Clinical trials: Fetus Fetus
Induction of Labor Affected Fetus / Newborn, Pregnancy Late
Effect of Maternal Age and BMI on Induction of Labor Using Oral Misoprostol in Late-term Pregnancies: a Retrospective Cross-sectional Study
To evaluate the effect of maternal age and body mass index (BMI) on oral misoprostol induction of labor for late-term pregnancies.
- Trial name
- NCT06184139
- Testing
- Misoprostol
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- University of Palermo
Pregnancy
Development of a Non-invasive Prenatal Test
This is an observational study to aid in the development of a non-invasive prenatal test that may be used to aid in detection of fetal aneuploidy.
- Trial name
- NCT01451684
- Where
- United States
- Volunteers
- 15,000 people
- Sponsor
- Cindy Cisneros
Medical; Abortion, Fetus
Mifepristone and Misoprostol for 2nd Trimester Termination of Pregnancy in Burkina Faso
The goal of this study is to examine the effectiveness and feasibility of a mifepristone-misoprostol medical abortion regimen in terminating pregnancies 13-22 weeks in Burkina Faso.
- Trial name
- NCT03269279
- Testing
- Mifepristone, Misoprostol
- Where
- 4 sites in Burkina Faso
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Fetal Growth Retardation
Non-invasive Placental Chromosome Exploration of Intrauterine Growth Restriction
The objective of this project is the non-invasive prenatal detection of placenta-limited aneuploidies, in patients whose fetuses have a intrauterine growth restriction below 3rd percentile, in parallel with an amniocentesis.
- Trial name
- DPNI-RCIU (NCT05023161)
- Testing
- Blood samples
- Where
- 3 sites in France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bordeaux
Acute Blood Loss Anemia, Postoperative Pain
Effect of Non-Dissection of the Inferior Rectus Sheath on Intraoperative Blood Loss
The purpose of this study is to evaluate the effect of non-dissecting the inferior rectus sheath during primary cesarean delivery on post-operative hemoglobin and post-operative pain control as measured by VAS score and opioid…
- Conditions
- Acute Blood Loss Anemia, Postoperative Pain, Pregnancy
- Trial name
- NCT02762773
- Testing
- non-dissection of inferior rectus sheath, control
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Induction of Labor Affected Fetus / Newborn
An RCT of a Synthetic Osmotic Cervical Dilator for Induction of Labour in Comparison to Dinoprostone Vaginal insErt
Induction of labour (where labour is started artificially) is traditionally carried out with a range of different drugs or by surgery (rupturing the membranes or 'waters').
- Trial name
- SOLVE (NCT03001661)
- Testing
- Dilapan-S, Dinoprostone
- Where
- United Kingdom
- Volunteers
- 674 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Nulliparity, Induction of Labor Affected Fetus / Newborn
"Sweet Expectation and Positive Thinking" the Use of the Mandala in the Induction of Labor
The goal of this clinical trial is to evaluate the efficacy of an artistic tool, the mandala, in a population of pregnant women (nulliparous) undergoing labor induction.
- Trial name
- Mandala (NCT06122168)
- Testing
- Mandala, Standard care
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Bianca Masturzo
Intrapartum Fetal Distress, Neonatal Asphyxia
Oral Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource Settings
The goal of this feasibility pilot clinical trial is to determine if sildenafil citrate 50mg orally, up to three times during labor, can: 1) reduce perinatal mortality and/or bag and mask ventilation at birth in planned vaginal…
- Conditions
- Intrapartum Fetal Distress, Neonatal Asphyxia, Intrapartum Asphyxia, Instrumental Delivery; Affecting Fetus
- Trial name
- NCT06522854
- Testing
- Sildenafil 50 mg Oral Tablet
- Where
- 4 sites in Nigeria
- Sponsor
- University of Alabama at Birmingham
Umbilical Cord; Complications, Affecting Fetus
Perinatal Outcomes in Umbilical Cord Entanglement
Umbilical Cord Entanglement and Perinatal Outcomes.
- Trial name
- AssiutU (NCT03504969)
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Assiut University
Medical Abortion, Fetus
Reducing the Need for In-Clinic Follow-Up for Medical Abortion in Moldova and Uzbekistan
The purpose of this study is to determine whether an alternative method of follow-up after medical abortion is acceptable and feasible for use in Moldova and Uzbekistan.
- Trial name
- NCT01410266
- Testing
- Alternative follow-up
- Where
- 7 sites in Moldova, Uzbekistan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Morbid Obesity, Cesarean Delivery Affecting Fetus
Effect of CPAP on Fetal pH at Scheduled C-section in Morbidly Obese Women
The objective of our study is to evaluate the effect of CPAP on umbilical cord acid base status in morbidly obese women at the time of scheduled cesarean delivery.
- Trial name
- NCT04993651
- Testing
- CPAP
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Eastern Virginia Medical School
Gynecological; Surgery (Previous), Affecting Fetus or Newborn, Due to Obstructed Labor, Analgesia
Postoperative Analgesic Effect of Esketamine
The aim of this study was to determine whether the addition of esketamine to morphine would improve postoperative analgesia after caesarean section.
- Trial name
- NCT05582135
- Testing
- 2 mg morphine sulfate, 0.25mg/kg esketamine, 0.25mg/kg of esketamine in combination with 2 mg morphine sulfate
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Xuanhan County People's Hospital
Surgery; Maternal, Uterus or Pelvic Organs, Affecting Fetus
Turkish Version of Pelvi-Perineal Surgery Sexuality Questionnaire
This prospective, multicentre observational study translates the 13-item Pelvi-Perineal Surgery Sexuality Questionnaire (PPSSQ) from French to Turkish, culturally adapts it, and evaluates its reliability, validity and…
- Trial name
- NCT07090213
- Testing
- Survey using a questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people
- Sponsor
- Bezmialem Vakif University
Labor; Forced or Induced, Affecting Fetus or Newborn
Is More Than One Dose of Misoprostol Needed to Expedite Vaginal Delivery in a Patient With an Unripe Cervix?
The goal of this study is to determine whether inducing labor with just one dose of misoprostol, followed by treatment with oxytocin, will still be effective enough to increase the chances of having a successful vaginal delivery…
- Trial name
- NCT02680314
- Testing
- Misoprostol
- Volunteers
- 243 people
- Sponsor
- Montefiore Medical Center
Labor Pain, Analgesia
Effect of Different Labour Analgesics on Maternal and Fetal Blood Flow Observed by Doppler Ultrasonography
Background: The purpose of this study was to see how intrathecal injections of sufentanil, ropivacaine, and sufentanil added to ropivacaine affected blood flow in the uterine artery, umbilical artery, and middle cerebral artery…
- Conditions
- Labor Pain, Analgesia, Fetus Disorder
- Trial name
- NCT06099938
- Testing
- sufentanil, ropivacaine
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Jinan University
Respiratory Distress Syndrome, Prematurity of Fetus
Intranasal Midazolam Versus Intranasal Ketamine to Sedate Newborns for Intubation in Delivery Room
Anesthesia is rarely used to intubate newborns in delivery room because of the very difficulty of accessing veins. The investigators hypothesized that intranasal administration of sedative would be an effective alternative.
- Trial name
- NCT01517828
- Testing
- Sedation by ketamine, Sedation with Midazolam
- Where
- 3 sites in France
- Volunteers
- 62 people
- Sponsor
- University Hospital, Montpellier
Fetus or Newborn Affected by Condition of Umbilical Cord
Treatment of Granuloma Umbilical in Newborn Babies
The investigators want to show that steroid creme and even better alcohol swaps are just as effective or equal to the current treatment with silver nitrate of granuloma umbilical in newborns.
- Trial name
- NCT01567215
- Testing
- silver nitrate, Steroids, alcohol
- Where
- 2 sites in Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pernille Pedersen
Maternal Anemia in Pregnancy, Before Birth, Maternal; Malnutrition, Affecting Fetus
Maternal Under-nutrition and Effect of Amaranth Grain Flat-bread on Anemia
Introduction: In Ethiopia, maternal malnutrition is a severe public health issue. Underweight and anaemia are the two most common nutritional problems in pregnant women, and they often coexist.
- Trial name
- NCT06536153
- Testing
- Amaranth grain flat bread
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Hawassa University
Labour;Obstructed, Progression
Intrapartum Translabial Ultrasonography Reliability
In a present study vaginal examination of the fetal head station is compared with transperineal ultrasonography evaluation of fetal head station and the ability of ultrasonography evaluation in predicting the time and mode of…
- Conditions
- Labour;Obstructed, Progression, Delivery Problem for Fetus, Ultrasound Therapy; Complications
- Trial name
- ITUSR (NCT04844437)
- Testing
- Transperineal ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Cesarean Section
Comparison of Surgical Conditions in Cesarean Section Under General Anesthesia With Deep Neuromuscular Blockade Versus Succinylcholine
Cesarean delivery under general anesthesia is one of few only surgical procedures, where the most important factor of safety is the speed of the surgery, as a newborn adaptation strongly depends on a time between induction to the…
- Trial name
- NCT01941628
- Testing
- Rocuronium, Succinylcholine
- Where
- Czechia
- Volunteers
- 91 people
- Sponsor
- Charles University, Czech Republic