Clinical trials: Fistula-in-ano
High Complex Anal Fistula
Decompression and Drainage Seton in the Treatment of High Complex Anal Fistula
This study aimed to compare the efficacy of the decompression and drainage seton (DADS) and cutting seton (CS) in the treatment of high complex anal fistula.
- Trial name
- NCT05087407
- Testing
- Decomprssion and drainage seton, Cutting seton
- Where
- China
- Volunteers
- 120 people
- Sponsor
- China-Japan Friendship Hospital
Anal Fistula, Complex Perianal Fistulas
Evaluate the Distribution and Dynamic Behavior of TH-SC01 Cells in Vivo in Patients With Perianal Fistula
The purpose of this study is to evaluate the distribution and dynamic behavior of Nuclide labeled TH-SC01 cells in vivo in patients with perianal fistula
- Conditions
- Anal Fistula, Complex Perianal Fistulas, Crohn's Disease
- Trial name
- NCT06429241
- Testing
- Mesenchymal Stem Cells (MSCs)
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Jiangsu Topcel-KH Pharmaceutical Co., Ltd.
Crohn Disease, Perianal Fistula
Micro-fragmented Adipose Tissue and Complex Crohns' Anal Fistulas
The study aims to evaluate safety, feasibility and effectiveness of local injections of autologous and micro-fragmented adipose tissue obtained with the Lipogems® system in patients with refractory complex fistulizing perianal…
- Trial name
- NCT03555773
- Testing
- Lipogems
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Wound Healing, Fistulectomy
Comparison of Wound Healing in Fistulectomy and Fistulectomy With Marsupialization
The study was done at Central Park Medical College Lahore during January to September, 2024. Low fistula-in-ano patients were randomized into 2 groups i.e. Group A (SUR 1 fistulectomy) and Group B (170 patients in each group).
- Conditions
- Wound Healing, Fistulectomy, Fistulectomy With Marsupialization, Fistula in Ano
- Trial name
- NCT07080424
- Testing
- Fistulectomy with Marsupialization, Fistulectomy
- Where
- Pakistan
- Volunteers
- 340 people
- Sponsor
- Central Park Medical College
Perianal Fistula, Anal Fistula
Laser Ablation Versus Conventional Fistulectomy for Uncomplicated Perianal Fistula
This randomized controlled trial aims to compare conventional open fistulectomy and laser ablation in the treatment of uncomplicated perianal fistula.
- Trial name
- NCT07681531
- Testing
- Laser ablation, Conventional Open Fistulectomy
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- PNS Hafeez - Naval Hospital
Crohn's Disease, Peri-anal Fistulas
Investigation of Sexual Function in Crohn's Disease Patients With Perianal Fistulas
Objective: The aim of this study is to investigate whether Crohn's Disease patients with peri-anal fistulas will suffer from sexual dysfunction in an attempt to help us identify Crohn's Disease patients that would benefit from…
- Conditions
- Crohn's Disease, Peri-anal Fistulas, Sexual Dysfunction
- Trial name
- NCT01635543
- Where
- Canada
- Sponsor
- University of British Columbia
Anal Fistula
Multicenter Prospective Evaluation of Radiofrequency for Anal Fistulas
Anal fistula treatment is associated with increasing risk of anal incontinence until 40% of cases. New and alternative treatments (glue, advancement flap, plug…) decrease this risk, but with fistula efficacy treatment in 40 to…
- Trial name
- RADIOFIST (NCT03131297)
- Testing
- treatment by radiofrequency
- Where
- 4 sites in France
- Volunteers
- 50 people
- Sponsor
- F Care Systems NV
Perianal Fistula, Anxiety
Video-Based Preoperative Education for Anxiety in Patients Undergoing Anal Fistula Surgery
This study evaluated whether video-based education before surgery could reduce anxiety and improve early recovery in patients undergoing anal fistula surgery under spinal anesthesia.
- Trial name
- NCT07914530
- Testing
- Video-Based Perioperative Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Afyonkarahisar Health Sciences University
Complex Anal Fistula
Therapeutic Management of Complex Anal Fistulas by Installing a Closure Clip: Multicentre Randomized Controlled Trial
Anal fistulas are the main etiology of perianal abscesses and suppurations. They are common and generally associated with pain, anal incontinence, impaired quality of life and work incapacity.
- Trial name
- FISCLOSE (NCT02336867)
- Testing
- Closure clip (OTSC® Proctology)
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Clermont-Ferrand
Anal Fistula
Ethibond Suture vs Vessel Loop as Draining Seton for Complex Anal Fistulas
Drainage seton is usually placed for long-term control of symptoms, and hence it has to be effective in drainage of infection, durable, and comfortable to the patients.
- Trial name
- NCT05933343
- Testing
- Ethibond suture, Vessel loop
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The Cleveland Clinic
FISTULA IN ANO
Comparison Between Laser and Open Fistula Surgeries in the Management of Fistula - In - Ano
This prospective randomized controlled trial compared the outcomes of laser versus open surgical techniques in the management of fistula-in-ano among 100 patients at a tertiary care center.
- Trial name
- NCT07083778
- Testing
- Laser Fistula Surgery (FiLaC - Fistula-tract Laser Closure), Open Fistula Surgery (Fistulotomy, Fistulectomy, or LIFT Procedure)
- Where
- India
- Volunteers
- 100 people
- Sponsor
- GSVM Medical College
Fistula in Ano, Crohn Disease
Autologous Stem Cells in the Management of Fistulating Perianal Crohn's Disease
Crohn's disease is a chronic inflammatory condition that can affect any part of the bowel which can be controlled by a combination of medical and surgical treatments but cannot be cured.
- Trial name
- NCT06822686
- Testing
- Harvest and injection of stem cells
- Sponsor
- Oxford University Hospitals NHS Trust
Anal Fistulas
Aspiration Treatment of Perianal Abscess
The purpose of this study is to compare aspiration and oral antibiotics with surgical incision in the treatment of perianal abscesses in terms of recurrence and subsequent fistula formation.
- Trial name
- NCT02585141
- Testing
- MEDIPLAST® (aspiration), incision, Clindamycin
- Where
- Denmark
- Volunteers
- 111 people
- Sponsor
- University of Southern Denmark
Fistula in Ano
Management of Fistula in Ano by Kshar Sutra, Para Surgical Procedure.
Background: Fistula in ano is one of the most common diseases of the ano rectal region. Treatment of Fistula in ano has puzzled the medical fraternity due to its complex nature.
- Trial name
- Bhagandar (NCT01880398)
- Testing
- Kshar Sutra
- Where
- India
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Government Ayurved College and Hospital
Fistula in Ano
Fistulotomy Versus Fistulotomy With Marsupialization
It was a study comparing two standard procedures for fistula in ano
- Trial name
- NCT05660876
- Testing
- standard fistulotomy, fistulotomy with marsupialization
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- DHQ mardan
Fistula in Ano
High Type Fistula in Ano, Use Staged Seton, Loose Thick Sutures
Fistula in ano is a chronic problem for the patients. It causes distressing because of foul odor and soiling with recurrent infection and discharge.
- Trial name
- NCT05223309
- Testing
- Usinf thick loose sutures in seton techingues
- Where
- Iraq
- Volunteers
- 100 people
- Sponsor
- Jabir Ibn Hayyan Medical University
Anal Fistula
Randomized Trial on the Effect of Topical Phenytoin on Healing After Fistulotomy
Patients with anal fistula who will undergo anal fistulotomy will be randomized into one of two groups; the first group will receive topical phenytoin therapy postoperatively and the second group will not receive such topical…
- Trial name
- NCT03096522
- Testing
- Phenytoin 2% spray, Anal fistulotomy
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Mansoura University
Fistula Perianal
Human Placenta Mesenchymal Stem Cells Derived Exosomes Injection for Treatment of Complex Anal Fistula
The goal of this clinical trial is to learn if human placenta mesenchymal stem cells (MSC)-derived exosomes work to treat complex perianal fistula in adults without Crohn's disease.
- Trial name
- NCT06568653
- Testing
- exosome, routine conventional fistulotomy
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Anal Fistula
Study on Repeat Liposomal Bupivacaine for Post-Surgery Pain in Anal Fistula Patients.
Anal Fistula refers to an abnormal infectious fistula tract between the anorectum and the perianal skin. The prevalence of anal fistula is approximately 8.6 cases per 100,000 individuals.
- Trial name
- NCT07081373
- Testing
- A single dose of liposomal bupivacaine is administered at the conclusion of surgery without adjunctive analgesics, followed by a supplemental dose 72 hours postoperatively.
- Where
- China
- Volunteers
- 408 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Anal Fistula
Surgisis Anal Fistula Plug Study: An Experience in Saudi Arabia
The Surgisis Anal Fistula Plug study is a clinical trial conducted in Saudi Arabia to study the safety and effectiveness of the Surgisis AFP Plug in the treatment of chronic anal fistulas.
- Trial name
- SurgiSIS AFP (NCT00703131)
- Testing
- Anal Fistula Plug (SurgiSIS AFP)
- Where
- Saudi Arabia
- Volunteers
- 35 people
- Sponsor
- Cook Group Incorporated