Clinical trials: Fissure Sealant
Fissure Sealant
Glass Ionomer-Based Fissure Sealants in Children
This study aimed to comparatively evaluate the 24-month clinical retention performance and caries-preventive efficacy of three glass ionomer-based fissure sealants with different compositions.
- Trial name
- Sealant (NCT07388472)
- Testing
- Retention of Fissure Sealants
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Dental Caries
Effectiveness of Fissure Sealant and Topical Fluoride Application in Preventing Dental Caries
Nearly half of the 12-year-old children in China have dental caries (tooth decay) and most of the lesions are in the fissures of the first permanent molars.
- Trial name
- NCT01446107
- Testing
- placement of fissure sealant, fluoride varnish, silver fluoride
- Where
- China
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Molar Incisor Hypomineralization
Clinical Evaluation of Giomer and Resin-based Fissure Sealants
The objective of this research was to evaluate the clinical success of giomer and resin-based sealants applied in the first permanent molars (FPMs) affected by MIH.
- Trial name
- NCT04929782
- Testing
- Resin-based sealant, Giomer sealants
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Hacettepe University
Fissure Sealant
Effect of Er:YAG Laser on Hydrophilic Sealants
This study was conducted on 44 (19 girls and 25 boys) patients presenting 132 permanent first molars, who applied for oral examination to Adnan Menderes University Faculty of Dentistry Department of Pediatric Dentistry.
- Trial name
- NCT03718689
- Testing
- Laser etching
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Fissure Sealant, Deproteinization
Evaluation of the Survival of Fissure Sealants Applied With Different Pretreatment Methods on Permanent First Molars: A One-Year Follow-Up
Objective: This study aims to evaluate the effect of two different pretreatment protocols-enamel deproteinization and bonding agent application-on the one-year survival of fissure sealants applied to permanent first molars in…
- Conditions
- Fissure Sealant, Deproteinization, Bonding Agent, Molar Teeth
- Trial name
- NCT07136051
- Testing
- Ethcing, Deproteinization, Bonding
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Handan Vural
Fissure Sealant
The Effect of Different Deproteinising Agents on the Clinical Success of Fissure Sealants in Permanent Teeth
Investigation of the effect of deproteinization agents on the clinical success of non-invasive fissure sealant application, which is a non-invasive method used to prevent caries formation or to stop the progression of initial…
- Trial name
- NCT06988098
- Testing
- application of deproteinization agents
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Dental Caries
Randomized Clinical Trial of Occlusal Sealant
This study assessed long-term impact of tooth Eruption Stages (ES) on sealant retention on occlusal surfaces previously coated with intermediary bonding layer and it determined caries incidence outcome evolved.
- Trial name
- NCT02589743
- Testing
- Sealant, Adhesive and Sealant
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Caries Pit and Fissure, Dental Caries in Children
Occlusal Caries Management in First Permanent Molars in Child Dental Care
Occlusal caries management in first permanent molars: a pragmatic randomized clinical trial in child dental care Aim of the present study is to evaluate the effectiveness of fissure sealants and fluoride varnish in a pragmatic…
- Trial name
- FISSURE (NCT03315312)
- Testing
- Fluoride Varnishes, Fissure Sealants
- Where
- Norway
- Volunteers
- 410 people
- Sponsor
- Oral Health Centre of Expertise in Eastern Norway
Caries Prevention
Comparison of the Efficacy of Three Preventive Methods to Reduce the Incidence of Coronal Caries in Schoolchildren
The objective of this clinical trial is to compare the efficacy of three preventive methods in reducing the incidence of coronal caries in the first permanent molars of Mexican schoolchildren.
- Trial name
- NCT07131358
- Testing
- Glass ionomer pit and fissure sealant plus fluoride varnish, Pit and fissure sealant with Giomer® technology, Fluoride varnish
- Where
- 3 sites in Mexico
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Pit and Fissure Sealant Retention, Dental Caries
Clinical Evaluation of the Retention of Fissure Sealants Applied Following Guided Biofilm Therapy and Conventional Polishing
This randomized split-mouth clinical trial will compare two methods of occlusal surface cleaning before pit and fissure sealant placement in children aged 6-10 years.
- Trial name
- NCT07725133
- Testing
- Device: Guided Biofilm Therapy with erythritol, Device: Conventional Polishing
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
Fissure Sealant, Glass-ionomer Cement
Efficacy of Glass-ionomer Fissure Sealants
Despite numerous techniques for enamel protection, occlusal caries still remains a problem. Sealing pits and fissures is considered to be an effective way of preventing caries development.
- Conditions
- Fissure Sealant, Glass-ionomer Cement, Permanent Molar
- Trial name
- NCT03235960
- Testing
- glass-ionomer fissure sealant
- Where
- Serbia
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Association of Paediatric and Preventive Dentists of Serbia
Dental Caries on Pit and Fissure Surface
Effectiveness of Fissure Sealants Bonded With Different Universal Adhesives
The purpose of this study is to evaluate and compare the clinical retention of a resin-based fissure sealant placed with prior application of etch-and-rinse and self-etch modes of universal adhesives.
- Trial name
- NCT02897089
- Testing
- Adhesive agent
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Caries Prevention
Comparing Bond Strength,Microleakage and Clinical Performance of Three Pit and Fissure Sealants
The aim of the study is :- 1. To evaluate and compare the microleakage of three different fissure sealants(resin-based Clinpro sealant, Moisture tolerant resin-based Embrace WetBond sealant and glass ionomer Fuji Triage sealant)…
- Trial name
- NCT04272866
- Testing
- Clinpro sealant, Embrace wetbond sealant, Triage sealant
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sarah Emad Ali El-Din
Molar Incisor Hypomineralisation, Children
This Study Aims to Evaluate the Effect of Rinsing Off or Blot-drying Silver Fluoride on the Retention of Subsequently-applied Resin- and Glass Ionomer-based Fissure Sealants in Permanent Molars Affected by Molar-Incisor Hypomineralization.
The aim of this study is three-fold: 1. To evaluate the clinical performance of glass ionomer fissure sealants and resin fissure sealants when placed immediately after or one week following the application of silver fluoride on…
- Conditions
- Molar Incisor Hypomineralisation, Children, Dental Caries
- Trial name
- NCT06641011
- Testing
- Immediate restoration (resin- based) after blot-drying silver fluoride application, Immediate restoration (GI- based) after blot-drying silver fluoride application, Immediate restoration (Resin based) after rinsing silver fluoride application
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Caries
Comparison Between Resin Based and Glass Ionomer Based Hydrophilic Fissure Sealants
The aim of the study is to clinically evaluate the retention and caries formation of hydrophilic fissure sealants among adolescents after one year.
- Trial name
- NCT05127343
- Testing
- Sealing deep pits and fissures
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries,Dental, Pit and Fissure Caries
Retention of a Flowable Resin-based Sealant With Two Types of Adhesives
The aim of the present study is to compare the use of two adhesives for the placement of occlusal sealants, evaluating their retention on the occlusal surfaces.
- Conditions
- Caries,Dental, Pit and Fissure Caries, Sealant Dental
- Trial name
- NCT04945382
- Testing
- Scotchbond Universal 3M, Single Bond 3M
- Where
- Peru
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University of San Marcos, Peru
Dental Caries, Fissure Sealant
The Effect of an Adhesive System on the Retention and Caries Prevention for Fissure Sealants in Permanent Molars
Background: Resin-based fissure sealants (FS) are recommended to prevent pit-and-fissure caries development or prevent the progression of enamel caries lesion to frank cavitation into dentine.
- Trial name
- ResinFS (NCT06608563)
- Testing
- Fissure sealant without adhesive system (NO BOND), Fissure sealant with adhesive system (BOND)
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Molar Hypomineralization, Incisor, Fissure Sealant
Clinical Evaluation of Two Fissure Sealants (Resin Based Versus Giomer Fissure Sealants) on Molar Incisor Hypominerlisation Affected Permanent Molars (RCT)
This study aims to compare the effect of two types of fissure sealant a resin based and giomer based in molar incisor hypominerlisation first permanent molars
- Conditions
- Molar Hypomineralization, Incisor, Fissure Sealant, Resin Based Sealers
- Trial name
- MIH RCT (NCT07732790)
- Testing
- Resin based fissure sealant (Fisseal), Giomer based fissure sealant ( Beautisealant)
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- National Research Centre, Egypt
Pit and Fissure Caries (Disorder), Pit and Fissure Sealants
Evaluation of the Clinical Success of Hydrophilic Fissure Sealants
The study group will consist of children aged 7-11 years who are systemically healthy and who apply to the Pediatric Dentistry Clinic of the Faculty of Dentistry, Afyonkarahisar Health Sciences University for routine dental…
- Trial name
- NCT07262502
- Testing
- pit and fissure sealant
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Dental Enamel, Dental Enamel Hypomineralization
Retention of Pits and Fissure Sealants on Non Carious vs Initial Carious Enamel Lesions in Posterior Teeth
This clinical study is planned to be conducted to compare retention rates of pits and fissure sealants on non carious (ICDAS score 0) vs Initial carious enamel lesions (ICDAS Score 1,2) in posterior permeant teeth at 3 months, 6…
- Conditions
- Dental Enamel, Dental Enamel Hypomineralization, Dental Enamel Hypoplasia
- Trial name
- NCT07330089
- Where
- Pakistan
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad