Clinical trials: Flexible Ureteroscopy
Kidney Stones
Flexible Ureteroscopy With a Flexible and Navigable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for 1-2 cm Lower Pole Kidney Stones
This study, known as the FLAME Trial (Flexible ureteroscopy for Lower pole stones And Mini-pErcutaneous nephrolithotomy), is an international, multicenter, randomized, non-inferiority trial.
- Trial name
- FLAME (NCT07159035)
- Testing
- Flexible ureteroscopy with FANS, Mini-percutaneous nephrolithotomy (mini-PCNL)
- Where
- China
- Volunteers
- 640 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Renal Calculi
Suctioning Flexible Ureteroscopy With Intelligent Control of Renal Pelvic Pressure
This study evaluates the safety and efficacy of the suctioning flexible ureteroscopy(SF-URS) with automatic control of renal pelvic pressure for the treatment of upper urinary calculi using a prospective, randomized design.
- Trial name
- NCT02734914
- Testing
- SF-URS with automatic control of RPP, conventional F-URS
- Volunteers
- 60 people
- Sponsor
- The Affiliated Ganzhou Hospital of Nanchang University
Pediatric Urolithiasis, Kidney Stone
Standard Versus Flexible and Navigable Suction Ureteral Access Sheath in Pediatric Flexible Ureterorenoscopy for Renal Stones < 2 cm
This randomized controlled trial aims to compare the efficacy and safety of a Flexible and Navigable Suction Ureteral Access Sheath (FANS) versus a standard ureteral access sheath during flexible ureterorenoscopy (FURS) in…
- Conditions
- Pediatric Urolithiasis, Kidney Stone, Nephrolithiasis
- Trial name
- FANS-UAS (NCT07689565)
- Testing
- Standard Ureteral Access Sheath (Boston Scientific)., Flexible and Navigable Suction UAS (ClearPetra).
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Nephrolithiasis, Kidney Calculi
Ureteral Access Strategies in Retrograde Intrarenal Surgery
Retrograde intrarenal surgery (RIRS) is a standard minimally invasive treatment for kidney stones up to 20 mm. During the procedure, irrigation fluid raises the pressure inside the kidney and laser energy raises the fluid…
- Conditions
- Nephrolithiasis, Kidney Calculi, Retrograde Intrarenal Surgery, Flexible Ureteroscopy
- Trial name
- NCT07898020
- Testing
- Flexible and navigable suction ureteral access sheath, Conventional ureteral access sheath, Sheathless flexible ureteroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Ondokuz Mayıs University
Flexible Ureteroscopy
Preoperative Prediction of Flexible Ureteroscopy Outcome in the Treatment of Renal Calculi
To predict the outcome of flexible ureteroscopy in the management of renal stones based on preoperative scoring module using five preoperative parameters that have effect on stone free status postoperatively.
- Trial name
- NCT05857501
- Testing
- abdominopelvic computerized tomography (CT) without contrast
- Volunteers
- 72 people
- Sponsor
- Menoufia University
Upper Urinary Tract Urothelial Carcinoma, Bladder Cancer
Single-Dose Intravesical Chemotherapy After Diagnostic URS
Study design This study is a Phase III, randomized, open-label, multi-center, global study to determine the efficacy of a single immediate intravesical chemotherapy instillation (SI) in the prophylaxis of intravesical recurrence…
- Trial name
- MINERVA (NCT05810623)
- Testing
- Intravesical Solution
- Where
- 2 sites in Austria
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- David D'Andrea
Urolithiasis, Kidney Stone
Flexible Ureteroscopy With Tip-bendable Suction Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for Treatment of 2-3cm Renal Stones
Background: Percutaneous nephrolithotomy (PCNL) is the first-line treatment for renal stones larger than 2 cm according to EAU and AUA guidelines.
- Trial name
- NCT06526390
- Testing
- f-URS, mini-PCNL
- Where
- China
- Volunteers
- 720 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Circulatory; Change
Effects of Flexible Ureteroscopy on Renal Blood Flow
Aim of this study is to investigate the effects of increased intrarenal pressure during flexible ureteroscopy on renal blood flow.
- Trial name
- NCT03023488
- Testing
- flexible ureteroscopy, Doppler Ultrasound examination, laser lithotripsy
- Volunteers
- 46 people
- Sponsor
- Marmara University
Extracorporeal Shockwave Lithotripsy, Flexible Ureteroscopy
Flexible urétéroscopy Versus Extracorporeal Shockwave Lithotripsy in Renal Calculi
Flexible ureteroscopy is a recent procedure to treat renal stone. Extracorporeal shockwave lithotripsy was the gold standard treatment for calculi between 5 and 20 mm.
- Trial name
- CALIX-1 (NCT01604304)
- Testing
- flexible ureteroscopy, extracorporeal shockwave lithotripsy
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Stone, Kidney
Effectiveness of Self-posturotherapy on the Elimination of Residual Fragments After Treatment of Lower Calyx Urinary Stones by Extracorporeal Lithotripsy or Retrograde Flexible Ureteroscopy.
The main objective of this study is to evaluate the effectiveness of an auto posturotherapy technique on the RFS at three months of patients treated for lower calyceal urinary stones by extracorporeal lithotripsy (ECL) or…
- Trial name
- ALUR (NCT06793540)
- Testing
- SELF POSTUROTHERAPIE
- Where
- 2 sites in France
- Volunteers
- 216 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Urolithiasis, Calyx; Calculus
Citrate Salts for Stone-free Result After Flexible Ureterorenoscopy for Inferior Calyx Calculi
The prevalence of urolithiasis is around 10 % in the French population. It is thus a major public health issue. When the stone is not spontaneously removed, interventions such as extracorporeal lithotripsy or flexible…
- Trial name
- CiRUS (NCT04021381)
- Testing
- Potassium and magnesium citrate
- Where
- France
- Volunteers
- 262 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Renal Calculi, Nephrolithiasis
Comparison Between Different Types of Flexible Ureteroscopes
The current study aims to compare the performance of three distinct single-use digital flexible ureteroscope types in terms of cost-effectiveness, postoperative complications, operating time, and stone-free rates (SFRs).
- Trial name
- FURS (NCT07360353)
- Testing
- LithoVue™ (Boston Scientific Corporation), WiScope® (OTU Medical Inc. (Silicon Valley, USA)), Single-Use Ureterorenoscope (Scivita Medical Technology Co., Ltd.)
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Kidney Stone
LithoVue Single Use Disposable Ureteroscope
Most flexible ureteroscopes that are used to treat kidney stones have been reusable. Recently, advances in technology have resulted in single-use (disposable) ureteroscopes to become available.
- Trial name
- NCT03419091
- Testing
- single-use flexible digital ureteroscope, Reusable Ureteroscope
- Where
- 2 sites in United States, Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Kidney Calculi
Flexible Ureteroscopy for Large Renal Stones in Children
This prospective single-arm interventional study evaluated the efficacy and safety of flexible ureteroscopy for the treatment of large renal stones measuring 2 cm or more in pediatric patients.
- Trial name
- NCT07780409
- Testing
- Flexible Ureteroscopic Stone Disintegration
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Kidney Stones, Nephrolithiasis
Comparing Efficiency and Stone-Free Rates Mini PCNL vs Flex URS
The objective of the study is to compare the stone free rates with ureteroscopy utilizing the ClearPETRA suction ureteral access sheath, and mini-PCNL; both procedures and ClearPETRA sheaths are standard of care and are used…
- Conditions
- Kidney Stones, Nephrolithiasis, Urolithiasis
- Trial name
- NCT07072598
- Testing
- ClearPETRA suction access sheath
- Where
- United States
- Sponsor
- Northwestern University
Kidney Stone
Impact of Forced Diuresis on the Residual Fragment Rate After Flexible Ureteroscopy for Destruction of Kidney Stones With Laser
In view of the positive results of the numerous studies conducted on forced diuresis after extra-corporeal lithotripsy, the investigators chose to evaluate forced diuresis by injection of Furosemide associated with intravenous…
- Trial name
- FIREStones (NCT05916963)
- Testing
- Furosemide 40 mg
- Where
- 9 sites in France
- Volunteers
- 374 people
- Sponsor
- University Hospital, Tours
Kidney Stone, Kidney Calculi
Outcomes of Using FANS With FURS in TTT of Lower Calyceal Stones.
The aim of this study is to evaluate and assess the outcomes of flexible ureteroscopy (FURS) with flexible and navigable suction UAS (FANS) in the treatment of lower calyceal stones.
- Trial name
- NCT07238803
- Testing
- flexible and navigable suction sheath with flexible ureteroscopy
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Zagazig University
Kidney Calculi
Assessment of Flexible Ureteroscopy Residual Fragments
Residual fragments of urinary calculi after flexible ureteroscopy (URF) can cause symptoms and additional surgeries. The assessment of residual fragments by imaging is not standardized.
- Trial name
- NCT02434068
- Testing
- CT
- Where
- Brazil
- Volunteers
- 115 people
- Sponsor
- University of Sao Paulo General Hospital
Renal Stone
Robotic Flexible Ureteroscopy Versus Standard Flexible Ureteroscopy for Renal Stones
This is a prospective randomized clinical trial which aims to compare the clinical outcomes of robotic flexible ureteroscopy and standard flexible ureteroscopy for the treatment of renal stones.
- Trial name
- NCT06660914
- Testing
- Flexible Ureteroscopy
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Chinese University of Hong Kong
Kidney Stone
Tip Bendable Suction Ureteral Access Sheath vs. Traditional Ureteral Access Sheath in Retrograde Intrarenal Stone Surgery
Nephrolithiasis is the most common chronic kidney condition and affecting approximately one in every 10-17 people in the world[1,2].
- Trial name
- NCT05952635
- Testing
- Tip bendable suction ureteral access sheath
- Where
- China
- Volunteers
- 320 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University