Clinical trials: Fluoride
Caries,Dental
Clinical Evaluation of Silver Nanoparticles in Comparison to Silver Diamine Fluoride in Management of Deep Carious Lesions
this clinical study will be carried out to evaluate the effect of fluoride varnish with silver nanoparticles in comparison to silver diamine fluoride in management of deep carious lesions.
- Trial name
- NCT05231330
- Testing
- silvernanoparticles, SDF
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Tooth Erosion
Intra Oral Kinetics of Fluoride Containing Dentifrices
The aim of this study is to assess the impact of formulation differences on fluoride retention clearance with US levels of fluoride (1150 ppm of fluoride) by evaluating and comparing between treatments the concentrations of…
- Trial name
- NCT02548156
- Testing
- Test Dentifrice, Reference Dentifrice, Comparator Dentifrice
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Oral Malodor
A Clinical Study Conducted in the Bangkok, Thailand Area, to Investigate the Clinical Efficacy of a New Toothpaste
To investigate the clinical efficacy of a new toothpaste containing 0.454% stannous fluoride as compared to a regular fluoride toothpaste containing 0.76% sodium monofluorophosphate on oral malodor reduction via organoleptic…
- Trial name
- NCT07223073
- Testing
- 0.454% stannous fluoride, 0.76% sodium monofluorophosphate
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Caries in Children
Efficacy of Silver Diamine Fluoride and Its Parental Perception
This randomized clinical trial aims to compare the effectiveness of two topical fluoride application protocols, namely 38% silver diamine fluoride and sodium fluoride with added casein phosphopeptide-amorphous calcium phosphate…
- Trial name
- NCT04213573
- Testing
- silver diamine fluoride, MI Varnish
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dentin Sensitivity
A Clinical Study to Evaluate the Effectiveness of an Test Toothpaste for the Relief of Dentin Hypersensitivity in a Chinese Population
The purpose of this study is to evaluate the clinical efficacy of a 0.454 percent (%) weight/weight (w/w) stannous fluoride (SnF2) toothpaste in reducing dentin hypersensitivity (DH) to an evaporative (air) stimulus and tactile…
- Trial name
- NCT07352956
- Testing
- Test toothpaste, Sodium fluoride toothpaste
- Where
- China
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- HALEON
SDF
KAP for Use of SDF Among Dental Interns Before vs After Educational Intervention
This study is a KAP questionnaire to assess Egyptian intern dentists' knowledge, attitudes and practices regarding use of SDF before and after an educational intervention.
- Trial name
- NCT06300931
- Testing
- educational lecture
- Volunteers
- 638 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar Incisor Hypomineralisation
Hydroxyapatite vs Fluoride Toothpaste for MIH Remineralization
Molar Incisor Hypomineralization (MIH) is a common developmental enamel defect affecting children, particularly in Dubai, where it contributes to hypersensitivity, esthetic concerns, plaque accumulation, and increased caries…
- Trial name
- MIH-CARE (NCT07177053)
- Testing
- non fluoridated hydroxyapatite tooth paste (KAREX KINDER tooth paste), fluoridated toothpaste (Colgate Total PROTECTION ACTIVE)
- Volunteers
- 160 people
- Sponsor
- Dubai Health
Arthropathy of Lumbar Facet, Pain, Back
Diagnostic Value of 18F-Fluoride-PET/MRI in the Management of Suspected Facet Joint Arthropathy
Prior to the injection, the facet joints have to be defined according to standard radiological techniques (e.g. MRI and physical correlation).
- Trial name
- NCT03317275
- Testing
- 18F-Fluoride-PET/MRI, facet injection, pain assessment by VAS
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Balgrist University Hospital
Dentin Sensitivity
Clinical Study to Evaluate the Anti-sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical Dentin Hypersensitivity (DH) efficacy of a 0.454 percent (%) Stannous Fluoride (SnF2) toothpaste.
- Trial name
- NCT06359028
- Testing
- Stannous fluoride toothpaste, Crest cavity protection toothpaste
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- HALEON
Dental Caries
Effective Fluoride Concentration In Toothpaste For Dental Caries Prevention
to identify the Effective Fluoride Concentration In Toothpaste For Dental Caries Prevention after 18 months of randomized controlled trial.
- Trial name
- DMFT (NCT02016001)
- Testing
- toothpaste 1 with maximum fluoride concentration, toothpaste 2 with 1000 ppm of fluoride
- Where
- Pakistan
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Tooth Hypersensitivity
the Efficacy of Giomer Versus Sodium Fluoride in the Treatment of Hypersensitivity
to solve the problem of hypersensitivity, I will use two different materials ( Giomer versus Sodium Fluoride) and compare between their effects in reliving the symptoms
- Trial name
- NCT03818945
- Testing
- shofu PRG barrier coat, Sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries in Children
Staining Potential and Caries Arresting Effect of Silver Diamine Fluoride⁄Potassium Iodide and Silver Diamine Fluoride
the main objective of this study is to evaluate staining potential and Caries Arresting Effect of silver diamine fluoride⁄potassium Iodide and silver diamine fluoride in carious anterior primary teeth
- Trial name
- NCT04196829
- Testing
- silver diamine fluoride ⁄ potassium Iodide, Silver Diamine Fluoride
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hormone-Resistant Prostate Cancer, Metastatic Malignant Neoplasm in the Bone
Fluorine F 18 Sodium Fluoride Positron Emission Tomography in Evaluating Response to Dasatinib in Patients With Prostate Cancer and Bone Metastases
This phase II trial is studying how well fluorine F 18 sodium fluoride positron emission tomography (PET) works in evaluating response to dasatinib in patients with prostate cancer and bone metastases.
- Conditions
- Hormone-Resistant Prostate Cancer, Metastatic Malignant Neoplasm in the Bone, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer
- Trial name
- NCT00936975
- Testing
- Fluorine F 18 Sodium Fluoride
- Where
- 4 sites in United States
- Volunteers
- 18 people
- Sponsor
- National Cancer Institute (NCI)
Prostate Cancer, Fluorocholine
18F-fluorocholine and 18F-fluoride PET in Prostate Cancer
Prostate cancer remains to be a public health problem around the world. For patients with prostate cancer, diphosphonate bone scintigraphy (BS) and pelvic tomographic imaging are major imaging tools to evaluate the disease…
- Trial name
- NCT04340765
- Testing
- 18F-fluorocholine
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Caries
Parental Satisfaction of Hall Technique Versus SDF in the Management of Carious Primary Molars
The aim of this study is to assess parental satisfaction and duration of the procedure of Hall and silver diamine fluoride techniques in the treatment of carious primary molars with healthy pulp.
- Trial name
- NCT05249231
- Testing
- Silver diamine fluoride, Hall technique
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sodium Fluoride
The Effect of Sodium Fluoride Application on the Prevention of Radiation Caries in NPC Patients
To evaluate the efficacy of sodium fluoride to preventing radiation caries for patients with nasopharyngeal carcinoma receiving radiotherapy.
- Trial name
- NCT06174012
- Testing
- Sodium Fluoride
- Volunteers
- 135 people
- Sponsor
- Sun Yat-sen University
Extrinsic Dental Stain, Oral Hygiene
Study to Investigate the Stain Control of Two Stannous Fluoride Dentifrices
The purpose of this study is to evaluate and compare the stain build up of two stannous fluoride (SnF2) / sodium tripolyphosphate (STP) dentifrices of differing abrasivity levels, with a marketed standard fluoride dentifrice and…
- Trial name
- NCT03160703
- Testing
- Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), 2.0% abrasive silica, Stannous fluoride (SnF2, 0.454%), Sodium tripolyphosphate (STP, 5%), abrasive silica (3.5%), Sodium Monofluorophosphate (1000 ppm fluoride ), RDA~80
- Where
- Canada
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Dental Caries, Dental Caries of Root Surface
Silver Diamine Fluoride for Caries Prevention in Removable Partial Dentures Wearers
This study measures and compares the effect of silver diamine fluoride (SDF) on caries increment in removable partial denture wearers. Half of the participants will SDF and while the other half will receive placebo.
- Trial name
- NCT03185104
- Testing
- Silver Diamine Fluoride, Distilled Water
- Volunteers
- 196 people
- Sponsor
- The University of Hong Kong
Silver Diamine Fluoride
Clinical Effectiveness and Parental Acceptance of Silver Diamine Fluoride in Preschool Children: A Non-randomized Trial
Silver diamine fluoride (SDF) is a topical fluoride agent that has emerged in recent years and has a strong potential to arrest dentinal caries in early childhood caries.
- Trial name
- NCT06293547
- Testing
- Silver Diamine Fluoride
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
High Caries Risk Patients
Assessment of Inhibition of Biofilm Formation and Plaque Bacterial Count of Fluoride Varnish Containing Chlorhexidine and Cetylpyridinium Chloride Versus Conventional Fluoride Varnish
Two different Fluoride varnish systems(Fluoride varnish containing Chlorhexidine and Cetylpyridinium Chloride (CPC) and conventional fluoride) will be applied to high caries risk patients to assess their clinical effects on…
- Trial name
- NCT04254835
- Testing
- Cervitec F, Ivoclar Vivadent - Schaan Liechtenstein, Fluor Protector, Ivoclar Vivadent - Schaan Liechtenstein
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University