Clinical trials: Fluoride
Plaque, Dental, Gingivitis
To Assess the Efficacy of Two Brushing Regimens: in the Reduction of Established Dental Plaque and Gingivitis.
Triple Blinded Randomized Clinical trial study to assess the efficacy of two brushing regimens: 1) a toothpaste containing stannous fluoride and a standard manual toothbrush as compared to 2) a regular fluoride toothpaste and…
- Trial name
- NCT07605338
- Testing
- Colgate SNaP Total 10/10, 1.5 Taurate, Colgate Great Regular Flavor Toothpaste, Flat Trimmed Extra Clean TB
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Bone Cancer, Articular Disease
18F-sodium Fluoride (NaF) PET to Replace Bone Scintigraphy: Safety and Efficacy Assessment
18F-sodium fluoride (18F-NaF) was already investigated numerous times in the last 40 years as a PET alternative to standard 99m-technetium-derived bone scintigraphy.
- Conditions
- Bone Cancer, Articular Disease, Infectious Disease
- Trial name
- NCT04842071
- Testing
- 18F-sodium fluoride
- Where
- 2 sites in Canada
- Volunteers
- 2,500 people
- Sponsor
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
White Spot Lesion of Tooth
Remineralizing Effect of Different Silver-containing Agents on Initial Caries Lesions in Primary Teeth in Children
The aim of the present work is to study the effect of the application of Silver diamine fluoride (SDF) and a novel green synthesized Nano-silver fluoride (NSF) on early enamel lesions in primary teeth.
- Trial name
- NCT06489093
- Testing
- NSF, SDF+KI, Control group
- Where
- Bulgaria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
White Spot Lesions, Caries
Randomized Trial on Resin Infiltration in Deciduous Teeth
It was hypothesized that resin infiltration in conjunction with fluoride varnish treatment of smooth-surface caries lesions in deciduous teeth reduce considerably the progression of treated caries lesions, compared to fluoride…
- Trial name
- infiltration (NCT01881100)
- Testing
- resin infiltration, fluoride varnish
- Where
- Poland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Early Childhood Caries
Effect of Application Time of 38% Silver Diamine Fluoride Solution on Arresting Dental Caries in Preschool Childre
To determine the optimal application time of silver diamine fluoride (38% SDF) in arresting dental caries in the primary teeth of preschool children.
- Trial name
- NCT04655430
- Testing
- 3-second SDF application, 5-second SDF application, 10-second SDF application
- Where
- Hong Kong
- Volunteers
- 665 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Acute Charcot Neuroarthropathy
Clinico-Radiological Characterisation for Remission of Acute Charcot-Neuroarthropathy of Foot.
Charcot's neuro-arthropathy is a condition which is generally prevalent among the diabetic patients. Acute charcot's neuro-arthropathy is characterized by signs of inflammation, hot, red swelling around the involved joint along…
- Trial name
- NCT06017011
- Testing
- Total contact cast
- Where
- India
- Volunteers
- 25 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Dental Caries
Effect of Water Rinsing After Topical Fluoride Application on Dental Plaque pH
The aim of this study was to determine whether rinsing with water or cleansing teeth after topical fluoride therapy affect the dental plaque pH.
- Trial name
- NCT01569165
- Testing
- cleansing teeth after topical fluoride therapy
- Where
- Iran
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Deep Caries
Silver Diamine Fluoride After Minimal Caries Removal Technique in Asymptomatic Young Permanent Teeth With Deep Caries
This study is comparing between the Silver Diamine Fluoride after minimal caries removal versus glass ionomer in permanent teeth with open apex
- Trial name
- NCT03568474
- Testing
- Silver Diamine Fluoride, Glass Ionomer
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pit and Fissure Caries, Glass Ionomer Cements
Glass Ionomer Sealant Versus Fluoride Varnish on Occlusal Caries Prevention
The current study compares the efficacy of glass ionomer fissure sealant versus topical application of 5% sodium fluoride varnish in prevention of occlusal caries among preschool children.
- Conditions
- Pit and Fissure Caries, Glass Ionomer Cements, Tooth, Deciduous, Child
- Trial name
- NCT04163354
- Testing
- 5% sodium fluoride varnish (NaF), Glass ionomer sealant (GIS)
- Where
- Hong Kong
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
White Spot Lesion of Tooth
Effect of Self Assembling Peptide on White Spot Lesion
During re-mineralization of white spot lesion, Will biomimetic self-assembling peptides improve the re-mineralizating effect of the post orthodontic white spot lesion compared to fluoride-based delivery systems?
- Trial name
- regeneration (NCT03930927)
- Testing
- Self Assembling peptide, remineralizing agent
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Raneen Ahmed
Dental Caries in Children
Efficacy and Safety Evaluation of Anti-Caries Varnish
The purpose of the study is to determine the efficacy \& safety of Advantage Anti-Caries Varnish for primary prevention. The objectives are: 1) To determine if Advantage Anti-Caries Varnish (test varnish) is superior to an active…
- Trial name
- NCT04947527
- Testing
- Test varnish
- Where
- United States Minor Outlying Islands
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Advantage Silver Dental Arrest, LLC
Fluorosis, Dental, Fluorosis
Design of a Multicomponent Intervention to Reduce the Risk of Exposure Fluorine
Introduction Systemic exposure to fluoride is a significant challenge for global public health; this is because although fluoride prevents dental caries, prolonged exposure to high concentrations can cause adverse effects on…
- Trial name
- NCT07359937
- Testing
- multicomponent intervention, Conventional intervention
- Where
- Colombia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio Nariño
Dentin Hypersensitivity
Clinical Effectiveness of Episodic Use of Bioactive Silica Based Versus in Management of Dentin Hypersensitivity (A 6m Randomized Clinical Trial)
The aim of the study to compare the clinical effectiveness of Episodic use of Bioactive Silica Based versus continuous use of fluoride based desensitizing toothpastes in management of dentin hypersensitivity (DH) of adult…
- Trial name
- NCT07120139
- Testing
- episodic use of the desensitizing toothpaste, continuous use of the conventional desensitizing toothpaste
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz
Gingivitis, Plaque, Dental
Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste
The 6-month clinical study was designed to investigate clinical efficacy on plaque and gingivitis for the stannous fluoride containing toothpaste (SNAP) compared to Colgate Cavity Protection Toothpaste after 3 and 6 months of…
- Trial name
- NCT06300866
- Testing
- Test, Control
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Caries
Total Salivary Fluoride Concentration of Healthy Adult Subjects Following Toothbrushing With Different Formulations of Fluoridated Toothpastes With and Without Post-brushing Water Rinsing.
Caries prevalence has declined significantly since the introduction of fluoridated toothpastes. Since then, different toothpaste formulations and concentrations have been introduced to the market with varying levels of efficacy.
- Trial name
- NCT02740803
- Testing
- Sodium fluoride toothpaste 1,450 ppmF, sodium monofluorophosphate toothpaste 1,450 ppmF, stannous fluoride combined with sodium fluoride toothpaste 1,450 ppmF
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Dentin Sensitivity
Clinical Trial to Compare the Efficacy of a Fluoride Gel and a Dental Bonding Agent in Treatment of Tooth Sensitivity
This study compares the efficacy of two dental interventions in the treatment of cervical dentine sensitivity. The participants will be selected from adult dental patients registered at a general dental practice in West Sussex…
- Trial name
- NCT02919202
- Testing
- Colgate Fluoride Varnish Suspension. 2.26% Sodium Fluoride., Self-etching Dentine Bonding Agent
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Kent
Early Childhood Caries
Clinical Efficiency and Child's Behavior of Hall Versus SDF Techniques in the Management of Carious Primary Molar:
This study will compare two non- invasive treatment options: Hall technique and 38% Silver diamine fluoride. Both are methods used to create a more favorable environment without removal of caries leading to the arrest of the…
- Trial name
- NCT04737057
- Testing
- SDF, Hall technique
- Volunteers
- 72 people
- Sponsor
- Cairo University
Tooth Hypersensitivity
the Efficacy of Giomer Versus Sodium Fluoride in the Treatment of Hypersensitivity
to solve the problem of hypersensitivity, I will use two different materials ( Giomer versus Sodium Fluoride) and compare between their effects in reliving the symptoms
- Trial name
- NCT03818945
- Testing
- shofu PRG barrier coat, Sodium fluoride varnish
- Where
- Egypt
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries
A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children
The objective of this study is to assess the safety and to evaluate the anti-caries efficacy of COL101 (arginine) non-fluoride dentifrices compared to a 0.24% sodium fluoride dentifrice in 10-14 year-old children over a one year…
- Trial name
- NCT04750902
- Testing
- 0.24% Sodium Fluoride Dentifrice, 1.5% Arginine Dentifrice, 4.0% Arginine Dentifrice
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 2,025 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Sodium Fluoride
The Effect of Sodium Fluoride Application on the Prevention of Radiation Caries in NPC Patients
To evaluate the efficacy of sodium fluoride to preventing radiation caries for patients with nasopharyngeal carcinoma receiving radiotherapy.
- Trial name
- NCT06174012
- Testing
- Sodium Fluoride
- Volunteers
- 135 people
- Sponsor
- Sun Yat-sen University