Clinical trials: Fibroids, Uterine
Uterine Leiomyoma
Uterine Artery Embolization With Microspheres in Patients With Leiomyoma.
To evaluate the therapeutic response to uterine artery embolization in 30 patients with leiomyoma using the microspheres Embosoft (Embosoft® - Scitech Medical).
- Trial name
- EMBOSOFT I (NCT03535610)
- Testing
- Uterine Embolization
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Scitech Produtos Medicos SA
Uterine Fibroids, Arterial Embolization
Uterine Fibroid Embolization- Long Term Follow up and Technical Perspectives
The purpose of this prospective non-randomised study is to examine whether two different microspheres (Bead-Block and Embosphere) are equally effective in the treatment of the uterine fibroid controlled with contrast-enhanced MR…
- Trial name
- NCT01852734
- Testing
- embolizations ,uterine fibroid, embolizations
- Where
- 2 sites in Denmark
- Volunteers
- 52 people
- Sponsor
- Odense University Hospital
Uterine Fibroids, Menorrhagia, Endometriosis
Study Comparing Conventional vs. Robotic-assisted Laparoscopic Hysterectomy
The purpose of this study is to compare two ways of performing laparoscopic hysterectomy - robotic-assisted vs. conventional laparoscopy.
- Trial name
- NCT00485355
- Testing
- conventional laparoscopic hysterectomy, robotic assisted laparoscopic hysterectomy
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Uterine Fibroid, Myoma;Uterus
INTERVENTION WITH TRANEXAMIC ACID TO REDUCE HAEMORRHAGE DURING LAPAROSCOPIC MYOMECTOMY
This research is planned as a randomised double-blind controlled trial. interventions to reduce haemorrhage during laparoscopic myomectomy for fiboids is important.
- Conditions
- Uterine Fibroid, Myoma;Uterus, Tranexamic Acid Adverse Reaction
- Trial name
- NCT04192643
- Testing
- Tranexamic Acid 100 MG/ML
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alkü Alanya Education and Research Hospital
Uterine Bleeding, Uterine Leiomyomas
Ultrasound Transformation of Myomas During Relugolix-Estradiol-Norethisterone Treatment: The MySaturn Study
Uterine fibroids are benign tumors originating from the uterine muscle, affecting up to 70% of women by their 50s. Risk factors include African descent, nulliparity, obesity, and diabetes.
- Conditions
- Uterine Bleeding, Uterine Leiomyomas, Uterine Hemorrhage, Uterine Neoplasms
- Trial name
- MySaturn (NCT06953076)
- Testing
- Relugolix/estradiol/norethisterone acetate
- Where
- Italy
- Volunteers
- 111 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Infertility, Female, Fibroid Uterus
Impact of Esmya on Fertility to Infertile Women With Fibroids Managed With Assisted Reproduction Techniques
Fibroid is a frequent pathology of infertile women. Its deleterious effect on the infertility would be due to the mechanical way. The interest of the resection of intramural fibroids is discussed.
- Trial name
- NACRE (NCT03349190)
- Testing
- ULIPRISTAL ACETATE
- Where
- 23 sites in France, New Caledonia
- Volunteers
- 127 people
- Sponsor
- ASSOCIATION POUR LE DEVELOPPEMENT EN FECONDATION IN VITRO
Cancer Debulking, Enlarged Uterus
Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy
To determine if opioid consumption postoperatively among patients undergoing non-emergent laparotomy by the gynecologic oncology service who receive intrathecal morphine with intraoperative lidocaine (IML) infusion are lower than…
- Conditions
- Cancer Debulking, Enlarged Uterus, Fibroid Uterus, Adnexal Mass
- Trial name
- NCT05017246
- Testing
- Bupivacaine, Morphine, Lidocaine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Washington University School of Medicine
Uterine Artery Embolization for Uterine Leiomyomata
Patient-Controlled Epidural Analgesia After Uterine Artery Embolization
Uterine artery embolization (UAE) is commonly used to treat symptomatic uterine leiomyomata through induction of infarction and subsequent hyaline degeneration.
- Trial name
- NCT02236585
- Testing
- Patient-controlled epidural analgesia, Continuous epidural analgesia
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Uterine Leiomyomas
Intra-arterial Lidocaine for Pain Control Post Uterine Fibroid Embolization
Uterine artery embolization (UAE) is a minimally invasive treatment for women with symptomatic fibroids. It is similar to hysterectomy in term of satisfaction and symptoms improvement, with fewer complications and at lower cost.
- Trial name
- NCT02293447
- Testing
- Lidocaine per-embolization, Lidocaine post-embolization
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University Health Network, Toronto
Fibroid Uterus, Fibroid Tumor
Effects of Simvastatin on Uterine Leiomyoma Size
The study aims to study the effect of simvastatin on the size of uterine fibroids.
- Conditions
- Fibroid Uterus, Fibroid Tumor, Leiomyoma, Fibromyoma
- Trial name
- NCT03400826
- Testing
- Simvastatin 40mg
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Ovarian Cancer, Fibroids
Pilot Study of Liposomal Bupivacaine Redosing in Patients Undergoing Major Gynecologic Procedures
The purpose of this research study is to find out which type of transversus abdomens plane (TAP) and block (bupivacaine, liposomal bupivacaine or liposomal bupivacaine with re-dosing at 48-60 hours) improves your pain control and…
- Conditions
- Ovarian Cancer, Fibroids, Uterine Cancer
- Trial name
- NCT04849858
- Testing
- Bupivacaine, Liposomal bupivacaine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of California, Irvine
Uterine Fibroids
Magnetic Resonance Elastography (MRE) of Uterine Fibroids
The purpose of this study is to gain additional information regarding use of Magnetic Resonance Elastography (MRE) for uterine fibroid characterization.
- Trial name
- MRE (NCT01229826)
- Testing
- MR Elastography
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Fibroids, Uterine
Patient Centered Results for Uterine Fibroids
The overall goal of this project is to better enable patients with uterine fibroids (UF) to make informed decisions about treatment options by leveraging the highest possible evidence of healthcare quality.
- Trial name
- COMPARE-UF (NCT02260752)
- Testing
- hysterectomy, Uterine arterial embolization, myomectomy
- Where
- 9 sites in United States
- Volunteers
- 3,094 people
- Sponsor
- Duke University
Heavy Menstrual Bleeding, Uterine Fibroid
LIBERTY EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids
The purpose of this study was to determine the long-term efficacy and safety of relugolix 40 milligrams (mg) once daily co-administered with estradiol (E2) and norethindrone acetate (NETA) for 28 weeks on heavy menstrual bleeding…
- Trial name
- NCT03412890
- Testing
- Relugolix, Estradiol/norethindrone acetate
- Where
- 150 sites in United States, Belgium and 7 more
- Volunteers
- 477 people
- Sponsor
- Myovant Sciences GmbH
Uterine Bleeding, Uterine Fibroids
What Are we Missing? Diagnosing Uterine Adenomyosis Using Ultrasound Elastography
To improve the clinical care of women with pelvic pain and abnormal uterine bleeding due to benign uterine conditions including leiomyomas (uterine fibroids) and adenomyosis by evaluating the accuracy of radiology diagnostic…
- Conditions
- Uterine Bleeding, Uterine Fibroids, Adenomyosis
- Trial name
- NCT01992718
- Testing
- Evaluation of MRI, US for pelvic and uterine conditions, Patient preference between MRI and Ultrasound
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of Michigan
Endometrial Cancer, Abnormal Uterine Bleeding
ONSD as an ICP Marker in vNOTES and TLH
Patients undergoing conventional total laparoscopic hysterectomy (TLH) are typically placed in the Trendelenburg position with intraabdominal carbon dioxide (CO₂) insufflation.
- Conditions
- Endometrial Cancer, Abnormal Uterine Bleeding, Myoma;Uterus
- Trial name
- NCT07250178
- Testing
- vNOTES, TLH
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Intrauterine Adhesion
Intrauterine Balloon Dilatation Therapy in the Prevention of Adhesion Formation After Hysteroscopic Myomectomy
Transcervical resection of submucous myomas (TCRM) is nowadays considered necessary if it is associated with infertility or miscarriage or menorrhagia.
- Trial name
- NCT03169478
- Testing
- multiple myoma IUB dilatation group
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Fu Xing Hospital, Capital Medical University
Myoma;Uterus
Laparoscopic Myomectomy With Morcellation or Transvaginal Extraction of Surgical Specimens.
Laparoscopic myomectomy represents the fertility-sparing gold standard approach for the management of subserosal and intramural uterine myomas: this technique allows faster recovery, less complications and improved surgical…
- Trial name
- MYMOTE-1 (NCT03570879)
- Testing
- Power morcellation, Transvaginal extraction
- Volunteers
- 250 people
- Sponsor
- Università degli Studi dell'Insubria
Leiomyoma, Menorrhagia
Treatment of Uterine Fibroids With Asoprisnil(J867)
The objective of this study is to determine the safety and effectiveness of asoprisnil in symptomatic women with abnormal uterine bleeding associated with uterine fibroids.
- Conditions
- Leiomyoma, Menorrhagia, Metrorrhagia
- Trial name
- NCT00152269
- Testing
- Asoprisnil
- Volunteers
- 475 people
- Sponsor
- Abbott
Leiomyoma
Study of Tumor-shrinking Decoction (TSD) to Treat Symptomatic Uterine Fibroids
On the basis of empirical evidence and clinical practice, the investigators have developed a formula called Tumor-shrinking Decoction (TSD) used in the treatment of uterine fibroids (UFs).
- Trial name
- NCT02189083
- Testing
- TSD
- Where
- China
- Volunteers
- 78 people
- Sponsor
- The University of Hong Kong