Clinical trials: Fever in Neutropenia
Febrile Neutropenia
Short Antibiotic Treatment in High Risk Febrile Neutropenia
Infections are a common complication in patients with cancer. They are a significant cause of complications and death in this population.
- Trial name
- NCT05786495
- Testing
- Early Discontinuation of Antibiotics, Standard of Care
- Where
- 4 sites in Canada
- Volunteers
- 80 people
- Sponsor
- University Health Network, Toronto
Cancer, Pediatrics
SPOG 2015 FN Definition. A Multi-center Non-inferiority Trial on Safety of a High Versus Low Temperature Limit Defining Fever in Pediatric Patients With Cancer at Risk for Fever in Chemotherapy-induced Neutropenia
In a multi-center open-label cluster-randomized controlled parallel-group multiple crossover non-inferiority trial in children and adolescents up to 20 years diagnosed with cancer requiring chemotherapy, primarily the safety, and…
- Conditions
- Cancer, Pediatrics, Fever, Neutropenia
- Trial name
- NCT02324231
- Testing
- 39.0°C temperature limit defining fever, 38.5°C temperature limit defining fever
- Where
- 6 sites in Switzerland
- Volunteers
- 269 people
- Sponsor
- Swiss Pediatric Oncology Group
Chemotherapy, Neutropenia
Garlic in Patients With Febrile Neutropenia
To determine the clinical effects of garlic in preventing and treatment of patients with chemotherapy related febrile neutropenia.These patients have a very high incidence of infections which are not routinely covered by the…
- Trial name
- NCT00247039
- Testing
- Solgar Israel
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Hadassah Medical Organization
Neutropenia, Febrile
A Post Marketing Surveillance Study of Lipo-AB® (Amphotericin B) in Neutropenic Patients With Persistent Fever
Amphotericin B is a polyene antifungal drug used for the treatment of many systemic fungal infections. It is associated with many side effects which in some cases can be very severe and potentially lethal.
- Trial name
- NCT03511820
- Testing
- Lipo-AB® (amphotericin B) liposome
- Where
- 9 sites in Taiwan
- Volunteers
- 54 people
- Sponsor
- TTY Biopharm
Febrile Neutropenia, Acute Leukemia
iDTECT Blood Performance for the Identification of Viral or Bacterial Pathogens in Febrile Neutropenic Patients
Prospective, multicentre French observational study assessing the performance and medico-economic utility of iDTECT Blood versus conventional microbiologic diagnosis in patients with febrile neutropenia
- Conditions
- Febrile Neutropenia, Acute Leukemia, Stem Cell Transplantation, Infection
- Trial name
- IDENTIFY (NCT03364257)
- Testing
- iDTECT Blood
- Where
- 5 sites in France
- Volunteers
- 97 people
- Sponsor
- Pathoquest
Febrile Neutropenia
Plasma Host-Microbe Proteomics to Predict Complications in High-risk Febrile Neutropenia
Febrile neutropenia (FN) is a common oncologic emergency in patients with hematologic malignancies, associated with high morbidity and mortality.
- Trial name
- NCT07277387
- Testing
- Plasma and DNA sample collection for proteomic and genomic analysis
- Where
- 3 sites in Spain
- Volunteers
- 350 people
- Sponsor
- Instituto de Investigación Biomédica de Salamanca
Fever
Fever Management in Children With Febrile Neutropenia
The aim of this study is to determine the effect of the cold steam application on body temperature in combination with the treatment algorithm in fever management in children with febrile neutropenia.
- Trial name
- NCT05189236
- Testing
- Control Group (Only Algorithm of Febrile Neutropenia Management), Experimental Group (Algorithm of Febrile Neutropenia Management+Cold Steam)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Acibadem University
Neutropenia, Cancer
Once-Daily Amikacin Plus Cloxacillin in Febrile Neutropenic Children
Once-daily dose administration of aminoglycoside in adults is effective and economical. However, its value in febrile neutropenic children, especially in Thailand, is less well researched.
- Conditions
- Neutropenia, Cancer, Fever
- Trial name
- NCT00129688
- Testing
- cloxacillin and amikacin (once or twice daily dosage)
- Volunteers
- 166 people
- Sponsor
- Khon Kaen University
Breast Cancer, Fever
Same Day Dosing of Pegfilgrastim in Breast Cancer Patients Undergoing Chemotherapy (TAC)
The purpose of this study is to provide data on the safety and efficacy of pegfilgrastim when administered on the same day versus the next day of chemotherapy, as measured by the duration of grade 4 neutropenia.
- Conditions
- Breast Cancer, Fever, Neutropenia
- Trial name
- NCT00115414
- Testing
- pegfilgrastim, docetaxel, doxorubicin
- Sponsor
- Amgen
Febrile Neutropenia
New Diagnostics in Neutropenia
Mortality due to bloodstream infections in patients with neutropenia and haematological malignancies is high and optimal management is hampered by long turnaround times of conventional blood cultures.
- Trial name
- NCT05174546
- Testing
- T2 magnetic resonance
- Where
- Australia
- Volunteers
- 100 people
- Sponsor
- The University of Queensland
Septic Shock
Pentaglobin in CRE and PA Neutropenic Infections
To demonstrate that the early addition of Pentaglobin to the best available antimicrobial therapy is able to reduce mortality and improve survival in neutropenic febrile acute leukemia or allo- Hematopoietic stem cell…
- Trial name
- PENTALLO (NCT03494959)
- Testing
- Pentaglobin
- Where
- 20 sites in Italy
- Volunteers
- 120 people
- Sponsor
- Gruppo Italiano Trapianto di Midollo Osseo