Clinical trials: Finger
Dupuytren Contracture, Dupuytren Disease of Finger
Safety and Efficacy Study of Collagenase CNT201 Injection for Treatment of Dupuytren's Contracture
This trial is a multicenter, Phase 1/2, study to assess the safety, tolerability, efficacy, PK, and immunogenicity of CNT201 in adult participants with DC (Dupuytren's Contracture).
- Trial name
- NCT07640425
- Testing
- [Step1] CNT201 First-dose, [Step1] CNT201 Low-dose, [Step1] CNT201 Intermediate-dose
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- CONNEXT
Healthy Volunteers (HV), Transcranial Photobiomodulation
Frequency-Dependent Effects of Transcranial Photobiomodulation on Cortical Excitability
This study aims to investigate the frequency-dependent effects of near-infrared (NIR) transcranial photobiomodulation (tPBM) on human cortical excitability and fine motor performance.
- Conditions
- Healthy Volunteers (HV), Transcranial Photobiomodulation, Cortical Excitability
- Trial name
- NCT07707284
- Testing
- Transcranial Photobiomodulation
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Conservatively Treated Mallet Finger Injury
Conservative Treatment of Mallet Finger Injury
Comparing outcomes of individuals treated with Kinesiotape and oval 8 versus quick cast for a conservatively managed mallet finger injury. Outcomes include DIP joint extension lag, patient satisfaction and function via the MHQ.
- Trial name
- NCT04830917
- Testing
- Immobilization type for mallet injury
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Orthopaedic Specialty Group PC, Fairfield
Soft Tissue Defect of the Finger
A Comparison of Dorsal Branch of the Digital Nerve Versus Dorsal Digital Nerve for Finger Pulp Reconstruction
As the donor nerve attached with the flap, the dorsal branch of the digital nerve and the dorsal digital nerve is commonly used for finger pulp reconstruction.This study compares two donor nerves: the dorsal branch of the digital…
- Trial name
- NCT01826539
- Testing
- flap includes a donor nerve
- Where
- China
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Dystonic Disorder, Focal Dystonia
Characterization of Manual Dexterity by Finger Force Manipuladum (FFM) in Patients With Writer's Cramp and in Control Subjects
Writer's cramp is a focal dystonia characterized by abnormal movements and postures during writing. Limited finger independence during writing manifests as difficulty suppressing unwanted activations of neighbouring non…
- Conditions
- Dystonic Disorder, Focal Dystonia, Writer's Cramp
- Trial name
- FFM_CT (NCT03797638)
- Testing
- Finger Force Manipuladum (FFM)
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Hiv
CD4 CAR+ ZFN-modified T Cells in HIV Therapy
This research study is being carried out to study a new way to possibly treat HIV. As part of this study, doctors will take some of your own white blood cells, called T-cells, and modify them so that they can identify and target…
- Trial name
- NCT03617198
- Testing
- CD4 CAR+CCR5 ZFN T-cells
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Pennsylvania
Healthy Volunteers
CYP2C9 Activity Evaluated With a Simple Finger Prick
The cytochrome P450 enzymes (CYP) are the major drug-metabolizing enzyme system in humans. A great inter- individual variability affects the activity of these enzymes, and consequently the plasma drug concentrations resulting in…
- Trial name
- NCT01026714
- Testing
- flurbiprofen, flurbiprofen, rifampicin, flurbiprofen + fluconazole
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Pain, Fear
The Effect of ShotBlocker and Finger Puppet on Pain and Fear During Blood Drawing in Children
Blood sampling can cause pain, anxiety, and fear in children. Such negative experiences may cause the child to develop negative attitudes toward treatment and care procedures.
- Conditions
- Pain, Fear, Blood Sampling, Children
- Trial name
- NCT07654192
- Testing
- Distraction techniques
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Laceration of Skin, Anesthesia, Local
Double-dorsal Versus Single-volar Digital Block
The aim of this study is to compare the traditional dorsal double injection digital block with the palmar single injection technique in the suturing of acute traumatic hand finger lacerations in terms of injection pain score…
- Conditions
- Laceration of Skin, Anesthesia, Local, Pain, Nerve Block
- Trial name
- NCT06274073
- Testing
- Dorsal digital block, Palmar digital block
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ankara City Hospital Bilkent
Human Papillomavirus-Related Malignant Neoplasm
Study of Molecular-targeted Therapy Using Zinc Finger Nuclease in Cervical Precancerous Lesions
This research study is being carried out to study a new way to possibly treat human cervical intraepithelial neoplasia (CIN) without invasion.
- Trial name
- NCT02800369
- Testing
- ZFN-603 and ZFN-758
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Huazhong University of Science and Technology
Hand Deformities
Prevention of Post-Stroke Hand/Wrist Flexion Deformity
The study looks at a new treatment for wrist and finger contractures -- a condition where the affected hand is in a "closed" position, with the wrist and fingers stiff and difficult to move from that position.
- Trial name
- NCT00628537
- Testing
- BION stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Southern California
Amputation; Traumatic, Hand
Validation of Point Partial User Needs With Partial Finger Amputees
The objective of the device feasibility study will be to validate the user needs of the Point Partial system. This study will be a single group intervention model where one group of 5 partial finger amputees will be asked to…
- Trial name
- NCT05012657
- Testing
- Point Partial
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Point Designs
Transplantation
Innervated Sensory Cross-Finger Flap
The purpose of this study is to introduce a new operative technique for reconstruction of fingertip degloving injury.
- Trial name
- ISCF (NCT01019811)
- Testing
- The innervated sensory cross-finger flap
- Where
- China
- Volunteers
- 16 people
- Sponsor
- The Second Hospital of Tangshan
DeQuervains Tenosynovitis, Lateral Epicondylitis
Dexamethasone Versus Ketorolac Injection for the Treatment of Local Inflammatory Hand and Upper Extremity Disorders
The primary objective of this study is to compare local corticosteroid hand and elbow injections to placebo or ketorolac to determine if there is an equal or better reduction of symptoms for common orthopaedic upper extremity…
- Conditions
- DeQuervains Tenosynovitis, Lateral Epicondylitis, Tennis Elbow, Trigger Finger
- Trial name
- NCT02266433
- Testing
- Ketorolac, Dexamethasone
- Where
- United States
- Volunteers
- 245 people
- Sponsor
- NYU Langone Health
Scleroderma, Systemic
Treprostinil Iontophoresis : a Pharmacodynamic and Pharmacokinetic Study
The purpose of the study is to assess skin blood flow after non-invasive local administration of treprostinil by using a low-intensity current (i.e.
- Trial name
- TIPPS (NCT01554540)
- Testing
- Cutaneous iontophoresis of treprostinil
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Moyamoya Disease, Intracranial Atherosclerotic Stroke
Moyamoya Disease Biomarkers in Patients With Intracranial Atherosclerotic Stroke
The aim of this study is to investigate the proportion of patients with moyamoya disease among the patients who were diagnosed as having intracranial atherosclerotic stroke.
- Conditions
- Moyamoya Disease, Intracranial Atherosclerotic Stroke, Intracranial Steno-occlusive Disease
- Trial name
- NCT02074111
- Where
- South Korea
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Dupuytren Disease of Palm and Finger, With Contracture
Hand Therapy or Not Following Collagenase Treatment for Dupuytren's Contracture?
This study evaluates if hand therapy have an impact on the patients' preformance of and satisfaction with everyday activities or not following collagenase injection treatment for Dupuytren's contracture.
- Trial name
- NCT03580213
- Testing
- Hand therapy MCPJ affected, Hand therapy PIPJ affected
- Where
- Norway
- Volunteers
- 72 people
- Sponsor
- Haukeland University Hospital
Osteoarthritis
A Soft Robotics Approach Towards Finger Joint Deformities in Rheumatic Diseases
The study is to investigate the effect of a soft robotic glove approach providing continuous passive motion of fingers (flexion and extension) on degenerative arthritis patients.
- Trial name
- NCT03326817
- Testing
- Control Group, Soft Robotic Glove Group
- Where
- Singapore
- Volunteers
- 8 people
- Sponsor
- National University Hospital, Singapore
Trigger Digit
Efficacy of Ultrasound Guided Hyaluronic Injection in Treatment of Trigger Finger
Comparing the Efficacy of Ultrasound Guided Hyaluronic Injection with Ultrasound Guided Corticosteroid Injection in Treatment of Trigger Finger
- Trial name
- NCT03131882
- Testing
- Hyaluronic Acid, Triamcinolone Acetonide
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Mahidol University
Low-Birth-Weight Infant, Breast Feeding
Finger Feeding as a Method of HMF Supplementation After Discharge
Human Milk Fortifier (HMF) is designed to supply additional calories, protein, vitamins and minerals to infants less than 37 weeks gestation or those less than 1500 g at birth.
- Trial name
- NCT04036240
- Testing
- Finger feeding
- Where
- 4 sites in Indonesia
- Volunteers
- 78 people
- Sponsor
- Fakultas Kedokteran Universitas Indonesia