Clinical trials: Fluid Challenge
Fluid Responsiveness
Fluid Responsiveness in Prone Patients
To assess fluid responsiveness in prone patient
- Trial name
- NCT06254456
- Testing
- End expiratory occlusion test
- Volunteers
- 84 people
- Sponsor
- Bhumibol Adulyadej Hospital
Fluid Challenge, Hemodynamic Monitoring
Tidal Volume Challenge and Lung Recruitment Maneuver (TIDALREC): the Reliability of Pulse Pression Variation or Stroke Volume Variation on Fluid Responsiveness.
In order to predict fluid responsiveness in the operating room and therefore benefit of performing fluid administration to improve patient's hemodynamic status, it will test two ventilation strategies : the Tidal Volume Challenge…
- Trial name
- TIDALEC (NCT04535115)
- Testing
- Starting LRM (Lung Recruitment Maneuver), Starting VtC (Tidal Volume Challenge)
- Where
- France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Lille
To Assess the Ability of PI to Detect Preload Responsiveness
Changes in Pulse-Oximetry Perfusion Index Induced by Tidal Volume Challenge Versus Fluid Volume Challenge to Detect Preload Responsiveness in Mechanically Ventilated Patients With Low Tidal Volume
The primary goal of this study was to assess the ability of PI changes induced by a Vt challenge or fluid challenge test to detect preload responsiveness in critically ill adult patients on mechanical ventilation with low-tidal…
- Trial name
- NCT06673862
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Benha University
Septic Shock
Does the Time Between the End of Vascular Filling and Evaluation of Its Effectiveness Modify Fluid Challenge Results in Septic Shock?
The main objective of this study is to evaluate in a population of patients with septic shock receiving 500 ml crystalloid over 10 minutes, the proportion of patients classified as "responders" to the fluid challenge (increase of…
- Trial name
- FC-Rev (NCT02116413)
- Testing
- Fluid challenge, Cardiac ultrasound
- Where
- 9 sites in France
- Volunteers
- 145 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hemodynamic Instability, Anesthesia
Mini Fluid chAlleNge and End-expiratory Occlusion Test and to Assess flUid responsiVEness in opeRating Room
End-expiratory occlusion test (EEOT) has been previously successfully tested in surgical patients, consisting of the interruption of the mechanical ventilation for 30 seconds, and in the evaluation of the changes in the SV.
- Conditions
- Hemodynamic Instability, Anesthesia, Surgery
- Trial name
- MANEUVER (NCT03808753)
- Testing
- End-expiratory occlusion test (EEOT), mini fluid challenge (mFC)
- Where
- 3 sites in Italy
- Volunteers
- 103 people
- Sponsor
- Humanitas Clinical and Research Center
Septic Shock
Guided Fluid-balance Optimization With Mini-fluid chALlenge During Septic Shock
Many observational studies have highlighted an independent association between fluid overload and clinical outcomes during septic shock.
- Trial name
- GOAL (NCT03461900)
- Testing
- Minifluid challenge, Usual practice
- Where
- 18 sites in France
- Volunteers
- 535 people
- Sponsor
- University Hospital, Brest
Sepsis, Shock, Septic
"Mini Fluid Challenge Assessment: a Comparison Among Three Hemodynamic Tools"
The mini fluid challenge (mini_FC) is a functional hemodynamic test which has been used in different clinical contexts to assess fluid responsiveness.
- Conditions
- Sepsis, Shock, Septic, Critically Ill
- Trial name
- MINI3 (NCT04934943)
- Testing
- mini_FC
- Where
- 2 sites in Italy
- Volunteers
- 45 people
- Sponsor
- Humanitas Clinical and Research Center
Mini-fluid Challenge in Video-Assisted Thoracic Surgery
The Effectiveness of Mini-fluid Challenge in Predicting Fluid Responsiveness During Video Assisted Thoracic Surgery
Perioperative fluid management is crucial for patients' outcome. Muller et al developed a "Mini-fluid challenge method " to predict fluid responsiveness and the efficacy.
- Trial name
- NCT03731377
- Testing
- Crystalloid Solutions
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Anesthesia
Does the Response to a Mini-fluid Challenge of 3ml/kg in 2 Minutes Predict Fluid Responsiveness for Pediatric Patient?
To predict fluid responsiveness in anesthetized pediatric patient is not an easy task although anesthesia provider has to deal with this question on their daily practices.
- Trial name
- PEDIFLUID (NCT02894996)
- Testing
- fluid challenge
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Volume Overload
Inferior Vena Cava Diameter Dependent Colloid Challenge Versus Routine Crystalloid Strategy Transurethral Resection Prostate
Background: Intravenous fluid replacement during transurethral resection of the prostate is still unclear. Ultrasonography of the inferior vena cava (IVC) has been recently used to assess the volume status and predict fluid…
- Trial name
- NCT04131361
- Testing
- Ultrasound-guided Inferior vena cava diameter dependent colloid challenge versus routine crystalloid strategy Fluid replacement
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mansoura University
Intraoperative Care, Fluid Responsiveness
Short Time Low PEEP Challenge and Mini Fluid Challenge
Optimizing fluid therapy is one of the main concerns for anesthesiologists during the intraoperative period. It becomes even more important in high-risk long lasting surgeries as pancreaticoduodenectomy.
- Trial name
- NCT05419570
- Testing
- Fluid Loading
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Istanbul Saglik Bilimleri University
Post Cardiac Surgery
Minimal Volume for Fluid Challenge in Post-operative Patients
This study evaluate the effect of different doses of crystalloids on the changes on cardiac output (CO) and on the proportion of responders and non-responders and aims to determine the minimal volume required to increase the mean…
- Trial name
- NCT02569008
- Testing
- Fluid challenge with Compound Sodium Lactate
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- St George's, University of London
Severe Sepsis or Septic Shock in Pediatric Intensive Care Unit
Predictive Mini-bolus Fluid Responsiveness in Pediatric Septic Shock
Severe sepsis and septic shock remain of particular gravity in children with a current mortality of about 20 % , despite the international prevention campaigns " survival sepsis campaign ".
- Trial name
- PRECISE (NCT04027699)
- Testing
- Mini-bolus
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intravenous Fluids, Pharmacodynamics
Effect of Oral Water in Healthy Volunteers on Cardiac Output, Regional Flow and Microcirculation in Healthy Volunteers
Human digestive system physiologically ensures the absorption of oral water and hydration of the human body. Water is quickly absorbed by the digestive tract with a peak between 15 and 20 minutes.
- Conditions
- Intravenous Fluids, Pharmacodynamics, Fluid Therapy, Fluid Responsiveness
- Trial name
- WATERNAL (NCT05153837)
- Testing
- saline intravenous administration, oral water
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Septic Shock
The Effect of Rapid Fluid Challenge Under Pulmonary Artery Catheter Monitoring on Physiological Indexes of Patients With Septic Shock
Fluid challenge is often carried out in septic shock patients. Its responsiveness usually requires invasive monitoring. The pulmonary artery catheter(PAC) is the most effective means of monitoring.To use non-invasive methods is…
- Trial name
- NCT03661268
- Testing
- fluid chanllenge
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chengdu Fifth People's Hospital
Acute Circulatory Failure During One-lung Ventilation Surgery
Use of Mini-fluid Challenge for Fluid Responsiveness Prediction During One-lung Ventilation
During thoracic surgery, an excessive use of fluid results in pulmonary complications. Dynamic fluid responsiveness predictors are not easily usable during one lung ventilation.
- Trial name
- NCT02858115
- Testing
- Fluid challenge, Trans-oesophageal echography
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Septic Shock
The Validity of Peripheral Perfusion Index to Predict Fluid Responsiveness
Fluid therapy is an essential component of the management of patients with acute circulatory failure. Nevertheless, unnecessary administration of fluids in non-responders is harmful.
- Trial name
- NCT03805321
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Cairo University
Fluid Challenge, Pharmakodynamic
EFFECT OF VASOPRESSORS ON FLUID CHALLENGE PERSISTENCE AN OBSERVATIONAL STUDY IN PATIENTS UNDERGOING LAPAROTOMY.
The hemodynamic effect of the fluid challenge administration (FC) depends on different variables related to the interplay between cardiac function and vascular tone response.
- Conditions
- Fluid Challenge, Pharmakodynamic, Norepinephrine, Surgery
- Trial name
- NORA_FC (NCT04934345)
- Testing
- Fluid challenge
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Humanitas Clinical and Research Center
Anesthesia
Mini-fluid Challenge as a Predictor of Fluid Response for Pneumoperitoneum Patient
The purpose of this study is to evaluate whether the change of stroke volume index(△SVI) induced by the rapid mini-fluid administration can predict fluid responsiveness in patients with pneumoperitoneum
- Trial name
- NCT03843411
- Sponsor
- Changhua Christian Hospital
Anomaly; Venous Return
Volume-challenge in Morbid Obesity
Preoperative venous return stability and euvolemia is essential in management of morbidly obese patients. Fluid therapy regimes for patients with high BMI, especially with focus on preoperative management, are rare and not in…
- Trial name
- NCT01748513
- Testing
- preoperative venous return optimizing
- Where
- Sweden
- Volunteers
- 34 people
- Sponsor
- Umeå University