Clinical trials: Fine-needle Aspiration
Neoplasms, Infection
A Multi-center, Prospective, Single-blind, Controlled Trial Comparing Diagnostic Value of Different EUS-FNA Techniques
The aim of this study is to compare endoscopic ultrasound guided-fine needle aspiration (EUS-FNA) with a standard 22-gauge needle using "standard suction", "slow-pull" and "wet suction" for thoracic/abdominal solid/solid-cystic…
- Conditions
- Neoplasms, Infection, Inflammation, Lymphoma
- Trial name
- EUS-FNA (NCT03674710)
- Testing
- Standard suction, slow-pull, wet suction, Standard suction, wet suction, slow-pull, Slow-pull, standard suction, wet suction
- Where
- 4 sites in China
- Volunteers
- 300 people
- Sponsor
- Shanghai Zhongshan Hospital
Pancreatic Diseases
The 22G Franseen Needle Combined With Different Aspiration Techniques for Endoscopic Ultrasound-guided Fine-needle Biopsy
The goal of this clinical study is to compare the tissue adequacy, cellularity, blood contamination, accuracy, sensitivity, specificity of the 22G Franseen needle combined with three different suction techniques (dry-suction…
- Trial name
- NCT07023549
- Testing
- ABC, ACB, BAC
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Changhai Hospital
Endoscopic Ultrasonography, Sedation
End-Tidal Carbon Dioxide Monitoring Device for Sedation During Endoscopic Ultrasonography
To meet the needs of both operators and patients, moderate and deep sedation has been widely used in digestive endoscopy, which is invasive and painful. With its pleasant effects, sedation has complications nevertheless.
- Conditions
- Endoscopic Ultrasonography, Sedation, Monitoring
- Trial name
- NCT04549623
- Testing
- Novel end-tidal CO2 monitoring device, SpO2 and respiratory motion monitoring
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Changhai Hospital
Pancreatic Cyst, Pancreatitis, Acute
Rectal Indomethacin to Prevent Acute Pancreatitis in EUS-FNA of Pancreatic Cysts
The aim of this randomized trial is to compare the rate of post-procedure pancreatitis in patients undergoing EUS-FNA of pancreatic cysts; patients will receive either a single dose of indomethacin or placebo administered…
- Trial name
- NCT05572788
- Testing
- EUS-guided fine needle aspiration of pancreatic cysts
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Orlando Health, Inc.
Satisfaction, Personal
3D Thyroid Education Model for Student
The purpose of our study is to develop a high-fidelity thyroid education model, that can be utilized for medical students/ PGY doctors/ residents training.
- Trial name
- NCT06147011
- Testing
- 3D printed educational model
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University
Mediastinum
EBUS-TBNA vs EUS-B-FNA for Needle Aspiration of Mediastinal Lesions
Endobronchial Ultrasound Guided Transbronchial Needle aspiration (EBUS-TBNA) is a firmly established modality for diagnostic evaluation of mediastinal lesions.
- Trial name
- TEAM (NCT02704078)
- Testing
- EBUS-TBNA, EUS-B-FNA
- Where
- India
- Volunteers
- 100 people
- Sponsor
- All India Institute of Medical Sciences
Biopsy, Fine-needle, Pancreatic Neoplasm
EUS-FNB for Solid Pancreatic Lesions: Side-fenestrated Vs Fork-tip Needle
Rationale: Until now there are no prospective studies comparing the 22 gauge and 25 gauge side-fenestrated and fork-tip needles.
- Trial name
- NCT03622229
- Testing
- Histologic evaluation
- Where
- 2 sites in Italy
- Volunteers
- 192 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
EUS-FNA, Cytodiagnosis
Comparison of EUS-Guided Fine Needle Aspiration Technique
EUS-guided fine needle aspiration (EUS-FNA) is a safe and effective method for diagnosing pancreatic and peripancreatic solid masses.
- Trial name
- NCT01923883
- Testing
- EUS-FNA, Echoendoscope Olympus GF-UCT240
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Asan Medical Center
Thyroid Nodule
Prediction of Thyroid Cancer From Ultrasonographic Characteristics of Thyroid Nodules
The aim of this study is to identify which ultrasonographic feature or a combination of features is the best predictor of thyroid cancer in thyroid nodules.
- Trial name
- NCT00571090
- Testing
- Thyroid ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 735 people
- Sponsor
- Istanbul Science University
Lesion Sampled for Cytology
Simple Technique to Improve Diagnostic Yield in EUS-FNA
Endoscopic ultrasound and fine needle aspiration are useful tools for the diagnosis and staging of pancreatic cancer. One potential limitation is contamination when needle traverses the gastrointestinal tract under continuous…
- Trial name
- NCT01995474
- Testing
- Twisted Syringe, Conventional Technique
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medical College of Wisconsin
Pancreatic Neoplasms
22 G - 25 G SINS Trial for Pancreatic Masses
After patients have been screened and have signed informed consent, they will be taken to the endoscopy suite. Once the decision has been made to proceed with Fine Needle Aspiration (FNA), the subject will be randomized to 1 of 4…
- Trial name
- SINS (NCT02424838)
- Testing
- EUS-FNA of pancreatic masses, 22 gauge needle, 25 gauge needle
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Pancreatic Solid Lesions
Prospective Comparison of Diagnostic Accuracy Between Contrast-enhanced Harmonic and Conventional EUS-guided Fine-needle Biopsy in Solid Pancreatic Lesions
Endoscopic ultrasonography (EUS)-guided fine-needle aspiration/biopsy (FNA/B) is used to collect biopsy samples from many organs throughout the digestive tract and is useful in diagnosing solid pancreatic lesions (SPLs).
- Trial name
- NCT04924725
- Testing
- Endoscopic ultrasound-guided fine needle biopsy
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Pancreatic Neoplasms, Mediastinal Neoplasms
22G-Adapt vs 22G-Franseen Needle Biopsy in EUS-Guided Tissue Acquisition of Solid Lesions
The investigators conduct a prospective, multicenter, blinded, randomized controlled trial to compare the diagnostic value and safety of the 22G Adapt needle versus the 22G Franseen needle for histopathological evaluation of…
- Conditions
- Pancreatic Neoplasms, Mediastinal Neoplasms, Abdominal Neoplasm, Excluding Pancreas Neoplasm
- Trial name
- NCT07012694
- Testing
- 22G Franseen Needle Group, 22G Adapt Needle Group
- Where
- China
- Volunteers
- 576 people
- Sponsor
- Huazhong University of Science and Technology
Breast Cancer
High Risk Breast Clinic: Protocol for Women at Increased Risk for Developing Breast Cancer
The overall goal of this project is to develop an integrative system of breast cancer risk assessment based on epidemiologic and biologic risk variables, as well as to develop or refine risk biomarkers which may be useful in…
- Trial name
- NCT00291096
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Pancreatic Neoplasm
EUS-FNA of Solid Pancreatic Mass: Comparison Between Negative Pressure and Slow-pull Technique
50 patients with pancreatic mass will undergo endoscopic ultrasound-guided fine needle aspiration using two techniques: negative pressure and slow-pull. Cytological results will be compared.
- Trial name
- EUS-FNA (NCT03111368)
- Testing
- Endoscopic ultrasound-guided fine needle aspiration
- Where
- Brazil
- Volunteers
- 1 people
- Sponsor
- University of Sao Paulo General Hospital
Lung Cancer
Utility of Endobronchial Ultrasound Guided Needle Biopsy in Early Stage Non- Small Cell Lung Cancer (NSCLC)
The goal of this clinical research study is to learn how accurately an endobronchial ultrasound transbronchial needle aspiration (EBUS -TBNA) may detect mediastinal lymph node metastases in patients with clinical stage I and II…
- Trial name
- NCT00832715
- Testing
- EBUS-TBNA
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- M.D. Anderson Cancer Center
Pancreatic Cancer, Pancreatic Adenocarcinoma
EUS-guided PORtal Vein Sampling for Circulating Tumor Cells in Pancreatic Cancer Patients
The study aims at evaluating the feasibility and safety of EUS-guided Portal Circulation sampling for isolation, enumeration and profiling od Circulating Tumor Cells (CTC) in Pancreatic Cancer patients.
- Trial name
- EUPhORIC (NCT05247164)
- Testing
- EUS-guided Portal Vein sampling
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- IRCCS San Raffaele
Thyroid Cancer, Atypia of Undetermined Significance
The Risk Stratification of Papillary Thyroid Cancer With AUS/FLUS by FNA
Purpose: To investigate the clinical characteristics of papillary thyroid cancer (PTC) with Bethesda category III (AUS/FLUS) by fine needle aspiration (FNA) and to assisted the precision treatment.
- Conditions
- Thyroid Cancer, Atypia of Undetermined Significance, FLUS
- Trial name
- NCT04601298
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Shanghai 10th People's Hospital
Pancreatic Cancer
Evaluation of Multiple Needle Use in EUS-FNA for Pancreatic Cancer
The aim of this study is to evaluate if the early change of needle during EUS-FNA for suspected pancreatic cancer allows an earlier preliminary cytological diagnosis of neoplasia.
- Trial name
- EMUNE-07 (NCT00548626)
- Testing
- Single needle, Multiple needle
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Chicago
Adenocarcinoma, Neuroendocrine Tumors
EchoTip AcuCore Post-Market Clinical Study
The purpose of collecting this data is to continue to learn more about the EchoTip AcuCore and the device's ability to produce the desired favorable effect and if there are any undesired outcomes that may be related to the…
- Conditions
- Adenocarcinoma, Neuroendocrine Tumors, Hepatocellular Carcinoma, Cholangiocarcinoma
- Trial name
- NCT06358001
- Testing
- EchoTip AcuCore
- Where
- 8 sites in United States
- Volunteers
- 183 people
- Sponsor
- Cook Research Incorporated