Clinical trials: Fibroblast
Bladder Transitional Cell Carcinoma, Bladder Cancer
Phase I BLASST-3 Trial
The aim of this research is to see whether using a drug that blocks a protein called FGFR (fibroblast growth factor receptor) prior to surgery is safe and effective in patients with bladder cancer that have mutations in FGFR3 or…
- Conditions
- Bladder Transitional Cell Carcinoma, Bladder Cancer, Fibroblast Growth Factor Receptor
- Trial name
- (BLASST)-3 (NCT04972253)
- Testing
- Infigratinib
- Sponsor
- Guru P. Sonpavde
Breast Neoplasms, Positron Emission Tomography
Comparison of [68Ga]GaFAPI-46 PET/CT and [18F]FDG PET/CT Findings in Breast Carcinoma
The aim of this study is to compare the diagnostic performance of 68Ga-FAPI-46 PET/CT and 18F-FDG PET/CT in primary and metastatic lesions of breast cancer and to reveal the best diagnostic imaging time of 68Ga-FAPI-46 PET/CT.
- Conditions
- Breast Neoplasms, Positron Emission Tomography, Fibroblast Activation Protein Inhibitor, Fluorodeoxyglucose F18
- Trial name
- NCT05339113
- Testing
- 68Ga-FAPI-46 PET/CT
- Where
- Azerbaijan
- Volunteers
- 100 people
- Sponsor
- The National Center of Oncology, Azerbaijan
Cancer, Skin Fibroblasts
Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome
Background: Nicotinamide riboside (NR) is a vitamin B3 dietary supplement. It may help improve muscle function, that may in turn may improve a person s exercise capacity.
- Conditions
- Cancer, Skin Fibroblasts, Muscle Weakness
- Trial name
- NCT03789175
- Testing
- Nicotinamide Riboside (NR)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Fibroblast Growth Factors, Wound Healing
Clinical Study of Kangfuxin and Basic Fibroblast Growth Factor in Promoting the Healing of Donor Site
The main objective of this study is to observe whether basic fibroblast growth factor and Kangfuxin Liquid can promote the wound healing in the donor area and further evaluate the healing quality.
- Trial name
- NCT04234321
- Testing
- basic fibroblast growth factor, Kangfuxin Liquid, 0.9% Normal saline
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Kidney Disease Requiring Chronic Dialysis, Hyperphosphatemia
Low-Phosphate Diet and Fibroblast Growth Factor-23 Level
The aims of the study are to evaluate the effect of low-phosphate diet on FGF23 level and to determine the optimal amount of dietary phosphate restriction in hemodialysis patients.
- Conditions
- Chronic Kidney Disease Requiring Chronic Dialysis, Hyperphosphatemia, Dietary Intervention, Elevated Fibroblast Growth Factor-23
- Trial name
- NCT03367338
- Testing
- Low-phosphate diet
- Where
- Taiwan
- Volunteers
- 35 people
- Sponsor
- Wan-Chuan Tsai
Anemia of Chronic Kidney Disease, Endothelial Dysfunction
Anemia Correction and Fibroblast Growth Factor 23 Levels in Chronic Kidney Disease , and Renal Transplant Patient
The fibroblast growth factor-23-bone-kidney axis is part of newly discovered biological systems linking bone to other organ functions through a complex endocrine network that is integrated with the parathormone/vitamin D axis and…
- Conditions
- Anemia of Chronic Kidney Disease, Endothelial Dysfunction, Left Ventricular Hypertrophy, Fibroblast Growth Factor 23
- Trial name
- NCT03193073
- Testing
- detailed echocardiography, serum fibroblast growth factor-23, flow mediated dilatation of forearm
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Omnia Mohammed Hashem
Fibroblasts
Use of Biopsy Punch for Skin Biopsies for Fibroblasts Culturing
Fibroblasts can be cultured from human skin biopsies using fetal bovine serum and artificial growth medium. Fibroblasts cultured in this way retain the genetic characteristics of their donor but can be used for experiments where…
- Trial name
- NCT00340912
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Fibroblast
Fibroblast Growth Factor-23 (FGF-23) is Independently Associated With Left Ventricular Mass Index (LVMI) and Myocardial Performance Index (MPI) in Haemodialysis Patients
Serum FGF-23 levels will be measured in patients with a history of coronary artery disease and aortic valve calcifications.It will be searched whether patients with MPI>0.47 had higher or lower serum FGF-23 levels than those with…
- Trial name
- NCT01154842
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Diskapi Teaching and Research Hospital