Clinical trials: Fibromyalgia (FM)
Fibromyalgia
A Phase 3 Study To Evaluate The Efficacy And Safety Of TNX-102 SL In Patients With Fibromyalgia
This is a Phase 3, randomized, parallel-group, double-blind, placebo-controlled, 14-week study designed to evaluate the efficacy and safety of TNX-102 SL 5.6 mg (2 x 2.8 mg tablets) taken daily at bedtime for the treatment of…
- Trial name
- RALLY (NCT04508621)
- Testing
- TNX-102 SL
- Where
- 36 sites in United States
- Volunteers
- 514 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Fibromyalgia
Efficacy of NAT-FM Treatment for Fibromyalgia
The main objective of this study is to analyse the efficacy of the NAT-FM multicomponent treatment program as coadjuvant of treatment-as-usual (TAU) compared to TAU alone.
- Trial name
- NAT-FM (NCT04190771)
- Testing
- TAU + multicomponent treatment NAT-FM, Treatment as Usual (TAU)
- Where
- Spain
- Volunteers
- 169 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Fibromyalgia
Living With Fibromyalgia: Triggers,Subgroups, and a Cognitive-Behavioral and Interactive Technology-Based Intervention
The purpose of this study is to conduct semi-structured qualitative interviews to examine the personal experiences of women living with fibromyalgia.
- Trial name
- NCT00222690
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Fibromyalgia
Phase 2 Study of TD-9855 to Treat Fibromyalgia
The purpose of this study study is to determine whether TD-9855 is effective in treating patients with fibromyalgia.
- Trial name
- NCT01693692
- Testing
- TD-9855 Group 1, TD-9855 Group 2
- Where
- 34 sites in United States
- Volunteers
- 392 people
- Sponsor
- Theravance Biopharma
Fibromyalgia (FM), Chronic Fatigue Syndrome (CFS)
Functional and Affective Effects of a Brief tDCS Intervention in Fibromyalgia and Chronic Fatigue Syndrome
Functional and Affective Effects of a brief tDCS Intervention in Fibromyalgia and Chronic Fatigue Syndrome Fibromyalgia (FM) and chronic fatigue syndrome (CFS) are characterized by persistent, multidimensional symptoms arising…
- Trial name
- FibFatDCS (NCT07573709)
- Testing
- Transcraneal Direct Current Electric Stimulation (tDCS), Transcranial Direct Current Electric Stimulation (tDCS)
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Donostia
Fibromyalgia (FM), Chronic Low Back Pain (CLBP)
Pain Neuroscience Education for Chronic Pain
Chronic pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, with a high prevalence in Spain (25.9%) and an average duration of 6.83 years, highlighting its significant health…
- Conditions
- Fibromyalgia (FM), Chronic Low Back Pain (CLBP), Chronic Pain
- Trial name
- PNE (NCT07693998)
- Testing
- Therapeutic Exercise and Education in Pain Neuroscience
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- University of Valencia
Fibromyalgia (FM)
Between Paws and Affections - Impact of Dog-Assisted Therapy in Fibromyalgia Patients
The purpose of this study is to evaluate the effectiveness and medium-term maintenance of a structured dog-assisted therapy (DAT) protocol, "Entre Patas e Afetos" (Between Paws and Affections), in reducing pain, anxiety and…
- Trial name
- IDAT26 (NCT07356206)
- Testing
- Behavioral: Dog Assisted Therapy (DAT - "Between Paws and Affections"), Behavioral: Psychoeducation and Relaxation without Dogs (Control)
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- University of Minho
Fibromyalgia (FM), Subclinical Ventricular Dysfunction
Evaluation of Myocardial Function by Global Longitudinal Strain (GLS) Measurement in 2D Echocardiography of Patients With Fibromyalgia
Fibromyalgia (FM) is a chronic pain syndrome that affects multiple body systems and is often associated with fatigue, sleep disturbances, anxiety, and other comorbidities.
- Conditions
- Fibromyalgia (FM), Subclinical Ventricular Dysfunction, Myocardial Function
- Trial name
- GLS in FM (NCT07150455)
- Testing
- Echocardiographic Assessment (2D Speckle Tracking)
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Fibromyalgia
"REACT-FM-EXT": Real-World Evidence From Smartphone-Based Acceptance and Commitment Therapy in Fibromyalgia: An Extension Study
This is an extension study of REACT-FM. The primary objective of the study is to assess the response to digital therapy in the treatment of fibromyalgia over an additional 9 months.
- Trial name
- NCT05149222
- Testing
- Digital ACT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Swing Therapeutics, Inc.
Fibromyalgia (FM)
Effect of Bei App for Fibromyalgia
Background: Fibromyalgia (FM) is a complex, chronic condition characterized by widespread musculoskeletal pain, cognitive dysfunction, fatigue, and emotional comorbidities such as anxiety and depression.
- Trial name
- NCT07090434
- Testing
- Mobile App + psychoeducation program, Psychoeducation program
- Volunteers
- 70 people
- Sponsor
- Universidad Autonoma de Madrid
ME/CFS, Fibromyalgia (FM)
Whole-body Cryotherapy in Those With Chronic Fatigue: A Feasibility Study
Chronic fatiguing illnesses such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), Fibromyalgia, and Long COVID are becoming a major global health challenge.
- Conditions
- ME/CFS, Fibromyalgia (FM), Long-COVID, Control Group
- Trial name
- NCT07874217
- Testing
- Cryotherapy
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Chronic Low Back Pain (CLBP), Acute Low Back Pain
Multimodal Imaging and Biospecimen Collection for Low Back Pain (LBPB)
This prospective cohort study investigates the neurobiological, genetic, and psychosocial mechanisms underlying acute and chronic low back pain (LBP).
- Conditions
- Chronic Low Back Pain (CLBP), Acute Low Back Pain, Low Back Pain, Chronic Pain
- Trial name
- LBPB (NCT06967363)
- Testing
- Nerve Block, endoscopic spinal disecetomy, Medication
- Where
- 2 sites in China
- Volunteers
- 360 people
- Sponsor
- Peking University Third Hospital
Fibromyalgia (FM), Work Ability
Assessment of the Functional Capacity of Patients with Fibromyalgia: Clinical Validity
Fibromyalgia is one of the main causes of chronic pain without a specific etiology, affecting 8% of the Spanish population, especially women.
- Conditions
- Fibromyalgia (FM), Work Ability, Physical Activity, Physical Functioning
- Trial name
- NCT06819930
- Testing
- Physical Assessments, Questionnaires, and Accelerometry for Fibromyalgia evaluation
- Where
- 2 sites in Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Ramon Llull
Postural Orthostatic Tachycardia Syndrome (POTS), Fibromyalgia (FM)
Auto-immune Contribution in Symptom-based Sensory and Autonomic Disorders
Postural Orthostatic Tachycardia Syndrome (PoTS) is a condition where the heart rate increases when standing up, causing symptoms like dizziness and fainting.
- Trial name
- ACSSAD (NCT06992531)
- Testing
- Questionnaire and Physical Exam, Nerve conduction studies, Microneurography
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- King's College London
Fibromyalgia (FM)
Multicomponent FIBROWALK Therapy Plus Unified Protocol for Emotional Regulation in Individuals With Fibromyalgia
Fibromyalgia is a chronic condition characterized by widespread pain, fatigue, sleep disturbances, and cognitive dysfunction. Although the FIBROWALK multicomponent program improves physical functionality and pain, its impact on…
- Trial name
- FIBROWALK+UP (NCT06906991)
- Testing
- FIBROWALK, Unified Protocol
- Where
- Spain
- Volunteers
- 182 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Studying Efficacy of dTMS in FM
dTMS as a Treatment for Patients With Fibromyalgia
Purpose: The purpose of the study is to explore the efficacy of H1 deep TMS for the treatment of FMS. Design: Prospective randomized sham controlled trial Study Population \& sample size:forty (40) FMS subjects between 18-80…
- Trial name
- NCT03460340
- Testing
- prefrontal deep rTMS of H1 Coil
- Volunteers
- 40 people
- Sponsor
- Shalvata Mental Health Center
Fibromyalgia
Prospective Study to Evaluate a Digital Regimen for Fibromyalgia Management
PROSPER-FM is a multi-center, randomized, non-significant risk device study to evaluate the safety and efficacy of two digital therapy smartphone applications in participants with fibromyalgia.
- Trial name
- PROSPER-FM (NCT05243511)
- Testing
- Digital ACT, Digital Symptom Tracker
- Where
- 25 sites in United States
- Volunteers
- 275 people
- Sponsor
- Swing Therapeutics, Inc.
Fibromyalgia, Fibromyalgia (FM)
Feasibility and Preliminary Effects of an Asynchronous Microlearning Intervention on Fibromyalgia Knowledge Among Primary Health Care Workers
This randomized controlled pilot trial will evaluate the feasibility and preliminary effects of an asynchronous microlearning intervention on fibromyalgia knowledge among Primary Health Care workers.
- Conditions
- Fibromyalgia, Fibromyalgia (FM), Fibromyalgia Syndrome
- Trial name
- FIBROK-PILOT (NCT07865767)
- Testing
- Written Educational Material on Fibromyalgia, Asynchronous Microlearning Intervention on Fibromyalgia
- Where
- Chile
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Instituto Neurociencia Del Dolor
Fibromyalgia (FM)
Exercise and Neuromodulation in Fibromyalgia
Exercise is recommended for people with fibromyalgia because it can reduce symptoms and improve quality of life. Some studies show that high-intensity exercises like running or cycling (also called high-intensity interval…
- Trial name
- NCT07323199
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Neuromodulators
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Universidad Nacional Andres Bello
Fibromyalgia (FM), Chronic Pain
The Effect of Physiotherapy Integrated With Yoga and Mindfulness on Individuals With Fibromyalgia
The current study investigates the effect of an integrative physiotherapy and mind-body program called PhYoMind intervention on disability and symptoms in individuals with fibromyalgia (FM).
- Trial name
- PhYoMind (NCT07145788)
- Testing
- PhYoMind, Exercise
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University Hospital Tuebingen