Clinical trials: Fluid Therapy DURING SURGERY
Abdominoplasty
Fluid Therapy and Glycocalyx Shedding During Moderate Surgery
Goal-directed fluid therapy is one of the most accepted strategies in intraoperative fluid therapy, although potential fluid overload is a possible drawback.
- Trial name
- NCT05939518
- Testing
- Lactated Ringer's Fluid Bolus Response to Low Urinary Output, Post-Anesthesia Care Unit Lactated Ringer's Fluid Management Protocol
- Where
- Israel
- Volunteers
- 51 people
- Sponsor
- Hadassah Medical Organization
Periodontitis, Adult, Periodontal Diseases
Profiling Gingival Crevicular Fluid β-Catenin Level With 8-OHdG and Total Antioxidants Capacity During Healing of Periodontal Pockets: A 3-month Clinical Trial
Background: To profile gingival crevicular fluid (GCF) β-Catenin, 8-OHdG, and total antioxidants capacity (TAC) in periodontitis patients during healing of periodontal pockets following non-surgical periodontal therapy…
- Trial name
- NCT07596667
- Testing
- scaling and root planing
- Volunteers
- 21 people
- Sponsor
- Zeyad Nazar
Pancreatic Cancer, Resected, Whipple Procedure
A Study Comparing Restrictive and Liberal Fluid Therapy During Pancreatecoduodenectomy Surgery
ancreaticoduodenectomy (also known as PD or the Whipple procedure) is a major surgery often done for conditions like pancreatic cancer.
- Trial name
- NCT07072897
- Testing
- Fluid bolus administration, Frusemide was given when required
- Where
- Nepal
- Volunteers
- 44 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Hemodynamic Instability
Descending Aorta Blood Flow to Guide Fluid Therapy During Surgery
The investigators will perform a clinical observational study of patients undergoing abdominal surgery. The study will be performed at Sykehuset Telemark, Skien.
- Trial name
- NCT05227729
- Testing
- Measurement of blood flow in descending aorta by suprasternal ultrasound Doppler technique, Measurement of blood flow in descending aorta by transoesophageal ultrasound Doppler technique
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Sykehuset Telemark
Hypotension During Surgery
Goal-directed Fluid Therapy During Deep Inferior Epigastric Perforator (DIEP) Free Flap Breast Reconstruction
Adequate free flap perfusion during Deep Inferior Epigastric Perforator (DIEP) flap breast reconstruction surgery requires maintaining blood pressure above 100 mmHg and avoiding excessive fluid administration.
- Trial name
- GDFT DIEP-flap (NCT06080178)
- Testing
- Plasma-lyte (static group), Norepinephrine (static group), Plasma-lyte (dynamic group)
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Neoplasm, Cancer
Using Artificial Intelligence to Guide Fluid Therapy During Major Cancer Surgery: A Randomized Controlled Trial
The goal of this clinical trial is to learn if using artificial intelligence to guide intravenous fluid therapy during major cancer surgery can help keep blood pressure more stable compared with usual care in adult patients…
- Conditions
- Neoplasm, Cancer, Hemodynamic (MAP) Stability, Cancer Surgery
- Trial name
- FOCUS-AFM (NCT07314853)
- Testing
- Artificial Intelligence-Assisted Fluid Management, Standard fluid management
- Where
- Italy
- Volunteers
- 176 people
- Sponsor
- National Cancer Institute, Naples
Fluid Overload
Restrictive or Doppler-guided Fluid Treatment in Colorectal Surgery
This is a clinical randomised double blinded multicentre trial of two different fluid treatments during colorectal surgery in an enhanced recovery programme A restricted fluid regimen aiming at zero fluid balance and less than…
- Trial name
- NCT03677622
- Testing
- Voluven to near maximal stroke volume of the heart
- Volunteers
- 150 people
- Sponsor
- Holbaek Sygehus
Colorectal Cancer, Urologic Cancer
Fluid Challenge and Plasma Volume, During Surgery
A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique.
- Conditions
- Colorectal Cancer, Urologic Cancer, Gynecologic Cancer, Colorectal Disorders
- Trial name
- FC-VE (NCT05726136)
- Testing
- acetated Ringers, albumin 5%, albumin 20%
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Joachim Zdolsek
Goal-directed Fluid Therapy, Hemodynamics Instability
Multi-center Trial of Goal-directed Fluid Management Based on Pulse Pressure Variation Monitoring
Background: Intraoperative fluid therapy guided by mechanical ventilation-induced pulse-pressure variation (PPV) may improve outcomes after major surgery. It was tested this hypothesis in a multi-center study.
- Conditions
- Goal-directed Fluid Therapy, Hemodynamics Instability, High-risk Surgery, Pulse-pressure Variation
- Trial name
- GDTPPV (NCT03128190)
- Testing
- Pulse pressure variation monitoring
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Instituto de Assistencia Medica ao Servidor Publico Estadual, Sao Paulo
Ovarian Neoplasm, Fluid Therapy
Fluid Balance During Surgery for Ovarian Cancer
Extensive tumour debulking challenges both surgeon and anaesthesiologist but promotes survival in late-stage ovarian cancer patients.
- Trial name
- NCT03006939
- Testing
- Cytoreductive surgery
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University Hospital, Bonn