Clinical trials: Focal Liver Lesions
Liver Neoplasms
SonoVue®-Enhanced Ultrasound (US) Versus Unenhanced US for Focal Liver Lesion Characterization
The purpose of this study is to demonstrate the Sensitivity and Specificity of SonoVue®-enhanced ultrasound is superior to that of unenhanced ultrasound for the characterization of benign versus malignant FLLs using final…
- Trial name
- NCT00829413
- Testing
- SonoVue®
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- Bracco Diagnostics, Inc
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Interventional AI-Human Collaboration for Liver Tumor Diagnosis
Recent advances in artificial intelligence (AI), particularly deep learning technology, have transformed medical imaging analysis.
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07153783
- Testing
- AI-human collaboration for CE-CTs diagnosis
- Where
- China
- Volunteers
- 10,333 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Focal Liver Lesions, Liver Cancer
Characterization of Focal Liver Lesions by Real-time Contrast-enhanced Ultrasound Imaging (CEUS)
The conventional sonography is frequently used to detect incidental focal liver lesions because of its availability, innocuity and low cost.
- Conditions
- Focal Liver Lesions, Liver Cancer, Liver Cirrhosis
- Trial name
- NCT00243633
- Testing
- Real-time contrast-enhanced ultrasound sonography
- Where
- 15 sites in France
- Volunteers
- 878 people
- Sponsor
- University Hospital, Tours
Focal Liver Lesion
The Role of Ceus in the Characterization of Focal Liver Lesions Indeterminate to Second-level Methods
The primary objective of the study is to determine the accuracy of CEUS in characterizing (as benign or malignant) focal liver lesions for which CT, MRI and/or PET have not been conclusive.
- Trial name
- InFoLIL (NCT06876805)
- Testing
- CEUS or Contrast enhanced Ultrasound
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Liver Cirrhosis
Contrast-Enhanced Ultrasound Imaging in Diagnosing Liver Cancer in Patients With Cirrhosis
This clinical trial studies how well contrast-enhanced ultrasound imaging works in diagnosing liver cancer in patients with cirrhosis.
- Trial name
- NCT03318380
- Testing
- Dynamic Contrast-Enhanced Ultrasound Imaging
- Where
- 11 sites in United States, Canada and 4 more
- Volunteers
- 612 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Hepatocellular Carcinoma, Cholangiocarcinoma, Intrahepatic
Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study
Aim of this prospective national multicenter study is to improve standardization of contrast-enhanced ultrasound (CEUS) in the non-invasive diagnosis of hepatocellular carcinoma (HCC) in high-risk patients.
- Conditions
- Hepatocellular Carcinoma, Cholangiocarcinoma, Intrahepatic, Liver Cirrhosis, Liver Cancer
- Trial name
- ESCULAP (NCT03405909)
- Testing
- contrast enhanced ultrasound (CEUS), MRI, Histology
- Where
- Germany
- Volunteers
- 517 people
- Sponsor
- University Hospital Erlangen
Focal Nodular Hyperplasia of Liver, Toxic Liver Disease With Focal Nodular Hyperplasia
Contrast Enhanced Ultrasound For The Evaluation Of Focal Liver Lesions
The aim of the study is to assess the value of contrast enhanced ultrasound in the evaluation of de novo focal liver lesions in clinical practice, in a prospective multi-center design.
- Conditions
- Focal Nodular Hyperplasia of Liver, Toxic Liver Disease With Focal Nodular Hyperplasia, Liver Metastases
- Trial name
- HepFocUS (NCT01329458)
- Where
- 5 sites in Romania
- Volunteers
- 1,500 people
- Sponsor
- Societatea Romana de Ultrasonografie in Medicina si Biologie
Hepatocellular Carcinoma
Application Value of CEUS Li-RADS in Hepatic Focal Lesions in Patients With Non-high Risk Factors for HCC
Currently, there are few studies on the diagnostic ability of CEUS-LI-RADS in patients with non-high risk factors for liver nodules. Whether this classification is applicable to such patients remains controversial.
- Trial name
- NCT04920214
- Testing
- SonoVue
- Where
- 10 sites in China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Liver Neoplasms, Adenoma
Liver MRI With Primovist/Eovist in Pediatric Subjects Who Are Suspected or Have Focal Liver Lesions.
Medical records are reviewed to obtain information about the use of a MRI diagnostic imaging agent (contrast agent) called Primovist/Eovist in children older than 2 months and less than 18 years.
- Conditions
- Liver Neoplasms, Adenoma, Carcinoma, Liver Abscess
- Trial name
- NCT01043523
- Testing
- Gadoxetic Acid Disodium (Eovist, BAY86-4873)
- Where
- 9 sites in United States, Italy and 3 more
- Volunteers
- 52 people
- Sponsor
- Bayer
Lung; Nodule, Liver Metastases
Study of Different Gating Techniques for PET Image of Lung and Liver Lesions
Lesions blurred by respiratory motion are common in fluorine-18 PET/CT studies. To avoid these artefacts, several standard gating correction technics are available.
- Trial name
- PETGATQUANT (NCT05779865)
- Where
- Monaco
- Volunteers
- 29 people
- Sponsor
- Centre Hospitalier Princesse Grace
Known or Suspected Focal Liver Lesions
Efficacy and Safety of Primovist in Chinese Patients
Participants who had been diagnosed or suspected by doctors to have focal liver lesions that need further evaluation in order to make an accurate diagnosis.
- Trial name
- NCT00526188
- Testing
- Gadoxetic Acid Disodium (Primovist, BAY86-4873)
- Where
- 6 sites in China
- Volunteers
- 234 people
- Sponsor
- Bayer
Liver Diseases, Magnetic Resonance Imaging
High Resolution HBA-MRI Using Deep Learning Reconstruction
This study aims to compare image qualities between conventionally reconstructed MRI sequences and deep-learning reconstructed MRI sequences from the same data in patients who undergo Gd-EOB-DTPA enhanced liver MRI.
- Conditions
- Liver Diseases, Magnetic Resonance Imaging, Deep Learning
- Trial name
- NCT05182099
- Testing
- Liver MRI
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Seoul National University Hospital
Hepatic Neoplasms
Identification of Hepatic Lesions
Patients with suspicion of primary or secondary hepatic malignancy in whom a radiological examination is needed in order to decide on the most appropriate treatment.
- Trial name
- NCT00307866
- Testing
- Resovist (BAY86-4884, SH U 555 A)
- Where
- 19 sites in Italy
- Volunteers
- 218 people
- Sponsor
- Bayer
Liver Neoplasms
A Trial on Contrast-enhanced Ultrasound Versus Conventional Ultrasound Guided Biopsy of Liver Neoplasms
The purpose of this study is to estimate the clinical value of contrast-enhanced ultrasound in percutaneous biopsy for liver occupied lesion.
- Trial name
- NCT02413437
- Testing
- CEUS guided biopsy, US guided biopsy, Ultrasound
- Where
- China
- Volunteers
- 2,088 people
- Sponsor
- Peking University Cancer Hospital & Institute
Ultrasound
Prospective Multicenter Study on Clinical Application of Sonazoid in Liver Tumor
Sonazoid as a new generation of ultrasound contrast agent.This study based on the features of Sonazoid specific angiography and his mechanical index, the role of Sonazoidin in the differential diagnosis of benign and malignant…
- Trial name
- NCT04563897
- Volunteers
- 1,300 people
- Sponsor
- Chinese PLA General Hospital
Hepatocellular Carcinoma
Fusion Imaging Contrast-enhanced Ultrasound LI-RADS
CEUS LI-RASD apply to lesion visible at precontrast ultrasound but not the lesion invisible. Fusion imaging can use to invisible lesions at precontrast ultrasound in clinical practice.
- Trial name
- NCT04955119
- Testing
- Fusion imaging contrast-enhanced ultrasound
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Tianjin Third Central Hospital
Focal Liver Lesion
CT Image-assisted Detection Software for Focal Liver Lesions
To evaluate the safety and effectiveness of the developed and produced CT image-assisted detection software for focal liver lesions before being put into the market.
- Trial name
- MRMC (NCT06068413)
- Testing
- CT image-assisted detection software
- Where
- China
- Volunteers
- 376 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Contrast Media, Liver, Biopsy, Fusion
Added Value in Combined Use of Fusion Imaging and Contrast-enhanced Ultrasonography
So far, there have been studies showing that the CEUS-grafted technique has added value in biopsy and RFA, but no studies have compared the group using only fusion and the group using CEUS+fusion.
- Trial name
- NCT04487288
- Testing
- SONAZOID
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital