Children in Whom a Prenatal Exome Was Performed Based on Ultrasound Findings
Amniocentesis is a test offered to couples based on ultrasound findings during pregnancy. Currently, genetic analysis using FISH and ACPA is routinely performed.
- Trial name
- ExoPré (NCT07342933)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Strasbourg, France
Incontinence, Urinary, Training Group, Sensitivity
Prenatal Pilates Assisted Childbirth Preparation Training and Incontinence
A randomized controlled trial was made to determine the effectiveness of prenatal pilates-supported childbirth preparation training on birth outcomes, incontinence during pregnancy, and the postpartum period.
- Trial name
- NCT06185439
- Testing
- Prenatal Pilates Assisted Childbirth Preparation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Rupture of Membranes; Premature, Distress; Fetal, Complicating Delivery
PeRinatal Outcomes With ACTive Versus Expectant Management of Women With Pre-labor Rupture Of Membranes
Term pre-labor rupture of membranes (PROM) occurs in about 12% of pregnancies and the time between PROM and delivery increases the risk of maternal/fetal infections.
- Conditions
- Rupture of Membranes; Premature, Distress; Fetal, Complicating Delivery, Delayed Delivery After Spontaneous or Unspecified Rupture of Membranes, Maternal Sepsis
- Trial name
- PROACT PROM (NCT05958953)
- Testing
- Induction of Labor IoL
- Where
- Italy
- Volunteers
- 1,400 people
- Sponsor
- University of Modena and Reggio Emilia
Infertility, Aneuploidy
Single Embryo TrAnsfeR of Euploid Embryo
The purpose of the current study is to evaluate the effect of preimplantation genetic screening (PGS) by next generation sequencing (NGS) compared to standard morphological assessment of embryos on pregnancy rates through a…
- Trial name
- STAR (NCT02268786)
- Testing
- Preimplantation Genetic Screening by NGS
- Where
- 38 sites in United States, Australia and 2 more
- Volunteers
- 661 people
- Sponsor
- Illumina, Inc.
Prenatal Education Program, Indivisible Self Model
The Psychosocial Effects of Prenatal Education With the Indivisible Self Model
This study was designed to compare the effects of a prenatal education program based on the Indivisible Self Model with those of a needs-based prenatal education program on psychosocial outcomes among pregnant women.
- Conditions
- Prenatal Education Program, Indivisible Self Model, Salutogenic Approach
- Trial name
- NCT07699900
- Testing
- Prenatal Education Program Based on the Indivisible Self Model, The needs-based prenatal education program
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Mersin University
Pregnancy, Premature Birth
Development of a Nationally Scalable Model of Group Prenatal Care to Improve Birth Outcomes: "Expect With Me"
This study addresses the intractable challenges of adverse birth outcomes, including preterm delivery and low birthweight, by proposing the development, implementation and evaluation of a model of group prenatal care that could…
- Conditions
- Pregnancy, Premature Birth, Infant, Low Birth Weight, Postpartum Period
- Trial name
- NCT02169024
- Testing
- Expect With Me group prenatal care, Standard individual prenatal care
- Where
- 2 sites in United States
- Volunteers
- 2,402 people, healthy volunteers welcome
- Sponsor
- Yale University
PROM, Preterm (Pregnancy)
Novel Use of Central Venous Pressure (CVP) Set With McDonald Cerclage Technique for Amnioinfusion in Preterm Premature Rupture of Membranes Improves Amniotic Fluid Index and Neonatal Outcomes
This prospective, two-arm, non-randomized comparative interventional study evaluated the effectiveness of amnioinfusion using a central venous pressure (CVP) set compared with conventional transabdominal amnioinfusion in pregnant…
- Trial name
- CAM-PPROM (NCT07774832)
- Testing
- CVP-Set Amnioinfusion With McDonald Cerclage, Conventional transabdominal amnioinfusion
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Herlambang Herlambang
Hydrops Fetalis, Birth Defect
Hydrops: Diagnosing & Redefining Outcomes With Precision Study
This is a national, prospective study designed to investigate the genetic etiologies of non-immune hydrops fetalis (NIHF) and other birth defects.
- Conditions
- Hydrops Fetalis, Birth Defect, Fetal Anomaly
- Trial name
- HyDROPS (NCT03412760)
- Testing
- Exome sequencing
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of California, San Francisco
Instrumental Delivery; Nec, Affecting Fetus or Newborn
Neonatal Outcomes in Instrumental Delivery
The aim of this study is to compare the impact of instrumental delivery on newborn head mark and newborn comfort over the impact of non-instrumental delivery.
- Trial name
- NCT03337880
- Testing
- instrumental delivery
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Poitiers University Hospital
Premature Birth
Social Networking on Mobile Phone to Improve Maternal and Neonatal Outcomes
The purpose of the study is to determine whether social networking on mobile phone in antenatal care health education is effective in the improvement of maternal and neonatal outcomes compared with usual antenatal care.
- Trial name
- HISONET (NCT02371213)
- Testing
- social networking on mobile phone
- Where
- Thailand
- Volunteers
- 1,160 people
- Sponsor
- Nopparatrajathanee Hospital
Antenatal Care
Group Antenatal Care and Delivery Project
Antenatal care (ANC) has the potential to play a pivotal role in ensuring positive pregnancy outcomes for both mothers and their newborns.
- Trial name
- GRAND (NCT04033003)
- Testing
- Group ANC
- Where
- 14 sites in Ghana
- Volunteers
- 1,761 people
- Sponsor
- University of Michigan
Chronic Idiopathic Constipation (CIC)
Post-Marketing Study of Prucalopride Safety In Pregnancy
This study collects information on pregnant women with ongoing constipation who took prucalopride and those who did not take prucalopride.
- Trial name
- NCT04869280
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Takeda
Hypertensive Disorder of Pregnancy, Sleep Apnea, Obstructive
Positive Airway Pressure Treatment of Obstructive Sleep-disordered Breathing in Hypertensive Disorders of Pregnancy
The purpose of this study is to conduct a pilot randomized, controlled trial to evaluate the feasibility and obtain pilot outcome data for a subsequent definitive trial evaluating the effects of postitive airway pressure (PAP)…
- Trial name
- NCT03309826
- Testing
- Positive Airway Pressure, Nasal Dilator Strip
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Dr John Kimoff
Fetal Growth Retardation
Doppler at the Diagnosis in Predicting Perinatal Outcomes in Early and Late-onset Fetal Growth Restriction
When a FGR is diagnose, the challenge in his monitoring is to assess the benefit-risk balance between continuing the pregnancy in order to limit complications related to prematurity and birth in order to minimize any risk of…
- Trial name
- NCT05696223
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Central Hospital, Nancy, France