Clinical trials: Fistula-in-ano
Anal Fistula Surgery, Anal Fistula
Impact of Surgical Timing on Anal Fistula Outcomes
This study aims to evaluate if the amount of time a person experiences symptoms of an anal fistula before having surgery affects their surgical outcomes and recovery.
- Conditions
- Anal Fistula Surgery, Anal Fistula, Surgery Timing
- Trial name
- NCT07482241
- Volunteers
- 90 people
- Sponsor
- Assiut University
Fistula in Ano
Fistulotomy With Marsupialization Versus Fistulectomy With Wound Sutures in Simple Anal Fistula
comparison between fistulectomy wound closure and fistulotomw wound marsupialization in treatment of simple anal fistula
- Trial name
- NCT04215718
- Testing
- fistulotomy and marsupialization, fistulectomy and wound closure
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Zagazig University
Anal Fistula
Autologous Stem Cells Derived From Lipoaspirates for the Non-Surgical Treatment of Complex Perianal Fistula
This comparative, multicentre, randomised clinical trial is designed with two parallel groups that will follow a treatment either with an autologous implant of ASCs (Adipose Derived Stem Cells) and fibrin glue (tissue adhesive…
- Trial name
- NCT00115466
- Testing
- Non-surgical autologous implant of ASCs
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Cellerix
Anal Fistula
Endorectal Three-dimensional Ultrasound in the Diagnosis of Cryptogenic Fistulas of the Rectum.
Prospective comparative parallel ultrasound diagnostic transrectal study in the diagnosis of cryptogenic fistulas of the rectum
- Trial name
- NCT03743701
- Testing
- The method of transrectal ultrasound in В-mode, The method of transrectal ultrasound examination using three-dimensional image reconstruction.
- Where
- Russia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Fistula in Ano
Role of Udumbara Sutra in the Management of Fistula in Ano a Rare Case Study
The anal fistula is a notorious disease due to its recurrence rate. Bhagandara is varyingly defined as a tear, ulcer or boil at Bhaga (Perianal region) within 2 finger circumference of it, causing painful abscess when opened is…
- Trial name
- Bhagandara (NCT01954225)
- Testing
- Udumbara Sutra
- Where
- India
- Volunteers
- 1 people
- Sponsor
- Government Ayurved College and Hospital
Anal Fistula
3D Endoanal Ultrasound and Anal Fistula
The study aims to evaluate the use of 3D endoanal ultrasound in preoperative management of anal fistula disease.
- Trial name
- UFU (NCT03937752)
- Testing
- 3D endodanal ultrasound
- Where
- Sweden
- Volunteers
- 95 people
- Sponsor
- Region Skane
Anal Fistula
Re-routing in Treatment High Anal Fistula
The aim of this study is to evaluate the role of rereouting in treatment of high anal fistula and evaluate the success rate, the recurrence and incontinence and see if rerouting of the track is a good choice in treatment of high…
- Trial name
- NCT05476146
- Testing
- Rerouting of the track in high anal fitula
- Volunteers
- 50 people
- Sponsor
- Assiut University
Fistula in Ano, Transsphincteric Anal Fistula
Treatment of Fistula in Ano With Autologous Fatty Tissue Cells Transplantation
This is a prospective interventional study on the treatment of transsphincteric fistula in ano. After abdominal or thigh liposuction, fat was injected around the fistula tract that was then transected percutaneously with a sharp…
- Trial name
- NCT04660903
- Testing
- Autologous fat cell transplantation
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Konstantinos Tsimogiannis
Fistula-in-ano
BioHealx® Anal Fistula Device Post Market Surveillance Study
This post market surveillance study is a single arm multicenter study to demonstrate the long-term durability and effectiveness of the BioHealx Anal Fistula Device for fistula-in-ano closure (internal and external fistula…
- Trial name
- NCT07021742
- Testing
- BioHealx
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Signum Surgical USA Inc.
Anal Fistula
A Randomized Clinical Trial Comparing Surgisis AFP to Advancement Flap for the Repair of Anal Fistulas
The purpose of this study is to determine whether the Surgisis anal fistula plug is just as effective in healing anal fistulas as compared to the advancement flap procedure.
- Trial name
- Surgisis® AFP (NCT00545441)
- Testing
- Surgisis Biodesign Anal Fistula Plug (Surgisis® AFP), Flap
- Where
- 6 sites in Germany
- Volunteers
- 86 people
- Sponsor
- Cook Group Incorporated
Anal Fistula, Treatment
The Efficacy of Human Acellular Dermal Matrix in the Treatment of Anal Fistula
The purpose of this study is to determine whether human acellular dermal matrix plug is effective in the treatment of anal fistula
- Conditions
- Anal Fistula, Treatment, Postoperative Complications, Acellular Dermal Matrix
- Trial name
- NCT00951002
- Testing
- acellular dermal matrix plug
- Where
- 13 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Zhen Jun Wang
Anal Fistula, Fecal Incontinence
Gore-BioA Fistula Plug to Treat Transsphincteric Fistulas
This is a prospective clinical study on the efficacy of Gore-BioA fistula plug in high transsphincteric fistulas. Follow-up time is six months
- Conditions
- Anal Fistula, Fecal Incontinence, Surgery
- Trial name
- NCT01584752
- Testing
- Gore-BioA Fistula Plug
- Where
- 7 sites in Finland
- Volunteers
- 60 people
- Sponsor
- Central Finland Hospital District
Rectal Fistula
Photodynamic Therapy in Anal Fistula
Objective: Validate and analyze the results of intralesional photodynamic therapy in the treatment of complex anal fistula. Methods: Prospective observational study including patients treated for complex anal fistula who…
- Trial name
- NCT03864718
- Testing
- photodynamic therapy
- Volunteers
- 49 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Complex Anal Fistulas
Fistura® Procedure for the Treatment of Complex Anal Fistulas
This study aims to evaluate the healing rate of complex fistulas using radiofrequency (Fistura® procedure), in a prospective, interventional, monocenter, single-arm design.
- Trial name
- NCT06113068
- Testing
- Fistura® procedure
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- F Care Systems NV
Anal Fistula
LIFT With or Without Injection of BM-MNCs
To improve the outcome of LIFT, some authors used a combined approach of LIFT. Pooled analysis of seven studies including 192 patients revealed a success rate of 83.5 % after combined LIFT approach.
- Trial name
- NCT05134168
- Testing
- bone marrow mononuclear cell injection, LIFT
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Anal Fistula
Ligation of Intersphincteric Fistula Tract (LIFT) Procedure Versus Use of an Anal Fistula Plug for Anal Fistula Repair
Anal fistulae are a difficult problem to treat. The optimal treatment for fistula involving the anal sphincter is unclear. Two standardly used methods of treatment are the ligation of intersphincteric fistula track (LIFT)…
- Trial name
- LIFT vs PLUG (NCT00830661)
- Testing
- Ligation of intersphincteric fistula track procedure, anal fistula plug
- Where
- 4 sites in United States, Canada
- Volunteers
- 124 people
- Sponsor
- Colon and Rectal Surgery Associates, Ltd.
Anal Fistula
Randomized Trial on the Effect of Topical Phenytoin on Healing After Fistulotomy
Patients with anal fistula who will undergo anal fistulotomy will be randomized into one of two groups; the first group will receive topical phenytoin therapy postoperatively and the second group will not receive such topical…
- Trial name
- NCT03096522
- Testing
- Phenytoin 2% spray, Anal fistulotomy
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Mansoura University
Anal Fistula
Anal Fistula Plug Versus Endorectal Advancement Flap
The purpose of this study is to determine whether anal fistula plug or endorectal advancement flap is more successful in the treatment of anal fistulas and compared both procedures with regards to cost.
- Trial name
- AFPERAF (NCT01931371)
- Testing
- Anal Fistula Plug, Endorectal Advancement Flap
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- University of Zurich
Crohn Disease (CD)
Tolerance of Local Administration of Cryopreserved Autologous Stromal Vascular Fraction Combined With Micrograft for the Treatment of Refractory Ano-perineal Fistulas in Crohn's Disease
The ADICROHN-3 study is a prospective, multicenter, open-label cohort study. Its design is supported by the following elements: The results of the ADICROHN pilot study (EudraCT No.
- Trial name
- ADICROHN3 (NCT07629245)
- Testing
- injection of thawed SVF
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Anal Fistula
Treatment of Anal Fistulas Advancement Flap
This study comprises a prospective study of 40 patients with transphincteric anal fistula. The patients were classified into two groups: Group I: Fistulectomy, closure of internal sphincter and rectal advancement flap includes…
- Trial name
- flap (NCT01042821)
- Testing
- partial rectal wall advancement flap, mucosal advancement flap
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University