Clinical trials: Fibrositis
Fibromyalgia, Chronic Pain
Functional Neuroimaging in Fibromyalgia Patients Receiving tDCS
The purpose of this study is to evaluate effectiveness and cerebral neuronal ability to adaptation in patients with fibromyalgia who receive pregabalin and transcranial direct current stimulation.
- Trial name
- NCT01904097
- Testing
- Pregabalin, Transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Fibromyalgia
NK-ORB Expression of Mu Receptor on Lymphocytes in Rehabilitation
Chronic pain is a serious disorder that causes physical suffering and emotional distress. NK cells are cytotoxic granular cells playing a crucial role in innate immunity.
- Trial name
- NK-ORB (NCT06458569)
- Testing
- Rehabilitation
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Raffaele Roma
Fibromyalgia
The Altered Immune Response to Exercise in Patients With Fibromyalgia Before and After a Mind-body Intervention
The purpose of this study is to compare two different exercise programs to see if there are differences after exercise in fibromyalgia (FM) symptoms and responses from the immune system.
- Trial name
- NCT03441997
- Testing
- Mind-body exercise, Light mobility exercises
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Fibromyalgia
Psychological Wellbeing, Physical Activity, and Disability in Fibromyalgia
This study aims to investigate the association between psychological wellbeing, physical activity, and disability in patients with fibromyalgia.
- Trial name
- NCT05946356
- Testing
- no intervention - cross-sectional observational only
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ahram Canadian University
Depressive Disorder, Major, Diabetic Neuropathies
Study Evaluating the Potential of DVS SR to Inhibit the CYP2D6 Pathway
To evaluate the effects of multiple oral doses of desvenlafaxine sustained release (DVS SR) and paroxetine on the biotransformation of codeine to morphine in healthy subjects.
- Conditions
- Depressive Disorder, Major, Diabetic Neuropathies, Fibromyalgia, Vasomotor Symptoms
- Trial name
- NCT00456898
- Testing
- desvenlafaxine sustained release (DVS SR), Paroxetine, Codeine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Low Back Pain, Low Back Pain, Recurrent
Structural White and Gray Matter Correlates of Impaired Muscle Control and Deficient Pain Processing
Although the cause of persistent non-specific low back pain (LBP) remains unknown, structural and functional alterations of the brain, alterations in the lumbar muscles and dysfunction of the central nervous system have been…
- Conditions
- Low Back Pain, Low Back Pain, Recurrent, Low Back Pain, Chronic, Healthy Volunteers
- Trial name
- B~Maps (NCT06143319)
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Ghent
Rotator Cuff Tears, Central Sensitisation
Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair
This study aims to investigate the effects of Pregabalin intake on shoulder pain management in patients with central sensitization undergoing arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Central Sensitisation, Neuropathic Pain
- Trial name
- NCT06367998
- Testing
- Pregabalin
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Fibromyalgia
The Validity and Reliability of the Turkish Version of the Combined Index of Severity of Fibromyalgia
The aim of the investigator's study is to determine the validity and reliability of the Turkish version of the Combined Index of Severity (ICAF) in Turkish patients with Fibromyalgia Syndrome (FMS).
- Trial name
- NCT03800199
- Testing
- Perceptive rehabilitation
- Where
- Cyprus
- Volunteers
- 200 people
- Sponsor
- European University of Lefke
Fibromyalgia Syndrome
Add-on Complex Ayurvedic Treatment in Fibromyalgia-Syndrome Compared to Standard Care Alone
The aim of this study is to evaluate the effectiveness of an additive complex āyurvedic diagnosis and treatment compared to conventional standard care alone in stationary patients with Fibromyalgia Syndrome.
- Trial name
- KAFA (NCT01389336)
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Andreas Michalsen
Myofascial Pain Syndrome
Kinesio Taping in Subjects With Myofascial Pain Syndrome: a Randomized Controlled Trial
Musculoskeletal dysfunction is considered as a major public health problem affecting about one third of the adult population. Myofascial pain syndrome (MPS) characterized by myofacial trigger points as well as fascia tenderness…
- Trial name
- NCT02029391
- Testing
- Manual pressure release, Kinesio tape
- Where
- Taiwan
- Volunteers
- 31 people
- Sponsor
- National Taiwan University Hospital
Myofascial Pain Syndrome, Neck Pain
Immediate Stiffness Changes in Myofascial Trigger Points After Dry Needling
Shear-wave elastography (SWE) is considered as a useful tool for quantifying muscle stiffness. Considering that Myofascial Trigger Points (MTrP) are defined as "hyperirritable zones in contracted bands of muscle, thought to be…
- Conditions
- Myofascial Pain Syndrome, Neck Pain, Trigger Point Pain, Myofascial
- Trial name
- ELECTROP (NCT04832074)
- Testing
- Dry Needling
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Camilo Jose Cela University
Fibromyalgia Syndrome
The Effect of Neural Therapy on Heart Rate Recovery, Cardiac Parameters and Pain in Fibromyalgia
Background: Autonomic dysfunction has been observed in patients with fibromyalgia and is associated with symptoms and arrhythmia development in such patients.The investigators can analyze dysautonomia using heart rate recovery…
- Trial name
- NCT06795750
- Testing
- neural therapy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uşak University
Myofascial Pain - Dysfunction Syndrome of TMJ, Trigger Point Pain, Myofascial
Comparison of Therapeutic Effects of Trigger Point Injection and Twin Nerve Block in Chronic Myofascial Pain Patients
To see if there is there any difference in the treatment outcomes/results such as changes in pain intensity in patients with myofascial pain who have been treated with trigger point injections or twin block?
- Conditions
- Myofascial Pain - Dysfunction Syndrome of TMJ, Trigger Point Pain, Myofascial, Nerve Block
- Trial name
- NCT03870191
- Testing
- Injection of either twin block or trigger point injection.
- Volunteers
- 48 people
- Sponsor
- Rutgers University
Fibromyalgia
Nurse Educational Intervention to Improve Symptoms in Fibromyalgia Patients
To improve self-care and therapy adherence by fibromyalgia (FM) patients through a nursing educational intervention. Historic diagnoses of subjects included terms such as "insane", "imaginary ill", "whiny"; as well, their…
- Trial name
- NCT05247411
- Testing
- Educational intervention
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Milano Bicocca
Fibromyalgia
MDMA-assisted Therapy for Fibromyalgia
Fibromyalgia is a debilitating chronic pain disorder. Based on prior research with MDMA, it can be hypothesized MDMA-assisted therapy in fibromyalgia patients may increase the range of positive emotions, interpersonal trust, and…
- Trial name
- NCT06066853
- Testing
- MDMA
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Spaulding Rehabilitation Hospital
Fibromyalgia
Impact of a Specific Training Program on the Neuromodulation of Pain in Fibromyalgia Subjects
Fibromyalgia affects 1.4 now 2.2% of the general population whose symptom is the presence of widespread pain in all four quadrants of the body. Currently, there is no causal treatment of fibromyalgia syndrome.
- Trial name
- DOUFISPORT (NCT02486965)
- Testing
- thermode (TSA-II model), Adapted Physical Activity, Physical activity
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Brest
Chronic Pain
Repetitive Thinking in FibroMyalgia and Attentional Bias
Theoretical models of chronic pain hypothesize a privileged treatment of pain-related information that would be the basis of avoidance behaviors in chronic pain.
- Trial name
- PRFM-BA (NCT03466892)
- Testing
- Questionnaires and computer paradigm
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Primary Fibromyalgia
12-Month Open-Label Long-term Safety Study of TNX-102 SL Tablets in Fibromyalgia Patients
This was an open-label, extension trial designed to evaluate the long-term safety over 12 months of TNX-102 SL tablets taken daily at bedtime for the treatment of fibromyalgia.
- Trial name
- BESTFIT-OLE (NCT02015234)
- Testing
- TNX-102 SL
- Where
- 13 sites in United States
- Volunteers
- 158 people
- Sponsor
- Tonix Pharmaceuticals, Inc.
Fibromyalgia
Neuroimaging Effects of Cognitive Behavioral Therapy in Fibromyalgia
This study design has two components: 1) a cross sectional assessment of brain connectivity and response to pain in healthy controls and demographically matched fibromyalgia patients, and 2) a longitudinal assessment of the same…
- Trial name
- NCT01345344
- Testing
- Cognitive Behavioral Therapy, Disease Education
- Where
- 2 sites in United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Fibromyalgia, Pain
Cyclobenzaprine Extended Release (ER) for Fibromyalgia
Amrix (Cyclobenzaprine hydrochloride Extended release capsules) is approved by the FDA as a muscle relaxant, indicated for the treatment of muscle spasm associated with acute, painful musculoskeletal conditions.
- Conditions
- Fibromyalgia, Pain, Sleep, Fatigue
- Trial name
- NCT01041495
- Testing
- cyclobenzaprine ER (AMRIX)
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- State University of New York - Upstate Medical University
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