Clinical trials: Focus
Peripheral Arterial Disease, Peripheral Vascular Diseases
Real World Registry Assessing the Clinical Use of the Bard UltraScore Forced Focus PTA Balloon
The objective of this study is to assess the clinical use of the Bard® UltraScore™ Focused Force PTA balloon in a heterogeneous patient population in a real world, on-label clinical application.
- Conditions
- Peripheral Arterial Disease, Peripheral Vascular Diseases, Arterial Occlusive Diseases
- Trial name
- NCT03193619
- Testing
- PTA (UltraScore Focused Force PTA Balloon)
- Where
- 31 sites in United States
- Volunteers
- 350 people
- Sponsor
- C. R. Bard
Palliative Care, Critical Illness
A Needs-focused Palliative Care Intervention for Older Adults in ICUs
The quality of intensive care unit (ICU)-based palliative care is highly variable, particularly for the 2 million older adults admitted annually to ICUs.
- Conditions
- Palliative Care, Critical Illness, Aging, Care Delivery Model
- Trial name
- PCplanner (NCT04414787)
- Testing
- PCplanner
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Duke University
Headache, Migraine
Sphenopalatine Nerve Block for Headache Tx360
The primary objective of this study is to evaluate the efficacy of sphenopalatine nerve block utilizing the Tx360 (device) to deliver an anesthetic agent (bupivacaine) and to assess the duration of the analgesia.
- Trial name
- NCT01939314
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Indiana University
Breast Cancer, Invasive Ductal
Efficacy of Magnetic Resonance-guided High Intensity Focused Ultrasound for the Ablation of Breast Cancer
The purpose of the study is to evaluate the efficacy of a dedicated Magnetic Resonance guided High Intensity Focused Ultrasound (MR-HIFU) unit in ablating breast cancer by comparing MR imaging and pathologic specimen after…
- Trial name
- NCT03560102
- Testing
- Philips Sonalleve® MR-HIFU Breast Therapy System
- Where
- Switzerland
- Volunteers
- 1 people
- Sponsor
- Kantonsspital Winterthur KSW
Achilles Tendinopathy
Ultrasound-Monitored Changes in Achilles Tendinopathy After Extracorporeal Shock Wave Therapy
This study is designed as a randomized, placebo-controlled clinical trial in which we monitor the effects of low-energy focused extracorporeal shockwave therapy (ESWT) in patients with Achilles tendinopathy (AT).
- Trial name
- NCT04780919
- Testing
- BTL-6000 FSWT
- Where
- Czechia
- Volunteers
- 18 people
- Sponsor
- University Hospital, Motol
Sarcoma, Soft Tissue
Evaluation of Side Effects and Relative Activity of Two Chemotherapy Regimens in the Treatment Soft Tissue Sarcoma
The purpose of this study is to explore how a sarcoma is affected by and the side effects of a newer combination of chemotherapy drugs(gemcitabine and docetaxel)as compared to a standard combination of chemotherapy drugs…
- Trial name
- NCT00189137
- Testing
- ifosfamide and doxorubicin vs gemcitabine and docetaxel
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Michigan Rogel Cancer Center
Adenocarcinoma Pancreas
Pilot, Neoadjuvant Gemcitabine and Abraxane Chemotherapy Followed by Surgery, Adenocarcinoma of the Pancreas
This study is for adult patients with adenocarcinoma of the pancreas. The purpose of this research study is to evaluate the safety and effectiveness of the drugs Gemcitabine and Abraxane in the treatment of adenocarcinoma of the…
- Trial name
- NCT01783054
- Testing
- Surgery, Genetic Expression, Chemotherapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Medical University of South Carolina
Prostate Cancer
Enhancing Survivorship Care Planning for Patients With Localized Prostate Cancer Using A Couple-focused Web-based Tailored Symptom Self-management Program
The purpose of this research study is to examine the feasibility of the enhanced survivorship care plans (ESCPs, regular SCPs with the a web-based couple-focused symptom self-management project (PERC) or National Cancer Institute…
- Trial name
- SCP (NCT04350788)
- Testing
- Survivorship Care Plan, Enhanced Survivorship Care Plan
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Brain Tumor
Blood-Brain Barrier Disruption Using Transcranial MRI-Guided Focused Ultrasound
The purpose of this study is to evaluate the safety of BBB disruption using transcranial MRI-guided focused ultrasound in conjunction with an intravenous ultrasound contrast agent to increase the accumulation of doxorubicin in…
- Trial name
- NCT02343991
- Testing
- Transcranial ExABlate
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- InSightec
Posttraumatic Stress Disorder
Trauma-Focused Equine-Assisted Therapy (TF-EAT) for Veterans With PTSD
This study seeks to examine feasibility, acceptability, safety, and preliminary efficacy of Equine-Assisted Therapy for veterans with posttraumatic stress disorder (EAT-PTSD).
- Trial name
- TF-EAT (NCT03068325)
- Testing
- EAT-PTSD
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Lymphoma
S0313 Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, and Radiation Therapy Followed By Rituximab and Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Stage I or Stage II Non-Hodgkin's Lymphoma
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, doxorubicin, vincristine, and prednisone, use different ways to stop cancer cells from dividing so they stop growing or die.
- Trial name
- NCT00070018
- Testing
- rituximab, Cyclophosphamide, doxorubicin hydrochloride
- Where
- 48 sites in United States
- Volunteers
- 46 people
- Sponsor
- SWOG Cancer Research Network