Clinical trials: Fluoride
Hypersensitivity, Dentin Sensitivity
Clinical Assessment of Bifluorid 10 vs Varnish Fluoride on The Exposed Hypersensitive Cervical Dentin in Adult Patient
Aim of the study will be conducted to compare the efficacy of bifluoride (NaF and CaF) versus conventional fluoride varnish (Sodium Flouride) in the management of hypersensitivity of exposed cervical area in adult patients over 2…
- Trial name
- NCT04485299
- Testing
- Bifluorid 10 ,VOCO, Sodium Fluoride 5% Dental Varnish
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cairo University
Caries
In Situ Caries Efficacy of Fluoride Toothpastes
This study is to evaluate the effect of fluoride dentifrices on enamel with artificial caries lesions in an in situ model
- Trial name
- NCT00708097
- Testing
- NaF, NaMFP
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Caries,Dental, Remineralization
Remineralization Efficacy of Gum Arabic Varnish.
The aim of this study is to evaluate the remineralizing capacity of Gum Arabic varnish and its implementation into clinical practice.
- Conditions
- Caries,Dental, Remineralization, White Spot Lesion
- Trial name
- NCT04422860
- Testing
- Gum Arabic varnish, Proflourid Varnish,VOCO, MI Varnish,GC Japan Inc.
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Halitosis
A Clinical Study to Examine the Effects of an Experimental Toothpaste Compared to a Regular Fluoride Toothpaste on Breath Odor in a Population With Gingivitis
The purpose of this study is to investigate the efficacy of an experimental dentifrice, containing 0.454 percent (%) stannous fluoride and 0.3% zinc chloride, to reduce oral malodor, compared to a marketed regular fluoride…
- Trial name
- NCT05524948
- Testing
- Experimental Dentifrice, Reference Dentifrice
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- HALEON
Fluorosis, Oral Deseases
12 Month Follow up in Vivo Icon Study on Fluorotic Teeth
Clinical trial to investigate the clinical efficiency of resin infiltration compared to microabrasion in the improvement of dental fluorosis.
- Trial name
- NCT02925780
- Testing
- Resin infiltration, Microabrasion
- Sponsor
- DMG Dental Material Gesellschaft mbH
Dental Fluorosis, Dental Caries
Effect of pH and Fluoride Concentration of Dentifrices on Caries Control
This study aims to assess the overall effect of pH and fluoride concentration of liquid dentifrices in the control of children dental caries of a fluoridated area, through visual inspection and the quantitative light-induced…
- Trial name
- EPHFCDCC (NCT01049503)
- Testing
- Low fluoride and conventional dentifrices with different pH
- Where
- Brazil
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Oral Malodor
Clinical Investigation of Oral Malodor for Max Fresh Toothpaste Containing Zinc Citrate Versus a Commercially Available Regular Fluoride Toothpaste
The objective of this three-week clinical research study is to evaluate oral malodor for a toothpaste containing zinc citrate as compared to a commercially available regular fluoride toothpaste using the organoleptic method.
- Trial name
- NCT07398378
- Testing
- Max Fresh Toothpaste, Colgate Cavity Protection Toothpaste
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Root Caries
Silver Diamine Fluoride Application on Root Caries Fillings
The goal of this clinical trial is to learn the influence of prior silver diamine fluoride (SDF) application on root caries fillings. The main questions to answer 1.
- Trial name
- NCT06514885
- Testing
- SDF solution application, Tonic water
- Where
- Hong Kong
- Volunteers
- 184 people
- Sponsor
- The University of Hong Kong
Dental Caries
Comparative Effectiveness of Treatments to Prevent Dental Caries
Dental caries (tooth decay) is the most prevalent childhood disease in the world. Multiple interventions are available to treat and prevent caries.
- Trial name
- NCT03448107
- Testing
- Silver Diamine Fluoride, Fluoride Varnishes, Glass Ionomer
- Where
- United States
- Volunteers
- 3,345 people, healthy volunteers welcome
- Sponsor
- NYU College of Dentistry
Dental Caries in Children
Water From Bottles to Establish Strong Teeth
The waterBEST study is a proof-of-concept, randomized, double-masked, placebo controlled, parallel group study evaluating dental caries-preventive effects of fluoridated bottled water compared to non-fluoridated bottled water in…
- Trial name
- waterBEST (NCT04893681)
- Testing
- Fluoridated bottled drinking water, Non-fluoridated drinking water
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Head and Neck Cancer, Head and Neck Carcinoma
Post-Radiation Oral Health in Underserved Head and Neck Cancer Patients
This is a pilot study evaluates the feasibility and outcomes of providing fluoride varnish treatment during routine cancer surveillance visits for post-radiation head and neck cancer patients with limited access to dental care.
- Conditions
- Head and Neck Cancer, Head and Neck Carcinoma, Head and Neck Neoplasms
- Trial name
- NCT07556367
- Testing
- Surveys, Saliva Collection, Intra-oral photographs
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of California, San Francisco
Dentin Hypersensitivity, Fluoride
Efficacy of Formulated Eggshell Derived Nano-hydroxyapatite Containing Toothpaste With and Without Addition of Fluoride vs. Conventional Desensitizing Fluoride Containing Toothpaste in Management of Dentin Hypersensitivity
compare the effectiveness of Eggshell derived nano-Hydroxyapatite with and without fluoride and conventional fluoride containing tooth paste versus conventional desensitizing fluoride containing tooth paste on dentinal tubule…
- Conditions
- Dentin Hypersensitivity, Fluoride, Nano-hydroxy Apatite
- Trial name
- NCT06493500
- Testing
- Eggshell derived Nano-hydroxyapatite (n-HAp) with a Fluoride containing toothpaste, Eggshell derived Nano-hydroxyapatite (n-HAp) without a Fluoride containing toothpaste
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Low-back Pain, Nociceptive Pain
PET/CT Guided Robotic Arm-assisted Pain Palliation in Chronic Nociceptive Low Backache
A study to investigate the role of F-18 sodium fluoride in localizing the pain generator in participants with chronic nociceptive musculoskeletal low back ache and to study the use of PET/CT guided robotic arm assisted injection…
- Trial name
- NCT05560165
- Testing
- F-18 sodium fluoride PET/CT guided robotic arm assisted injection of combination of local anesthetic and steroids
- Where
- India
- Volunteers
- 85 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Oral Bacterial Infection
Evaluation of the Antibacterial Effect of a Toothpaste Containing Zinc Lactate
The aim of this study is to evaluate the antibacterial effect 12 hours after 4-week use of a toothpaste containing amine base, zinc lactate, and fluoride.
- Trial name
- NCT05628571
- Testing
- Zinc toothpaste, Fluoride Toothpaste
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Dental Caries
Effect of Water Rinsing After Topical Fluoride Application on Dental Plaque pH
The aim of this study was to determine whether rinsing with water or cleansing teeth after topical fluoride therapy affect the dental plaque pH.
- Trial name
- NCT01569165
- Testing
- cleansing teeth after topical fluoride therapy
- Where
- Iran
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Dental Caries
Comparison of the Salivary Levels of Streptococcus Mutans in Pediatric Patients With Early Childhood Caries After the Application of Silver Diamine Fluoride or 5% Sodium Fluoride Varnish
Comparison of the salivary levels of Streptococcus mutans in pediatric patients with Early Childhood Caries after the application of Silver Diamine Fluoride or 5% Sodium Fluoride Varnish
- Trial name
- NCT03089567
- Testing
- Sodium Fluoride, Silver diamine fluoride
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Dental Caries in Children, Satisfaction
Comparison of Caries Arrested & Prevented Among SDF, NaF Varnish and Combination in Children
Tooth decay is one of the most common chronic infectious disease found in children worldwide and if left untreated, is rapidly progress.
- Conditions
- Dental Caries in Children, Satisfaction, Cost Effectiveness, Oral Health
- Trial name
- NCT03480516
- Testing
- SDF, Fluoride varnish
- Where
- Thailand
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Carotid Artery Plaque
Carotid Plaque Assessment Using 18Fluorine (18F) -Sodium Fluoride Positron Emission Tomography (PET) /MR
Carotid plaque can lead to ischemic stroke. Treatment of asymptomatic carotid plaque, based on degree stenosis, is still controversial.
- Trial name
- CARTIS (NCT02726984)
- Testing
- 18F-sodium fluoride PET/MR
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
White Spot Lesion
Evaluation of Two Varnishes on the Improvement of White Spot Lesions in Children
A randomized control trial evaluating the effect of the Giomer varnish versus fluoride varnish on the color improvement of the white spot lesion in permanent anterior teeth of children aged between 8-14 years by using a…
- Trial name
- NCT05775250
- Testing
- giomer varnish
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Dental Caries
Evaluation of a Low Fluoride Dentifrice for Caries Control
The aim of this randomized clinical trial is to evaluate the effect of pH and fluoride concentration in liquid dentifrices in the control of dental caries in early childhood, in non-fluoridated area.
- Trial name
- NCT01623362
- Testing
- Low-fluoride acidic dentifrice, conventional dentifrice, neutral pH and low-fluoride dentifrice
- Where
- Brazil
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba