Clinical trials: Fluid Loss
Fluid Loss, Enhanced Recovery
Role of Goal Directed Fluid Therapy in Enhanced Recovery After Surgery in Gastro-intestinal Oncosurgeries
Enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery and reducing postoperative morbidity after surgical procedures by maintaining preoperative organ…
- Trial name
- GDFT ERAS (NCT06026475)
- Testing
- Goal directed Fluid Therapy, Conventional Fluid Therapy
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Obesity
Cerebrospinal Fluid Biomarkers in Bariatric Surgery
The goal of this project is to understand why bariatric surgery is such an effective treatment for obesity with a focus on brain mechanisms.
- Trial name
- NCT04350892
- Testing
- Roux-en-Y Gastric Bypass (RYGB), Sleeve Gastrectomy (SG), Very Low Calorie Diet (VLCD)
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Columbia University
Vascular Filling, Newborn
Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life
At birth, the infant's weight was measured daily to assess the adequacy of nutritional intake. This indicator can be influenced by various factors related to the mother, her pregnancy, as well as medical interventions during the…
- Conditions
- Vascular Filling, Newborn, Weight Loss, Jaundice
- Trial name
- PERLE (NCT07243054)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cataract
The Effect of Hydrodynamic Parameters on Corneal Endothelial Cell Loss After Phacoemulsification
The purpose of this study is to compare two surgical techniques (high vacuum and low vacuum) on corneal endothelium after phacoemulsification.
- Trial name
- NCT00370955
- Testing
- phacoemulsification using either high vacuum or low vacuum techniques
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Diabetes Mellitus, Type 2, Obesity
Influence of a Liquid Oat Bran Product on Blood Glucose in Patients With Poorly Controlled Type 2 Diabetes
This study evaluates the effects of an ad libitum addition of a high fiber product to the regular diet of type 2 diabetes patients on body weight and blood sugar control.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Overweight, Metabolic Syndrome
- Trial name
- NCT03805802
- Testing
- active product, reference product
- Where
- Germany
- Volunteers
- 34 people
- Sponsor
- Stoffwechselzentrum Rhein - Pfalz
Kidney Stones, Surgical Blood Loss
Combined Intravenous and Irrigation Tranexamic Acid During Percutaneous Nephrolithotomy
Percutaneous nephrolithotomy is a minimally invasive surgical procedure used to remove large kidney stones. Although it is an effective treatment, bleeding during and after the procedure remains one of the main concerns and may…
- Conditions
- Kidney Stones, Surgical Blood Loss, Percutaneous Nephrolithotomy
- Trial name
- NCT07582341
- Testing
- Tranexamic acid, Normal Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Benha University
Weight Loss
Cost Effectiveness of Nutrition Intervention in Long Term Care
Inadequate food and fluid intake is a common problem among nursing home (NH) residents and one that can lead to under-nutrition, dehydration, weight loss, hospitalization, and even death.
- Trial name
- NCT02567526
- Testing
- Between-Meal Intervention Group
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Blood Loss, Surgical, Fluid Retention
Impact of Hyperoncotic Albumin to Support Blood Loss Replacement
Fluid treatment is usually performed with either balanced crystalloid fluids or iso-oncotic colloids, (synthetic colloids, plasma and 5% albumin).
- Trial name
- HYPALB (NCT03848507)
- Testing
- albumin 20%
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Bone Loss, Hypotensive
Blood Flow and Bone Density in Healthy Adult Women
This project will test the efficacy of using a non-invasive neuromuscular stimulation on the plantar surface of the feet to prevent and/ or reverse bone loss in a sample of healthy adult women.
- Conditions
- Bone Loss, Hypotensive, Lower Limb Fluid Pooling
- Trial name
- NCT00397462
- Testing
- calf muscle pump stimulation
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Binghamton University
Fluid Loss
Evaluation of Physiological Variables and Detection of Blood Loss Using the Zynex Fluid Monitoring System, Model CM-1600
The study is a prospective, non-randomized, non-blinded, non-significant risk, multi-center study enrolling up to 500 healthy adult subjects consented to undergo a whole blood donation procedure.
- Trial name
- NCT05463198
- Testing
- CM-1600
- Where
- 4 sites in United States
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Zynex Monitoring Solutions
Obesity
Effects of Re-Feeding Duration on Weight Maintenance After Weight Loss With Very-Low-Energy Diets (VLEDs)
The primary objective of the study is to test the hypothesis that prolonged re-feeding after VLED induced weight loss improves weight maintenance and eating behaviour
- Trial name
- NCT00694811
- Testing
- Re-feeding duration
- Where
- Sweden
- Volunteers
- 169 people
- Sponsor
- Göteborg University
Coronary Artery Disease, Coronary Artery Bypass
Impact of Fluid Restriction Policy in Reducing the Use of Red Cells in Cardiac Surgery
The investigators' hypothesis is that restriction of circulating fluids in comparison to a liberal fluid administration policy would lead to a reduction of allogenic red blood cells exposure in patients undergoing cardiopulmonary…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass, Erythrocyte Transfusion
- Trial name
- NCT00600704
- Testing
- Fluid Restriction Policy, Free fluid infusion
- Where
- Greece
- Volunteers
- 192 people
- Sponsor
- Larissa University Hospital
Periodontal Bone Loss, Chronic Periodontitis
Treatment of Intrabony Periodontal Defects With Enamel Matrix Derivatives and Autogenous Bone Graft
The present study aimed to evaluate the effects of enamel matrix derivatives either alone or combined with autogenous bone graft applied to intrabony defects in chronic periodontitis patients on clinical/radiographic parameters…
- Trial name
- NCT02218515
- Testing
- Open Flap Debridement, EmdogainⓇ(Enamel Matrix Derivative), EmdogainⓇEnamel Matrix Derivative+Autogenous Bone
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Haner Direskeneli, Prof
Idiopathic Intracranial Hypertension
Surgical Idiopathic Intracranial Hypertension Treatment Trial
Randomized trial of adults (≥18 years old) with idiopathic intracranial hypertension and moderate to severe visual loss without substantial recent treatment who are randomly assigned to (1) medical therapy, (2) medical therapy…
- Trial name
- SIGHT (NCT03501966)
- Testing
- Acetazolamide, Optic Nerve Sheath Fenestration, Ventriculoperitoneal CSF Shunting
- Where
- 36 sites in United States, Canada and 1 more
- Volunteers
- 7 people
- Sponsor
- Jaeb Center for Health Research
Weight Loss
Cost-Effectiveness of Weight Loss Prevention in Nursing Homes: A Controlled Trial
Low oral food and fluid intake and unintentional weight loss are common problems among long-stay nursing home (NH) residents and are associated with adverse, costly clinical outcomes.
- Trial name
- NCT02567513
- Testing
- Supplement Intervention, Snack Intervention
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Intraoperative Bleeding
Epinephrine in Irrigation Fluid for Visualization During Ankle Surgery
The purpose of this study is to evaluate the effect of epinephrine in irrigation fluid for visual clarity in ankle arthroscopic surgery.
- Trial name
- NCT06264596
- Testing
- Epinephrine, Normal Saline irrigation fluid
- Where
- United States
- Sponsor
- The Guthrie Clinic